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|gostat_on_coexpression_clusters=GO:0016291!acyl-CoA thioesterase activity!0.0164969859543486!26027$GO:0016289!CoA hydrolase activity!0.0164969859543486!26027$GO:0009266!response to temperature stimulus!0.0164969859543486!26027$GO:0009628!response to abiotic stimulus!0.0464543083416553!26027$GO:0016790!thiolester hydrolase activity!0.0464543083416553!26027$GO:0004091!carboxylesterase activity!0.0464543083416553!26027$GO:0006631!fatty acid metabolic process!0.0464543083416553!26027
|gostat_on_coexpression_clusters=GO:0016291!acyl-CoA thioesterase activity!0.0164969859543486!26027$GO:0016289!CoA hydrolase activity!0.0164969859543486!26027$GO:0009266!response to temperature stimulus!0.0164969859543486!26027$GO:0009628!response to abiotic stimulus!0.0464543083416553!26027$GO:0016790!thiolester hydrolase activity!0.0464543083416553!26027$GO:0004091!carboxylesterase activity!0.0464543083416553!26027$GO:0006631!fatty acid metabolic process!0.0464543083416553!26027
|id=C2593
|id=C2593
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!4.19e-47!115;UBERON:0005743!5.19e-37!86;UBERON:0000073!8.52e-36!94;UBERON:0001016!8.52e-36!94;UBERON:0001017!2.85e-34!82;UBERON:0001049!1.79e-32!57;UBERON:0005068!1.79e-32!57;UBERON:0006241!1.79e-32!57;UBERON:0007135!1.79e-32!57;UBERON:0000955!5.89e-31!69;UBERON:0006238!5.89e-31!69;UBERON:0002616!2.07e-30!59;UBERON:0003075!1.44e-29!86;UBERON:0007284!1.44e-29!86;UBERON:0002346!7.29e-29!90;UBERON:0002780!1.59e-26!41;UBERON:0001890!1.59e-26!41;UBERON:0006240!1.59e-26!41;UBERON:0000153!1.12e-25!129;UBERON:0007811!1.12e-25!129;UBERON:0003080!2.50e-25!42;UBERON:0000033!3.66e-25!123;UBERON:0004121!7.45e-23!169;UBERON:0000924!9.58e-23!173;UBERON:0006601!9.58e-23!173;UBERON:0003056!1.31e-22!61;UBERON:0001893!5.74e-22!34;UBERON:0002020!9.01e-22!34;UBERON:0003528!9.01e-22!34;UBERON:0002791!2.88e-21!33;UBERON:0001869!5.14e-21!32;UBERON:0000481!5.70e-18!347;UBERON:0000956!2.51e-16!25;UBERON:0000203!2.51e-16!25;UBERON:0002619!2.04e-15!22;UBERON:0000062!2.50e-14!511;UBERON:0001950!3.74e-14!20;UBERON:0000475!9.67e-14!365;UBERON:0000922!1.83e-13!612;UBERON:0000468!2.30e-12!659;UBERON:0002050!2.62e-12!605;UBERON:0005423!2.62e-12!605;UBERON:0000923!5.48e-12!604;UBERON:0005291!5.48e-12!604;UBERON:0006598!5.48e-12!604;UBERON:0002532!5.48e-12!604;UBERON:0000477!1.76e-10!286;UBERON:0000467!1.77e-10!625;UBERON:0000025!2.05e-10!194;UBERON:0000480!2.61e-10!626;UBERON:0000119!3.01e-10!312;UBERON:0004111!3.01e-10!241;UBERON:0000483!4.43e-10!309;UBERON:0003076!2.88e-08!15;UBERON:0003057!2.88e-08!15;UBERON:0000064!2.96e-07!219;UBERON:0002420!3.35e-07!9;UBERON:0007245!3.35e-07!9;UBERON:0010009!3.35e-07!9;UBERON:0010011!3.35e-07!9;UBERON:0000454!3.35e-07!9;UBERON:0004732!4.45e-07!13;UBERON:0002308!6.73e-07!9;UBERON:0000125!6.73e-07!9;UBERON:0000479!7.68e-07!787
}}
}}

Revision as of 14:26, 21 May 2012


Full id: C2593_heart_thyroid_retina_left_umbilical_smooth_pituitary



Phase1 CAGE Peaks

Hg19::chr1:55013889..55013912,+p1@ACOT11
Hg19::chr1:55013918..55013934,+p3@ACOT11
Hg19::chr4:186733169..186733170,-p29@SORBS2
Hg19::chr4:186733332..186733356,-p5@SORBS2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0016291acyl-CoA thioesterase activity0.0164969859543486
GO:0016289CoA hydrolase activity0.0164969859543486
GO:0009266response to temperature stimulus0.0164969859543486
GO:0009628response to abiotic stimulus0.0464543083416553
GO:0016790thiolester hydrolase activity0.0464543083416553
GO:0004091carboxylesterase activity0.0464543083416553
GO:0006631fatty acid metabolic process0.0464543083416553



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism4.19e-47115
regional part of nervous system8.52e-3694
nervous system8.52e-3694
central nervous system2.85e-3482
neural tube1.79e-3257
neural rod1.79e-3257
future spinal cord1.79e-3257
neural keel1.79e-3257
brain5.89e-3169
future brain5.89e-3169
regional part of brain2.07e-3059
neural plate1.44e-2986
presumptive neural plate1.44e-2986
neurectoderm7.29e-2990
regional part of forebrain1.59e-2641
forebrain1.59e-2641
future forebrain1.59e-2641
anterior region of body1.12e-25129
craniocervical region1.12e-25129
anterior neural tube2.50e-2542
head3.66e-25123
ectoderm-derived structure7.45e-23169
ectoderm9.58e-23173
presumptive ectoderm9.58e-23173
pre-chordal neural plate1.31e-2261
telencephalon5.74e-2234
gray matter9.01e-2234
brain grey matter9.01e-2234
regional part of telencephalon2.88e-2133
cerebral hemisphere5.14e-2132
multi-tissue structure5.70e-18347
cerebral cortex2.51e-1625
pallium2.51e-1625
regional part of cerebral cortex2.04e-1522
organ2.50e-14511
neocortex3.74e-1420
organism subdivision9.67e-14365
embryo1.83e-13612
multi-cellular organism2.30e-12659
embryonic structure2.62e-12605
developing anatomical structure2.62e-12605
germ layer5.48e-12604
embryonic tissue5.48e-12604
presumptive structure5.48e-12604
epiblast (generic)5.48e-12604
anatomical cluster1.76e-10286
anatomical system1.77e-10625
tube2.05e-10194
anatomical group2.61e-10626
cell layer3.01e-10312
anatomical conduit3.01e-10241
epithelium4.43e-10309
posterior neural tube2.88e-0815
chordal neural plate2.88e-0815
organ part2.96e-07219
basal ganglion3.35e-079
nuclear complex of neuraxis3.35e-079
aggregate regional part of brain3.35e-079
collection of basal ganglia3.35e-079
cerebral subcortex3.35e-079
segmental subdivision of nervous system4.45e-0713
nucleus of brain6.73e-079
neural nucleus6.73e-079
tissue7.68e-07787


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.