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MCL coexpression mm9:1723

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Phase1 CAGE Peaks

 Short description
Mm9::chr18:82754158..82754162,+p@chr18:82754158..82754162
+
Mm9::chr1:187242150..187242173,+p@chr1:187242150..187242173
+
Mm9::chr2:102627166..102627177,+p@chr2:102627166..102627177
+
Mm9::chr7:116902855..116902862,-p@chr7:116902855..116902862
-
Mm9::chr7:116903722..116903727,-p@chr7:116903722..116903727
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0019911structural constituent of myelin sheath0.00591602515206222
GO:0015501glutamate:sodium symporter activity0.00591602515206222
GO:0015813L-glutamate transport0.00591602515206222
GO:0015800acidic amino acid transport0.00591602515206222
GO:0043209myelin sheath0.00591602515206222
GO:0005313L-glutamate transmembrane transporter activity0.00591602515206222
GO:0005283sodium:amino acid symporter activity0.00591602515206222
GO:0015172acidic amino acid transmembrane transporter activity0.00591602515206222
GO:0017153sodium:dicarboxylate symporter activity0.006572640891973
GO:0005416cation:amino acid symporter activity0.006572640891973
GO:0005310dicarboxylic acid transmembrane transporter activity0.006572640891973
GO:0006835dicarboxylic acid transport0.006572640891973
GO:0015296anion:cation symporter activity0.0107013754591181
GO:0005343organic acid:sodium symporter activity0.0107013754591181
GO:0015179L-amino acid transmembrane transporter activity0.0120893513204155
GO:0042552myelination0.0127004901604651
GO:0007272ensheathment of neurons0.0127004901604651
GO:0008366axon ensheathment0.0127004901604651
GO:0005275amine transmembrane transporter activity0.0138861597757711
GO:0015171amino acid transmembrane transporter activity0.0138861597757711
GO:0001508regulation of action potential0.0138861597757711
GO:0015370solute:sodium symporter activity0.0143285192318228
GO:0006865amino acid transport0.0154166184691794
GO:0015294solute:cation symporter activity0.0157527264978516
GO:0015837amine transport0.0157527264978516
GO:0046943carboxylic acid transmembrane transporter activity0.0157527264978516
GO:0005342organic acid transmembrane transporter activity0.0157527264978516
GO:0044459plasma membrane part0.0157527264978516
GO:0046942carboxylic acid transport0.0157527264978516
GO:0015849organic acid transport0.0157527264978516
GO:0005886plasma membrane0.0249424292848134
GO:0008509anion transmembrane transporter activity0.0275279381811922
GO:0015293symporter activity0.0316805465969565
GO:0015291secondary active transmembrane transporter activity0.0406419911411715



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of nervous system6.44e-3254
neural tube8.82e-2752
neural rod8.82e-2752
future spinal cord8.82e-2752
neural keel8.82e-2752
central nervous system7.50e-2573
gray matter3.52e-2434
nervous system4.38e-2475
spinal cord3.92e-216
dorsal region element3.92e-216
dorsum3.92e-216
neurectoderm4.58e-2164
neural plate4.58e-2164
presumptive neural plate4.58e-2164
ectoderm-derived structure3.49e-1895
ectoderm3.49e-1895
presumptive ectoderm3.49e-1895
regional part of spinal cord4.56e-185
gray matter of spinal cord4.56e-185
ecto-epithelium5.25e-1873
regional part of midbrain2.90e-154
midbrain2.90e-154
presumptive midbrain2.90e-154
midbrain neural tube2.90e-154
anterior neural tube6.82e-1540
regional part of brain1.02e-1446
brain2.41e-1447
future brain2.41e-1447
posterior neural tube5.43e-1412
chordal neural plate5.43e-1412
structure with developmental contribution from neural crest1.67e-1392
regional part of forebrain3.79e-1339
forebrain3.79e-1339
future forebrain3.79e-1339
brain grey matter4.31e-1329
regional part of telencephalon4.31e-1329
telencephalon4.31e-1329
raphe nuclei1.92e-123
reticular formation1.92e-123
occipital lobe2.58e-1210
visual cortex2.58e-1210
neocortex2.58e-1210
substantia nigra2.95e-123
telencephalic nucleus2.95e-123
midbrain nucleus2.95e-123
neural nucleus2.95e-123
nucleus of brain2.95e-123
pre-chordal neural plate1.13e-1149
ventral horn of spinal cord1.57e-113
tube3.74e-10114
regional part of cerebral cortex2.09e-0917
anatomical conduit3.12e-09122
dorsal horn of spinal cord3.49e-082
basal ganglion1.38e-078
nuclear complex of neuraxis1.38e-078
aggregate regional part of brain1.38e-078
collection of basal ganglia1.38e-078
cerebral subcortex1.38e-078
cerebral cortex1.87e-0721
cerebral hemisphere1.87e-0721
pallium1.87e-0721
organ system subdivision8.89e-07194


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0185483
MA0004.10.603793
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.10.0502051
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.10.43138
MA0029.10.995171
MA0030.11.00195
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.11.29634
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.10.205696
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.0851423
MA0056.10
MA0057.11.06992
MA0058.10.50032
MA0059.10.513699
MA0060.10.330907
MA0061.10.364227
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.10.197245
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.12.41915
MA0073.10.00450236
MA0074.10.708108
MA0076.10.470037
MA0077.11.04318
MA0078.10.801834
MA0081.11.33193
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.10.453686
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.10.440484
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.10.460936
MA0105.10.248108
MA0106.10.809991
MA0107.10.454197
MA0108.20.897859
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.361633
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.10.869325
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.8026
MA0140.10.695713
MA0141.10.482463
MA0142.10.950155
MA0143.10.797553
MA0144.10.365053
MA0145.10.157686
MA0146.10.0604336
MA0147.10.378658
MA0148.10.621195
MA0149.10.529387
MA0062.20.254018
MA0035.20.700704
MA0039.20.0102623
MA0138.20.861035
MA0002.20.299191
MA0137.20.479301
MA0104.20.315156
MA0047.20.75686
MA0112.20.157681
MA0065.20.477991
MA0150.10.587557
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.203217
MA0155.10.173445
MA0156.10.469089
MA0157.10.91689
MA0158.10
MA0159.10.389847
MA0160.10.624415
MA0161.10
MA0162.10.0699535
MA0163.10.0644585
MA0164.10.729558
MA0080.20.455167
MA0018.20.739807
MA0099.20.854449
MA0079.20.00167664
MA0102.21.79669
MA0258.10.346619
MA0259.10.366802
MA0442.10