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Coexpression cluster:C4851

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Full id: C4851_Osteoblast_occipital_skeletal_Adipocyte_Mesenchymal_leiomyoma_Smooth



Phase1 CAGE Peaks

Hg19::chrX:134166948..134166995,+p4@FAM127A
Hg19::chrX:134167069..134167118,+p3@FAM127A
Hg19::chrX:134167308..134167338,+p@chrX:134167308..134167338
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
organism subdivision9.91e-22365
multi-cellular organism3.18e-21659
cell layer2.71e-18312
epithelium3.35e-18309
anatomical cluster1.81e-17286
anatomical conduit2.25e-16241
anatomical system4.55e-15625
multi-tissue structure6.01e-15347
anatomical group1.07e-14626
somite3.44e-1483
paraxial mesoderm3.44e-1483
presomitic mesoderm3.44e-1483
presumptive segmental plate3.44e-1483
trunk paraxial mesoderm3.44e-1483
presumptive paraxial mesoderm3.44e-1483
trunk mesenchyme3.48e-14143
multilaminar epithelium7.13e-1482
embryo1.06e-13612
dermomyotome2.39e-1370
tube3.35e-13194
muscle tissue1.13e-1263
musculature1.13e-1263
musculature of body1.13e-1263
skeletal muscle tissue1.41e-1261
striated muscle tissue1.41e-1261
myotome1.41e-1261
embryonic structure2.47e-12605
developing anatomical structure2.47e-12605
germ layer2.81e-12604
embryonic tissue2.81e-12604
presumptive structure2.81e-12604
epiblast (generic)2.81e-12604
trunk6.47e-12216
splanchnic layer of lateral plate mesoderm1.55e-1184
vasculature4.09e-1079
vascular system4.09e-1079
blood vessel1.48e-0960
epithelial tube open at both ends1.48e-0960
blood vasculature1.48e-0960
vascular cord1.48e-0960
epithelial tube3.50e-09118
artery4.47e-0942
arterial blood vessel4.47e-0942
arterial system4.47e-0942
vessel4.69e-0969
central nervous system5.02e-0982
adult organism3.02e-08115
organ part4.72e-08219
unilaminar epithelium4.87e-08138
neural tube1.47e-0757
neural rod1.47e-0757
future spinal cord1.47e-0757
neural keel1.47e-0757
ectoderm-derived structure1.47e-07169
regional part of brain2.60e-0759
systemic artery2.94e-0733
systemic arterial system2.94e-0733
regional part of nervous system3.39e-0794
nervous system3.39e-0794
ectoderm3.80e-07173
presumptive ectoderm3.80e-07173
circulatory system5.89e-07113


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.