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Coexpression cluster:C3834

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Full id: C3834_Endothelial_Hepatic_Renal_Lymphatic_mature_lung_Mesenchymal



Phase1 CAGE Peaks

  Short description
Hg19::chr19:7861475..7861491,+ p@chr19:7861475..7861491
+
Hg19::chr1:172926077..172926120,- p@chr1:172926077..172926120
-
Hg19::chr20:23065602..23065628,- p@chr20:23065602..23065628
-


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
endothelial cell1.37e-8236
endothelial cell of vascular tree8.75e-7024
meso-epithelial cell2.09e-6545
blood vessel endothelial cell2.22e-5018
embryonic blood vessel endothelial progenitor cell2.22e-5018
lining cell5.46e-5058
barrier cell5.46e-5058
vein endothelial cell1.19e-476
fenestrated cell3.71e-255
glomerular endothelial cell3.71e-255
endothelial cell of umbilical vein8.73e-253
mesodermal cell1.36e-24121
endothelial cell of artery7.96e-219
lymphangioblast8.67e-216
endothelial cell of lymphatic vessel8.67e-216
vascular lymphangioblast8.67e-216
glomerular cell4.78e-187
kidney corpuscule cell4.78e-187
squamous epithelial cell4.42e-1363
aortic endothelial cell4.98e-126
kidney cortical cell1.32e-1012
renal cortical epithelial cell1.32e-1012
embryonic cell7.41e-10250
epithelial cell1.09e-08253
epithelial cell of nephron1.64e-0815
kidney cell1.60e-0717
kidney epithelial cell1.60e-0717
Uber Anatomy
Ontology termp-valuen
blood vessel endothelium2.22e-5018
endothelium2.22e-5018
cardiovascular system endothelium2.22e-5018
simple squamous epithelium6.70e-4122
squamous epithelium8.88e-3625
vein1.19e-319
venous blood vessel1.19e-319
venous system1.19e-319
vessel2.71e-2668
vasculature1.51e-2278
vascular system1.51e-2278
endothelial tube7.96e-219
arterial system endothelium7.96e-219
endothelium of artery7.96e-219
primitive nephron4.78e-187
renal glomerulus4.78e-187
renal corpuscle4.78e-187
glomerular capsule4.78e-187
metanephric mesenchyme4.78e-187
glomerular tuft4.78e-187
S-shaped body4.78e-187
renal vesicle4.78e-187
comma-shaped body4.78e-187
epithelial tube open at both ends6.39e-1759
blood vessel6.39e-1759
blood vasculature6.39e-1759
vascular cord6.39e-1759
mesonephric epithelium8.07e-168
mesonephric tubule8.07e-168
nephric duct8.07e-168
renal duct8.07e-168
mesonephric duct8.07e-168
pronephric duct8.07e-168
lymphatic vessel1.18e-158
lymph vasculature1.18e-158
lymphatic part of lymphoid system1.18e-158
cardiovascular system2.71e-15109
umbilical vein4.12e-155
circulatory system8.35e-15112
epithelial tube4.34e-14117
mesonephros4.38e-149
pronephros4.38e-149
nephrogenic cord4.38e-149
pronephric mesoderm4.38e-149
rostral part of nephrogenic cord4.38e-149
presumptive pronephric mesoderm4.38e-149
splanchnic layer of lateral plate mesoderm1.61e-1383
parenchyma6.24e-1315
lymphoid system1.45e-1210
urogenital ridge1.48e-1111
cortex of kidney1.32e-1012
renal parenchyma1.32e-1012
intraembryonic coelom1.32e-1012
duct3.59e-1019
anatomical conduit2.64e-09240
lateral plate mesoderm4.77e-09203
hindlimb bud4.91e-091
soleus muscle4.91e-091
appendage4.91e-091
lower limb segment4.91e-091
multi-limb segment region4.91e-091
hindlimb muscle4.91e-091
hindlimb zeugopod muscle4.91e-091
paired limb/fin4.91e-091
limb4.91e-091
pelvic appendage4.91e-091
limb segment4.91e-091
paired limb/fin segment4.91e-091
limb muscle4.91e-091
pelvic complex muscle4.91e-091
zeugopod4.91e-091
muscle of leg4.91e-091
paired limb/fin bud4.91e-091


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.401049
MA0004.11.93041
MA0006.10.639288
MA0007.10.804807
MA0009.11.3275
MA0014.10.118426
MA0017.10.686276
MA0019.10.990656
MA0024.11.21731
MA0025.11.46617
MA0027.12.95767
MA0028.10.658629
MA0029.11.23771
MA0030.11.22561
MA0031.11.15713
MA0038.10.94098
MA0040.11.24388
MA0041.10.847069
MA0042.10.810843
MA0043.11.32783
MA0046.11.31611
MA0048.10.341392
MA0050.10.81185
MA0051.10.936307
MA0052.11.24796
MA0055.10.190716
MA0056.10
MA0057.10.333427
MA0058.10.716037
MA0059.10.714521
MA0060.10.492218
MA0061.10.456531
MA0063.10
MA0066.10.941452
MA0067.11.65513
MA0068.10.405474
MA0069.11.31207
MA0070.11.30033
MA0071.10.897953
MA0072.11.29561
MA0073.10.0185922
MA0074.10.935474
MA0076.10.734647
MA0077.11.28751
MA0078.11.04495
MA0081.10.714712
MA0083.11.33535
MA0084.11.84562
MA0087.11.29304
MA0088.10.257905
MA0089.10
MA0090.10.751469
MA0091.10.829044
MA0092.10.785956
MA0093.11.55117
MA0095.10
MA0098.10
MA0100.10.956299
MA0101.10.646932
MA0103.10.628063
MA0105.12.3269
MA0106.10.986396
MA0107.10.556367
MA0108.21.15387
MA0109.10
MA0111.10.767139
MA0113.11.00436
MA0114.10.549955
MA0115.11.57693
MA0116.12.36034
MA0117.11.36676
MA0119.10.695578
MA0122.11.39371
MA0124.11.53432
MA0125.11.44766
MA0130.10
MA0131.11.06461
MA0132.10
MA0133.10
MA0135.11.35921
MA0136.10.948776
MA0139.10.440097
MA0140.10.894983
MA0141.10.712476
MA0142.11.12317
MA0143.11.00455
MA0144.10.531867
MA0145.10.273764
MA0146.10.107247
MA0147.11.38767
MA0148.10.854239
MA0149.10.884158
MA0062.21.141
MA0035.20.894194
MA0039.20.0526989
MA0138.21.04628
MA0002.20.476938
MA0137.20.666381
MA0104.21.2307
MA0047.20.973066
MA0112.20.264678
MA0065.20.277623
MA0150.10.744617
MA0151.10
MA0152.10.902317
MA0153.11.43021
MA0154.11.51687
MA0155.10.256269
MA0156.10.669101
MA0157.11.09377
MA0158.10
MA0159.10.565904
MA0160.10.871361
MA0161.10
MA0162.10.149099
MA0163.10.387745
MA0164.11.01792
MA0080.20.643061
MA0018.20.987913
MA0099.20.902716
MA0079.20.09178
MA0102.21.88331
MA0258.10.519674
MA0259.11.40979
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.