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Coexpression cluster:C3211: Difference between revisions

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|tf_chipseq_enrich=ZNF263#10127;3:8.22184163701068:0.00179904392556587:0.0108978799688054
|tf_chipseq_enrich=ZNF263#10127;3:8.22184163701068:0.00179904392556587:0.0108978799688054
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7332,0.0145999,0.0656973,0.211746,0.220538,0.0801488,0.0757897,0.161801,0.193215,0.0549034,0.0779715,0.0561838,0.0417636,0.0345419,0.0388736,0.254674,0.170307,0.201033,0.0488949,0.174921,0.370421,0.0330727,0.348757,0.219556,0.0394698,0.0596469,0.419264,0.122476,0.108872,0.11002,0.26144,0.0286025,0.549354,0.144567,0.038848,0.0874516,0.0550279,0.144067,0.253693,0.217069,0.190048,0.131088,0.394069,0.237101,0.286988,0.0761239,0.172491,0.0818785,0.182701,0.335058,0.147698,0.141463,0.167267,0.140622,0.0889592,0.309588,0.28711,0.0473033,0.094881,0.445524,0.132886,0.0774373,0.109194,0.128564,0.131452,0.687347,0.448776,0.051838,0.0993999,0.0500365,0.061829,0.0755121,0.0936516,0.144075,0.0340203,0.0741807,0.277091,0.739716,0.655293,0.21727,0.289306,0.119215,0.192475,0.177967,0.0088427,0.057571,0.047591,0.0899568,0.0608699,0.175319,0.300597,0.0713214,0.223874,0.291114,0.0355833,0.125606,0.175094,0.911304,0.519327,0.206454,0.218192,0.108277,0.0673484,0.108748,0.0494066,0.0958493,0.205732,0.0755808,0.045654,0.110216,0.070276,0.226171,0.153469,0.0376916,0.13262,0.0450031,0.0539144,0.114242,0.0929549,0.172425,0.104948,0.221645,0.057168,0.234298,0.0759837,0.286863,0.152372,0.194941,0.218271,0.101607,0.060512,0.172982,0.340936,0.151597,0.0626744,0.191335,0.148574,0.504592,0.155821,0.0718905,0.0919008,0.0602373,0.144304,0.15063,0.0973823,0.15503,0.170295,0.193653,0.137219,0.228144,0.251466,0.288096,0.11903,0.0838874,0.331451,0.113145,0.112651,0.186638,0.174776,0.0948451,0.264079,0.249049,0.140533,0.0997756,0.0364628,0.103667,0.113069,0.025556,0.16791,0.09066,0.220462,0.166967,0.188651,0.0813902,0.184948,0.156261,0.311847,0.511859,0.0590944,0.247324,0.178389,0.218229,0.231073,0.0972686,0.619906,0.0360851,0.412187,0.131093,0.0434602,0.133616,0.418146,0.0115948,0.449036,0.407369,0.231447,0.544776,0.43956,0.37006,0.42622,0.448797,0.197484,0.396996,0.36145,0.0160226,0.381071,0.216033,0.0863135,0.432035,0.722159,0.390366,0.48809,0.50058,0.443185,0.522904,0.3468,0.871256,0.227104,0.518585,0.617852,0.38649,0.284625,0.0344717,0.55194,0.729153,0.28907,0.164197,0.462688,0.287881,0.574635,0.478174,0.336276,0.468444,0.0366482,0.446557,0.243383,0.777351,0.390974,0.73485,0.683217,0.161598,0.751174,0.644754,0.496032,0.799185,0.37357,0.78509,0.477353,0.452741,0.746954,0.771991,0.20342,0.200493,0.20558,0.300504,0.25656,0.425963,0.349197,0.383291,0.156104,0.141318,0.411941,0.0961477,0.314438,0.0720718,0.163828,0.230581,0.120226,0.0448825,0.562405,0.314429,0.181415,0.282286,0.446891,0.24884,0.408413,0.516511,0.322213,0.656109,0.33942,0.61031,0.0136291,0.522605,0.802166,0.180745,0.222037,0.416621,0.416292,0.462712,0.734551,0.579431,0.204817,0.452428,0.138871,0.673493,0.166905,0.19783,0.0833851,0.316453,0.48065,0.175199,0.332919,0.373557,0.523625,0.408861,0.365487,0.534741,0.39088,0.363192,0.236011,0.203486,0.273398,0.375787,0.4466,0.0704514,0.275347,0.019895,0.305885,0.241132,0.371414,0.30666,0.303709,0.495883,0.386538,0.508064,0.250964,0.383276,0.457886,0.504711,0.220231,0.509064,0.196976,0.191517,0.463751,0.601877,0.307334,0.459728,0.283463,0.201728,0.472935,0.0932845,0.273281,0.368095,0.275089,0.384593,0.47795,0.359231,0.339729,0.197805,0.0690807,0.387069,0.332774,0.52832,0.299887,0.0814305,0.205413,0.17639,0.0779009,0.276869,0.205298,0.0337138,0.18966,0.258854,0.188263,0.0719199,0.264884,0.162568,0.19104,0.000822975,0.219428,0.208013,0.0900729,0.0953646,0.166124,0.252184,0.378361,0.255516,0.20753,0.447185,0.179412,0.193601,0.220904,0.222977,0.341681,0.310674,0.21801,0.198614,0.186804,0.123324,0.199468,0.0325925,0.0933115,0.12405,0.179889,0.226869,0.27872,0.0855609,0.131118,0.20837,0.247588,0.222339,0.0673329,0.20847,0.266544,0.113092,0.145701,0.229428,0.162145,0.228955,0.168748,0.0384949,0.0660995,0.0521984,0.0455518,0.268741,0.201602,0.350452,0.154941,0.120196,0.0986735,0.108462,0.0595618,0.21593,0.158479,0.220319,0.195218,0.124213,0.259632,0.30793,0.180606,0.159884,0.257294,0.150733,0.217112,0.123917,0.184317,0.185335,0.0723291,0.258496,0.261744,0.203781,0.0246892,0.207559,0.141867,0.193031,0.249101,0.115972,0.224568,0.246105,0.173026,0.200432,0.139785,0.197112,0.240478,0.0129343,0.13108,0.256963,0.222798,0.000975743,0.176789,0.0969345,0.202137,0.310405,0.280943,0.218161,9.87797e-05,0.202065,0.106739,0.0536053,0.0537737,0.15113,0.078016,0.0407233,0.0537355,0.319922,0.261724,0.211332,0.187731,0.233626,0.189559,0.0812887,0.0981146,0.064145,0.121913,0.0638699,0.104603,0.0663259,0.0762523,0.128736,0.109171,0.04411,0.066952,0.089609,0.0367455,0.13497,0.204393,0.295769,0.286691,0.347036,0.141729,0.263159,0.255956,0.200105,0.227491,0.29837,0.253509,0.177664,0.28365,0.00384051,0.000422974,0.160658,0.206239,0.19924,0.28689,0.236464,0.325148,0.115817,0.218052,0.223831,0.11528,0.194982,0.190993,0.281727,0.283218,0.249955,0.164638,0.224257,0.0935776,0.327622,0.225752,0.207791,0.0958756,0.000113015,0.316866,0.171683,0.158847,0.271275,0.071111,0.270604,0.101021,0.222548,0.175934,0.157274,0.215705,0.252796,0.205954,0.361435
|tfbs_overrepresentation_for_novel_motifs=0.699513,0.14394,0.690871,0.855819,0.641468,0.853988,2.1595,0.494933,0.491742,0.63186,0.820209,0.985163,2.90305,0.925331,0.639839,0.667627,1.17594,1.40888,0.452865,0.305559,0.69094,0.680949,0.845342,0.635379,0.743951,2.30584,0.409304,0.842925,0.645155,0.388328,0.795576,1.21459,0.534793,0.439574,1.46099,1.96994,0.596053,0.855276,0.567465,0.469078,0.598234,0.777097,0.259059,0.63803,0.461452,0.726632,0.939121,0.808003,1.28131,0.645308,1.02504,0.951993,0.336258,1.29475,1.45259,2.14035,0.650353,0.892517,0.388177,2.0644,1.25741,0.941709,0.492369,1.14672,0.961293,1.11026,1.54311,1.91674,1.2037,1.75271,1.7986,0.502203,1.5923,1.45054,1.92922,1.87308,0.396746,4.1398,1.20029,0.73687,0.459024,1.14559,0.960908,0.498519,1.39759,0.977977,0.303648,0.381882,1.053,2.0169,1.63834,1.36973,1.23218,0.543775,0.642354,0.560075,1.14422,1.27663,1.05794,0.360456,0.569121,1.22626,1.27082,1.1798,1.09802,0.815119,1.16312,0.921547,0.743661,0.622396,0.703975,1.26794,0.684398,0.830777,1.58942,0.594137,1.66424,0.794219,1.10778,0.547323,1.44203,1.0504,0.850918,0.973172,1.70203,1.12965,0.930979,1.2374,1.48578,1.37952,1.37044,0.798812,1.50051,0.969553,1.65144,0.372828,0.788803,0.843556,1.60823,2.47382,2.06967,1.57016,0.932872,1.27296,1.09989,0.883164,1.08214,2.31409,0.773313,1.33389,0.318511,2.79286,1.37083,0.481626,0.941179,1.78371,1.03563,0.624795,0.744018,0.710709,1.56892,1.35169,1.19946,0.714443,1.11698,0.960047,0.524529,0.936473,0.951408
}}
}}

Revision as of 15:59, 26 November 2012


Full id: C3211_rhabdomyosarcoma_neuroblastoma_merkel_small_thalamus_smooth_diencephalon



Phase1 CAGE Peaks

Hg19::chr11:94473567..94473660,+p@chr11:94473567..94473660
+
Hg19::chr11:94473668..94473693,+p@chr11:94473668..94473693
+
Hg19::chr11:94473701..94473744,+p@chr11:94473701..94473744
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
neural cell9.98e-0725
Uber Anatomy
Ontology termp-valuen
nervous system2.35e-3889
ectoderm-derived structure3.16e-36171
ectoderm3.16e-36171
presumptive ectoderm3.16e-36171
central nervous system1.61e-3481
neural tube1.41e-3256
neural rod1.41e-3256
future spinal cord1.41e-3256
neural keel1.41e-3256
neurectoderm6.32e-3286
regional part of nervous system1.08e-3053
regional part of brain1.08e-3053
neural plate8.08e-3082
presumptive neural plate8.08e-3082
brain2.00e-2968
future brain2.00e-2968
organ system subdivision4.47e-27223
adult organism1.00e-26114
regional part of forebrain6.94e-2541
forebrain6.94e-2541
anterior neural tube6.94e-2541
future forebrain6.94e-2541
ecto-epithelium2.35e-24104
structure with developmental contribution from neural crest1.12e-22132
pre-chordal neural plate6.25e-2261
telencephalon5.39e-2134
brain grey matter6.25e-2134
gray matter6.25e-2134
cerebral hemisphere7.56e-2032
regional part of telencephalon2.15e-1932
anatomical cluster4.15e-17373
organ part2.02e-15218
cerebral cortex1.70e-1425
pallium1.70e-1425
regional part of cerebral cortex6.82e-1322
organ5.36e-12503
neocortex9.25e-1220
multi-tissue structure1.12e-11342
multi-cellular organism2.20e-11656
embryo9.08e-11592
anatomical system8.21e-10624
anatomical group1.09e-09625
developing anatomical structure2.09e-09581
cell layer7.93e-09309
posterior neural tube8.77e-0915
chordal neural plate8.77e-0915
germ layer1.03e-08560
germ layer / neural crest1.03e-08560
embryonic tissue1.03e-08560
presumptive structure1.03e-08560
germ layer / neural crest derived structure1.03e-08560
epiblast (generic)1.03e-08560
embryonic structure1.03e-08564
epithelium4.14e-08306
neural nucleus4.96e-089
nucleus of brain4.96e-089
basal ganglion8.94e-089
nuclear complex of neuraxis8.94e-089
aggregate regional part of brain8.94e-089
collection of basal ganglia8.94e-089
cerebral subcortex8.94e-089
segmental subdivision of nervous system9.55e-0813
anatomical conduit1.18e-07240
segmental subdivision of hindbrain4.82e-0712
hindbrain4.82e-0712
presumptive hindbrain4.82e-0712
tube8.35e-07192


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
ZNF263#1012738.221841637010680.001799043925565870.0108978799688054



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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