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MCL coexpression mm9:494

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:80081699..80081706,-p15@Tmem229b
Mm9::chr13:56237443..56237448,-p15@H2afy
Mm9::chr16:32179862..32179874,+p2@Bex6
Mm9::chr16:32179880..32179921,+p1@Bex6
Mm9::chr16:49857993..49858003,+p@chr16:49857993..49858003
+
Mm9::chr16:92826016..92826027,-p@chr16:92826016..92826027
-
Mm9::chr16:92826036..92826066,-p@chr16:92826036..92826066
-
Mm9::chr3:135271325..135271343,-p15@Nfkb1
Mm9::chr3:137660739..137660743,-p@chr3:137660739..137660743
-
Mm9::chr3:51592897..51592913,+p@chr3:51592897..51592913
+
Mm9::chr3:68495352..68495360,+p3@Il12a
Mm9::chr8:82919099..82919104,-p@chr8:82919099..82919104
-
Mm9::chr8:97544774..97544791,+p@chr8:97544774..97544791
+
Mm9::chr8:97544803..97544843,+p@chr8:97544803..97544843
+
Mm9::chrX:38753893..38753906,+p6@Gria3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0042163interleukin-12 beta subunit binding0.0270640442666959
GO:0045083negative regulation of interleukin-12 biosynthetic process0.0270640442666959
GO:0005143interleukin-12 receptor binding0.0270640442666959
GO:0019972interleukin-12 binding0.0324724047235415
GO:0043514interleukin-12 complex0.0324724047235415
GO:0001740Barr body0.0391268735838529
GO:0002376immune system process0.0391268735838529
GO:0048266behavioral response to pain0.0411605921091782
GO:0035162embryonic hemopoiesis0.0411605921091782
GO:0000805X chromosome0.0411605921091782
GO:0042090interleukin-12 biosynthetic process0.0411605921091782
GO:0045766positive regulation of angiogenesis0.0411605921091782
GO:0045075regulation of interleukin-12 biosynthetic process0.0411605921091782
GO:0048534hemopoietic or lymphoid organ development0.0411605921091782
GO:0002520immune system development0.0441554987038445
GO:0007549dosage compensation0.045620555825299
GO:0042036negative regulation of cytokine biosynthetic process0.0463256521329975
GO:0032615interleukin-12 production0.0463256521329975
GO:0048265response to pain0.0463256521329975
GO:0016566specific transcriptional repressor activity0.0463256521329975
GO:0001739sex chromatin0.0463256521329975
GO:0000803sex chromosome0.0478983747889359



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
hemolymphoid system1.95e-1848
immune system1.95e-1848
hemopoietic organ5.30e-1829
immune organ5.30e-1829
hematopoietic system8.09e-1845
blood island8.09e-1845
thymus4.82e-1523
neck4.82e-1523
respiratory system epithelium4.82e-1523
hemolymphoid system gland4.82e-1523
pharyngeal epithelium4.82e-1523
thymic region4.82e-1523
pharyngeal gland4.82e-1523
entire pharyngeal arch endoderm4.82e-1523
thymus primordium4.82e-1523
early pharyngeal endoderm4.82e-1523
mixed endoderm/mesoderm-derived structure2.52e-1435
pharynx2.63e-1424
gland of gut2.63e-1424
upper respiratory tract2.63e-1424
chordate pharynx2.63e-1424
pharyngeal arch system2.63e-1424
pharyngeal region of foregut2.63e-1424
segment of respiratory tract2.01e-1227
lateral plate mesoderm2.30e-1087
organ segment5.44e-0935
craniocervical region1.14e-0836
respiratory tract2.63e-0741
respiratory system4.50e-0742
anterior region of body7.51e-0743
gut epithelium7.77e-0755


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0017772
MA0004.10.67248
MA0006.10.118059
MA0007.10.227553
MA0009.10.623671
MA0014.10.0171266
MA0017.10.135289
MA0019.10.456268
MA0024.10.582844
MA0025.10.845702
MA0027.12.24512
MA0028.10.12472
MA0029.10.562703
MA0030.10.568779
MA0031.10.535959
MA0038.10.358622
MA0040.10.635404
MA0041.10.536212
MA0042.10.513077
MA0043.10.71494
MA0046.10.657417
MA0048.10.0239691
MA0050.12.09884
MA0051.10.959772
MA0052.12.62605
MA0055.10.229093
MA0056.10
MA0057.10.226212
MA0058.10.968034
MA0059.10.522737
MA0060.10.071412
MA0061.10.295622
MA0063.10
MA0066.10.349199
MA0067.10.953264
MA0068.10.235061
MA0069.10.643292
MA0070.10.634186
MA0071.10.269487
MA0072.10.626238
MA0073.14.6864
MA0074.10.318792
MA0076.10.148159
MA0077.10.605975
MA0078.10.395048
MA0081.10.193203
MA0083.10.714187
MA0084.11.27474
MA0087.10.673355
MA0088.10.143884
MA0089.10
MA0090.11.79613
MA0091.10.696557
MA0092.10.213012
MA0093.11.31516
MA0095.10
MA0098.10
MA0100.10.309116
MA0101.10.182791
MA0103.10.14251
MA0105.10.0373599
MA0106.10.401864
MA0107.10.138378
MA0108.20.476838
MA0109.10
MA0111.10.223614
MA0113.10.377232
MA0114.10.0864402
MA0115.10.717599
MA0116.10.37608
MA0117.10.686999
MA0119.10.183219
MA0122.10.705806
MA0124.10.901619
MA0125.10.830088
MA0130.10
MA0131.10.452196
MA0132.10
MA0133.10
MA0135.10.749615
MA0136.10.891604
MA0139.10.0558308
MA0140.10.30902
MA0141.10.920442
MA0142.10.522654
MA0143.10.391481
MA0144.11.03477
MA0145.10.160233
MA0146.10.000953111
MA0147.10.651622
MA0148.10.252062
MA0149.10.18682
MA0062.20.0394542
MA0035.20.84095
MA0039.20.242567
MA0138.20.445088
MA0002.22.83798
MA0137.20.153989
MA0104.20.495875
MA0047.20.941296
MA0112.20.0599393
MA0065.20.160972
MA0150.10.227466
MA0151.10
MA0152.10.358055
MA0153.11.80563
MA0154.10.247047
MA0155.10.189024
MA0156.10.45173
MA0157.10.493416
MA0158.10
MA0159.10.101261
MA0160.10.254455
MA0161.10
MA0162.10.00971175
MA0163.10.00798568
MA0164.10.335886
MA0080.21.97848
MA0018.20.344133
MA0099.21.1194
MA0079.20.00553644
MA0102.21.32652
MA0258.10.572032
MA0259.10.0890842
MA0442.10
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