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|gostat_on_coexpression_clusters=GO:0019198!transmembrane receptor protein phosphatase activity!0.0250990844682031!5800$GO:0005001!transmembrane receptor protein tyrosine phosphatase activity!0.0250990844682031!5800$GO:0005887!integral to plasma membrane!0.0250990844682031!5800;2066$GO:0031226!intrinsic to plasma membrane!0.0250990844682031!5800;2066$GO:0006793!phosphorus metabolic process!0.0266015515049223!5800;2066$GO:0006796!phosphate metabolic process!0.0266015515049223!5800;2066$GO:0004888!transmembrane receptor activity!0.0321580955874543!5800;2066$GO:0043687!post-translational protein modification!0.0321580955874543!5800;2066$GO:0044459!plasma membrane part!0.0321580955874543!5800;2066$GO:0046982!protein heterodimerization activity!0.033791670924434!2066$GO:0006464!protein modification process!0.033791670924434!5800;2066$GO:0004714!transmembrane receptor protein tyrosine kinase activity!0.033791670924434!2066$GO:0043412!biopolymer modification!0.033791670924434!5800;2066$GO:0019199!transmembrane receptor protein kinase activity!0.0341160217542822!2066$GO:0004872!receptor activity!0.0352430259229253!5800;2066$GO:0060089!molecular transducer activity!0.0409379450656799!5800;2066$GO:0004871!signal transducer activity!0.0409379450656799!5800;2066$GO:0007169!transmembrane receptor protein tyrosine kinase signaling pathway!0.0409379450656799!2066$GO:0005886!plasma membrane!0.0409379450656799!5800;2066$GO:0004725!protein tyrosine phosphatase activity!0.0409379450656799!5800$GO:0006470!protein amino acid dephosphorylation!0.044156149366298!5800$GO:0016311!dephosphorylation!0.0469563405358217!5800$GO:0007167!enzyme linked receptor protein signaling pathway!0.0469563405358217!2066$GO:0004713!protein-tyrosine kinase activity!0.0469563405358217!2066$GO:0004721!phosphoprotein phosphatase activity!0.0469563405358217!5800
|gostat_on_coexpression_clusters=GO:0019198!transmembrane receptor protein phosphatase activity!0.0250990844682031!5800$GO:0005001!transmembrane receptor protein tyrosine phosphatase activity!0.0250990844682031!5800$GO:0005887!integral to plasma membrane!0.0250990844682031!5800;2066$GO:0031226!intrinsic to plasma membrane!0.0250990844682031!5800;2066$GO:0006793!phosphorus metabolic process!0.0266015515049223!5800;2066$GO:0006796!phosphate metabolic process!0.0266015515049223!5800;2066$GO:0004888!transmembrane receptor activity!0.0321580955874543!5800;2066$GO:0043687!post-translational protein modification!0.0321580955874543!5800;2066$GO:0044459!plasma membrane part!0.0321580955874543!5800;2066$GO:0046982!protein heterodimerization activity!0.033791670924434!2066$GO:0006464!protein modification process!0.033791670924434!5800;2066$GO:0004714!transmembrane receptor protein tyrosine kinase activity!0.033791670924434!2066$GO:0043412!biopolymer modification!0.033791670924434!5800;2066$GO:0019199!transmembrane receptor protein kinase activity!0.0341160217542822!2066$GO:0004872!receptor activity!0.0352430259229253!5800;2066$GO:0060089!molecular transducer activity!0.0409379450656799!5800;2066$GO:0004871!signal transducer activity!0.0409379450656799!5800;2066$GO:0007169!transmembrane receptor protein tyrosine kinase signaling pathway!0.0409379450656799!2066$GO:0005886!plasma membrane!0.0409379450656799!5800;2066$GO:0004725!protein tyrosine phosphatase activity!0.0409379450656799!5800$GO:0006470!protein amino acid dephosphorylation!0.044156149366298!5800$GO:0016311!dephosphorylation!0.0469563405358217!5800$GO:0007167!enzyme linked receptor protein signaling pathway!0.0469563405358217!2066$GO:0004713!protein-tyrosine kinase activity!0.0469563405358217!2066$GO:0004721!phosphoprotein phosphatase activity!0.0469563405358217!5800
|id=C1665
|id=C1665
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000073!3.08e-43!94;UBERON:0001016!3.08e-43!94;UBERON:0005743!3.41e-41!86;UBERON:0001017!9.56e-41!82;UBERON:0001049!2.22e-39!57;UBERON:0005068!2.22e-39!57;UBERON:0006241!2.22e-39!57;UBERON:0007135!2.22e-39!57;UBERON:0007023!3.89e-34!115;UBERON:0002616!3.79e-33!59;UBERON:0002346!6.66e-33!90;UBERON:0003080!8.96e-33!42;UBERON:0002780!2.77e-32!41;UBERON:0001890!2.77e-32!41;UBERON:0006240!2.77e-32!41;UBERON:0000955!6.52e-32!69;UBERON:0006238!6.52e-32!69;UBERON:0003075!8.14e-32!86;UBERON:0007284!8.14e-32!86;UBERON:0000924!8.45e-30!173;UBERON:0006601!8.45e-30!173;UBERON:0004121!1.26e-28!169;UBERON:0001893!1.84e-27!34;UBERON:0002020!2.08e-27!34;UBERON:0003528!2.08e-27!34;UBERON:0002791!1.48e-26!33;UBERON:0001869!5.24e-26!32;UBERON:0003056!1.65e-25!61;UBERON:0000153!1.70e-24!129;UBERON:0007811!1.70e-24!129;UBERON:0000033!3.93e-24!123;UBERON:0000956!6.22e-20!25;UBERON:0000203!6.22e-20!25;UBERON:0002619!1.11e-19!22;UBERON:0001950!6.72e-18!20;UBERON:0000477!2.86e-15!286;UBERON:0000064!1.16e-12!219;UBERON:0004111!2.06e-12!241;UBERON:0000481!4.43e-12!347;UBERON:0000475!6.02e-12!365;UBERON:0000025!8.29e-12!194;UBERON:0000922!4.74e-11!612;UBERON:0000468!1.48e-10!659;UBERON:0000483!1.47e-09!309;UBERON:0002420!3.03e-09!9;UBERON:0007245!3.03e-09!9;UBERON:0010009!3.03e-09!9;UBERON:0010011!3.03e-09!9;UBERON:0000454!3.03e-09!9;UBERON:0000119!3.80e-09!312;UBERON:0002050!5.71e-09!605;UBERON:0005423!5.71e-09!605;UBERON:0002308!6.44e-09!9;UBERON:0000125!6.44e-09!9;UBERON:0000923!1.13e-08!604;UBERON:0005291!1.13e-08!604;UBERON:0006598!1.13e-08!604;UBERON:0002532!1.13e-08!604;UBERON:0003076!5.53e-08!15;UBERON:0003057!5.53e-08!15;UBERON:0000467!8.82e-08!625;UBERON:0000480!1.12e-07!626;UBERON:0009663!2.23e-07!7;UBERON:0002298!3.96e-07!8;UBERON:0000062!4.54e-07!511;UBERON:0000200!8.61e-07!6
}}
}}

Revision as of 14:14, 21 May 2012


Full id: C1665_kidney_occipital_duodenum_temporal_parietal_Neural_brain



Phase1 CAGE Peaks

Hg19::chr12:15475214..15475223,+p9@PTPRO
Hg19::chr12:15475249..15475280,+p4@PTPRO
Hg19::chr12:15475292..15475303,+p7@PTPRO
Hg19::chr12:15475462..15475483,+p5@PTPRO
Hg19::chr2:213403858..213403879,-p2@ERBB4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0019198transmembrane receptor protein phosphatase activity0.0250990844682031
GO:0005001transmembrane receptor protein tyrosine phosphatase activity0.0250990844682031
GO:0005887integral to plasma membrane0.0250990844682031
GO:0031226intrinsic to plasma membrane0.0250990844682031
GO:0006793phosphorus metabolic process0.0266015515049223
GO:0006796phosphate metabolic process0.0266015515049223
GO:0004888transmembrane receptor activity0.0321580955874543
GO:0043687post-translational protein modification0.0321580955874543
GO:0044459plasma membrane part0.0321580955874543
GO:0046982protein heterodimerization activity0.033791670924434
GO:0006464protein modification process0.033791670924434
GO:0004714transmembrane receptor protein tyrosine kinase activity0.033791670924434
GO:0043412biopolymer modification0.033791670924434
GO:0019199transmembrane receptor protein kinase activity0.0341160217542822
GO:0004872receptor activity0.0352430259229253
GO:0060089molecular transducer activity0.0409379450656799
GO:0004871signal transducer activity0.0409379450656799
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway0.0409379450656799
GO:0005886plasma membrane0.0409379450656799
GO:0004725protein tyrosine phosphatase activity0.0409379450656799
GO:0006470protein amino acid dephosphorylation0.044156149366298
GO:0016311dephosphorylation0.0469563405358217
GO:0007167enzyme linked receptor protein signaling pathway0.0469563405358217
GO:0004713protein-tyrosine kinase activity0.0469563405358217
GO:0004721phosphoprotein phosphatase activity0.0469563405358217



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of nervous system3.08e-4394
nervous system3.08e-4394
central nervous system9.56e-4182
neural tube2.22e-3957
neural rod2.22e-3957
future spinal cord2.22e-3957
neural keel2.22e-3957
adult organism3.89e-34115
regional part of brain3.79e-3359
neurectoderm6.66e-3390
anterior neural tube8.96e-3342
regional part of forebrain2.77e-3241
forebrain2.77e-3241
future forebrain2.77e-3241
brain6.52e-3269
future brain6.52e-3269
neural plate8.14e-3286
presumptive neural plate8.14e-3286
ectoderm8.45e-30173
presumptive ectoderm8.45e-30173
ectoderm-derived structure1.26e-28169
telencephalon1.84e-2734
gray matter2.08e-2734
brain grey matter2.08e-2734
regional part of telencephalon1.48e-2633
cerebral hemisphere5.24e-2632
pre-chordal neural plate1.65e-2561
anterior region of body1.70e-24129
craniocervical region1.70e-24129
head3.93e-24123
cerebral cortex6.22e-2025
pallium6.22e-2025
regional part of cerebral cortex1.11e-1922
neocortex6.72e-1820
anatomical cluster2.86e-15286
organ part1.16e-12219
anatomical conduit2.06e-12241
multi-tissue structure4.43e-12347
organism subdivision6.02e-12365
tube8.29e-12194
embryo4.74e-11612
multi-cellular organism1.48e-10659
epithelium1.47e-09309
basal ganglion3.03e-099
nuclear complex of neuraxis3.03e-099
aggregate regional part of brain3.03e-099
collection of basal ganglia3.03e-099
cerebral subcortex3.03e-099
cell layer3.80e-09312
embryonic structure5.71e-09605
developing anatomical structure5.71e-09605
nucleus of brain6.44e-099
neural nucleus6.44e-099
germ layer1.13e-08604
embryonic tissue1.13e-08604
presumptive structure1.13e-08604
epiblast (generic)1.13e-08604
posterior neural tube5.53e-0815
chordal neural plate5.53e-0815
anatomical system8.82e-08625
anatomical group1.12e-07626
telencephalic nucleus2.23e-077
brainstem3.96e-078
organ4.54e-07511
gyrus8.61e-076


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.