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Coexpression cluster:C4737

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Full id: C4737_heart_small_parotid_liver_skeletal_salivary_Hepatocyte



Phase1 CAGE Peaks

Hg19::chr8:145726481..145726526,+p@chr8:145726481..145726526
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Hg19::chr8:145726529..145726554,+p@chr8:145726529..145726554
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Hg19::chr8:145726555..145726570,+p@chr8:145726555..145726570
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.12e-31115
embryo6.03e-20612
multi-cellular organism2.54e-19659
embryonic structure1.61e-17605
developing anatomical structure1.61e-17605
germ layer4.03e-17604
embryonic tissue4.03e-17604
presumptive structure4.03e-17604
epiblast (generic)4.03e-17604
multi-tissue structure9.33e-17347
anatomical conduit1.12e-15241
neural plate6.10e-1586
presumptive neural plate6.10e-1586
anatomical system1.02e-14625
anatomical group1.90e-14626
neural tube2.65e-1457
neural rod2.65e-1457
future spinal cord2.65e-1457
neural keel2.65e-1457
neurectoderm4.38e-1490
epithelium1.74e-13309
tube2.94e-13194
pre-chordal neural plate3.25e-1361
anatomical cluster3.70e-13286
regional part of brain7.56e-1359
anterior neural tube7.69e-1342
cell layer1.25e-12312
regional part of forebrain2.36e-1241
forebrain2.36e-1241
future forebrain2.36e-1241
organ3.44e-12511
central nervous system9.92e-1282
telencephalon4.69e-1134
gray matter6.38e-1134
brain grey matter6.38e-1134
regional part of telencephalon1.03e-1033
cerebral hemisphere1.29e-1032
regional part of nervous system2.20e-1094
nervous system2.20e-1094
head2.53e-10123
anterior region of body4.38e-10129
craniocervical region4.38e-10129
organ part7.08e-10219
brain8.44e-1069
future brain8.44e-1069
ectoderm-derived structure2.50e-09169
organism subdivision3.09e-09365
ectoderm5.39e-09173
presumptive ectoderm5.39e-09173
cerebral cortex2.22e-0825
pallium2.22e-0825
tissue7.30e-08787
compound organ8.98e-0869
regional part of cerebral cortex1.05e-0722
immaterial anatomical entity1.06e-07126
trunk region element1.75e-07107
exocrine gland1.89e-0731
exocrine system1.89e-0731
neocortex4.66e-0720
abdomen element8.05e-0755
abdominal segment element8.05e-0755


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.