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Coexpression cluster:C1289: Difference between revisions

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|tfbs_overrepresentation_for_novel_motifs=0.392069,0.0232809,0.384703,0.529489,0.343148,1.30874,0.604235,1.20202,0.224331,0.0544999,0.497563,0.647852,0.184039,0.592674,0.341795,0.365029,0.827563,0.28906,0.19568,0.0986842,0.384762,0.23059,0.520063,0.338096,0.430372,0.670692,0.164928,0.517892,0.346214,0.150685,0.475674,0.864517,0.257226,1.04347,0.309012,0.021349,0.305874,0.529001,1.4117,0.207499,0.829015,0.459366,0.0729319,0.340293,0.265117,0.415364,0.60533,0.486696,0.237549,0.346342,0.684981,0.617179,0.117127,0.941629,1.09491,0.595623,0.924875,0.562713,0.150585,0.561701,0.905643,0.60771,0.224801,0.799729,0.625758,0.76514,1.18348,1.55228,0.854088,1.38987,0.4462,0.232216,0.115253,1.0929,0.179863,0.168304,0.156354,0.782748,1.98123,0.424224,0.580264,0.798651,0.625403,0.229431,1.04131,0.0324537,0.097572,0.146388,0.711163,1.65172,1.27705,1.01423,0.881388,0.26423,0.343884,0.277058,0.194299,0.924148,0.715799,0.132387,0.28424,2.03227,0.918549,0.831244,0.753567,0.493026,0.815341,0.589207,0.43012,0.327379,0.395884,0.915771,0.379203,0.507004,1.22894,0.304323,0.039977,0.474472,0.762789,0.26701,1.0846,0.708722,0.525076,1.53817,1.33983,0.783512,0.597853,0.886402,1.12733,1.39367,1.01492,0.47854,1.14174,0.633392,1.28996,0.140417,0.469685,0.518459,1.24743,2.10682,1.70417,1.21002,0.59959,0.920609,0.755332,0.554217,1.74998,1.94751,0.456039,0.26104,0.106334,0.0685123,1.0153,0.216774,0.607223,1.42052,0.694887,0.329354,0.430431,0.401655,1.2088,0.996724,0.850033,0.404861,0.7715,0.624608,0.24928,0.602897,0.00626991
}}
}}

Revision as of 14:48, 26 November 2012


Full id: C1289_mesenchymal_Smooth_Cardiac_Mesothelial_Sertoli_leiomyoma_Preadipocyte



Phase1 CAGE Peaks

Hg19::chr9:6215137..6215161,+p@chr9:6215137..6215161
+
Hg19::chr9:6215799..6215815,+p1@IL33
Hg19::chr9:6256728..6256739,+p@chr9:6256728..6256739
+
Hg19::chr9:6256995..6256999,+p@chr9:6256995..6256999
+
Hg19::chr9:6257148..6257157,+p@chr9:6257148..6257157
+
Hg19::chr9:6257179..6257191,+p@chr9:6257179..6257191
+
Hg19::chr9:6257212..6257223,+p@chr9:6257212..6257223
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
splanchnic layer of lateral plate mesoderm1.34e-3183
heart9.02e-2224
primitive heart tube9.02e-2224
primary heart field9.02e-2224
anterior lateral plate mesoderm9.02e-2224
heart tube9.02e-2224
heart primordium9.02e-2224
cardiac mesoderm9.02e-2224
cardiogenic plate9.02e-2224
heart rudiment9.02e-2224
artery1.52e-2042
arterial blood vessel1.52e-2042
arterial system1.52e-2042
epithelial tube open at both ends3.28e-2059
blood vessel3.28e-2059
blood vasculature3.28e-2059
vascular cord3.28e-2059
muscle tissue5.95e-1964
musculature5.95e-1964
musculature of body5.95e-1964
systemic artery6.11e-1933
systemic arterial system6.11e-1933
primary circulatory organ1.53e-1827
skeletal muscle tissue1.74e-1862
striated muscle tissue1.74e-1862
myotome1.74e-1862
cardiovascular system3.85e-18109
epithelial tube2.66e-17117
circulatory system3.11e-17112
vessel5.42e-1668
paraxial mesoderm2.27e-1572
presumptive paraxial mesoderm2.27e-1572
dense mesenchyme tissue5.30e-1573
somite1.07e-1471
presomitic mesoderm1.07e-1471
presumptive segmental plate1.07e-1471
dermomyotome1.07e-1471
trunk paraxial mesoderm1.07e-1471
anatomical conduit1.57e-14240
vasculature2.34e-1478
vascular system2.34e-1478
anatomical cluster4.05e-14373
mesoderm1.03e-13315
mesoderm-derived structure1.03e-13315
presumptive mesoderm1.03e-13315
tube5.86e-13192
multilaminar epithelium8.57e-1383
reproductive structure9.46e-1359
reproductive system9.46e-1359
epithelial vesicle2.12e-1278
epithelium2.96e-12306
trunk mesenchyme3.95e-12122
multi-tissue structure5.93e-12342
cell layer6.63e-12309
smooth muscle tissue7.36e-1115
embryonic structure1.25e-10564
female gonad1.64e-1013
germ layer1.88e-10560
germ layer / neural crest1.88e-10560
embryonic tissue1.88e-10560
presumptive structure1.88e-10560
germ layer / neural crest derived structure1.88e-10560
epiblast (generic)1.88e-10560
unilaminar epithelium3.06e-10148
mesenchyme4.71e-10160
entire embryonic mesenchyme4.71e-10160
embryo7.78e-10592
developing anatomical structure1.07e-09581
compound organ1.13e-0868
right ovary1.15e-085
reproductive organ1.95e-0848
thoracic segment blood vessel3.20e-085
subclavian artery3.20e-085
gonad5.47e-0821
indifferent external genitalia5.47e-0821
indifferent gonad5.47e-0821
gonad primordium5.47e-0821
anatomical system7.49e-08624
blood vessel smooth muscle7.99e-0810
arterial system smooth muscle7.99e-0810
artery smooth muscle tissue7.99e-0810
aorta smooth muscle tissue7.99e-0810
anatomical group8.77e-08625
adult organism9.08e-08114
heart blood vessel9.49e-085

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.