Coexpression cluster:C84

Full id: C84_choriocarcinoma_pancreatic_Wilms_Mallassezderived_thymus_salivary_colon

Phase1 CAGE Peaks

Hg19::chr10:104523254..104523259,+	p1@AY656173
Hg19::chr10:180364..180371,+	p22@ZMYND11
Hg19::chr10:180416..180429,+	p9@ZMYND11
Hg19::chr10:43871094..43871105,+	p@chr10:43871094..43871105 +
Hg19::chr10:43871125..43871134,+	p@chr10:43871125..43871134 +
Hg19::chr10:88734366..88734378,-	p@chr10:88734366..88734378 -
Hg19::chr10:98045175..98045180,-	p@chr10:98045175..98045180 -
Hg19::chr11:118829041..118829050,+	p9@UPK2
Hg19::chr11:129719878..129719909,+	p4@TMEM45B
Hg19::chr11:129720358..129720368,+	p3@TMEM45B
Hg19::chr11:129720377..129720381,+	p5@TMEM45B
Hg19::chr11:71900572..71900600,+	p5@FOLR1
Hg19::chr11:71900617..71900626,+	p9@FOLR1
Hg19::chr11:71900651..71900661,+	p7@FOLR1
Hg19::chr11:78075139..78075168,-	p@chr11:78075139..78075168 -
Hg19::chr11:78075190..78075199,-	p@chr11:78075190..78075199 -
Hg19::chr11:78075217..78075237,-	p@chr11:78075217..78075237 -
Hg19::chr12:110114268..110114270,-	p@chr12:110114268..110114270 -
Hg19::chr12:6422294..6422299,+	p3@PLEKHG6
Hg19::chr12:7867067..7867070,+	p@chr12:7867067..7867070 +
Hg19::chr12:8116908..8116910,-	p@chr12:8116908..8116910 -
Hg19::chr12:8123169..8123195,-	p@chr12:8123169..8123195 -
Hg19::chr13:111142867..111142874,+	p@chr13:111142867..111142874 +
Hg19::chr13:114188109..114188155,+	p@chr13:114188109..114188155 +
Hg19::chr13:44770203..44770212,+	p@chr13:44770203..44770212 +
Hg19::chr13:52555605..52555624,-	p@chr13:52555605..52555624 -
Hg19::chr13:99607719..99607763,-	p@chr13:99607719..99607763 -
Hg19::chr13:99628257..99628268,-	p@chr13:99628257..99628268 -
Hg19::chr14:23284322..23284345,+	p@chr14:23284322..23284345 +
Hg19::chr14:24732838..24732850,-	p8@TGM1
Hg19::chr14:35120236..35120240,-	p@chr14:35120236..35120240 -
Hg19::chr14:65703391..65703398,-	p@chr14:65703391..65703398 -
Hg19::chr14:69212445..69212449,-	p@chr14:69212445..69212449 -
Hg19::chr14:96912885..96912895,+	p@chr14:96912885..96912895 +
Hg19::chr14:99927301..99927311,-	p@chr14:99927301..99927311 -
Hg19::chr14:99936479..99936482,-	p@chr14:99936479..99936482 -
Hg19::chr14:99941657..99941686,-	p@chr14:99941657..99941686 -
Hg19::chr15:21145765..21145768,+	p1@LOC348120
Hg19::chr15:47631257..47631269,+	p12@SEMA6D
Hg19::chr15:47631272..47631287,+	p5@SEMA6D
Hg19::chr15:47660175..47660177,+	p@chr15:47660175..47660177 +
Hg19::chr15:47677042..47677046,+	p@chr15:47677042..47677046 +
Hg19::chr15:47677260..47677265,+	p@chr15:47677260..47677265 +
Hg19::chr15:47772172..47772194,+	p@chr15:47772172..47772194 +
Hg19::chr15:47826399..47826406,+	p@chr15:47826399..47826406 +
Hg19::chr15:47827194..47827198,+	p@chr15:47827194..47827198 +
Hg19::chr15:47879103..47879107,+	p@chr15:47879103..47879107 +
Hg19::chr15:47894707..47894712,+	p@chr15:47894707..47894712 +
Hg19::chr15:47894742..47894745,+	p@chr15:47894742..47894745 +
Hg19::chr15:47902739..47902751,+	p@chr15:47902739..47902751 +
Hg19::chr15:47904977..47904980,+	p@chr15:47904977..47904980 +
Hg19::chr15:58793414..58793417,-	p@chr15:58793414..58793417 -
Hg19::chr15:63124822..63124829,+	p@chr15:63124822..63124829 +
Hg19::chr15:63124864..63124869,+	p@chr15:63124864..63124869 +
Hg19::chr15:72460468..72460473,-	p@chr15:72460468..72460473 -
Hg19::chr15:72462800..72462811,-	p@chr15:72462800..72462811 -
Hg19::chr15:90956928..90956977,+	p@chr15:90956928..90956977 +
Hg19::chr16:57945787..57945794,-	p@chr16:57945787..57945794 -
Hg19::chr16:57945799..57945809,-	p@chr16:57945799..57945809 -
Hg19::chr16:81105625..81105648,+	p@chr16:81105625..81105648 +
Hg19::chr16:81105657..81105669,+	p@chr16:81105657..81105669 +
Hg19::chr16:87885491..87885503,-	p@chr16:87885491..87885503 -
Hg19::chr16:88831461..88831505,-	p@chr16:88831461..88831505 -
Hg19::chr17:25568727..25568737,-	p@chr17:25568727..25568737 -
Hg19::chr17:29815086..29815095,+	p7@RAB11FIP4
Hg19::chr17:45928798..45928824,+	p@chr17:45928798..45928824 +
Hg19::chr17:47979460..47979473,+	p@chr17:47979460..47979473 +
Hg19::chr17:64413661..64413687,+	p@chr17:64413661..64413687 +
Hg19::chr17:72749237..72749249,+	p@chr17:72749237..72749249 +
Hg19::chr17:79166343..79166352,-	p@chr17:79166343..79166352 -
Hg19::chr17:79166374..79166392,-	p@chr17:79166374..79166392 -
Hg19::chr17:79166560..79166583,+	p@chr17:79166560..79166583 +
Hg19::chr18:11880823..11880832,+	p@chr18:11880823..11880832 +
Hg19::chr18:11880835..11880850,+	p@chr18:11880835..11880850 +
Hg19::chr18:57376516..57376545,+	p@chr18:57376516..57376545 +
Hg19::chr18:60755714..60755742,+	p@chr18:60755714..60755742 +
Hg19::chr18:6683324..6683360,+	p@chr18:6683324..6683360 +
Hg19::chr18:6683365..6683372,+	p@chr18:6683365..6683372 +
Hg19::chr18:6683373..6683396,+	p@chr18:6683373..6683396 +
Hg19::chr18:6683397..6683410,+	p@chr18:6683397..6683410 +
Hg19::chr19:17422893..17422904,+	p@chr19:17422893..17422904 +
Hg19::chr19:38827799..38827808,+	p9@CATSPERG
Hg19::chr19:39314362..39314374,-	p@chr19:39314362..39314374 -
Hg19::chr19:39728474..39728484,-	p@chr19:39728474..39728484 -
Hg19::chr19:39799144..39799167,-	p@chr19:39799144..39799167 -
Hg19::chr19:40128244..40128250,+	p@chr19:40128244..40128250 +
Hg19::chr19:40146547..40146563,+	p1@LGALS16
Hg19::chr19:40146564..40146569,+	p2@LGALS16
Hg19::chr19:41318010..41318016,-	p@chr19:41318010..41318016 -
Hg19::chr19:51021842..51021852,-	p14@LRRC4B
Hg19::chr19:53554417..53554419,+	p@chr19:53554417..53554419 +
Hg19::chr19:54158391..54158393,+	p@chr19:54158391..54158393 +
Hg19::chr19:7854634..7854677,+	p@chr19:7854634..7854677 +
Hg19::chr1:116260596..116260605,-	p@chr1:116260596..116260605 -
Hg19::chr1:116915085..116915100,+	p47@ATP1A1
Hg19::chr1:12030696..12030711,+	p@chr1:12030696..12030711 +
Hg19::chr1:16894621..16894652,-	p@chr1:16894621..16894652 -
Hg19::chr1:175337138..175337139,-	p@chr1:175337138..175337139 -
Hg19::chr1:204426293..204426304,-	p@chr1:204426293..204426304 -
Hg19::chr1:228917012..228917024,-	p@chr1:228917012..228917024 -
Hg19::chr1:24927262..24927267,+	p@chr1:24927262..24927267 +
Hg19::chr1:24927317..24927324,+	p@chr1:24927317..24927324 +
Hg19::chr1:24927340..24927347,+	p@chr1:24927340..24927347 +
Hg19::chr1:24927360..24927363,+	p@chr1:24927360..24927363 +
Hg19::chr1:24927416..24927423,+	p@chr1:24927416..24927423 +
Hg19::chr1:25246232..25246236,+	p@chr1:25246232..25246236 +
Hg19::chr1:54356404..54356408,-	p5@YIPF1
Hg19::chr1:57035544..57035561,-	p@chr1:57035544..57035561 -
Hg19::chr1:95318801..95318810,+	p@chr1:95318801..95318810 +
Hg19::chr20:42780517..42780522,+	p@chr20:42780517..42780522 +
Hg19::chr20:42780550..42780563,+	p@chr20:42780550..42780563 +
Hg19::chr20:42780570..42780577,+	p@chr20:42780570..42780577 +
Hg19::chr20:48864193..48864206,-	p@chr20:48864193..48864206 -
Hg19::chr20:55154489..55154499,+	p@chr20:55154489..55154499 +
Hg19::chr20:55154504..55154509,+	p@chr20:55154504..55154509 +
Hg19::chr20:55154517..55154524,+	p@chr20:55154517..55154524 +
Hg19::chr20:57444099..57444121,+	p@chr20:57444099..57444121 +
Hg19::chr21:40693544..40693556,-	p12@BRWD1
Hg19::chr21:44027711..44027715,-	p@chr21:44027711..44027715 -
Hg19::chr22:21386843..21386862,-	p1@SLC7A4
Hg19::chr22:21387127..21387141,-	p3@SLC7A4
Hg19::chr22:21387144..21387157,-	p2@SLC7A4
Hg19::chr22:21387219..21387231,-	p5@SLC7A4
Hg19::chr22:36677325..36677328,+	p@chr22:36677325..36677328 +
Hg19::chr22:37593734..37593766,-	p6@C1QTNF6
Hg19::chr2:106468611..106468642,+	p@chr2:106468611..106468642 +
Hg19::chr2:24585157..24585182,-	p@chr2:24585157..24585182 -
Hg19::chr2:63842411..63842435,+	p@chr2:63842411..63842435 +
Hg19::chr2:64073187..64073217,+	p7@UGP2
Hg19::chr2:64073244..64073249,+	p20@UGP2
Hg19::chr2:83744957..83744980,-	p@chr2:83744957..83744980 -
Hg19::chr2:86491426..86491435,-	p@chr2:86491426..86491435 -
Hg19::chr2:86491443..86491453,-	p@chr2:86491443..86491453 -
Hg19::chr2:86491506..86491526,-	p@chr2:86491506..86491526 -
Hg19::chr2:97171335..97171339,-	p4@NEURL3
Hg19::chr3:134070021..134070025,-	p@chr3:134070021..134070025 -
Hg19::chr3:135741866..135741908,+	p7@PPP2R3A
Hg19::chr3:171842808..171842842,+	p@chr3:171842808..171842842 +
Hg19::chr3:17279717..17279732,-	p@chr3:17279717..17279732 -
Hg19::chr3:183685589..183685598,-	p@chr3:183685589..183685598 -
Hg19::chr3:183685654..183685662,-	p@chr3:183685654..183685662 -
Hg19::chr3:32115811..32115821,-	p@chr3:32115811..32115821 -
Hg19::chr3:42194174..42194205,+	p@chr3:42194174..42194205 +
Hg19::chr3:42907686..42907687,+	p@chr3:42907686..42907687 +
Hg19::chr3:61598117..61598119,+	p@chr3:61598117..61598119 +
Hg19::chr4:111397140..111397177,+	p5@ENPEP
Hg19::chr4:141686304..141686315,+	p@chr4:141686304..141686315 +
Hg19::chr4:183164548..183164562,+	p4@ODZ3
Hg19::chr4:53617129..53617135,+	p@chr4:53617129..53617135 +
Hg19::chr4:89080129..89080138,-	p16@ABCG2
Hg19::chr4:89080205..89080219,-	p5@ABCG2
Hg19::chr4:89080362..89080367,-	p25@ABCG2
Hg19::chr4:89574768..89574807,+	p@chr4:89574768..89574807 +
Hg19::chr5:122079128..122079137,-	p@chr5:122079128..122079137 -
Hg19::chr5:122079143..122079157,-	p@chr5:122079143..122079157 -
Hg19::chr5:131329923..131329950,-	p16@ACSL6
Hg19::chr5:167709436..167709444,+	p@chr5:167709436..167709444 +
Hg19::chr5:17664162..17664181,+	p@chr5:17664162..17664181 +
Hg19::chr5:1882634..1882643,-	p@chr5:1882634..1882643 -
Hg19::chr5:5447673..5447685,+	p@chr5:5447673..5447685 +
Hg19::chr6:10419884..10419898,-	p11@TFAP2A
Hg19::chr6:111598263..111598273,+	p@chr6:111598263..111598273 +
Hg19::chr6:111598285..111598299,+	p@chr6:111598285..111598299 +
Hg19::chr6:111598307..111598326,+	p@chr6:111598307..111598326 +
Hg19::chr6:111599825..111599830,+	p@chr6:111599825..111599830 +
Hg19::chr6:11243959..11243976,-	p@chr6:11243959..11243976 -
Hg19::chr6:159246887..159246895,+	p@chr6:159246887..159246895 +
Hg19::chr6:159246910..159246927,+	p@chr6:159246910..159246927 +
Hg19::chr6:164092689..164092695,+	p3@uc003quk.1
Hg19::chr6:168813785..168813789,-	p@chr6:168813785..168813789 -
Hg19::chr6:32534818..32534824,-	p@chr6:32534818..32534824 -
Hg19::chr6:32534836..32534846,-	p@chr6:32534836..32534846 -
Hg19::chr6:32534847..32534859,-	p@chr6:32534847..32534859 -
Hg19::chr6:52876815..52876822,-	p@chr6:52876815..52876822 -
Hg19::chr6:8158396..8158426,+	p@chr6:8158396..8158426 +
Hg19::chr6:8358321..8358327,+	p@chr6:8358321..8358327 +
Hg19::chr7:100454665..100454679,+	p11@SLC12A9
Hg19::chr7:107621426..107621437,-	p@chr7:107621426..107621437 -
Hg19::chr7:138349562..138349572,-	p@chr7:138349562..138349572 -
Hg19::chr7:151772066..151772079,+	p10@GALNT11
Hg19::chr7:151772140..151772147,+	p14@GALNT11
Hg19::chr7:23504984..23505015,-	p@chr7:23504984..23505015 -
Hg19::chr7:26122940..26122948,-	p@chr7:26122940..26122948 -
Hg19::chr7:26122989..26122995,-	p@chr7:26122989..26122995 -
Hg19::chr7:29152388..29152434,-	p2@CPVL
Hg19::chr7:29152444..29152447,-	p18@CPVL
Hg19::chr7:30389015..30389032,+	p@chr7:30389015..30389032 +
Hg19::chr7:30389043..30389058,+	p@chr7:30389043..30389058 +
Hg19::chr7:37532185..37532188,+	p@chr7:37532185..37532188 +
Hg19::chr7:48494678..48494690,+	p2@ABCA13
Hg19::chr7:48494711..48494722,+	p3@ABCA13
Hg19::chr7:48494733..48494742,+	p4@ABCA13
Hg19::chr7:64407700..64407712,+	p@chr7:64407700..64407712 +
Hg19::chr7:99711960..99711971,-	p14@TAF6
Hg19::chr7:99711987..99711992,-	p16@TAF6
Hg19::chr8:102062552..102062564,+	p@chr8:102062552..102062564 +
Hg19::chr8:102062574..102062582,+	p@chr8:102062574..102062582 +
Hg19::chr8:135870427..135870454,+	p@chr8:135870427..135870454 +
Hg19::chr8:136103083..136103088,+	p@chr8:136103083..136103088 +
Hg19::chr8:142350638..142350683,+	p1@LOC731779
Hg19::chr8:143834403..143834444,-	p4@LYPD2
Hg19::chr8:144073030..144073072,+	p@chr8:144073030..144073072 +
Hg19::chr8:22844858..22844865,+	p27@RHOBTB2
Hg19::chr8:22844879..22844887,+	p29@RHOBTB2
Hg19::chr8:22844913..22844935,+	p13@RHOBTB2
Hg19::chr8:23313628..23313641,-	p@chr8:23313628..23313641 -
Hg19::chr9:34484972..34484978,+	p8@DNAI1
Hg19::chr9:4419394..4419412,-	p@chr9:4419394..4419412 -
Hg19::chr9:4620436..4620441,-	p@chr9:4620436..4620441 -
Hg19::chr9:4620442..4620450,-	p@chr9:4620442..4620450 -
Hg19::chr9:99801414..99801432,-	p1@CTSL2
Hg19::chrX:112083176..112083179,-	p@chrX:112083176..112083179 -
Hg19::chrX:148769849..148769864,+	p2@MAGEA11
Hg19::chrX:148769880..148769885,+	p5@MAGEA11
Hg19::chrX:49819072..49819078,+	p@chrX:49819072..49819078 +
Hg19::chrX:51577402..51577404,+	p@chrX:51577402..51577404 +
Hg19::chrX:51577449..51577463,+	p@chrX:51577449..51577463 +
Hg19::chrX:70319128..70319142,+	p3@FOXO4
Hg19::chrY:9195450..9195471,+	p1@TSPY4 p1@TSPY8

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

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No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n
epithelial cell	8.23e-22	254
endo-epithelial cell	2.20e-08	43
endodermal cell	4.13e-08	59

Uber Anatomy

Ontology term	p-value	n
organ	8.83e-15	511
ectoderm	3.05e-13	173
presumptive ectoderm	3.05e-13	173
ectoderm-derived structure	4.14e-13	169
regional part of nervous system	8.13e-13	94
nervous system	8.13e-13	94
central nervous system	3.64e-12	82
endoderm-derived structure	3.03e-10	169
endoderm	3.03e-10	169
presumptive endoderm	3.03e-10	169
adult organism	6.20e-10	115
embryo	1.21e-09	612
brain	2.28e-09	69
future brain	2.28e-09	69
organ part	7.91e-09	219
neural tube	1.44e-08	57
neural rod	1.44e-08	57
future spinal cord	1.44e-08	57
neural keel	1.44e-08	57
multi-cellular organism	1.53e-08	659
anterior region of body	2.14e-08	129
craniocervical region	2.14e-08	129
subdivision of digestive tract	2.14e-08	129
endodermal part of digestive tract	2.14e-08	129
digestive system	2.17e-08	155
digestive tract	2.17e-08	155
primitive gut	2.17e-08	155
head	4.07e-08	123
mixed endoderm/mesoderm-derived structure	4.61e-08	130
embryonic structure	9.16e-08	605
developing anatomical structure	9.16e-08	605
germ layer	1.47e-07	604
embryonic tissue	1.47e-07	604
presumptive structure	1.47e-07	604
epiblast (generic)	1.47e-07	604
regional part of brain	1.96e-07	59
neurectoderm	2.04e-07	90
neural plate	2.47e-07	86
presumptive neural plate	2.47e-07	86
foregut	4.51e-07	98
endo-epithelium	4.60e-07	82
anterior neural tube	7.45e-07	42
regional part of forebrain	9.45e-07	41
forebrain	9.45e-07	41
future forebrain	9.45e-07	41

Disease

Ontology term	p-value	n
carcinoma	4.75e-25	106
cell type cancer	1.25e-23	143
cancer	3.27e-12	235
disease of cellular proliferation	3.19e-11	239

Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}

ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

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(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF	#promoters	Enrichment	p-value	q-value
GATA3#2625	29	3.60666198337431	3.03431973552081e-09	2.54130969413037e-07
TAL1#6886	17	2.31856841788349	0.00124624487515101	0.00837989753514658

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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