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Coexpression cluster:C4178

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Full id: C4178_temporal_parietal_duodenum_occipital_adrenal_seminal_rhabdomyosarcoma



Phase1 CAGE Peaks

Hg19::chr2:212842252..212842257,-p@chr2:212842252..212842257
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Hg19::chr2:213296026..213296031,-p@chr2:213296026..213296031
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Hg19::chr2:213315541..213315545,-p@chr2:213315541..213315545
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.56e-44115
neural tube2.04e-4457
neural rod2.04e-4457
future spinal cord2.04e-4457
neural keel2.04e-4457
neural plate1.52e-3986
presumptive neural plate1.52e-3986
neurectoderm1.93e-3990
anterior neural tube4.29e-3842
regional part of forebrain2.37e-3741
forebrain2.37e-3741
future forebrain2.37e-3741
central nervous system2.08e-3682
regional part of brain2.10e-3659
regional part of nervous system1.87e-3494
nervous system1.87e-3494
brain1.71e-3169
future brain1.71e-3169
gray matter6.99e-3134
brain grey matter6.99e-3134
telencephalon1.78e-3034
regional part of telencephalon1.39e-2933
pre-chordal neural plate9.16e-2961
cerebral hemisphere1.49e-2832
ectoderm9.28e-25173
presumptive ectoderm9.28e-25173
ectoderm-derived structure2.48e-24169
head3.30e-22123
anterior region of body4.40e-22129
craniocervical region4.40e-22129
regional part of cerebral cortex6.23e-2222
cerebral cortex9.50e-2225
pallium9.50e-2225
neocortex1.11e-1920
tube2.29e-12194
nucleus of brain1.29e-109
neural nucleus1.29e-109
anatomical conduit1.41e-10241
basal ganglion1.51e-109
nuclear complex of neuraxis1.51e-109
aggregate regional part of brain1.51e-109
collection of basal ganglia1.51e-109
cerebral subcortex1.51e-109
temporal lobe1.75e-097
brainstem3.64e-098
anatomical cluster4.78e-09286
telencephalic nucleus1.56e-087
organ2.22e-08511
diencephalon3.13e-087
future diencephalon3.13e-087
posterior neural tube5.61e-0815
chordal neural plate5.61e-0815
epithelium1.12e-07309
cell layer2.20e-07312
organism subdivision2.85e-07365
gyrus2.98e-076
organ part5.26e-07219
limbic system8.97e-075


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.