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Coexpression cluster:C3312

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Full id: C3312_Endothelial_Renal_Hepatic_heart_umbilical_Lymphatic_adipose



Phase1 CAGE Peaks

Hg19::chr12:6143894..6143914,-p@chr12:6143894..6143914
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Hg19::chr12:6167137..6167153,-p@chr12:6167137..6167153
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Hg19::chr20:62680671..62680679,-p2@SOX18


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism2.00e-47115
endothelium3.70e-2118
blood vessel endothelium3.70e-2118
cardiovascular system endothelium3.70e-2118
anatomical conduit4.75e-21241
anatomical cluster5.40e-19286
simple squamous epithelium3.58e-1622
squamous epithelium5.87e-1525
tube6.96e-14194
endothelial tube1.37e-129
arterial system endothelium1.37e-129
endothelium of artery1.37e-129
vessel1.11e-1069
lymphoid system1.57e-1010
neural tube2.48e-0957
neural rod2.48e-0957
future spinal cord2.48e-0957
neural keel2.48e-0957
lymphatic vessel4.96e-098
lymph vasculature4.96e-098
lymphatic part of lymphoid system4.96e-098
vasculature3.61e-0879
vascular system3.61e-0879
circulatory system6.66e-08113
gray matter6.96e-0834
brain grey matter6.96e-0834
splanchnic layer of lateral plate mesoderm1.09e-0784
multi-cellular organism1.23e-07659
regional part of brain2.76e-0759
epithelium3.06e-07309
anterior neural tube3.37e-0742
regional part of telencephalon3.84e-0733
cell layer5.50e-07312
telencephalon8.33e-0734


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.