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Coexpression cluster:C3325

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Full id: C3325_Mesenchymal_cerebellum_Cardiac_large_brain_vagina_pineal



Phase1 CAGE Peaks

Hg19::chr12:7036797..7036884,+p@chr12:7036797..7036884
+
Hg19::chr12:7036941..7036986,+p1@ATN1
Hg19::chr12:7036987..7037005,+p2@ATN1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism8.27e-33115
neural tube3.20e-3057
neural rod3.20e-3057
future spinal cord3.20e-3057
neural keel3.20e-3057
organism subdivision9.30e-30365
anatomical conduit1.78e-28241
neurectoderm3.32e-2890
tube5.64e-28194
neural plate5.83e-2886
presumptive neural plate5.83e-2886
cell layer8.32e-28312
multi-tissue structure9.15e-28347
epithelium1.62e-27309
central nervous system4.94e-2782
anatomical cluster5.88e-27286
regional part of brain1.88e-2659
regional part of nervous system5.16e-2694
nervous system5.16e-2694
brain5.53e-2669
future brain5.53e-2669
ectoderm1.75e-24173
presumptive ectoderm1.75e-24173
ectoderm-derived structure5.71e-24169
head4.23e-23123
anterior neural tube5.31e-2242
regional part of forebrain2.28e-2141
forebrain2.28e-2141
future forebrain2.28e-2141
anterior region of body3.74e-21129
craniocervical region3.74e-21129
multi-cellular organism1.30e-19659
pre-chordal neural plate1.62e-1961
gray matter6.14e-1834
brain grey matter6.14e-1834
telencephalon6.51e-1834
regional part of telencephalon2.53e-1733
cerebral hemisphere8.29e-1732
embryo9.77e-17612
organ part3.14e-16219
anatomical system2.55e-15625
anatomical group3.90e-15626
embryonic structure3.91e-15605
developing anatomical structure3.91e-15605
germ layer7.84e-15604
embryonic tissue7.84e-15604
presumptive structure7.84e-15604
epiblast (generic)7.84e-15604
regional part of cerebral cortex6.15e-1422
cerebral cortex1.46e-1325
pallium1.46e-1325
neocortex7.41e-1320
organ4.39e-10511
posterior neural tube2.55e-0915
chordal neural plate2.55e-0915
compound organ2.56e-0869
segmental subdivision of nervous system2.60e-0813
trunk4.38e-08216
segmental subdivision of hindbrain6.59e-0812
hindbrain6.59e-0812
presumptive hindbrain6.59e-0812


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.