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MCL coexpression mm9:666

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:85023868..85023879,+p@chr12:85023868..85023879
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Mm9::chr2:164317532..164317534,+p@chr2:164317532..164317534
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Mm9::chr2:180764007..180764024,-p@chr2:180764007..180764024
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Mm9::chr2:31139664..31139677,+p@chr2:31139664..31139677
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Mm9::chr2:90730407..90730420,+p@chr2:90730407..90730420
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Mm9::chr3:88548978..88548990,-p@chr3:88548978..88548990
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Mm9::chr5:136386450..136386468,-p@chr5:136386450..136386468
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Mm9::chr7:148613898..148613907,-p@chr7:148613898..148613907
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Mm9::chr8:67071668..67071696,-p@chr8:67071668..67071696
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Mm9::chr8:67087900..67087910,-p@chr8:67087900..67087910
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Mm9::chrX:7218219..7218235,+p@chrX:7218219..7218235
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004183carboxypeptidase E activity0.00304059606640004
GO:0030070insulin processing0.00304059606640004
GO:0016486peptide hormone processing0.0141847842229041
GO:0004182carboxypeptidase A activity0.0364292092115519
GO:0004181metallocarboxypeptidase activity0.0364292092115519
GO:0004180carboxypeptidase activity0.0424727922720623
GO:0008235metalloexopeptidase activity0.0476395688666937
GO:0016485protein processing0.0499913764335937



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of nervous system1.15e-4454
central nervous system3.37e-4273
gray matter4.16e-4134
nervous system9.01e-4175
neural tube1.24e-4052
neural rod1.24e-4052
future spinal cord1.24e-4052
neural keel1.24e-4052
neurectoderm1.19e-3464
neural plate1.19e-3464
presumptive neural plate1.19e-3464
ectoderm-derived structure9.07e-3395
ectoderm9.07e-3395
presumptive ectoderm9.07e-3395
brain grey matter2.79e-3229
regional part of telencephalon2.79e-3229
telencephalon2.79e-3229
regional part of brain6.33e-3146
brain4.44e-3047
future brain4.44e-3047
ecto-epithelium4.32e-2973
anterior neural tube9.20e-2840
regional part of forebrain1.83e-2639
forebrain1.83e-2639
future forebrain1.83e-2639
pre-chordal neural plate1.76e-2449
structure with developmental contribution from neural crest6.14e-2192
cerebral cortex3.48e-2021
cerebral hemisphere3.48e-2021
pallium3.48e-2021
occipital lobe9.78e-1810
visual cortex9.78e-1810
neocortex9.78e-1810
regional part of cerebral cortex1.40e-1717
basal ganglion2.16e-138
nuclear complex of neuraxis2.16e-138
aggregate regional part of brain2.16e-138
collection of basal ganglia2.16e-138
cerebral subcortex2.16e-138
tube4.28e-13114
posterior neural tube6.60e-1312
chordal neural plate6.60e-1312
anatomical conduit1.34e-11122
spinal cord2.54e-116
dorsal region element2.54e-116
dorsum2.54e-116
regional part of spinal cord5.68e-105
gray matter of spinal cord5.68e-105
organ part6.43e-0999
organ system subdivision8.66e-09194
corpus striatum2.36e-085
striatum2.36e-085
ventral part of telencephalon2.36e-085
future corpus striatum2.36e-085
regional part of midbrain6.49e-084
midbrain6.49e-084
presumptive midbrain6.49e-084
midbrain neural tube6.49e-084
raphe nuclei4.47e-073
reticular formation4.47e-073


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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