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Coexpression cluster:C935

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Full id: C935_Small_Mallassezderived_Gingival_normal_mucinous_Urothelial_Prostate



Phase1 CAGE Peaks

Hg19::chr1:94995089..94995168,-p@chr1:94995089..94995168
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Hg19::chr1:94995218..94995229,-p@chr1:94995218..94995229
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Hg19::chr1:94995248..94995299,-p@chr1:94995248..94995299
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Hg19::chr1:94995320..94995336,-p@chr1:94995320..94995336
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Hg19::chr1:94995771..94995826,-p@chr1:94995771..94995826
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Hg19::chr1:94996033..94996059,-p@chr1:94996033..94996059
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Hg19::chr1:94996081..94996103,-p@chr1:94996081..94996103
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Hg19::chr1:95005908..95005937,-p@chr1:95005908..95005937
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Hg19::chr1:95007302..95007322,-p1@F3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
endo-epithelial cell1.27e-1143
endodermal cell1.50e-0759
epithelial cell3.17e-07254
respiratory epithelial cell5.81e-0713
Uber Anatomy
Ontology termp-valuen
organ1.95e-25511
multi-cellular organism1.49e-22659
anatomical system1.92e-22625
anatomical group3.50e-22626
organism subdivision1.11e-16365
embryonic structure6.48e-16605
developing anatomical structure6.48e-16605
embryo7.30e-16612
germ layer1.28e-15604
embryonic tissue1.28e-15604
presumptive structure1.28e-15604
epiblast (generic)1.28e-15604
organ part4.33e-13219
ectoderm-derived structure2.05e-12169
head5.34e-12123
ectoderm5.69e-11173
presumptive ectoderm5.69e-11173
anterior region of body9.19e-11129
craniocervical region9.19e-11129
neural plate1.43e-1086
presumptive neural plate1.43e-1086
cell layer1.66e-10312
epithelium1.99e-10309
multi-tissue structure6.98e-10347
neural tube1.03e-0957
neural rod1.03e-0957
future spinal cord1.03e-0957
neural keel1.03e-0957
regional part of brain1.13e-0959
pre-chordal neural plate6.08e-0961
central nervous system7.83e-0982
neurectoderm9.48e-0990
brain2.03e-0869
future brain2.03e-0869
anterior neural tube7.45e-0842
regional part of nervous system1.01e-0794
nervous system1.01e-0794
regional part of forebrain1.61e-0741
forebrain1.61e-0741
future forebrain1.61e-0741
gray matter3.13e-0734
brain grey matter3.13e-0734
anatomical conduit3.63e-07241
anatomical cluster4.91e-07286
endoderm-derived structure7.17e-07169
endoderm7.17e-07169
presumptive endoderm7.17e-07169
surface structure8.42e-0795


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.