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{{Coexpression_clusters
{{Coexpression_clusters
|coexpression_dpi_cluster_scores_median=0.0724992894770213,0.0842546465117019,0,0,0.160456854061196,0.27238437317198,0,0,0,0.0954252957357428,0,0.988454378537434,1.0724133655661,0.0960519401186186,0.220838645003429,0,0,0,0,0.0504265701716883,0.305352112524117,0.211363379907382,0,0,0,0,0,0,0,0,0.117149360021774,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.156712528252229,0,0,0.0392295810357272,0,0.0365629421359175,0.0534545700183436,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.400291723212574,0.649048046595295,0,0,0,0,0,0,0,0,0,0,0.340047884800798,0.39508192670348,0,0,0.067567801197968,0.0511982733942606,0,0.158054039799331,0,0.161581855097325,0,0,0,0,0,0,0,0,0,0,0,0,0.0650738225586148,0,0,0,0,0,0,0,0,0.258483456842414,0.150647229477047,0.0977156115525172,0,0,0,0,0.521378663312653,0,0,0,0,0,0,0,0,0,0,0,0,0,0.392712270020621,0,0,0.201612826790636,0,0.93577336295613,0,0,0,0,0.106451101971206,0,0,0,0.0476371106609188,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.438358826582664,0.0307366208579214,0,0,0,0.185223678206009,0,0.0994069197460863,0,0.102578507776567,0.234236259832332,1.17921162551282,0.260843920469556,0,0.132064901528981,0.253326341486756,0,0,0,0,0,0,0,0,0,0.110442433690542,0.20855662473171,0.0715362608323278,0,0,0,0,0,0,0,0,0,0,0,0,0.393100800075624,0.30110404570588,0.258588217388716,0.351762529756912,0.27695440160179,0.212403275340347,0.287159062945695,0,0,0.308506940524756,0,0,0,1.20087478199912,1.39828799388823,0,0,0,0.636929316927636,0.884082331033755,1.23113011543345,0,0.0620032815069762,0,0,0,0.0647775726819609,0,0,0,0,0,0,1.05204155712578,0.0793645050922885,0.0382548469252227,0.0897740605496476,0.0726509725142573,0.183126762043246,0,0.0622173525481225,0,0,0,0,0,0.0849035433286077,0.405222104277016,0.104127248139133,0.176580223334895,0,0,0,0,0,0,0,0,0.405792751191455,0,0,0,0,0,0.110593802369687,0,0.0620189823948138,0.150298798479565,0,0.110600950579883,0.0988789363017444,0.743559448466315,0.066432124538699,0.141255358724553,0,0.0800184682686384,0,0,0,0,0,0,0,0,0,0.21292204628454,0.246134244935293,0.0989542966657617,0.358661294553704,0,0,0.18741280294663,0.105352457754613,0.091886618011139,0,0,0,0.295625913345657,0,0,0.291257682561122,0,0,0,0,0,0,0,0,0,0,0.0582024997333375,0.2012589601207,0,0,0,0,0,0.130312767515111,0,0,0,0.445406813571861,0.360122916322148,0,0.367410057325623,0.416318211399681,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.158219072164516,0,0,0.108611070985339,1.28204586215198,1.09973665224964,1.49278480945523,0,0,0,0,0.152976191689497,0.145661221236375,0,0.0975809997847489,0,0,0,0,0,0,0.144441446549164,0,0,0,0.0385280079017836,0,0,0,0.236788992518656,0,0,0,0,0,0,0,0,0,0.0455495587624001,0,0.0861409897892114,0,0,0.208334400411299,0,0.454007653461232,0,0,1.3371611507693,0.529114198763773,1.96197090882382,0,0,0,0,0,0,0,0,0,0,0.298737722087551,0,0,0.0368115019473605,0.452260437813108,0,0,0,0.0549201943193819,1.27083501995363,0,0,0,0,0,0.848160520526284,0.115967372264001,0.289544070398355,0,0,0,0,0,0,0,0,0,0,0,0.346956396082,0,0,0,0,0.0769963366386578,0,0.642435940123811,0,0,0,0,0,0.0840229578243582,0.698639136300262,0,0,1.39535618452338,0,0,0,0,0,0,0,0,0,0,0,0,0.192724864233909,0.163853084473343,0.234991060098501,0.25496259830806,0.155100922768919,0,0.498292784519009,0,0,0.974502505072354,0.953969216674239,0.995515321058593,0.786625730970128,0,0,0,0,0,0,0,0,0,0,0.0635628004819691,0.363868476922976,0.0435981622194311,0,0,0.385497356176373,0.220655051407841,0,0,0,0,0,0,0,0.088711522602743,0.111633612091231,1.41790840691,0,0,0,0,0,0.118730395337086,0,0,0,0,0,0,0,0,0,0,0,0,0,0.196841684047034,0.0456863240084368,0.0508408017580101,0,0,0,0,0.0917604244830311,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.145536958608929,0.477141350988027,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.195211969605328,0,0,0.210071535945973,0,0,0,0.123076702386819,0,0,0,0,0,0,0,0.231814006190654,0.116024799788948,0,0,0,0,0.0976291981890722,0,0.0650101077405693,0,0,0,0,0,0,0,0.413522685539832,0.204576464877444,0,0,0,0,0,0.0283831740999027,0,0,0.0267031128419265,0.189483241693255,0,0.174992895090299,0,0,0,0,0.206006581150341,0.0890788809625826,0.888818393555795,0,0,0.0285589446518912,0,0,0,0.118586233508558,0,0.471571145864469,0.572810769020978,0,0,0.251940293321241,0,0,0.97058846416735,0,0,0,0,0,0,0,0,0.0895896456213401,0,0,0,0,0.172507101478514,0.216806663761278,0.179929059684616,1.61902552003007,0.730087408926382,0,0.878830493286347,0,0,0,0,0,0.439092025493499,0,0.0952210875623146,0.0919048039302623,0.201103507940666,0,0.493217991705455,0,0,0.141997337698646,0,0,0,0,0.503928051510997,0,0.0581752393062885,0.168295518090842,0,0.157260487458867,0.718685558632018,0,0,0.156132999089005,0,0,0,0,0,0,0,0.225828130386425,0.103106967823645,0,0,0.0839445661171913,0.947243798499374,0.0271819376754428,0.175105077624543,0,0.0267975841371139,0.534712088023823,0.218312325465419,1.52074455896351,0.0283076897745917,0.0582150559773052,0.984489925064033,0.172725383723956,0,0,0.432436727776634,1.10489823723715,0.094988929438441,0.628916856909537,0,0.146917605400546,0
|full_id=C172_chorionic_skeletal_tongue_amniotic_liver_gastrointestinal_Pericytes
|full_id=C172_chorionic_skeletal_tongue_amniotic_liver_gastrointestinal_Pericytes
|gostat_on_coexpression_clusters=GO:0006349!genetic imprinting!0.00323796067349582!3481$GO:0018445!prothoracicotrophic hormone activity!0.00323796067349582!3481$GO:0005159!insulin-like growth factor receptor binding!0.00323796067349582!3481$GO:0008286!insulin receptor signaling pathway!0.00582832921229247!3481$GO:0005184!neuropeptide hormone activity!0.00582832921229247!3481$GO:0040029!regulation of gene expression, epigenetic!0.00956670198987401!3481$GO:0001501!skeletal development!0.0212920444287452!3481$GO:0007169!transmembrane receptor protein tyrosine kinase signaling pathway!0.0212920444287452!3481$GO:0005179!hormone activity!0.0212920444287452!3481$GO:0008083!growth factor activity!0.0223419286471212!3481$GO:0007167!enzyme linked receptor protein signaling pathway!0.024084005009473!3481
|gostat_on_coexpression_clusters=GO:0006349!genetic imprinting!0.00323796067349582!3481$GO:0018445!prothoracicotrophic hormone activity!0.00323796067349582!3481$GO:0005159!insulin-like growth factor receptor binding!0.00323796067349582!3481$GO:0008286!insulin receptor signaling pathway!0.00582832921229247!3481$GO:0005184!neuropeptide hormone activity!0.00582832921229247!3481$GO:0040029!regulation of gene expression, epigenetic!0.00956670198987401!3481$GO:0001501!skeletal development!0.0212920444287452!3481$GO:0007169!transmembrane receptor protein tyrosine kinase signaling pathway!0.0212920444287452!3481$GO:0005179!hormone activity!0.0212920444287452!3481$GO:0008083!growth factor activity!0.0223419286471212!3481$GO:0007167!enzyme linked receptor protein signaling pathway!0.024084005009473!3481

Revision as of 14:20, 12 September 2012


Full id: C172_chorionic_skeletal_tongue_amniotic_liver_gastrointestinal_Pericytes



Phase1 CAGE Peaks

Hg19::chr11:2150745..2150785,+p1@BC127839
Hg19::chr11:2151798..2151813,-p2@IGF2
Hg19::chr11:2151877..2151902,+p@chr11:2151877..2151902
+
Hg19::chr11:2151947..2151958,+p@chr11:2151947..2151958
+
Hg19::chr11:2152575..2152590,+p@chr11:2152575..2152590
+
Hg19::chr11:2152641..2152652,+p@chr11:2152641..2152652
+
Hg19::chr11:2152665..2152693,+p27@IGF2
Hg19::chr11:2152702..2152747,+p17@IGF2
Hg19::chr11:2152775..2152817,+p14@IGF2
Hg19::chr11:2152829..2152834,+p57@IGF2
Hg19::chr11:2152856..2152896,+p21@IGF2
Hg19::chr11:2152902..2152970,+p13@IGF2
Hg19::chr11:2152974..2153103,+p10@IGF2
Hg19::chr11:2153071..2153082,-p8@IGF2
Hg19::chr11:2153108..2153139,+p29@IGF2
Hg19::chr11:2153157..2153189,+p26@IGF2
Hg19::chr11:2153165..2153178,-p11@IGF2
Hg19::chr11:2153201..2153247,+p18@IGF2
Hg19::chr11:2153253..2153337,+p15@IGF2
Hg19::chr11:2153332..2153354,-p6@IGF2
Hg19::chr11:2153356..2153374,-p7@IGF2
Hg19::chr11:2153389..2153416,-p4@IGF2
Hg19::chr11:2153449..2153463,-p5@IGF2
Hg19::chr11:2153576..2153579,-p@chr11:2153576..2153579
-
Hg19::chr11:2153590..2153601,-p@chr11:2153590..2153601
-
Hg19::chr11:2153605..2153619,-p@chr11:2153605..2153619
-
Hg19::chr11:2153817..2153828,+p3@BC075845
Hg19::chr11:2153850..2153861,+p2@BC075845
Hg19::chr11:2153890..2153941,+p1@BC075845
p2@BC021076
Hg19::chr11:2153950..2153990,+p1@BC021076
Hg19::chr11:2154002..2154014,+p3@BC021076
Hg19::chr11:2154041..2154052,+p4@BC021076
Hg19::chr11:2154088..2154099,+p5@CU674261
Hg19::chr11:2154095..2154106,-p@chr11:2154095..2154106
-
Hg19::chr11:2154106..2154118,+p3@CU674261
Hg19::chr11:2154122..2154138,+p4@CU674261
Hg19::chr11:2154145..2154155,+p7@CU674261
Hg19::chr11:2154203..2154221,+p2@CU674261
Hg19::chr11:2154248..2154285,+p1@CU674261
Hg19::chr11:2154382..2154391,+p6@CU674261
Hg19::chr11:2154762..2154797,+p@chr11:2154762..2154797
+
Hg19::chr11:2154767..2154781,-p36@IGF2
Hg19::chr11:2154790..2154814,-p24@IGF2
Hg19::chr11:2154832..2154852,-p44@IGF2
Hg19::chr11:2154872..2154893,-p38@IGF2
Hg19::chr11:2156633..2156657,-p32@IGF2
Hg19::chr11:2156660..2156669,-p64@IGF2
Hg19::chr11:2156671..2156708,-p40@IGF2
Hg19::chr11:2156713..2156749,-p37@IGF2
Hg19::chr11:2156751..2156773,-p55@IGF2
Hg19::chr11:2159479..2159489,-p54@IGF2
Hg19::chr11:2159491..2159532,-p23@IGF2
Hg19::chr11:2159538..2159595,-p12@IGF2
Hg19::chr11:2159572..2159583,+p20@BC017277
Hg19::chr11:2159607..2159615,-p1@X06260
Hg19::chr11:2159622..2159637,+p8@BC017277
Hg19::chr11:2159650..2159672,+p9@BC017277
Hg19::chr11:2159658..2159696,-p28@IGF2
Hg19::chr11:2159675..2159689,+p11@BC017277
Hg19::chr11:2159697..2159702,-p58@IGF2
Hg19::chr11:2159700..2159730,+p6@BC017277
Hg19::chr11:2159738..2159755,-p43@IGF2
Hg19::chr11:2159748..2159761,+p12@BC017277
Hg19::chr11:2159760..2159769,-p42@IGF2
Hg19::chr11:2159773..2159793,-p33@IGF2
Hg19::chr11:2159808..2159810,-p62@IGF2
Hg19::chr11:2159814..2159825,+p14@BC017277
Hg19::chr11:2159824..2159832,-p39@IGF2
Hg19::chr11:2159834..2159900,-p9@IGF2
Hg19::chr11:2159838..2159847,+p16@BC017277
Hg19::chr11:2159872..2159877,+p18@BC017277
Hg19::chr11:2159911..2159935,-p22@IGF2
Hg19::chr11:2159935..2159950,+p5@BC017277
Hg19::chr11:2159947..2159948,-p71@IGF2
Hg19::chr11:2159954..2159960,-p46@IGF2
Hg19::chr11:2159969..2159986,+p2@BC017277
Hg19::chr11:2159997..2160004,+p15@BC017277
Hg19::chr11:2160010..2160024,+p10@BC017277
Hg19::chr11:2160019..2160028,-p48@IGF2
Hg19::chr11:2160036..2160049,+p7@BC017277
Hg19::chr11:2160043..2160076,-p25@IGF2
Hg19::chr11:2160078..2160088,-p52@IGF2
Hg19::chr11:2160094..2160100,-p53@IGF2
Hg19::chr11:2160098..2160115,+p4@BC017277
Hg19::chr11:2160117..2160121,-p30@IGF2
Hg19::chr11:2160161..2160172,-p34@IGF2
Hg19::chr11:2160180..2160257,-p19@IGF2
Hg19::chr11:2160283..2160292,+p19@BC017277
Hg19::chr11:2160293..2160310,+p3@BC017277
Hg19::chr11:2160337..2160349,+p13@BC017277
Hg19::chr11:2160354..2160387,+p1@BC017277
Hg19::chr11:2160369..2160383,-p20@IGF2
Hg19::chr11:2160430..2160435,-p41@IGF2
Hg19::chr11:2160468..2160486,-p35@IGF2
Hg19::chr11:2160485..2160488,+p21@BC017277
Hg19::chr11:2160500..2160515,-p47@IGF2
Hg19::chr11:2160520..2160531,-p50@IGF2
Hg19::chr11:2160538..2160549,-p45@IGF2
Hg19::chr11:2160567..2160571,-p51@IGF2
Hg19::chr11:2160611..2160656,-p1@IGF2
Hg19::chr11:2162486..2162497,-p56@IGF2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006349genetic imprinting0.00323796067349582
GO:0018445prothoracicotrophic hormone activity0.00323796067349582
GO:0005159insulin-like growth factor receptor binding0.00323796067349582
GO:0008286insulin receptor signaling pathway0.00582832921229247
GO:0005184neuropeptide hormone activity0.00582832921229247
GO:0040029regulation of gene expression, epigenetic0.00956670198987401
GO:0001501skeletal development0.0212920444287452
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway0.0212920444287452
GO:0005179hormone activity0.0212920444287452
GO:0008083growth factor activity0.0223419286471212
GO:0007167enzyme linked receptor protein signaling pathway0.024084005009473



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
multi-cellular organism7.26e-23659
multi-tissue structure1.74e-19347
adult organism1.38e-18115
embryo1.47e-17612
organism subdivision2.23e-17365
anatomical system4.76e-16625
anatomical group1.06e-15626
embryonic structure1.73e-15605
developing anatomical structure1.73e-15605
cell layer1.90e-15312
germ layer4.58e-15604
embryonic tissue4.58e-15604
presumptive structure4.58e-15604
epiblast (generic)4.58e-15604
epithelium7.64e-15309
organ4.29e-13511
organ part1.42e-12219
anatomical cluster6.25e-12286
endoderm-derived structure1.87e-10169
endoderm1.87e-10169
presumptive endoderm1.87e-10169
trunk2.18e-10216
anatomical conduit4.47e-10241
extraembryonic membrane7.10e-1014
membranous layer7.10e-1014
ectoderm-derived structure2.99e-09169
anterior region of body6.85e-09129
craniocervical region6.85e-09129
regional part of brain7.92e-0959
mesenchyme8.06e-09238
entire embryonic mesenchyme8.06e-09238
trunk mesenchyme8.54e-09143
neural plate8.70e-0986
presumptive neural plate8.70e-0986
ectoderm9.56e-09173
presumptive ectoderm9.56e-09173
head1.18e-08123
central nervous system2.03e-0882
neural tube4.42e-0857
neural rod4.42e-0857
future spinal cord4.42e-0857
neural keel4.42e-0857
neurectoderm4.88e-0890
immaterial anatomical entity6.87e-08126
tube8.27e-08194
brain8.41e-0869
future brain8.41e-0869
trunk region element1.13e-07107
digestive system1.56e-07155
digestive tract1.56e-07155
primitive gut1.56e-07155
regional part of nervous system1.69e-0794
nervous system1.69e-0794
subdivision of digestive tract1.91e-07129
endodermal part of digestive tract1.91e-07129
renal system2.85e-0745
urinary system structure5.44e-0744
abdominal segment of trunk6.39e-0761
abdomen6.39e-0761
extraembryonic structure7.65e-0724
mixed endoderm/mesoderm-derived structure8.32e-07130


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
FOSL2#2355162.682011976960270.0002844783653761130.00302613933606802
HEY1#23462873.480095650992051.67519531429499e-389.15998551987718e-36



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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