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Coexpression cluster:C4178: Difference between revisions

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|ontology_enrichment_celltype=
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!1.56e-44!115;UBERON:0001049!2.04e-44!57;UBERON:0005068!2.04e-44!57;UBERON:0006241!2.04e-44!57;UBERON:0007135!2.04e-44!57;UBERON:0003075!1.52e-39!86;UBERON:0007284!1.52e-39!86;UBERON:0002346!1.93e-39!90;UBERON:0003080!4.29e-38!42;UBERON:0005743!1.46e-37!86;UBERON:0002780!2.37e-37!41;UBERON:0001890!2.37e-37!41;UBERON:0006240!2.37e-37!41;UBERON:0001017!2.08e-36!82;UBERON:0002616!2.10e-36!59;UBERON:0000073!1.87e-34!94;UBERON:0001016!1.87e-34!94;UBERON:0000955!1.71e-31!69;UBERON:0006238!1.71e-31!69;UBERON:0002020!6.99e-31!34;UBERON:0003528!6.99e-31!34;UBERON:0001893!1.78e-30!34;UBERON:0002791!1.39e-29!33;UBERON:0003056!9.16e-29!61;UBERON:0001869!1.49e-28!32;UBERON:0000924!9.28e-25!173;UBERON:0006601!9.28e-25!173;UBERON:0004121!2.48e-24!169;UBERON:0000033!3.30e-22!123;UBERON:0000153!4.40e-22!129;UBERON:0007811!4.40e-22!129;UBERON:0002619!6.23e-22!22;UBERON:0000956!9.50e-22!25;UBERON:0000203!9.50e-22!25;UBERON:0001950!1.11e-19!20;UBERON:0000025!2.29e-12!194;UBERON:0002308!1.29e-10!9;UBERON:0000125!1.29e-10!9;UBERON:0004111!1.41e-10!241;UBERON:0002420!1.51e-10!9;UBERON:0007245!1.51e-10!9;UBERON:0010009!1.51e-10!9;UBERON:0010011!1.51e-10!9;UBERON:0000454!1.51e-10!9;UBERON:0001871!1.75e-09!7;UBERON:0002298!3.64e-09!8;UBERON:0000477!4.78e-09!286;UBERON:0009663!1.56e-08!7;UBERON:0000062!2.22e-08!511;UBERON:0001894!3.13e-08!7;UBERON:0006222!3.13e-08!7;UBERON:0003076!5.61e-08!15;UBERON:0003057!5.61e-08!15;UBERON:0000483!1.12e-07!309;UBERON:0000119!2.20e-07!312;UBERON:0000475!2.85e-07!365;UBERON:0000200!2.98e-07!6;UBERON:0000064!5.26e-07!219;UBERON:0000349!8.97e-07!5
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}}
}}

Revision as of 15:44, 19 October 2012


Full id: C4178_temporal_parietal_duodenum_occipital_adrenal_seminal_rhabdomyosarcoma



Phase1 CAGE Peaks

Hg19::chr2:212842252..212842257,-p@chr2:212842252..212842257
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Hg19::chr2:213296026..213296031,-p@chr2:213296026..213296031
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Hg19::chr2:213315541..213315545,-p@chr2:213315541..213315545
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.60e-5856
neural rod1.60e-5856
future spinal cord1.60e-5856
neural keel1.60e-5856
regional part of nervous system5.90e-5453
regional part of brain5.90e-5453
adult organism1.12e-46114
regional part of forebrain1.56e-4641
forebrain1.56e-4641
anterior neural tube1.56e-4641
future forebrain1.56e-4641
neural plate3.28e-4382
presumptive neural plate3.28e-4382
neurectoderm2.50e-4286
brain grey matter1.51e-4134
gray matter1.51e-4134
telencephalon3.57e-4134
brain2.26e-3868
future brain2.26e-3868
regional part of telencephalon2.80e-3832
cerebral hemisphere4.48e-3832
central nervous system3.29e-3781
ecto-epithelium1.32e-35104
nervous system1.04e-3389
regional part of cerebral cortex1.02e-3122
cerebral cortex8.71e-3025
pallium8.71e-3025
pre-chordal neural plate1.88e-2961
structure with developmental contribution from neural crest1.37e-28132
neocortex4.14e-2820
ectoderm-derived structure8.20e-22171
ectoderm8.20e-22171
presumptive ectoderm8.20e-22171
tube1.28e-14192
organ system subdivision1.13e-13223
neural nucleus4.25e-139
nucleus of brain4.25e-139
posterior neural tube7.30e-1315
chordal neural plate7.30e-1315
anatomical conduit8.92e-13240
brainstem8.96e-116
gyrus1.23e-106
basal ganglion3.27e-109
nuclear complex of neuraxis3.27e-109
aggregate regional part of brain3.27e-109
collection of basal ganglia3.27e-109
cerebral subcortex3.27e-109
telencephalic nucleus6.75e-107
anatomical cluster6.81e-10373
temporal lobe1.29e-096
parietal lobe4.52e-095
segmental subdivision of hindbrain7.00e-0912
hindbrain7.00e-0912
presumptive hindbrain7.00e-0912
multi-tissue structure8.16e-09342
organ part1.97e-08218
corpus striatum3.72e-084
striatum3.72e-084
ventral part of telencephalon3.72e-084
future corpus striatum3.72e-084
segmental subdivision of nervous system4.52e-0813
epithelium8.62e-08306
cell layer1.43e-07309
caudate-putamen7.37e-073
dorsal striatum7.37e-073
diencephalon7.62e-077
future diencephalon7.62e-077


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.