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Coexpression cluster:C2264

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Full id: C2264_occipital_parietal_pineal_temporal_duodenum_brain_optic



Phase1 CAGE Peaks

Hg19::chr13:44361004..44361022,-p3@ENOX1
Hg19::chr13:44361025..44361052,-p1@ENOX1
Hg19::chr13:44361058..44361095,-p2@ENOX1
Hg19::chr13:44361100..44361121,-p4@ENOX1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.22e-2657
neural rod1.22e-2657
future spinal cord1.22e-2657
neural keel1.22e-2657
regional part of nervous system1.14e-2594
nervous system1.14e-2594
central nervous system4.55e-2582
regional part of brain3.17e-2359
brain4.50e-2369
future brain4.50e-2369
ectoderm-derived structure2.07e-22169
neural plate2.16e-2286
presumptive neural plate2.16e-2286
regional part of forebrain3.96e-2241
forebrain3.96e-2241
future forebrain3.96e-2241
anterior neural tube4.00e-2242
ectoderm5.85e-21173
presumptive ectoderm5.85e-21173
organism subdivision6.34e-21365
adult organism8.59e-21115
neurectoderm3.61e-2090
multi-tissue structure1.13e-19347
cell layer2.05e-19312
epithelium4.05e-19309
telencephalon5.83e-1934
gray matter7.12e-1934
brain grey matter7.12e-1934
regional part of telencephalon2.55e-1833
head3.43e-18123
anterior region of body1.04e-17129
craniocervical region1.04e-17129
cerebral hemisphere1.08e-1732
pre-chordal neural plate9.63e-1761
anatomical cluster3.36e-15286
tube3.91e-15194
regional part of cerebral cortex2.56e-1422
multi-cellular organism4.58e-14659
cerebral cortex1.82e-1325
pallium1.82e-1325
anatomical system2.57e-13625
neocortex3.04e-1320
anatomical group4.84e-13626
anatomical conduit6.94e-13241
embryo3.91e-12612
embryonic structure4.87e-12605
developing anatomical structure4.87e-12605
germ layer1.09e-11604
embryonic tissue1.09e-11604
presumptive structure1.09e-11604
epiblast (generic)1.09e-11604
somite2.56e-1183
paraxial mesoderm2.56e-1183
presomitic mesoderm2.56e-1183
presumptive segmental plate2.56e-1183
trunk paraxial mesoderm2.56e-1183
presumptive paraxial mesoderm2.56e-1183
organ part4.39e-10219
dermomyotome9.00e-1070
muscle tissue1.54e-0963
musculature1.54e-0963
musculature of body1.54e-0963
skeletal muscle tissue3.56e-0961
striated muscle tissue3.56e-0961
myotome3.56e-0961
organ2.06e-08511
tissue4.33e-08787
multilaminar epithelium8.28e-0882
nucleus of brain6.08e-079
neural nucleus6.08e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.