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Coexpression cluster:C1535

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Full id: C1535_occipital_gastrointestinal_carcinosarcoma_parietal_olfactory_amygdala_middle



Phase1 CAGE Peaks

Hg19::chr7:145869147..145869151,+p@chr7:145869147..145869151
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Hg19::chr7:145982691..145982726,+p@chr7:145982691..145982726
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Hg19::chr7:146019743..146019746,+p@chr7:146019743..146019746
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Hg19::chr7:146095297..146095301,+p@chr7:146095297..146095301
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Hg19::chr7:146161297..146161301,+p@chr7:146161297..146161301
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Hg19::chr7:146247520..146247525,+p@chr7:146247520..146247525
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube2.25e-6656
neural rod2.25e-6656
future spinal cord2.25e-6656
neural keel2.25e-6656
regional part of nervous system7.80e-6453
regional part of brain7.80e-6453
regional part of forebrain7.01e-5641
forebrain7.01e-5641
anterior neural tube7.01e-5641
future forebrain7.01e-5641
central nervous system4.04e-5481
brain grey matter1.69e-5234
gray matter1.69e-5234
brain3.72e-5268
future brain3.72e-5268
telencephalon4.47e-5234
cerebral hemisphere4.82e-5232
nervous system7.33e-5089
neural plate1.43e-4882
presumptive neural plate1.43e-4882
regional part of telencephalon4.69e-4832
neurectoderm5.08e-4886
regional part of cerebral cortex9.96e-4722
neocortex9.21e-4220
cerebral cortex1.36e-4025
pallium1.36e-4025
pre-chordal neural plate2.64e-3961
ecto-epithelium1.07e-37104
structure with developmental contribution from neural crest1.03e-31132
adult organism2.15e-28114
ectoderm-derived structure4.00e-26171
ectoderm4.00e-26171
presumptive ectoderm4.00e-26171
organ system subdivision2.83e-21223
tube6.72e-17192
gyrus9.04e-166
occipital lobe9.54e-145
parietal lobe2.53e-135
neural nucleus3.83e-139
nucleus of brain3.83e-139
posterior neural tube5.84e-1215
chordal neural plate5.84e-1215
anatomical conduit6.98e-12240
corpus striatum9.43e-114
striatum9.43e-114
ventral part of telencephalon9.43e-114
future corpus striatum9.43e-114
brainstem1.91e-106
anatomical cluster5.05e-10373
basal ganglion6.10e-109
nuclear complex of neuraxis6.10e-109
aggregate regional part of brain6.10e-109
collection of basal ganglia6.10e-109
cerebral subcortex6.10e-109
segmental subdivision of hindbrain1.31e-0912
hindbrain1.31e-0912
presumptive hindbrain1.31e-0912
temporal lobe1.68e-096
limbic system4.43e-095
telencephalic nucleus5.34e-097
organ part5.57e-09218
frontal cortex6.98e-093
segmental subdivision of nervous system8.79e-0913
caudate-putamen1.44e-083
dorsal striatum1.44e-083
pons1.76e-083
epithelium1.81e-08306
cell layer2.85e-08309
multi-tissue structure5.57e-08342
regional part of metencephalon3.98e-079
metencephalon3.98e-079
future metencephalon3.98e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.