Personal tools

Coexpression cluster:C3089

From FANTOM5_SSTAR

Revision as of 18:53, 8 August 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Full id: C3089_caudate_pons_diencephalon_locus_parietal_globus_paracentral



Phase1 CAGE Peaks

Hg19::chr11:118023585..118023592,-p7@SCN4B
Hg19::chr11:118023594..118023635,-p2@SCN4B
Hg19::chr11:118023653..118023665,-p5@SCN4B


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.27e-52115
neural tube1.47e-4257
neural rod1.47e-4257
future spinal cord1.47e-4257
neural keel1.47e-4257
central nervous system1.36e-3582
neural plate1.38e-3586
presumptive neural plate1.38e-3586
regional part of brain1.86e-3459
neurectoderm3.26e-3490
brain1.05e-3169
future brain1.05e-3169
regional part of nervous system6.45e-3194
nervous system6.45e-3194
ectoderm-derived structure2.44e-30169
ectoderm8.27e-30173
presumptive ectoderm8.27e-30173
regional part of forebrain2.15e-2941
forebrain2.15e-2941
future forebrain2.15e-2941
anterior region of body5.11e-29129
craniocervical region5.11e-29129
anterior neural tube2.45e-2842
gray matter2.76e-2834
brain grey matter2.76e-2834
telencephalon4.84e-2834
head3.37e-27123
cerebral hemisphere3.57e-2732
regional part of telencephalon5.74e-2733
pre-chordal neural plate1.46e-2161
cerebral cortex5.57e-2025
pallium5.57e-2025
regional part of cerebral cortex1.13e-1722
neocortex1.93e-1620
posterior neural tube2.37e-1515
chordal neural plate2.37e-1515
organ part1.34e-13219
segmental subdivision of hindbrain1.82e-1212
hindbrain1.82e-1212
presumptive hindbrain1.82e-1212
multi-tissue structure1.74e-11347
cell layer2.75e-11312
epithelium3.39e-11309
segmental subdivision of nervous system3.65e-1113
anatomical conduit6.41e-11241
organism subdivision7.41e-11365
anatomical cluster5.76e-10286
nucleus of brain8.44e-109
neural nucleus8.44e-109
regional part of metencephalon1.39e-099
metencephalon1.39e-099
future metencephalon1.39e-099
basal ganglion2.29e-099
nuclear complex of neuraxis2.29e-099
aggregate regional part of brain2.29e-099
collection of basal ganglia2.29e-099
cerebral subcortex2.29e-099
tube4.39e-09194
organ1.01e-08511
embryo2.26e-08612
telencephalic nucleus7.55e-087
gyrus9.78e-086
multi-cellular organism9.36e-07659


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.