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Coexpression cluster:C1559

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Full id: C1559_large_amygdala_pineal_temporal_medial_olfactory_cerebellum



Phase1 CAGE Peaks

  Short description
Hg19::chr10:105253535..105253604,+ p5@NEURL
Hg19::chr10:105253611..105253627,+ p10@NEURL
Hg19::chr10:105253790..105253822,+ p19@NEURL
Hg19::chr10:105254031..105254098,+ p2@NEURL
Hg19::chr10:105254104..105254135,+ p6@NEURL


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


uberon_data
disease_data


Uber Anatomy
Ontology termp-valuen
neural tube5.69e-5456
neural rod5.69e-5456
future spinal cord5.69e-5456
neural keel5.69e-5456
regional part of nervous system4.85e-5153
regional part of brain4.85e-5153
regional part of forebrain3.64e-4541
forebrain3.64e-4541
anterior neural tube3.64e-4541
future forebrain3.64e-4541
central nervous system4.76e-4581
brain2.82e-4368
future brain2.82e-4368
nervous system1.65e-4189
cerebral hemisphere2.19e-3732
telencephalon7.63e-3734
brain grey matter1.01e-3634
gray matter1.01e-3634
adult organism1.93e-35114
regional part of telencephalon1.57e-3432
neural plate7.83e-3382
presumptive neural plate7.83e-3382
regional part of cerebral cortex8.63e-3322
neurectoderm1.68e-3086
neocortex3.67e-3020
cerebral cortex5.49e-2825
pallium5.49e-2825
pre-chordal neural plate1.60e-2761
ecto-epithelium9.66e-25104
structure with developmental contribution from neural crest2.96e-20132
organ system subdivision4.09e-20223
ectoderm-derived structure3.86e-19171
ectoderm3.86e-19171
presumptive ectoderm3.86e-19171
tube5.59e-13192
organ part6.10e-12218
anatomical conduit2.44e-11240
temporal lobe3.70e-116
basal ganglion9.86e-119
nuclear complex of neuraxis9.86e-119
aggregate regional part of brain9.86e-119
collection of basal ganglia9.86e-119
cerebral subcortex9.86e-119
posterior neural tube3.14e-1015
chordal neural plate3.14e-1015
neural nucleus4.40e-109
nucleus of brain4.40e-109
gyrus7.52e-106
anatomical cluster8.64e-10373
organ1.07e-09503
diencephalon1.31e-097
future diencephalon1.31e-097
limbic system1.60e-085
occipital lobe1.73e-085
embryo2.91e-08592
parietal lobe3.60e-085
telencephalic nucleus5.62e-087
multi-tissue structure9.03e-08342
segmental subdivision of hindbrain1.17e-0712
hindbrain1.17e-0712
presumptive hindbrain1.17e-0712
brainstem1.40e-076
epithelium2.07e-07306
corpus striatum2.37e-074
striatum2.37e-074
ventral part of telencephalon2.37e-074
future corpus striatum2.37e-074
cell layer3.66e-07309
segmental subdivision of nervous system6.48e-0713
multi-cellular organism7.22e-07656
Disease
Ontology termp-valuen
squamous cell carcinoma6.02e-0714


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.19.12042
MA0004.10.626788
MA0006.12.00428
MA0007.11.47524
MA0009.11.11255
MA0014.12.48957
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.12.41212
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.10.603517
MA0056.10
MA0057.10.189508
MA0058.10.523638
MA0059.10.522232
MA0060.10.321781
MA0061.11.44118
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.10.247962
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.12.92967
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.14.10406
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.10.588959
MA0093.10.456342
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.10.459973
MA0103.10.442769
MA0105.13.82415
MA0106.10.779931
MA0107.10.378225
MA0108.20.94238
MA0109.10
MA0111.10.5713
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.11.76306
MA0117.11.1512
MA0119.10.504689
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.277033
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.12.01656
MA0146.10.6031
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.21.50246
MA0138.20.837782
MA0002.20.30855
MA0137.20.47779
MA0104.20.320919
MA0047.20.767096
MA0112.20.839774
MA0065.20.146576
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.98952
MA0155.10.813062
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.17.37801
MA0163.11.49262
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.27.74761
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.