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MCL coexpression mm9:602

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:4839624..4839635,-p@chr11:4839624..4839635
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Mm9::chr11:4839683..4839697,-p@chr11:4839683..4839697
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Mm9::chr11:4839712..4839727,-p@chr11:4839712..4839727
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Mm9::chr11:4839812..4839821,-p@chr11:4839812..4839821
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Mm9::chr11:4839936..4839944,-p@chr11:4839936..4839944
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Mm9::chr11:4840044..4840053,-p@chr11:4840044..4840053
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Mm9::chr11:4841397..4841408,-p@chr11:4841397..4841408
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Mm9::chr11:4843926..4843937,-p@chr11:4843926..4843937
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Mm9::chr2:103659822..103659827,-p1@ENSMUST00000118421
p1@ENSMUST00000167989
Mm9::chr6:90686750..90686771,-p7@Iqsec1
Mm9::chr6:90686772..90686811,-p2@Iqsec1
Mm9::chrX:53984619..53984648,+p8@Fhl1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0045110intermediate filament bundle assembly0.0135519871096006
GO:0005883neurofilament0.0135519871096006
GO:0060052neurofilament cytoskeleton organization and biogenesis0.0135519871096006
GO:0060053neurofilament cytoskeleton0.0135519871096006
GO:0045109intermediate filament organization0.0135519871096006
GO:0032011ARF protein signal transduction0.0135519871096006
GO:0005086ARF guanyl-nucleotide exchange factor activity0.0135519871096006
GO:0032012regulation of ARF protein signal transduction0.0135519871096006
GO:0045104intermediate filament cytoskeleton organization and biogenesis0.0186107506779222
GO:0045103intermediate filament-based process0.0197022609843965



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)5.28e-1023
neuroblast (sensu Vertebrata)5.28e-1023

Uber Anatomy
Ontology termp-valuen
regional part of nervous system5.52e-3254
neural tube6.12e-2952
neural rod6.12e-2952
future spinal cord6.12e-2952
neural keel6.12e-2952
neurectoderm4.49e-2864
neural plate4.49e-2864
presumptive neural plate4.49e-2864
central nervous system1.32e-2573
nervous system1.26e-2475
ecto-epithelium2.78e-2373
ectoderm-derived structure5.25e-2295
ectoderm5.25e-2295
presumptive ectoderm5.25e-2295
brain7.19e-2247
future brain7.19e-2247
regional part of brain8.32e-2146
gray matter1.40e-1934
pre-chordal neural plate3.98e-1849
structure with developmental contribution from neural crest2.56e-1792
anterior neural tube5.82e-1740
regional part of forebrain9.62e-1639
forebrain9.62e-1639
future forebrain9.62e-1639
posterior neural tube1.53e-1312
chordal neural plate1.53e-1312
brain grey matter3.02e-1329
regional part of telencephalon3.02e-1329
telencephalon3.02e-1329
occipital lobe1.18e-1110
visual cortex1.18e-1110
neocortex1.18e-1110
spinal cord1.19e-106
dorsal region element1.19e-106
dorsum1.19e-106
regional part of spinal cord5.48e-095
gray matter of spinal cord5.48e-095
regional part of cerebral cortex6.76e-0917
cerebral cortex4.31e-0821
cerebral hemisphere4.31e-0821
pallium4.31e-0821
tube4.64e-08114
regional part of midbrain8.47e-084
midbrain8.47e-084
presumptive midbrain8.47e-084
midbrain neural tube8.47e-084
anatomical conduit5.74e-07122
basal ganglion8.05e-078
nuclear complex of neuraxis8.05e-078
aggregate regional part of brain8.05e-078
collection of basal ganglia8.05e-078
cerebral subcortex8.05e-078


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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