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Coexpression cluster:C142

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Full id: C142_Preadipocyte_Fibroblast_hepatic_Ewing_Adipocyte_Olfactory_Hair



Phase1 CAGE Peaks

  Short description
Hg19::chr15:39873268..39873287,+ p1@THBS1
Hg19::chr15:39873352..39873390,- p@chr15:39873352..39873390
-
Hg19::chr15:39874384..39874412,+ p@chr15:39874384..39874412
+
Hg19::chr15:39874415..39874435,+ p@chr15:39874415..39874435
+
Hg19::chr15:39874416..39874433,- p@chr15:39874416..39874433
-
Hg19::chr15:39874450..39874555,+ p@chr15:39874450..39874555
+
Hg19::chr15:39874545..39874592,- -
p@chr15:39874545..39874592
Hg19::chr15:39874573..39874603,+ p@chr15:39874573..39874603
+
Hg19::chr15:39874611..39874645,- p@chr15:39874611..39874645
-
Hg19::chr15:39874624..39874636,+ p@chr15:39874624..39874636
+
Hg19::chr15:39874646..39874658,+ p@chr15:39874646..39874658
+
Hg19::chr15:39874647..39874660,- p@chr15:39874647..39874660
-
Hg19::chr15:39874673..39874718,+ p@chr15:39874673..39874718
+
Hg19::chr15:39874750..39874781,- p@chr15:39874750..39874781
-
Hg19::chr15:39874775..39874799,+ +
p@chr15:39874775..39874799
Hg19::chr15:39874801..39874813,+ p@chr15:39874801..39874813
+
Hg19::chr15:39874814..39874827,+ p@chr15:39874814..39874827
+
Hg19::chr15:39874833..39874882,- p@chr15:39874833..39874882
-
Hg19::chr15:39874839..39874842,+ p@chr15:39874839..39874842
+
Hg19::chr15:39874845..39874911,+ p@chr15:39874845..39874911
+
Hg19::chr15:39874927..39874939,+ p@chr15:39874927..39874939
+
Hg19::chr15:39875809..39875867,+ p@chr15:39875809..39875867
+
Hg19::chr15:39876176..39876314,+ p@chr15:39876176..39876314
+
Hg19::chr15:39876228..39876300,- p@chr15:39876228..39876300
-
Hg19::chr15:39876325..39876356,+ p@chr15:39876325..39876356
+
Hg19::chr15:39876334..39876355,- p@chr15:39876334..39876355
-
Hg19::chr15:39876490..39876590,+ +
p@chr15:39876490..39876590
Hg19::chr15:39876528..39876544,- p@chr15:39876528..39876544
-
Hg19::chr15:39876566..39876609,- p@chr15:39876566..39876609
-
Hg19::chr15:39876615..39876625,- p@chr15:39876615..39876625
-
Hg19::chr15:39877655..39877744,+ p15@THBS1
Hg19::chr15:39877742..39877767,- p@chr15:39877742..39877767
-
Hg19::chr15:39879545..39879692,+ p7@THBS1
Hg19::chr15:39879648..39879683,- p@chr15:39879648..39879683
-
Hg19::chr15:39880241..39880341,+ p8@THBS1
Hg19::chr15:39880315..39880385,- p@chr15:39880315..39880385
-
Hg19::chr15:39880345..39880367,+ p19@THBS1
Hg19::chr15:39880370..39880395,+ p25@THBS1
Hg19::chr15:39880723..39880752,+ p2@THBS1
Hg19::chr15:39880753..39880767,+ p9@THBS1
Hg19::chr15:39880777..39880827,+ p3@THBS1
Hg19::chr15:39880843..39880887,- p@chr15:39880843..39880887
-
Hg19::chr15:39880854..39880863,+ p35@THBS1
Hg19::chr15:39881152..39881262,+ p4@THBS1
Hg19::chr15:39881200..39881244,- p@chr15:39881200..39881244
-
Hg19::chr15:39881392..39881514,+ p@chr15:39881392..39881514
+
Hg19::chr15:39881480..39881526,- p@chr15:39881480..39881526
-
Hg19::chr15:39881517..39881536,+ p@chr15:39881517..39881536
+
Hg19::chr15:39881528..39881548,- p@chr15:39881528..39881548
-
Hg19::chr15:39881997..39882024,+ p@chr15:39881997..39882024
+
Hg19::chr15:39882038..39882076,+ p@chr15:39882038..39882076
+
Hg19::chr15:39882038..39882106,- -
p@chr15:39882038..39882106
Hg19::chr15:39882120..39882131,- p@chr15:39882120..39882131
-
Hg19::chr15:39882147..39882159,+ p@chr15:39882147..39882159
+
Hg19::chr15:39882160..39882178,+ +
p@chr15:39882160..39882178
Hg19::chr15:39882174..39882185,- p@chr15:39882174..39882185
-
Hg19::chr15:39882188..39882206,+ p@chr15:39882188..39882206
+
Hg19::chr15:39882711..39882733,+ p14@THBS1
Hg19::chr15:39882740..39882785,+ p6@THBS1
Hg19::chr15:39882788..39882816,- p@chr15:39882788..39882816
-
Hg19::chr15:39883385..39883407,+ p5@THBS1
Hg19::chr15:39883443..39883468,+ p10@THBS1
Hg19::chr15:39883501..39883528,- p@chr15:39883501..39883528
-
Hg19::chr15:39883509..39883520,+ p23@THBS1
Hg19::chr15:39883697..39883741,+ p@chr15:39883697..39883741
+
Hg19::chr15:39883769..39883790,+ p@chr15:39883769..39883790
+
Hg19::chr15:39884760..39884827,+ p17@THBS1
Hg19::chr15:39884839..39884858,+ p29@THBS1
Hg19::chr15:39884859..39884872,+ p36@THBS1
Hg19::chr15:39884872..39884923,- p@chr15:39884872..39884923
-
Hg19::chr15:39884878..39884898,+ p30@THBS1
Hg19::chr15:39884901..39884916,+ p22@THBS1
Hg19::chr15:39884917..39884949,+ p24@THBS1
Hg19::chr15:39884924..39884945,- p@chr15:39884924..39884945
-
Hg19::chr15:39884950..39884967,+ p28@THBS1
Hg19::chr15:39885197..39885322,+ p13@THBS1
Hg19::chr15:39885323..39885396,+ p16@THBS1
Hg19::chr15:39885590..39885644,+ p20@THBS1
Hg19::chr15:39885653..39885673,+ p32@THBS1
Hg19::chr15:39885701..39885737,+ p27@THBS1
Hg19::chr15:39885742..39885808,+ p18@THBS1
Hg19::chr15:39885810..39885845,+ p21@THBS1
Hg19::chr15:39886290..39886353,+ p11@THBS1
Hg19::chr15:39886357..39886368,+ p31@THBS1
Hg19::chr15:39886495..39886505,+ p39@THBS1
Hg19::chr15:39886511..39886611,+ p12@THBS1
Hg19::chr15:39887636..39887649,+ p@chr15:39887636..39887649
+
Hg19::chr15:39887636..39887649,- p@chr15:39887636..39887649
-
Hg19::chr15:39887667..39887675,+ p@chr15:39887667..39887675
+
Hg19::chr15:39887702..39887713,+ p@chr15:39887702..39887713
+
Hg19::chr15:39887744..39887747,+ p@chr15:39887744..39887747
+
Hg19::chr15:39887886..39887897,+ p@chr15:39887886..39887897
+
Hg19::chr15:39887918..39887929,+ p@chr15:39887918..39887929
+
Hg19::chr15:39887951..39887958,+ p@chr15:39887951..39887958
+
Hg19::chr15:39887969..39887972,+ p@chr15:39887969..39887972
+
Hg19::chr15:39888008..39888026,+ p@chr15:39888008..39888026
+
Hg19::chr15:39888011..39888097,- p@chr15:39888011..39888097
-
Hg19::chr15:39888029..39888054,+ p@chr15:39888029..39888054
+
Hg19::chr15:39888070..39888084,+ p@chr15:39888070..39888084
+
Hg19::chr15:39888092..39888103,+ p@chr15:39888092..39888103
+
Hg19::chr15:39888108..39888125,+ p@chr15:39888108..39888125
+
Hg19::chr15:39888129..39888145,+ p@chr15:39888129..39888145
+
Hg19::chr15:39888147..39888161,+ p@chr15:39888147..39888161
+
Hg19::chr15:39888222..39888232,+ p@chr15:39888222..39888232
+
Hg19::chr15:39888305..39888312,+ p@chr15:39888305..39888312
+
Hg19::chr15:39888341..39888350,+ p@chr15:39888341..39888350
+
Hg19::chr15:39888375..39888402,- p@chr15:39888375..39888402
-
Hg19::chr15:39888386..39888393,+ p@chr15:39888386..39888393
+
Hg19::chr15:39888428..39888447,+ p@chr15:39888428..39888447
+
Hg19::chr15:39888451..39888489,+ p@chr15:39888451..39888489
+
Hg19::chr15:39888509..39888542,+ p@chr15:39888509..39888542
+
Hg19::chr15:39888616..39888632,+ p@chr15:39888616..39888632
+
Hg19::chr15:39888645..39888657,+ p@chr15:39888645..39888657
+
Hg19::chr15:39888667..39888675,+ p@chr15:39888667..39888675
+
Hg19::chr15:39888763..39888780,+ p@chr15:39888763..39888780
+
Hg19::chr15:39888814..39888825,+ p@chr15:39888814..39888825
+
Hg19::chr15:39888860..39888866,+ +
p@chr15:39888860..39888866
Hg19::chr15:39888868..39888879,+ p@chr15:39888868..39888879
+
Hg19::chr15:39888881..39888913,+ p@chr15:39888881..39888913
+
Hg19::chr15:39888950..39888983,+ p@chr15:39888950..39888983
+
Hg19::chr15:39888995..39889015,+ p@chr15:39888995..39889015
+
Hg19::chr15:39889494..39889515,+ p1@BC015134
Hg19::chr1:231005310..231005347,- p2@C1orf198


Enriched pathways on this co-expression cluster
Summary:


Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset


data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster
Summary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner



link to source dataset


data

GO IDGO nameFDR corrected p-value
GO:0008201heparin binding0.0154244672082892
GO:0007596blood coagulation0.0154244672082892
GO:0050817coagulation0.0154244672082892
GO:0007599hemostasis0.0154244672082892
GO:0005539glycosaminoglycan binding0.0154244672082892
GO:0030247polysaccharide binding0.0154244672082892
GO:0050878regulation of body fluid levels0.0154244672082892
GO:0001871pattern binding0.0154244672082892
GO:0042060wound healing0.0154244672082892
GO:0004866endopeptidase inhibitor activity0.0256253813300793
GO:0030414protease inhibitor activity0.0256253813300793
GO:0051674localization of cell0.0298834334157541
GO:0006928cell motility0.0298834334157541
GO:0004857enzyme inhibitor activity0.0298834334157541
GO:0009611response to wounding0.0298834334157541
GO:0030246carbohydrate binding0.0316584245849523
GO:0009605response to external stimulus0.039458100442579
GO:0007399nervous system development0.042152360767691
GO:0065008regulation of biological quality0.0484432557904829
GO:0022610biological adhesion0.0484432557904829
GO:0007155cell adhesion0.0484432557904829



Enriched sample ontology terms on this co-expression cluster
Summary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji



links to source dataset

cell_data
uberon_data



Uber Anatomy
Ontology termp-valuen
splanchnic layer of lateral plate mesoderm8.18e-2183
vasculature1.06e-2078
vascular system1.06e-2078
vessel2.99e-2068
epithelial tube open at both ends7.61e-1959
blood vessel7.61e-1959
blood vasculature7.61e-1959
vascular cord7.61e-1959
cardiovascular system2.65e-15109
circulatory system1.10e-14112
artery2.76e-1442
arterial blood vessel2.76e-1442
arterial system2.76e-1442
epithelial tube6.39e-14117
multi-cellular organism5.72e-11656
blood vessel endothelium8.53e-1118
endothelium8.53e-1118
cardiovascular system endothelium8.53e-1118
mesoderm8.57e-11315
mesoderm-derived structure8.57e-11315
presumptive mesoderm8.57e-11315
anatomical system1.20e-10624
anatomical group1.65e-10625
unilaminar epithelium4.19e-10148
systemic artery4.63e-1033
systemic arterial system4.63e-1033
simple squamous epithelium8.49e-1022
organ component layer9.79e-1066
surface structure1.47e-0999
squamous epithelium1.92e-0925
multilaminar epithelium2.08e-0883
lateral plate mesoderm3.37e-08203
integument5.75e-0846
integumental system5.75e-0846
extraembryonic membrane7.50e-0814
membranous layer7.50e-0814
aorta9.80e-0821
aortic system9.80e-0821
skin of body1.49e-0741
epithelial vesicle4.21e-0778


Overrepresented TFBS (DNA) motifs on this co-expression cluster
Summary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs

data

Novel motifs


JASPAR motifs
Motifs-log10(p-value)
MA0003.10
MA0004.11.1297
MA0006.10.0200673
MA0007.10.0131667
MA0009.10.0648329
MA0014.14.67385e-12
MA0017.10.796663
MA0019.10.799393
MA0024.10.0347815
MA0025.10.119326
MA0027.11.35443
MA0028.10.000187727
MA0029.13.01129
MA0030.10.036646
MA0031.10.0231186
MA0038.10.0583086
MA0040.14.35396
MA0041.13.52541
MA0042.13.09514
MA0043.10.0649406
MA0046.13.57853
MA0048.10.063681
MA0050.11.04874
MA0051.10.611655
MA0052.10.162308
MA0055.10.0369432
MA0056.10
MA0057.16.58011e-05
MA0058.10.575971
MA0059.13.89752
MA0060.10.0957268
MA0061.10.000583932
MA0063.10
MA0066.10.00298794
MA0067.10.221564
MA0068.19.23865e-07
MA0069.10.21676
MA0070.10.0563391
MA0071.10.0112543
MA0072.10.445517
MA0073.10
MA0074.10.0555216
MA0076.10.000962384
MA0077.12.73874
MA0078.10.460146
MA0081.10.111827
MA0083.10.0674221
MA0084.10.351402
MA0087.11.65172
MA0088.17.34493e-05
MA0089.10
MA0090.10.951608
MA0091.11.43733
MA0092.13.6398
MA0093.10.930006
MA0095.10
MA0098.10
MA0100.14.91711
MA0101.10.592699
MA0103.10.1802
MA0105.15.18661e-07
MA0106.11.41277
MA0107.10.00374648
MA0108.20.457292
MA0109.10
MA0111.10.811795
MA0113.10.00608844
MA0114.10.414954
MA0115.10.17564
MA0116.10.0417623
MA0117.10.0783765
MA0119.111.934
MA0122.10.0885433
MA0124.10.464574
MA0125.10.724749
MA0130.10
MA0131.10.0109292
MA0132.10
MA0133.10
MA0135.10.262001
MA0136.10.0624129
MA0139.10.000322713
MA0140.10.0108672
MA0141.10.00309669
MA0142.10.655267
MA0143.10.37242
MA0144.12.20228
MA0145.10.00983413
MA0146.10
MA0147.10.366606
MA0148.10.131899
MA0149.10.00140319
MA0062.21.26265e-07
MA0035.20.0107662
MA0039.20
MA0138.29.73932
MA0002.20.397224
MA0137.20.0309512
MA0104.20.275159
MA0047.21.01717
MA0112.21.74265e-07
MA0065.20.0820749
MA0150.10.0855784
MA0151.10
MA0152.10.0118417
MA0153.10.103429
MA0154.10.0403968
MA0155.11.00908e-10
MA0156.10.0642643
MA0157.10.0140884
MA0158.10
MA0159.10.0113977
MA0160.10.00813773
MA0161.10
MA0162.11.44649e-16
MA0163.10
MA0164.10.00699867
MA0080.20.0445574
MA0018.20.0285959
MA0099.20.50752
MA0079.20
MA0102.20.37965
MA0258.12.11694e-05
MA0259.10.408998
MA0442.10


ENCODE TF ChIP-seq peak enrichment analysis
Summary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner



link to source dataset


data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
ESR1#2099153.752268694652991.20118707854347e-050.000300841192556358
GATA3#2625112.435786015685090.005780435976705730.0259936685886402
POLR2A#54301222.129994207642962.02515758995374e-391.14948605183249e-36



Relative expression of the co-expression cluster
Summary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data