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MCL coexpression mm9:287: Difference between revisions

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|ontology_enrichment_uberon=UBERON:0000073!2.49e-39!54;UBERON:0001049!1.98e-36!52;UBERON:0005068!1.98e-36!52;UBERON:0006241!1.98e-36!52;UBERON:0007135!1.98e-36!52;UBERON:0002346!9.42e-35!64;UBERON:0003075!9.42e-35!64;UBERON:0007284!9.42e-35!64;UBERON:0001017!5.03e-34!73;UBERON:0001016!1.04e-32!75;UBERON:0000955!1.68e-29!47;UBERON:0006238!1.68e-29!47;UBERON:0002020!6.16e-29!34;UBERON:0010371!1.12e-28!73;UBERON:0004121!1.20e-28!95;UBERON:0000924!1.20e-28!95;UBERON:0006601!1.20e-28!95;UBERON:0002616!2.65e-28!46;UBERON:0003056!2.97e-26!49;UBERON:0003080!1.49e-25!40;UBERON:0002780!2.63e-24!39;UBERON:0001890!2.63e-24!39;UBERON:0006240!2.63e-24!39;UBERON:0003528!3.72e-22!29;UBERON:0002791!3.72e-22!29;UBERON:0001893!3.72e-22!29;UBERON:0010314!8.15e-20!92;UBERON:0000956!3.34e-13!21;UBERON:0001869!3.34e-13!21;UBERON:0000203!3.34e-13!21;UBERON:0002021!5.37e-12!10;UBERON:0000411!5.37e-12!10;UBERON:0001950!5.37e-12!10;UBERON:0002619!9.00e-12!17;UBERON:0003076!5.22e-11!12;UBERON:0003057!5.22e-11!12;UBERON:0002420!1.18e-10!8;UBERON:0007245!1.18e-10!8;UBERON:0010009!1.18e-10!8;UBERON:0010011!1.18e-10!8;UBERON:0000454!1.18e-10!8;UBERON:0000025!1.09e-09!114;UBERON:0002240!1.72e-09!6;UBERON:0005174!1.72e-09!6;UBERON:0001137!1.72e-09!6;UBERON:0004111!2.66e-08!122;UBERON:0001948!2.84e-08!5;UBERON:0002315!2.84e-08!5;UBERON:0002950!7.59e-07!4;UBERON:0001891!7.59e-07!4;UBERON:0009616!7.59e-07!4;UBERON:0010286!7.59e-07!4
|ontology_enrichment_uberon=UBERON:0000073!2.49e-39!54;UBERON:0001049!1.98e-36!52;UBERON:0005068!1.98e-36!52;UBERON:0006241!1.98e-36!52;UBERON:0007135!1.98e-36!52;UBERON:0002346!9.42e-35!64;UBERON:0003075!9.42e-35!64;UBERON:0007284!9.42e-35!64;UBERON:0001017!5.03e-34!73;UBERON:0001016!1.04e-32!75;UBERON:0000955!1.68e-29!47;UBERON:0006238!1.68e-29!47;UBERON:0002020!6.16e-29!34;UBERON:0010371!1.12e-28!73;UBERON:0004121!1.20e-28!95;UBERON:0000924!1.20e-28!95;UBERON:0006601!1.20e-28!95;UBERON:0002616!2.65e-28!46;UBERON:0003056!2.97e-26!49;UBERON:0003080!1.49e-25!40;UBERON:0002780!2.63e-24!39;UBERON:0001890!2.63e-24!39;UBERON:0006240!2.63e-24!39;UBERON:0003528!3.72e-22!29;UBERON:0002791!3.72e-22!29;UBERON:0001893!3.72e-22!29;UBERON:0010314!8.15e-20!92;UBERON:0000956!3.34e-13!21;UBERON:0001869!3.34e-13!21;UBERON:0000203!3.34e-13!21;UBERON:0002021!5.37e-12!10;UBERON:0000411!5.37e-12!10;UBERON:0001950!5.37e-12!10;UBERON:0002619!9.00e-12!17;UBERON:0003076!5.22e-11!12;UBERON:0003057!5.22e-11!12;UBERON:0002420!1.18e-10!8;UBERON:0007245!1.18e-10!8;UBERON:0010009!1.18e-10!8;UBERON:0010011!1.18e-10!8;UBERON:0000454!1.18e-10!8;UBERON:0000025!1.09e-09!114;UBERON:0002240!1.72e-09!6;UBERON:0005174!1.72e-09!6;UBERON:0001137!1.72e-09!6;UBERON:0004111!2.66e-08!122;UBERON:0001948!2.84e-08!5;UBERON:0002315!2.84e-08!5;UBERON:0002950!7.59e-07!4;UBERON:0001891!7.59e-07!4;UBERON:0009616!7.59e-07!4;UBERON:0010286!7.59e-07!4
|tfbs_overrepresentation_for_novel_motifs=0.536504,1.88777,0.220186,0.305194,0.105881,0.324459,0.148388,0.423532,0.0456397,0.471978,0.38953,0.435892,0.242781,0.472235,0.288144,0,0.288299,0.462025,0.0982406,0.383901,0.0473293,0.0693426,0.155233,0.0244851,0.229078,0.514394,1.10643,0.353106,0.14763,0.377483,0.101869,0.367297,0.738145,0.157123,0.289024,0.018278,0.225428,0.430558,0.0159813,0.300831,0.102492,0.340818,0.442687,0.122302,0.723503,0.290621,0.230231,0.117576,0.64161,0.625994,0.27523,0.190239,0.208624,0.485586,0.500658,0.483088,0.159565,0.417144,0.00461258,0.479984,0.351242,0.571459,0.496788,0.266898,0.167068,0.80545,0.621417,0.947606,0.347523,0.807939,0.439167,0.443501,1.53861,0.529888,1.31388,0.657384,0.696947,0.632797,0.337634,0.0488158,0.0443708,0.815104,0.195512,0.107931,0.430864,3.31044,1.91667,0.015138,0.233678,1.10402,0.684894,0.435043,0.984712,0.501015,0.36203,0.0592604,0.415328,0.989725,0.23041,0.464797,0.0203943,0.367072,0.470627,0.275672,0.274889,0.10429,0.857465,0.115402,0.188807,0.716259,0.52086,0.472153,0.413098,0.791911,0.691366,0.101001,0.861133,1.5806,0.28928,0.219349,0.534627,0.251614,0.174046,0.631319,0.741383,0.340552,0.153289,0.972632,0.620047,0.509539,0.456151,0.295631,1.4474,0.503994,0.711262,0.900678,0.0756323,0.105244,0.6661,1.46501,1.07314,0.625675,0.181758,0.375761,0.270089,0.104751,0.656561,1.42588,0.0766814,0.261542,0.387255,2.59374,0.486938,0.559278,1.54465,0.558342,0.1909,0.567187,0.531033,0.941491,0.674799,0.430147,0.340904,0.515877,0.738132,0.163443,0.697175,0.140344,0.672203
|tfbs_overrepresentation_for_novel_motifs=0.536504,1.88777,0.220186,0.305194,0.105881,0.324459,0.148388,0.423532,0.0456397,0.471978,0.38953,0.435892,0.242781,0.472235,0.288144,0,0.288299,0.462025,0.0982406,0.383901,0.0473293,0.0693426,0.155233,0.0244851,0.229078,0.514394,1.10643,0.353106,0.14763,0.377483,0.101869,0.367297,0.738145,0.157123,0.289024,0.018278,0.225428,0.430558,0.0159813,0.300831,0.102492,0.340818,0.442687,0.122302,0.723503,0.290621,0.230231,0.117576,0.64161,0.625994,0.27523,0.190239,0.208624,0.485586,0.500658,0.483088,0.159565,0.417144,0.00461258,0.479984,0.351242,0.571459,0.496788,0.266898,0.167068,0.80545,0.621417,0.947606,0.347523,0.807939,0.439167,0.443501,1.53861,0.529888,1.31388,0.657384,0.696947,0.632797,0.337634,0.0488158,0.0443708,0.815104,0.195512,0.107931,0.430864,3.31044,1.91667,0.015138,0.233678,1.10402,0.684894,0.435043,0.984712,0.501015,0.36203,0.0592604,0.415328,0.989725,0.23041,0.464797,0.0203943,0.367072,0.470627,0.275672,0.274889,0.10429,0.857465,0.115402,0.188807,0.716259,0.52086,0.472153,0.413098,0.791911,0.691366,0.101001,0.861133,1.5806,0.28928,0.219349,0.534627,0.251614,0.174046,0.631319,0.741383,0.340552,0.153289,0.972632,0.620047,0.509539,0.456151,0.295631,1.4474,0.503994,0.711262,0.900678,0.0756323,0.105244,0.6661,1.46501,1.07314,0.625675,0.181758,0.375761,0.270089,0.104751,0.656561,1.42588,0.0766814,0.261542,0.387255,2.59374,0.486938,0.559278,1.54465,0.558342,0.1909,0.567187,0.531033,0.941491,0.674799,0.430147,0.340904,0.515877,0.738132,0.163443,0.697175,0.140344,0.672203
|tfbs_overrepresentation_jaspar=MA0003.1;3.43156,MA0004.1;0.305832,MA0006.1;1.20095,MA0007.1;0.084375,MA0009.1;0.388771,MA0014.1;3.08692,MA0017.1;0.141194,MA0019.1;0.248074,MA0024.1;0.353393,MA0025.1;1.43891,MA0027.1;1.95996,MA0028.1;0.12595,MA0029.1;0.336166,MA0030.1;0.341346,MA0031.1;0.84229,MA0038.1;0.17284,MA0040.1;0.399043,MA0041.1;0.464369,MA0042.1;0.0533455,MA0043.1;0.469769,MA0046.1;0.418434,MA0048.1;0.67799,MA0050.1;0.111159,MA0051.1;0.178537,MA0052.1;0.405693,MA0055.1;0.378635,MA0056.1;0,MA0057.1;0.830691,MA0058.1;0.189695,MA0059.1;0.203408,MA0060.1;0.0114726,MA0061.1;0.380864,MA0063.1;0,MA0066.1;0.165937,MA0067.1;0.690195,MA0068.1;2.96294,MA0069.1;0.405974,MA0070.1;0.397975,MA0071.1;0.357212,MA0072.1;0.391015,MA0073.1;2.55311,MA0074.1;0.443199,MA0076.1;0.0413193,MA0077.1;0.373365,MA0078.1;0.200156,MA0081.1;0.0645216,MA0083.1;1.18326,MA0084.1;0.999346,MA0087.1;0.432564,MA0088.1;1.80197,MA0089.1;0,MA0090.1;0.942377,MA0091.1;0.32331,MA0092.1;0.555994,MA0093.1;0.314468,MA0095.1;0,MA0098.1;0,MA0100.1;0.137416,MA0101.1;0.0588523,MA0103.1;0.350053,MA0105.1;0.672153,MA0106.1;0.592733,MA0107.1;0.338168,MA0108.2;0.264668,MA0109.1;0,MA0111.1;0.27977,MA0113.1;0.186674,MA0114.1;0.0743624,MA0115.1;0.472164,MA0116.1;0.279815,MA0117.1;0.44472,MA0119.1;0.059082,MA0122.1;0.461557,MA0124.1;0.641584,MA0125.1;0.574947,MA0130.1;0,MA0131.1;0.685442,MA0132.1;0,MA0133.1;0,MA0135.1;0.501131,MA0136.1;0.156089,MA0139.1;0.92028,MA0140.1;0.13735,MA0141.1;1.06715,MA0142.1;0.817195,MA0143.1;0.573785,MA0144.1;0.0765684,MA0145.1;0.087554,MA0146.1;0.392056,MA0147.1;1.00524,MA0148.1;0.327464,MA0149.1;0.220008,MA0062.2;0.00387198,MA0035.2;0.432878,MA0039.2;0.224742,MA0138.2;2.716,MA0002.2;0.114411,MA0137.2;0.0441189,MA0104.2;1.3763,MA0047.2;0.987855,MA0112.2;1.31116,MA0065.2;0.273313,MA0150.1;0.286158,MA0151.1;0,MA0152.1;0.172422,MA0153.1;0.515592,MA0154.1;0.459593,MA0155.1;1.1957,MA0156.1;0.0410387,MA0157.1;0.762276,MA0158.1;0,MA0159.1;1.05755,MA0160.1;0.331527,MA0161.1;0,MA0162.1;0.824796,MA0163.1;1.34258,MA0164.1;0.15631,MA0080.2;0.146586,MA0018.2;0.488272,MA0099.2;0.234689,MA0079.2;2.90175,MA0102.2;1.04989,MA0258.1;0.570617,MA0259.1;0.386929,MA0442.1;0
}}
}}

Revision as of 11:30, 23 January 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:34020647..34020664,+p@chr10:34020647..34020664
+
Mm9::chr11:33743405..33743416,-p5@Kcnip1
Mm9::chr14:67423733..67423743,-p@chr14:67423733..67423743
-
Mm9::chr14:76956449..76956460,-p4@Serp2
Mm9::chr15:78549275..78549309,-p5@Elfn2
Mm9::chr17:24625616..24625627,+p5@Caskin1
Mm9::chr19:47327907..47327937,+p@chr19:47327907..47327937
+
Mm9::chr1:33964544..33964555,-p3@Bend6
Mm9::chr2:124962334..124962359,+p1@Ctxn2
Mm9::chr2:124962484..124962505,+p2@Ctxn2
Mm9::chr2:181041454..181041465,+p@chr2:181041454..181041465
+
Mm9::chr3:88552800..88552811,-p@chr3:88552800..88552811
-
Mm9::chr4:117521906..117521913,+p15@Slc6a9
Mm9::chr5:137729501..137729520,+p1@Ache
Mm9::chr6:114081223..114081240,+p1@Slc6a11
Mm9::chr6:114198039..114198052,+p@chr6:114198039..114198052
+
Mm9::chr6:114198085..114198112,+p@chr6:114198085..114198112
+
Mm9::chr6:114198155..114198168,+p@chr6:114198155..114198168
+
Mm9::chr6:114198339..114198355,+p@chr6:114198339..114198355
+
Mm9::chr6:114198370..114198396,+p@chr6:114198370..114198396
+
Mm9::chr6:91107077..91107093,+p6@Hdac11
Mm9::chr6:91793870..91793909,-p@chr6:91793870..91793909
-
Mm9::chr7:136400541..136400570,+p1@Ppapdc1a
Mm9::chr7:26460119..26460206,-p1@Tmem91
Mm9::chr7:53125597..53125608,-p@chr7:53125597..53125608
-
Mm9::chr7:58877497..58877512,+p3@Slc17a6
Mm9::chr8:33760116..33760119,-p@chr8:33760116..33760119
-
Mm9::chr8:81334120..81334134,-p6@Lsm6
Mm9::chrX:61750178..61750185,+p@chrX:61750178..61750185
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006836neurotransmitter transport0.000487893433099392
GO:0005283sodium:amino acid symporter activity0.000487893433099392
GO:0005342organic acid transmembrane transporter activity0.000487893433099392
GO:0005416cation:amino acid symporter activity0.000793169376948295
GO:0005328neurotransmitter:sodium symporter activity0.00238250463219786
GO:0005343organic acid:sodium symporter activity0.00238250463219786
GO:0005326neurotransmitter transporter activity0.00238250463219786
GO:0015179L-amino acid transmembrane transporter activity0.00277289081461163
GO:0005275amine transmembrane transporter activity0.00544349046617558
GO:0015171amino acid transmembrane transporter activity0.00549769167310049
GO:0015370solute:sodium symporter activity0.00617884339273634
GO:0015294solute:cation symporter activity0.0095865853648283
GO:0046943carboxylic acid transmembrane transporter activity0.00977373582424807
GO:0006581acetylcholine catabolic process0.00977373582424807
GO:0003990acetylcholinesterase activity0.00977373582424807
GO:0022891substrate-specific transmembrane transporter activity0.0124562618492223
GO:0008291acetylcholine metabolic process0.0154275641646028
GO:0032800receptor biosynthetic process0.0154275641646028
GO:0045212neurotransmitter receptor biosynthetic process0.0154275641646028
GO:0001505regulation of neurotransmitter levels0.0163882840827892
GO:0022857transmembrane transporter activity0.016420888300229
GO:0006810transport0.0169058882193297
GO:0051234establishment of localization0.0169058882193297
GO:0001919regulation of receptor recycling0.0169058882193297
GO:0043236laminin binding0.0169058882193297
GO:0005332gamma-aminobutyric acid:sodium symporter activity0.0169058882193297
GO:0022892substrate-specific transporter activity0.0178922045850977
GO:0031623receptor internalization0.0188998132089217
GO:0004104cholinesterase activity0.0188998132089217
GO:0042439ethanolamine and derivative metabolic process0.0188998132089217
GO:0015185L-gamma-aminobutyric acid transmembrane transporter activity0.0188998132089217
GO:0008324cation transmembrane transporter activity0.0200721206149368
GO:0001881receptor recycling0.0217456361305597
GO:0015293symporter activity0.0217456361305597
GO:0051179localization0.0219577964512983
GO:0050840extracellular matrix binding0.0219577964512983
GO:0043621protein self-association0.0219577964512983
GO:0045213neurotransmitter receptor metabolic process0.0219577964512983
GO:0005313L-glutamate transmembrane transporter activity0.0219577964512983
GO:0015172acidic amino acid transmembrane transporter activity0.0219577964512983
GO:0001504neurotransmitter uptake0.0249850850611956
GO:0051262protein tetramerization0.0278661202732491
GO:0015291secondary active transmembrane transporter activity0.0296954910337121
GO:0060041retina development in camera-type eye0.0299153999596034
GO:0042135neurotransmitter catabolic process0.0321993161904013
GO:0007268synaptic transmission0.0321993161904013
GO:0015075ion transmembrane transporter activity0.0323653279984625
GO:0004407histone deacetylase activity0.0357847268869069
GO:0033558protein deacetylase activity0.0357847268869069
GO:0019213deacetylase activity0.0394701876471836
GO:0042402biogenic amine catabolic process0.0394701876471836
GO:0019226transmission of nerve impulse0.0394701876471836
GO:0042219amino acid derivative catabolic process0.0432429813478802
GO:0006898receptor-mediated endocytosis0.0432429813478802



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
regional part of nervous system2.49e-3954
neural tube1.98e-3652
neural rod1.98e-3652
future spinal cord1.98e-3652
neural keel1.98e-3652
neurectoderm9.42e-3564
neural plate9.42e-3564
presumptive neural plate9.42e-3564
central nervous system5.03e-3473
nervous system1.04e-3275
brain1.68e-2947
future brain1.68e-2947
gray matter6.16e-2934
ecto-epithelium1.12e-2873
ectoderm-derived structure1.20e-2895
ectoderm1.20e-2895
presumptive ectoderm1.20e-2895
regional part of brain2.65e-2846
pre-chordal neural plate2.97e-2649
anterior neural tube1.49e-2540
regional part of forebrain2.63e-2439
forebrain2.63e-2439
future forebrain2.63e-2439
brain grey matter3.72e-2229
regional part of telencephalon3.72e-2229
telencephalon3.72e-2229
structure with developmental contribution from neural crest8.15e-2092
cerebral cortex3.34e-1321
cerebral hemisphere3.34e-1321
pallium3.34e-1321
occipital lobe5.37e-1210
visual cortex5.37e-1210
neocortex5.37e-1210
regional part of cerebral cortex9.00e-1217
posterior neural tube5.22e-1112
chordal neural plate5.22e-1112
basal ganglion1.18e-108
nuclear complex of neuraxis1.18e-108
aggregate regional part of brain1.18e-108
collection of basal ganglia1.18e-108
cerebral subcortex1.18e-108
tube1.09e-09114
spinal cord1.72e-096
dorsal region element1.72e-096
dorsum1.72e-096
anatomical conduit2.66e-08122
regional part of spinal cord2.84e-085
gray matter of spinal cord2.84e-085
regional part of midbrain7.59e-074
midbrain7.59e-074
presumptive midbrain7.59e-074
midbrain neural tube7.59e-074


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.13.43156
MA0004.10.305832
MA0006.11.20095
MA0007.10.084375
MA0009.10.388771
MA0014.13.08692
MA0017.10.141194
MA0019.10.248074
MA0024.10.353393
MA0025.11.43891
MA0027.11.95996
MA0028.10.12595
MA0029.10.336166
MA0030.10.341346
MA0031.10.84229
MA0038.10.17284
MA0040.10.399043
MA0041.10.464369
MA0042.10.0533455
MA0043.10.469769
MA0046.10.418434
MA0048.10.67799
MA0050.10.111159
MA0051.10.178537
MA0052.10.405693
MA0055.10.378635
MA0056.10
MA0057.10.830691
MA0058.10.189695
MA0059.10.203408
MA0060.10.0114726
MA0061.10.380864
MA0063.10
MA0066.10.165937
MA0067.10.690195
MA0068.12.96294
MA0069.10.405974
MA0070.10.397975
MA0071.10.357212
MA0072.10.391015
MA0073.12.55311
MA0074.10.443199
MA0076.10.0413193
MA0077.10.373365
MA0078.10.200156
MA0081.10.0645216
MA0083.11.18326
MA0084.10.999346
MA0087.10.432564
MA0088.11.80197
MA0089.10
MA0090.10.942377
MA0091.10.32331
MA0092.10.555994
MA0093.10.314468
MA0095.10
MA0098.10
MA0100.10.137416
MA0101.10.0588523
MA0103.10.350053
MA0105.10.672153
MA0106.10.592733
MA0107.10.338168
MA0108.20.264668
MA0109.10
MA0111.10.27977
MA0113.10.186674
MA0114.10.0743624
MA0115.10.472164
MA0116.10.279815
MA0117.10.44472
MA0119.10.059082
MA0122.10.461557
MA0124.10.641584
MA0125.10.574947
MA0130.10
MA0131.10.685442
MA0132.10
MA0133.10
MA0135.10.501131
MA0136.10.156089
MA0139.10.92028
MA0140.10.13735
MA0141.11.06715
MA0142.10.817195
MA0143.10.573785
MA0144.10.0765684
MA0145.10.087554
MA0146.10.392056
MA0147.11.00524
MA0148.10.327464
MA0149.10.220008
MA0062.20.00387198
MA0035.20.432878
MA0039.20.224742
MA0138.22.716
MA0002.20.114411
MA0137.20.0441189
MA0104.21.3763
MA0047.20.987855
MA0112.21.31116
MA0065.20.273313
MA0150.10.286158
MA0151.10
MA0152.10.172422
MA0153.10.515592
MA0154.10.459593
MA0155.11.1957
MA0156.10.0410387
MA0157.10.762276
MA0158.10
MA0159.11.05755
MA0160.10.331527
MA0161.10
MA0162.10.824796
MA0163.11.34258
MA0164.10.15631
MA0080.20.146586
MA0018.20.488272
MA0099.20.234689
MA0079.22.90175
MA0102.21.04989
MA0258.10.570617
MA0259.10.386929
MA0442.10
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