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Coexpression cluster:C1806

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Full id: C1806_acute_mesothelioma_small_neuroblastoma_Astrocyte_hepatoma_gastrointestinal



Phase1 CAGE Peaks

Hg19::chr18:907515..907538,+p@chr18:907515..907538
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Hg19::chr18:907556..907570,+p@chr18:907556..907570
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Hg19::chr18:907582..907595,+p@chr18:907582..907595
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Hg19::chr18:907687..907707,+p@chr18:907687..907707
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Hg19::chr18:907781..907800,+p@chr18:907781..907800
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of nervous system2.14e-2753
regional part of brain2.14e-2753
neural tube1.38e-2556
neural rod1.38e-2556
future spinal cord1.38e-2556
neural keel1.38e-2556
nervous system1.04e-2289
central nervous system3.89e-2281
neural plate4.37e-2082
presumptive neural plate4.37e-2082
brain1.48e-1968
future brain1.48e-1968
neurectoderm8.16e-1986
ecto-epithelium4.64e-17104
regional part of forebrain2.72e-1641
forebrain2.72e-1641
anterior neural tube2.72e-1641
future forebrain2.72e-1641
structure with developmental contribution from neural crest5.26e-14132
segmental subdivision of hindbrain5.95e-1412
hindbrain5.95e-1412
presumptive hindbrain5.95e-1412
pre-chordal neural plate7.42e-1461
telencephalon8.99e-1434
brain grey matter1.10e-1334
gray matter1.10e-1334
cerebral hemisphere7.11e-1332
segmental subdivision of nervous system9.06e-1313
ectoderm-derived structure1.56e-12171
ectoderm1.56e-12171
presumptive ectoderm1.56e-12171
regional part of cerebral cortex4.45e-1222
adult organism2.21e-11114
brainstem2.69e-116
neocortex4.02e-1120
regional part of metencephalon5.72e-119
metencephalon5.72e-119
future metencephalon5.72e-119
regional part of telencephalon6.42e-1132
posterior neural tube7.06e-1115
chordal neural plate7.06e-1115
cerebral cortex2.03e-1025
pallium2.03e-1025
pons9.04e-093
organ system subdivision2.67e-08223
gyrus1.85e-076
tube3.28e-07192


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.