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Coexpression cluster:C156

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Full id: C156_plasma_splenic_hereditary_B_large_xeroderma_b



Phase1 CAGE Peaks

Hg19::chr10:56410468..56410499,-p@chr10:56410468..56410499
-
Hg19::chr10:92426203..92426205,-p@chr10:92426203..92426205
-
Hg19::chr11:26501062..26501069,-p@chr11:26501062..26501069
-
Hg19::chr11:41501367..41501373,+p@chr11:41501367..41501373
+
Hg19::chr12:10205220..10205239,+p4@AB590792
Hg19::chr12:10205256..10205285,+p2@AB590792
Hg19::chr12:39008217..39008221,+p@chr12:39008217..39008221
+
Hg19::chr12:40953908..40953923,+p@chr12:40953908..40953923
+
Hg19::chr12:40953942..40953946,+p@chr12:40953942..40953946
+
Hg19::chr12:40953952..40953977,+p@chr12:40953952..40953977
+
Hg19::chr12:40953998..40954021,+p@chr12:40953998..40954021
+
Hg19::chr12:40991131..40991149,+p@chr12:40991131..40991149
+
Hg19::chr14:106589870..106589873,-p@chr14:106589870..106589873
-
Hg19::chr14:106829914..106829921,-p1@HM996258
p1@HM996415
p1@HM996438
Hg19::chr14:107160349..107160365,-p1@IGHV1-68
Hg19::chr14:22942233..22942253,+p2@uc001wec.2
Hg19::chr14:54342069..54342074,-p@chr14:54342069..54342074
-
Hg19::chr17:25546162..25546166,+p@chr17:25546162..25546166
+
Hg19::chr17:76471146..76471155,+p@chr17:76471146..76471155
+
Hg19::chr17:76471163..76471166,+p@chr17:76471163..76471166
+
Hg19::chr17:76473890..76473895,+p@chr17:76473890..76473895
+
Hg19::chr17:76475138..76475154,-p@chr17:76475138..76475154
-
Hg19::chr17:76475275..76475285,-p@chr17:76475275..76475285
-
Hg19::chr17:76480917..76480935,+p@chr17:76480917..76480935
+
Hg19::chr17:76480937..76480971,+p@chr17:76480937..76480971
+
Hg19::chr17:76480973..76481009,+p@chr17:76480973..76481009
+
Hg19::chr17:76483088..76483092,+p@chr17:76483088..76483092
+
Hg19::chr18:28728570..28728577,-p@chr18:28728570..28728577
-
Hg19::chr18:28728597..28728607,-p@chr18:28728597..28728607
-
Hg19::chr18:67696064..67696069,-p@chr18:67696064..67696069
-
Hg19::chr19:42041721..42041734,+p8@CEACAM21
Hg19::chr1:101853882..101853891,-p@chr1:101853882..101853891
-
Hg19::chr1:17349613..17349631,-p8@SDHB
Hg19::chr1:17349654..17349690,-p6@SDHB
Hg19::chr1:233621292..233621303,-p@chr1:233621292..233621303
-
Hg19::chr1:75045223..75045244,-p13@C1orf173
Hg19::chr1:75045269..75045282,-p19@C1orf173
Hg19::chr1:91072926..91072932,-p@chr1:91072926..91072932
-
Hg19::chr21:16209394..16209398,-p@chr21:16209394..16209398
-
Hg19::chr21:20740945..20740987,-p@chr21:20740945..20740987
-
Hg19::chr21:20741173..20741184,-p@chr21:20741173..20741184
-
Hg19::chr21:20741243..20741260,-p@chr21:20741243..20741260
-
Hg19::chr21:20741370..20741383,-p@chr21:20741370..20741383
-
Hg19::chr21:20747453..20747465,-p@chr21:20747453..20747465
-
Hg19::chr21:20752389..20752420,-p@chr21:20752389..20752420
-
Hg19::chr21:20752617..20752622,-p@chr21:20752617..20752622
-
Hg19::chr21:20752643..20752654,-p@chr21:20752643..20752654
-
Hg19::chr21:20752678..20752693,-p@chr21:20752678..20752693
-
Hg19::chr21:20867728..20867731,-p@chr21:20867728..20867731
-
Hg19::chr2:101054417..101054453,+p@chr2:101054417..101054453
+
Hg19::chr2:151428755..151428762,-p1@ENST00000441356
Hg19::chr2:157336503..157336506,-p@chr2:157336503..157336506
-
Hg19::chr2:197274224..197274231,-p@chr2:197274224..197274231
-
Hg19::chr2:197274235..197274251,-p@chr2:197274235..197274251
-
Hg19::chr2:197274253..197274273,-p@chr2:197274253..197274273
-
Hg19::chr2:197274274..197274279,-p@chr2:197274274..197274279
-
Hg19::chr2:77581116..77581120,-p@chr2:77581116..77581120
-
Hg19::chr2:77745761..77745773,-p1@CU676050
Hg19::chr2:77746703..77746711,-p9@LRRTM4
Hg19::chr2:77746775..77746779,-p14@LRRTM4
Hg19::chr2:77748814..77748822,-p@chr2:77748814..77748822
-
Hg19::chr2:77749342..77749350,-p7@LRRTM4
Hg19::chr3:111298881..111298895,-p@chr3:111298881..111298895
-
Hg19::chr3:158747347..158747353,+p@chr3:158747347..158747353
+
Hg19::chr3:168236611..168236612,-p@chr3:168236611..168236612
-
Hg19::chr3:168337915..168337930,-p@chr3:168337915..168337930
-
Hg19::chr3:178947187..178947192,+p@chr3:178947187..178947192
+
Hg19::chr3:189839512..189839520,-p21@LEPREL1
Hg19::chr3:189840223..189840229,-p26@LEPREL1
Hg19::chr3:6210160..6210166,+p@chr3:6210160..6210166
+
Hg19::chr3:6686484..6686491,+p@chr3:6686484..6686491
+
Hg19::chr3:6759235..6759249,+p@chr3:6759235..6759249
+
Hg19::chr3:77121235..77121260,+p@chr3:77121235..77121260
+
Hg19::chr3:78809269..78809276,+p@chr3:78809269..78809276
+
Hg19::chr3:79363599..79363606,+p@chr3:79363599..79363606
+
Hg19::chr3:83280278..83280318,+p@chr3:83280278..83280318
+
Hg19::chr4:185275104..185275133,-p3@LOC728175
Hg19::chr4:3881462..3881469,-p@chr4:3881462..3881469
-
Hg19::chr5:114289920..114289928,+p@chr5:114289920..114289928
+
Hg19::chr5:114291872..114291873,+p@chr5:114291872..114291873
+
Hg19::chr5:156349518..156349526,-p@chr5:156349518..156349526
-
Hg19::chr5:156349549..156349558,-p@chr5:156349549..156349558
-
Hg19::chr5:157836687..157836702,-p2@BC047601
Hg19::chr5:54320526..54320558,+p@chr5:54320526..54320558
+
Hg19::chr5:88646759..88646764,+p@chr5:88646759..88646764
+
Hg19::chr6:130878898..130878925,+p@chr6:130878898..130878925
+
Hg19::chr6:130881420..130881455,-p@chr6:130881420..130881455
-
Hg19::chr6:164466325..164466331,+p@chr6:164466325..164466331
+
Hg19::chr6:164466345..164466352,+p@chr6:164466345..164466352
+
Hg19::chr6:164466441..164466449,+p@chr6:164466441..164466449
+
Hg19::chr6:166581221..166581226,-p8@T
Hg19::chr6:166581265..166581274,-p5@T
Hg19::chr6:166581392..166581398,+p@chr6:166581392..166581398
+
Hg19::chr6:166581393..166581398,-p6@T
Hg19::chr6:166581486..166581494,+p@chr6:166581486..166581494
+
Hg19::chr6:166581583..166581586,+p@chr6:166581583..166581586
+
Hg19::chr6:166581590..166581596,+p@chr6:166581590..166581596
+
Hg19::chr6:166581606..166581615,+p@chr6:166581606..166581615
+
Hg19::chr6:166620455..166620466,+p@chr6:166620455..166620466
+
Hg19::chr6:24780070..24780082,+p@chr6:24780070..24780082
+
Hg19::chr6:41303336..41303361,+p1@NCR2
Hg19::chr6:41303372..41303386,+p2@NCR2
Hg19::chr7:86415255..86415288,+p@chr7:86415255..86415288
+
Hg19::chr8:128270027..128270033,-p@chr8:128270027..128270033
-
Hg19::chr8:84605743..84605748,-p@chr8:84605743..84605748
-
Hg19::chrX:11750805..11750811,+p@chrX:11750805..11750811
+
Hg19::chrX:11786438..11786451,+p9@MSL3
Hg19::chrX:11786454..11786465,+p25@MSL3
Hg19::chrX:11786498..11786511,+p10@MSL3
Hg19::chrX:18701132..18701138,-p@chrX:18701132..18701138
-
Hg19::chrX:78887125..78887131,+p@chrX:78887125..78887131
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:00515383 iron, 4 sulfur cluster binding0.0167858278404302
GO:0008177succinate dehydrogenase (ubiquinone) activity0.0167858278404302
GO:0016635oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor0.0167858278404302
GO:0019797procollagen-proline 3-dioxygenase activity0.0167858278404302
GO:0031544peptidyl-proline 3-dioxygenase activity0.0167858278404302
GO:0030903notochord development0.0167858278404302
GO:0019798procollagen-proline dioxygenase activity0.0167858278404302
GO:0008595determination of anterior/posterior axis, embryo0.0167858278404302
GO:0031543peptidyl-proline dioxygenase activity0.0167858278404302
GO:0007350blastoderm segmentation0.0167858278404302
GO:0000578embryonic axis specification0.0167858278404302
GO:0007351tripartite regional subdivision0.0167858278404302
GO:0009948anterior/posterior axis specification0.0215643152712485
GO:0001843neural tube closure0.0215643152712485
GO:0014020primary neural tube formation0.0215643152712485
GO:00515372 iron, 2 sulfur cluster binding0.0215643152712485
GO:0001839neural plate morphogenesis0.0215643152712485
GO:0001841neural tube formation0.0215643152712485
GO:0001840neural plate development0.0215643152712485
GO:0001838embryonic epithelial tube formation0.0215643152712485
GO:0005506iron ion binding0.0215643152712485
GO:0009798axis specification0.0215643152712485
GO:0001756somitogenesis0.0215643152712485
GO:0001570vasculogenesis0.0215643152712485
GO:0021915neural tube development0.0218502314848091
GO:0048568embryonic organ development0.0221139915192385
GO:0031418L-ascorbic acid binding0.0225845386272072
GO:0016331morphogenesis of embryonic epithelium0.0225845386272072
GO:0035282segmentation0.026751771639665
GO:0009880embryonic pattern specification0.0268158520672449
GO:0006099tricarboxylic acid cycle0.0347950444107773
GO:00515394 iron, 4 sulfur cluster binding0.0347950444107773
GO:0046356acetyl-CoA catabolic process0.0347950444107773
GO:0006084acetyl-CoA metabolic process0.0348997532553667
GO:0016706oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0.0348997532553667
GO:0007498mesoderm development0.0348997532553667
GO:0009109coenzyme catabolic process0.0348997532553667
GO:0051187cofactor catabolic process0.0375081296696971
GO:0009060aerobic respiration0.0375081296696971
GO:0009952anterior/posterior pattern formation0.039427089884365
GO:0045333cellular respiration0.0405546168028565
GO:0002009morphogenesis of an epithelium0.0429860620968055
GO:0006968cellular defense response0.047952679626127
GO:0051213dioxygenase activity0.0497766190448711
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen0.0497766190448711
GO:0016701oxidoreductase activity, acting on single donors with incorporation of molecular oxygen0.0497766190448711



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
adult organism1.26e-17115
neural tube3.24e-1457
neural rod3.24e-1457
future spinal cord3.24e-1457
neural keel3.24e-1457
central nervous system5.17e-1282
regional part of nervous system8.41e-1294
nervous system8.41e-1294
regional part of forebrain1.88e-1141
forebrain1.88e-1141
future forebrain1.88e-1141
anterior neural tube1.11e-1042
gray matter1.98e-1034
brain grey matter1.98e-1034
telencephalon3.13e-1034
regional part of brain3.18e-1059
regional part of telencephalon6.68e-1033
brain1.17e-0969
future brain1.17e-0969
cerebral hemisphere3.53e-0932
neurectoderm7.12e-0890
regional part of cerebral cortex9.68e-0822
neural plate2.07e-0786
presumptive neural plate2.07e-0786
larynx2.24e-079
neocortex5.31e-0720
Disease
Ontology termp-valuen
hematologic cancer1.51e-0951
immune system cancer1.51e-0951


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


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