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Coexpression cluster:C3780

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Full id: C3780_submaxillary_salivary_small_parotid_duodenum_colon_gall



Phase1 CAGE Peaks

Hg19::chr19:3708338..3708374,+p2@TJP3
Hg19::chr19:3708376..3708393,+p3@TJP3
Hg19::chr19:49199209..49199284,+p1@FUT2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008107galactoside 2-alpha-L-fucosyltransferase activity0.00835945660815558
GO:0031127alpha(1,2)-fucosyltransferase activity0.00835945660815558
GO:0019317fucose catabolic process0.00919445483353814
GO:0042355L-fucose catabolic process0.00919445483353814
GO:0042354L-fucose metabolic process0.00919445483353814
GO:0006004fucose metabolic process0.010447628911207
GO:0008417fucosyltransferase activity0.0107456579977852
GO:0030173integral to Golgi membrane0.031843689414368
GO:0031228intrinsic to Golgi membrane0.032477416739505
GO:0005923tight junction0.0347950932244708
GO:0043296apical junction complex0.0347950932244708
GO:0016327apicolateral plasma membrane0.0347950932244708
GO:0031301integral to organelle membrane0.0347950932244708
GO:0031300intrinsic to organelle membrane0.0347950932244708
GO:0019320hexose catabolic process0.0347950932244708
GO:0046365monosaccharide catabolic process0.0347950932244708
GO:0046164alcohol catabolic process0.0347950932244708
GO:0005911intercellular junction0.0347950932244708
GO:0006486protein amino acid glycosylation0.0347950932244708
GO:0043413biopolymer glycosylation0.0347950932244708
GO:0009101glycoprotein biosynthetic process0.0347950932244708
GO:0044275cellular carbohydrate catabolic process0.0347950932244708
GO:0016052carbohydrate catabolic process0.0347950932244708
GO:0009100glycoprotein metabolic process0.0361155414592229
GO:0019318hexose metabolic process0.0433227771314757
GO:0005996monosaccharide metabolic process0.0433227771314757
GO:0016758transferase activity, transferring hexosyl groups0.0433227771314757



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
epithelial cell9.53e-20254
endodermal cell1.25e-1759
endo-epithelial cell1.69e-1443
epithelial cell of alimentary canal2.10e-0821
respiratory epithelial cell3.48e-0713
epithelial cell of lung8.03e-0719
Uber Anatomy
Ontology termp-valuen
endoderm-derived structure7.47e-34169
endoderm7.47e-34169
presumptive endoderm7.47e-34169
digestive system3.12e-31155
digestive tract3.12e-31155
primitive gut3.12e-31155
subdivision of digestive tract2.17e-30129
endodermal part of digestive tract2.17e-30129
mixed endoderm/mesoderm-derived structure1.38e-25130
foregut3.69e-2298
respiratory system3.08e-1972
adult organism1.37e-17115
immaterial anatomical entity9.88e-17126
endo-epithelium5.45e-1682
organ8.28e-16511
respiratory tract9.74e-1653
multi-tissue structure4.32e-15347
respiratory primordium9.13e-1438
endoderm of foregut9.13e-1438
anatomical space1.66e-13104
embryo9.88e-13612
segment of respiratory tract1.26e-1146
trunk region element1.84e-11107
multi-cellular organism5.81e-11659
primordium9.80e-11168
embryonic structure2.79e-10605
developing anatomical structure2.79e-10605
thoracic cavity element3.95e-1034
thoracic cavity3.95e-1034
germ layer6.72e-10604
embryonic tissue6.72e-10604
presumptive structure6.72e-10604
epiblast (generic)6.72e-10604
thoracic segment organ1.37e-0935
mesenchyme3.08e-09238
entire embryonic mesenchyme3.08e-09238
subdivision of trunk3.26e-09113
lung5.16e-0922
respiratory tube5.16e-0922
respiration organ5.16e-0922
pair of lungs5.16e-0922
lung primordium5.16e-0922
lung bud5.16e-0922
organ segment6.93e-0997
anatomical system7.81e-09625
anatomical group1.00e-08626
orifice1.46e-0835
epithelial bud2.68e-0837
gastrointestinal system4.47e-0835
organ part5.59e-08219
gut epithelium7.56e-0854
organism subdivision7.56e-08365
anatomical conduit1.27e-07241
gland1.34e-0759
thoracic segment of trunk2.33e-0752
anatomical cluster5.62e-07286
respiratory system epithelium7.23e-0728
respiratory tract epithelium8.03e-0719
lung epithelium8.03e-0719
oral opening8.11e-0721
Disease
Ontology termp-valuen
carcinoma1.80e-26106
cell type cancer1.55e-16143
adenocarcinoma3.47e-0725


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.