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Coexpression cluster:C946

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Full id: C946_medial_smallcell_hippocampus_occipital_amygdala_cerebellum_caudate



Phase1 CAGE Peaks

Hg19::chr4:166385564..166385605,+p@chr4:166385564..166385605
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Hg19::chr4:166388856..166388876,+p@chr4:166388856..166388876
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Hg19::chr4:166388881..166388892,+p@chr4:166388881..166388892
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Hg19::chr4:166405567..166405604,+p@chr4:166405567..166405604
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Hg19::chr4:166405628..166405640,+p@chr4:166405628..166405640
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Hg19::chr4:166405645..166405677,+p@chr4:166405645..166405677
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Hg19::chr4:166408624..166408674,+p@chr4:166408624..166408674
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Hg19::chr4:166408687..166408701,+p@chr4:166408687..166408701
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Hg19::chr4:166414322..166414353,+p@chr4:166414322..166414353
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.82e-5056
neural rod1.82e-5056
future spinal cord1.82e-5056
neural keel1.82e-5056
regional part of nervous system1.10e-4653
regional part of brain1.10e-4653
adult organism7.66e-45114
central nervous system3.47e-4481
nervous system3.19e-4089
brain4.07e-4068
future brain4.07e-4068
neurectoderm7.24e-4086
regional part of forebrain2.17e-3841
forebrain2.17e-3841
anterior neural tube2.17e-3841
future forebrain2.17e-3841
neural plate4.32e-3882
presumptive neural plate4.32e-3882
brain grey matter2.96e-3134
gray matter2.96e-3134
telencephalon1.09e-3034
ecto-epithelium2.42e-29104
regional part of telencephalon5.20e-2932
cerebral hemisphere6.99e-2932
organ system subdivision3.78e-27223
pre-chordal neural plate3.32e-2661
regional part of cerebral cortex5.77e-2522
structure with developmental contribution from neural crest1.53e-24132
ectoderm-derived structure1.68e-24171
ectoderm1.68e-24171
presumptive ectoderm1.68e-24171
neocortex2.55e-2220
cerebral cortex3.97e-2125
pallium3.97e-2125
tube7.72e-16192
anatomical cluster5.61e-15373
anatomical conduit3.43e-14240
posterior neural tube7.65e-1315
chordal neural plate7.65e-1315
basal ganglion3.15e-129
nuclear complex of neuraxis3.15e-129
aggregate regional part of brain3.15e-129
collection of basal ganglia3.15e-129
cerebral subcortex3.15e-129
neural nucleus9.16e-129
nucleus of brain9.16e-129
organ part4.59e-11218
multi-tissue structure7.27e-10342
telencephalic nucleus1.48e-097
segmental subdivision of hindbrain2.11e-0912
hindbrain2.11e-0912
presumptive hindbrain2.11e-0912
cell layer3.00e-09309
organ3.32e-09503
epithelium3.37e-09306
diencephalon4.13e-097
future diencephalon4.13e-097
segmental subdivision of nervous system1.81e-0813
gyrus1.85e-086
limbic system1.02e-075
brainstem1.33e-076
temporal lobe1.37e-076
occipital lobe3.72e-075


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.