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{{Coexpression_clusters
{
|full_id=C2217_mature_skeletal_neuroepithelioma_neuroectodermal_argyrophil_breast_left

Latest revision as of 12:01, 17 September 2013


Full id: C2217_mature_skeletal_neuroepithelioma_neuroectodermal_argyrophil_breast_left



Phase1 CAGE Peaks

Hg19::chr12:54982378..54982417,-p2@PPP1R1A
Hg19::chr12:54982420..54982461,-p1@PPP1R1A
Hg19::chr12:54982586..54982628,-p3@PPP1R1A
Hg19::chr12:54983026..54983043,-p@chr12:54983026..54983043
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
fat cell6.89e-0915
Uber Anatomy
Ontology termp-valuen
adult organism1.22e-57114
neural tube6.71e-3356
neural rod6.71e-3356
future spinal cord6.71e-3356
neural keel6.71e-3356
central nervous system4.88e-3181
regional part of nervous system1.13e-3053
regional part of brain1.13e-3053
nervous system1.25e-2989
telencephalon5.33e-2834
brain grey matter7.52e-2834
gray matter7.52e-2834
cerebral hemisphere1.32e-2632
regional part of telencephalon1.77e-2632
neurectoderm4.22e-2686
regional part of forebrain4.66e-2641
forebrain4.66e-2641
anterior neural tube4.66e-2641
future forebrain4.66e-2641
brain1.56e-2368
future brain1.56e-2368
neural plate3.22e-2382
presumptive neural plate3.22e-2382
cerebral cortex2.50e-2025
pallium2.50e-2025
regional part of cerebral cortex1.32e-1922
organ system subdivision1.19e-18223
neocortex3.96e-1820
ecto-epithelium1.81e-17104
ectoderm-derived structure4.41e-17171
ectoderm4.41e-17171
presumptive ectoderm4.41e-17171
pre-chordal neural plate7.92e-1661
structure with developmental contribution from neural crest1.95e-14132
anatomical cluster1.58e-13373
tube3.76e-12192
anatomical conduit7.04e-11240
multi-tissue structure1.76e-10342
embryo1.81e-09592
basal ganglion2.30e-099
nuclear complex of neuraxis2.30e-099
aggregate regional part of brain2.30e-099
collection of basal ganglia2.30e-099
cerebral subcortex2.30e-099
neural nucleus5.90e-099
nucleus of brain5.90e-099
multi-cellular organism7.73e-09656
organ part4.91e-08218
posterior neural tube4.97e-0815
chordal neural plate4.97e-0815
cavitated compound organ6.86e-0831
compound organ8.90e-0868
developing anatomical structure1.03e-07581
telencephalic nucleus1.19e-077
organ5.12e-07503
temporal lobe5.65e-076


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.12.39007
MA0004.10.71247
MA0006.10.532262
MA0007.10.6918
MA0009.11.20602
MA0014.12.45009
MA0017.11.41335
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.10.69864
MA0051.10.820063
MA0052.11.12718
MA0055.10.396851
MA0056.10
MA0057.11.98521
MA0058.10.605914
MA0059.10.604454
MA0060.11.01899
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.841508
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.17.60032
MA0074.11.91637
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.10.182167
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.10.521546
MA0105.10.232357
MA0106.13.33935
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.10.447443
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.11.08195
MA0146.10.221129
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.23.07509
MA0138.20.928035
MA0002.20.379056
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.20.187982
MA0065.21.09513
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.10.229241
MA0155.11.61785
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.10.0928415
MA0163.11.90765
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.24.43857
MA0102.21.75932
MA0258.10.418966
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.