Personal tools

Coexpression cluster:C4637

From FANTOM5_SSTAR

Jump to: navigation, search


Full id: C4637_Smooth_leiomyoma_mesenchymal_Iris_glioblastoma_Lens_Ciliary



Phase1 CAGE Peaks

Hg19::chr7:102553382..102553397,+p3@LRRC17
Hg19::chr7:102553430..102553456,+p1@LRRC17
Hg19::chr7:102553470..102553487,+p2@LRRC17


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
skeletal muscle tissue1.82e-3162
striated muscle tissue1.82e-3162
myotome1.82e-3162
muscle tissue2.05e-3164
musculature2.05e-3164
musculature of body2.05e-3164
dense mesenchyme tissue3.14e-3073
somite6.15e-3071
presomitic mesoderm6.15e-3071
presumptive segmental plate6.15e-3071
dermomyotome6.15e-3071
trunk paraxial mesoderm6.15e-3071
paraxial mesoderm9.94e-3072
presumptive paraxial mesoderm9.94e-3072
epithelial vesicle4.47e-2878
splanchnic layer of lateral plate mesoderm1.40e-2483
multilaminar epithelium3.09e-2383
vasculature4.81e-2178
vascular system4.81e-2178
trunk mesenchyme5.77e-20122
cardiovascular system1.68e-19109
mesenchyme5.32e-19160
entire embryonic mesenchyme5.32e-19160
circulatory system5.75e-19112
artery8.98e-1942
arterial blood vessel8.98e-1942
arterial system8.98e-1942
unilaminar epithelium9.68e-19148
epithelial tube3.56e-17117
epithelial tube open at both ends4.49e-1759
blood vessel4.49e-1759
blood vasculature4.49e-1759
vascular cord4.49e-1759
systemic artery4.77e-1733
systemic arterial system4.77e-1733
vessel4.05e-1568
mesoderm1.17e-14315
mesoderm-derived structure1.17e-14315
presumptive mesoderm1.17e-14315
cell layer4.79e-14309
anatomical cluster2.09e-13373
multi-tissue structure3.60e-13342
epithelium4.99e-13306
organism subdivision5.59e-13264
multi-cellular organism7.76e-12656
heart4.54e-1124
primitive heart tube4.54e-1124
primary heart field4.54e-1124
anterior lateral plate mesoderm4.54e-1124
heart tube4.54e-1124
heart primordium4.54e-1124
cardiac mesoderm4.54e-1124
cardiogenic plate4.54e-1124
heart rudiment4.54e-1124
embryonic structure1.55e-10564
tissue1.65e-10773
trunk1.83e-10199
germ layer3.06e-10560
germ layer / neural crest3.06e-10560
embryonic tissue3.06e-10560
presumptive structure3.06e-10560
germ layer / neural crest derived structure3.06e-10560
epiblast (generic)3.06e-10560
anatomical system3.08e-10624
developing anatomical structure3.66e-10581
anatomical group4.42e-10625
primary circulatory organ6.92e-1027
smooth muscle tissue8.49e-1015
embryo9.72e-10592
aorta1.52e-0921
aortic system1.52e-0921
blood vessel smooth muscle3.09e-0810
arterial system smooth muscle3.09e-0810
artery smooth muscle tissue3.09e-0810
aorta smooth muscle tissue3.09e-0810
anatomical conduit8.05e-08240
tube1.31e-07192
vasculature of organ3.40e-0711
Disease
Ontology termp-valuen
ovarian cancer3.90e-0814


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0471418
MA0004.10.826076
MA0006.10.639288
MA0007.10.804807
MA0009.11.3275
MA0014.10.118426
MA0017.10.686276
MA0019.10.990656
MA0024.11.21731
MA0025.11.46617
MA0027.12.95767
MA0028.10.658629
MA0029.11.23771
MA0030.11.22561
MA0031.11.15713
MA0038.10.94098
MA0040.11.24388
MA0041.10.847069
MA0042.10.810843
MA0043.11.32783
MA0046.11.31611
MA0048.11.62115
MA0050.10.81185
MA0051.10.936307
MA0052.11.24796
MA0055.11.06172
MA0056.10
MA0057.10.333427
MA0058.10.716037
MA0059.10.714521
MA0060.12.13518
MA0061.10.456531
MA0063.10
MA0066.10.941452
MA0067.11.65513
MA0068.10.405474
MA0069.11.31207
MA0070.11.30033
MA0071.10.897953
MA0072.11.29561
MA0073.10.407479
MA0074.10.935474
MA0076.10.734647
MA0077.11.28751
MA0078.11.04495
MA0081.10.714712
MA0083.11.33535
MA0084.11.84562
MA0087.11.29304
MA0088.10.257905
MA0089.10
MA0090.10.751469
MA0091.10.829044
MA0092.10.785956
MA0093.10.642957
MA0095.10
MA0098.10
MA0100.10.956299
MA0101.10.646932
MA0103.10.628063
MA0105.10.31555
MA0106.10.986396
MA0107.10.556367
MA0108.21.15387
MA0109.10
MA0111.10.767139
MA0113.11.00436
MA0114.10.549955
MA0115.11.57693
MA0116.10.560723
MA0117.11.36676
MA0119.12.7939
MA0122.11.39371
MA0124.11.53432
MA0125.11.44766
MA0130.10
MA0131.11.06461
MA0132.10
MA0133.10
MA0135.11.35921
MA0136.10.948776
MA0139.10.440097
MA0140.10.894983
MA0141.10.712476
MA0142.11.12317
MA0143.11.00455
MA0144.10.531867
MA0145.10.752137
MA0146.10.107247
MA0147.10.565108
MA0148.10.854239
MA0149.10.884158
MA0062.20.449458
MA0035.20.894194
MA0039.20.0526989
MA0138.21.04628
MA0002.20.476938
MA0137.20.666381
MA0104.20.491226
MA0047.20.973066
MA0112.20.264678
MA0065.20.277623
MA0150.10.744617
MA0151.10
MA0152.10.902317
MA0153.11.43021
MA0154.10.312019
MA0155.10.256269
MA0156.10.669101
MA0157.11.09377
MA0158.10
MA0159.10.565904
MA0160.10.871361
MA0161.10
MA0162.10.149099
MA0163.10.122425
MA0164.11.01792
MA0080.21.55139
MA0018.20.987913
MA0099.20.902716
MA0079.20.181755
MA0102.21.88331
MA0258.10.519674
MA0259.10.575594
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.