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{{Coexpression_clusters
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|id=C2226
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0001017!4.91e-60!82;UBERON:0005743!9.14e-59!86;UBERON:0001049!4.85e-57!57;UBERON:0005068!4.85e-57!57;UBERON:0006241!4.85e-57!57;UBERON:0007135!4.85e-57!57;UBERON:0000955!4.21e-56!69;UBERON:0006238!4.21e-56!69;UBERON:0000073!8.10e-54!94;UBERON:0001016!8.10e-54!94;UBERON:0002616!1.18e-49!59;UBERON:0001893!3.55e-49!34;UBERON:0002020!3.75e-48!34;UBERON:0003528!3.75e-48!34;UBERON:0002780!3.91e-48!41;UBERON:0001890!3.91e-48!41;UBERON:0006240!3.91e-48!41;UBERON:0002791!2.65e-47!33;UBERON:0003080!9.88e-47!42;UBERON:0001869!3.27e-46!32;UBERON:0003075!4.98e-46!86;UBERON:0007284!4.98e-46!86;UBERON:0002346!3.18e-45!90;UBERON:0003056!8.27e-35!61;UBERON:0000956!9.53e-34!25;UBERON:0000203!9.53e-34!25;UBERON:0002619!9.53e-33!22;UBERON:0001950!2.24e-29!20;UBERON:0000924!4.65e-29!173;UBERON:0006601!4.65e-29!173;UBERON:0004121!5.70e-29!169;UBERON:0000033!6.68e-29!123;UBERON:0000153!8.10e-27!129;UBERON:0007811!8.10e-27!129;UBERON:0007023!4.35e-24!115;UBERON:0002420!7.76e-17!9;UBERON:0007245!7.76e-17!9;UBERON:0010009!7.76e-17!9;UBERON:0010011!7.76e-17!9;UBERON:0000454!7.76e-17!9;UBERON:0002308!9.55e-16!9;UBERON:0000125!9.55e-16!9;UBERON:0009663!1.65e-13!7;UBERON:0000025!2.58e-12!194;UBERON:0000200!3.35e-12!6;UBERON:0001871!1.31e-11!7;UBERON:0003076!2.03e-11!15;UBERON:0003057!2.03e-11!15;UBERON:0000064!6.89e-11!219;UBERON:0000349!3.03e-10!5;UBERON:0000483!3.39e-10!309;UBERON:0001872!6.12e-10!5;UBERON:0004733!6.14e-10!12;UBERON:0002028!6.14e-10!12;UBERON:0007277!6.14e-10!12;UBERON:0000119!6.22e-10!312;UBERON:0004732!4.97e-09!13;UBERON:0000369!5.15e-09!4;UBERON:0002435!5.15e-09!4;UBERON:0000204!5.15e-09!4;UBERON:0010082!5.15e-09!4;UBERON:0000475!5.86e-09!365;UBERON:0002680!1.64e-08!9;UBERON:0001895!1.64e-08!9;UBERON:0010092!1.64e-08!9;UBERON:0004111!2.94e-08!241;UBERON:0005383!4.08e-07!3;UBERON:0005382!4.08e-07!3;UBERON:0002298!8.18e-07!8
}}

Latest revision as of 12:01, 17 September 2013


Full id: C2226_putamen_diencephalon_nucleus_brain_temporal_insula_caudate



Phase1 CAGE Peaks

Hg19::chr12:58027138..58027159,-p8@B4GALNT1
Hg19::chr1:33359673..33359704,-p@chr1:33359673..33359704
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Hg19::chr1:33359734..33359745,-p@chr1:33359734..33359745
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Hg19::chr1:33360078..33360094,-p@chr1:33360078..33360094
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
brain7.39e-5768
future brain7.39e-5768
regional part of nervous system6.11e-5453
regional part of brain6.11e-5453
central nervous system1.35e-5281
neural tube1.03e-5056
neural rod1.03e-5056
future spinal cord1.03e-5056
neural keel1.03e-5056
telencephalon1.18e-4934
nervous system1.37e-4989
regional part of forebrain8.72e-4941
forebrain8.72e-4941
anterior neural tube8.72e-4941
future forebrain8.72e-4941
cerebral hemisphere2.77e-4832
regional part of telencephalon1.89e-4332
neurectoderm9.65e-4186
brain grey matter1.14e-4034
gray matter1.14e-4034
regional part of cerebral cortex1.71e-4022
neural plate2.41e-4082
presumptive neural plate2.41e-4082
pre-chordal neural plate7.87e-4061
cerebral cortex2.34e-3525
pallium2.34e-3525
neocortex4.13e-3420
ecto-epithelium1.81e-32104
ectoderm-derived structure2.47e-28171
ectoderm2.47e-28171
presumptive ectoderm2.47e-28171
adult organism2.62e-27114
structure with developmental contribution from neural crest1.22e-25132
gyrus9.59e-246
organ system subdivision2.42e-18223
temporal lobe5.69e-146
limbic system5.72e-135
frontal cortex1.09e-123
basal ganglion5.15e-119
nuclear complex of neuraxis5.15e-119
aggregate regional part of brain5.15e-119
collection of basal ganglia5.15e-119
cerebral subcortex5.15e-119
tube6.50e-11192
corpus striatum4.39e-104
striatum4.39e-104
ventral part of telencephalon4.39e-104
future corpus striatum4.39e-104
telencephalic nucleus1.75e-097
middle temporal gyrus6.47e-092
middle frontal gyrus7.00e-092
anatomical cluster8.96e-09373
Ammon's horn9.94e-092
lobe parts of cerebral cortex9.94e-092
hippocampal formation9.94e-092
limbic lobe9.94e-092
organ part1.02e-08218
anatomical conduit4.33e-08240
parietal lobe7.97e-085
neural nucleus2.26e-079
nucleus of brain2.26e-079
segmental subdivision of hindbrain2.70e-0712
hindbrain2.70e-0712
presumptive hindbrain2.70e-0712
epithelium2.78e-07306
cell layer3.87e-07309


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.443649
MA0004.10.71247
MA0006.10.532262
MA0007.10.6918
MA0009.11.20602
MA0014.10.0695829
MA0017.10.577281
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.11.66718
MA0051.10.820063
MA0052.11.12718
MA0055.10.125954
MA0056.10
MA0057.10.69331
MA0058.10.605914
MA0059.10.604454
MA0060.10.393285
MA0061.11.68681
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.11.52107
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.16.9203
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.10.182167
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.11.9583
MA0101.10.539569
MA0103.10.521546
MA0105.11.90157
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.10.447443
MA0115.11.45393
MA0116.12.01976
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.11.08195
MA0146.10.221129
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.21.13403
MA0138.20.928035
MA0002.20.379056
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.21.05083
MA0065.22.43626
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.11.21162
MA0155.11.02191
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.10.309472
MA0163.13.14178
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.22.72671
MA0102.21.75932
MA0258.10.418966
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.