MCL coexpression mm9:1723
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr18:82754158..82754162,+ | p@chr18:82754158..82754162 + |
| Mm9::chr1:187242150..187242173,+ | p@chr1:187242150..187242173 + |
| Mm9::chr2:102627166..102627177,+ | p@chr2:102627166..102627177 + |
| Mm9::chr7:116902855..116902862,- | p@chr7:116902855..116902862 - |
| Mm9::chr7:116903722..116903727,- | p@chr7:116903722..116903727 - |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0019911 | structural constituent of myelin sheath | 0.00591602515206222 |
| GO:0015501 | glutamate:sodium symporter activity | 0.00591602515206222 |
| GO:0015813 | L-glutamate transport | 0.00591602515206222 |
| GO:0015800 | acidic amino acid transport | 0.00591602515206222 |
| GO:0043209 | myelin sheath | 0.00591602515206222 |
| GO:0005313 | L-glutamate transmembrane transporter activity | 0.00591602515206222 |
| GO:0005283 | sodium:amino acid symporter activity | 0.00591602515206222 |
| GO:0015172 | acidic amino acid transmembrane transporter activity | 0.00591602515206222 |
| GO:0017153 | sodium:dicarboxylate symporter activity | 0.006572640891973 |
| GO:0005416 | cation:amino acid symporter activity | 0.006572640891973 |
| GO:0005310 | dicarboxylic acid transmembrane transporter activity | 0.006572640891973 |
| GO:0006835 | dicarboxylic acid transport | 0.006572640891973 |
| GO:0015296 | anion:cation symporter activity | 0.0107013754591181 |
| GO:0005343 | organic acid:sodium symporter activity | 0.0107013754591181 |
| GO:0015179 | L-amino acid transmembrane transporter activity | 0.0120893513204155 |
| GO:0042552 | myelination | 0.0127004901604651 |
| GO:0007272 | ensheathment of neurons | 0.0127004901604651 |
| GO:0008366 | axon ensheathment | 0.0127004901604651 |
| GO:0005275 | amine transmembrane transporter activity | 0.0138861597757711 |
| GO:0015171 | amino acid transmembrane transporter activity | 0.0138861597757711 |
| GO:0001508 | regulation of action potential | 0.0138861597757711 |
| GO:0015370 | solute:sodium symporter activity | 0.0143285192318228 |
| GO:0006865 | amino acid transport | 0.0154166184691794 |
| GO:0015294 | solute:cation symporter activity | 0.0157527264978516 |
| GO:0015837 | amine transport | 0.0157527264978516 |
| GO:0046943 | carboxylic acid transmembrane transporter activity | 0.0157527264978516 |
| GO:0005342 | organic acid transmembrane transporter activity | 0.0157527264978516 |
| GO:0044459 | plasma membrane part | 0.0157527264978516 |
| GO:0046942 | carboxylic acid transport | 0.0157527264978516 |
| GO:0015849 | organic acid transport | 0.0157527264978516 |
| GO:0005886 | plasma membrane | 0.0249424292848134 |
| GO:0008509 | anion transmembrane transporter activity | 0.0275279381811922 |
| GO:0015293 | symporter activity | 0.0316805465969565 |
| GO:0015291 | secondary active transmembrane transporter activity | 0.0406419911411715 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| CNS neuron (sensu Vertebrata) | 3.36e-21 | 23 |
| neuroblast (sensu Vertebrata) | 3.36e-21 | 23 |
| neuron | 4.25e-14 | 33 |
| neuronal stem cell | 4.25e-14 | 33 |
| neuroblast | 4.25e-14 | 33 |
| electrically signaling cell | 4.25e-14 | 33 |
| raphe nuclei neuron | 1.92e-12 | 3 |
| neuron of the substantia nigra | 2.95e-12 | 3 |
| electrically responsive cell | 1.39e-11 | 39 |
| electrically active cell | 1.39e-11 | 39 |
| neuron of the ventral spinal cord | 1.57e-11 | 3 |
| neural cell | 2.68e-10 | 43 |
| ectodermal cell | 5.16e-10 | 44 |
| neurectodermal cell | 5.16e-10 | 44 |
| non-terminally differentiated cell | 9.17e-09 | 49 |
| neuron of the dorsal spinal cord | 3.49e-08 | 2 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0185483 |
| MA0004.1 | 0.603793 |
| MA0006.1 | 0.419915 |
| MA0007.1 | 0.587678 |
| MA0009.1 | 1.06266 |
| MA0014.1 | 0.0502051 |
| MA0017.1 | 0.449113 |
| MA0019.1 | 0.874061 |
| MA0024.1 | 1.01759 |
| MA0025.1 | 1.30092 |
| MA0027.1 | 2.72141 |
| MA0028.1 | 0.43138 |
| MA0029.1 | 0.995171 |
| MA0030.1 | 1.00195 |
| MA0031.1 | 0.965177 |
| MA0038.1 | 0.757669 |
| MA0040.1 | 1.07552 |
| MA0041.1 | 1.29634 |
| MA0042.1 | 0.507715 |
| MA0043.1 | 1.1618 |
| MA0046.1 | 1.09955 |
| MA0048.1 | 0.205696 |
| MA0050.1 | 0.645342 |
| MA0051.1 | 0.767098 |
| MA0052.1 | 1.08379 |
| MA0055.1 | 0.0851423 |
| MA0056.1 | 0 |
| MA0057.1 | 1.06992 |
| MA0058.1 | 0.50032 |
| MA0059.1 | 0.513699 |
| MA0060.1 | 0.330907 |
| MA0061.1 | 0.364227 |
| MA0063.1 | 0 |
| MA0066.1 | 0.746072 |
| MA0067.1 | 1.41352 |
| MA0068.1 | 0.197245 |
| MA0069.1 | 1.08414 |
| MA0070.1 | 1.07418 |
| MA0071.1 | 0.644448 |
| MA0072.1 | 2.41915 |
| MA0073.1 | 0.00450236 |
| MA0074.1 | 0.708108 |
| MA0076.1 | 0.470037 |
| MA0077.1 | 1.04318 |
| MA0078.1 | 0.801834 |
| MA0081.1 | 1.33193 |
| MA0083.1 | 1.16099 |
| MA0084.1 | 1.74401 |
| MA0087.1 | 1.11687 |
| MA0088.1 | 0.453686 |
| MA0089.1 | 0 |
| MA0090.1 | 0.566938 |
| MA0091.1 | 0.617887 |
| MA0092.1 | 0.567278 |
| MA0093.1 | 0.440484 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.695835 |
| MA0101.1 | 0.523409 |
| MA0103.1 | 0.460936 |
| MA0105.1 | 0.248108 |
| MA0106.1 | 0.809991 |
| MA0107.1 | 0.454197 |
| MA0108.2 | 0.897859 |
| MA0109.1 | 0 |
| MA0111.1 | 0.582193 |
| MA0113.1 | 0.780358 |
| MA0114.1 | 0.361633 |
| MA0115.1 | 1.16466 |
| MA0116.1 | 0.419688 |
| MA0117.1 | 1.13165 |
| MA0119.1 | 0.524046 |
| MA0122.1 | 1.15196 |
| MA0124.1 | 1.35963 |
| MA0125.1 | 1.28445 |
| MA0130.1 | 0 |
| MA0131.1 | 0.869325 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.19898 |
| MA0136.1 | 0.729175 |
| MA0139.1 | 0.8026 |
| MA0140.1 | 0.695713 |
| MA0141.1 | 0.482463 |
| MA0142.1 | 0.950155 |
| MA0143.1 | 0.797553 |
| MA0144.1 | 0.365053 |
| MA0145.1 | 0.157686 |
| MA0146.1 | 0.0604336 |
| MA0147.1 | 0.378658 |
| MA0148.1 | 0.621195 |
| MA0149.1 | 0.529387 |
| MA0062.2 | 0.254018 |
| MA0035.2 | 0.700704 |
| MA0039.2 | 0.0102623 |
| MA0138.2 | 0.861035 |
| MA0002.2 | 0.299191 |
| MA0137.2 | 0.479301 |
| MA0104.2 | 0.315156 |
| MA0047.2 | 0.75686 |
| MA0112.2 | 0.157681 |
| MA0065.2 | 0.477991 |
| MA0150.1 | 0.587557 |
| MA0151.1 | 0 |
| MA0152.1 | 0.756973 |
| MA0153.1 | 1.21594 |
| MA0154.1 | 0.203217 |
| MA0155.1 | 0.173445 |
| MA0156.1 | 0.469089 |
| MA0157.1 | 0.91689 |
| MA0158.1 | 0 |
| MA0159.1 | 0.389847 |
| MA0160.1 | 0.624415 |
| MA0161.1 | 0 |
| MA0162.1 | 0.0699535 |
| MA0163.1 | 0.0644585 |
| MA0164.1 | 0.729558 |
| MA0080.2 | 0.455167 |
| MA0018.2 | 0.739807 |
| MA0099.2 | 0.854449 |
| MA0079.2 | 0.00167664 |
| MA0102.2 | 1.79669 |
| MA0258.1 | 0.346619 |
| MA0259.1 | 0.366802 |
| MA0442.1 | 0 |
