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Coexpression cluster:C3696

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Full id: C3696_cerebellum_occipital_carcinoid_neuroectodermal_parietal_neuroepithelioma_medial



Phase1 CAGE Peaks

Hg19::chr17:7833111..7833187,-p1@KCNAB3
Hg19::chr7:122004464..122004468,-p@chr7:122004464..122004468
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Hg19::chr7:122526529..122526589,-p2@CADPS2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
ectoderm-derived structure1.68e-33171
ectoderm1.68e-33171
presumptive ectoderm1.68e-33171
central nervous system5.89e-3281
nervous system1.76e-3189
neurectoderm3.03e-2986
neural tube3.72e-2856
neural rod3.72e-2856
future spinal cord3.72e-2856
neural keel3.72e-2856
neural plate1.20e-2682
presumptive neural plate1.20e-2682
regional part of nervous system1.69e-2653
regional part of brain1.69e-2653
brain3.82e-2668
future brain3.82e-2668
anatomical cluster6.86e-25373
adult organism1.10e-24114
organ system subdivision1.97e-22223
structure with developmental contribution from neural crest3.98e-22132
ecto-epithelium8.39e-21104
regional part of forebrain1.40e-2041
forebrain1.40e-2041
anterior neural tube1.40e-2041
future forebrain1.40e-2041
multi-tissue structure5.20e-19342
anatomical conduit7.91e-19240
pre-chordal neural plate9.37e-1961
cerebral hemisphere1.21e-1832
telencephalon1.35e-1834
brain grey matter1.43e-1834
gray matter1.43e-1834
regional part of telencephalon1.95e-1732
cell layer3.60e-17309
epithelium1.01e-16306
cerebral cortex1.90e-1625
pallium1.90e-1625
regional part of cerebral cortex1.22e-1522
tube6.00e-15192
neocortex2.22e-1420
multi-cellular organism2.46e-14656
organ part1.12e-13218
embryo6.60e-13592
germ layer1.09e-11560
germ layer / neural crest1.09e-11560
embryonic tissue1.09e-11560
presumptive structure1.09e-11560
germ layer / neural crest derived structure1.09e-11560
epiblast (generic)1.09e-11560
developing anatomical structure2.73e-11581
embryonic structure2.75e-11564
anatomical group5.42e-09625
anatomical system8.17e-09624
posterior neural tube1.02e-0815
chordal neural plate1.02e-0815
segmental subdivision of hindbrain3.63e-0712
hindbrain3.63e-0712
presumptive hindbrain3.63e-0712


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.