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{{Coexpression_clusters
{
|full_id=C67_CD14_Monocytederived_Macrophage_dura_Dendritic_spleen_lung
|

Latest revision as of 10:22, 17 September 2013


Full id: C67_CD14_Monocytederived_Macrophage_dura_Dendritic_spleen_lung



Phase1 CAGE Peaks

Hg19::chr10:102051168..102051211,-p@chr10:102051168..102051211
-
Hg19::chr10:104486253..104486266,+p4@SFXN2
Hg19::chr10:105610418..105610432,-p@chr10:105610418..105610432
-
Hg19::chr10:433965..433992,-p6@DIP2C
Hg19::chr10:79289747..79289795,-p@chr10:79289747..79289795
-
Hg19::chr11:18720316..18720334,+p1@TMEM86A
Hg19::chr11:18720342..18720355,+p3@TMEM86A
Hg19::chr11:59950018..59950037,-p5@MS4A6A
Hg19::chr11:59950609..59950620,-p4@MS4A6A
Hg19::chr11:59950622..59950634,-p3@MS4A6A
Hg19::chr11:59951914..59951931,-p8@MS4A6A
Hg19::chr11:59951955..59951971,-p7@MS4A6A
Hg19::chr11:59952121..59952158,-p13@MS4A6A
Hg19::chr11:60048004..60048017,+p2@MS4A4A
Hg19::chr11:60048026..60048037,+p4@MS4A4A
Hg19::chr11:60048053..60048063,+p6@MS4A4A
Hg19::chr11:60048089..60048100,+p3@MS4A4A
Hg19::chr11:60048131..60048154,+p1@MS4A4A
Hg19::chr11:71927818..71927845,+p1@FOLR2
Hg19::chr11:74862080..74862089,+p7@SLCO2B1
Hg19::chr11:74862100..74862137,+p2@SLCO2B1
Hg19::chr11:74862140..74862159,+p1@SLCO2B1
Hg19::chr11:74873772..74873777,+p@chr11:74873772..74873777
+
Hg19::chr11:76886293..76886345,+p@chr11:76886293..76886345
+
Hg19::chr11:76886346..76886360,+p@chr11:76886346..76886360
+
Hg19::chr11:76886405..76886416,+p@chr11:76886405..76886416
+
Hg19::chr11:914717..914721,-p14@CHID1
Hg19::chr11:914789..914805,-p7@CHID1
Hg19::chr11:915012..915016,-p4@CHID1
Hg19::chr11:933519..933549,+p3@AP2A2
Hg19::chr11:933555..933565,+p7@AP2A2
Hg19::chr12:108733078..108733111,-p1@CMKLR1
Hg19::chr12:111752879..111752896,-p@chr12:111752879..111752896
-
Hg19::chr12:7649491..7649504,-p@chr12:7649491..7649504
-
Hg19::chr12:7649611..7649619,+p@chr12:7649611..7649619
+
Hg19::chr12:7653014..7653018,-p@chr12:7653014..7653018
-
Hg19::chr12:7653927..7653941,-p@chr12:7653927..7653941
-
Hg19::chr12:7653957..7653979,-p@chr12:7653957..7653979
-
Hg19::chr12:7655329..7655334,-p3@CD163
Hg19::chr12:7656133..7656168,-p@chr12:7656133..7656168
-
Hg19::chr12:7656345..7656356,-p2@CD163
Hg19::chr12:7656357..7656379,-p1@CD163
Hg19::chr12:7727849..7727866,-p@chr12:7727849..7727866
-
Hg19::chr12:7727871..7727893,-p@chr12:7727871..7727893
-
Hg19::chr13:49050561..49050578,+p8@RB1
Hg19::chr13:49050580..49050636,+p5@RB1
Hg19::chr14:21250247..21250257,+p9@RNASE6
Hg19::chr14:21269623..21269643,+p@chr14:21269623..21269643
+
Hg19::chr14:21269714..21269754,-p@chr14:21269714..21269754
-
Hg19::chr14:21270021..21270056,+p@chr14:21270021..21270056
+
Hg19::chr14:21270039..21270054,-p8@RNASE1
Hg19::chr14:21270074..21270116,-p5@RNASE1
Hg19::chr14:21270123..21270135,-p6@RNASE1
Hg19::chr14:21270158..21270175,-p9@RNASE1
Hg19::chr14:21270995..21271013,-p1@RNASE1
Hg19::chr14:21271019..21271030,-p3@RNASE1
Hg19::chr14:21271129..21271133,+p@chr14:21271129..21271133
+
Hg19::chr15:21941646..21941653,-p@chr15:21941646..21941653
-
Hg19::chr15:21941695..21941698,-p@chr15:21941695..21941698
-
Hg19::chr15:50405493..50405509,-p9@ATP8B4
Hg19::chr15:50405514..50405546,-p3@ATP8B4
Hg19::chr15:50405560..50405583,-p4@ATP8B4
Hg19::chr15:79288472..79288475,-p@chr15:79288472..79288475
-
Hg19::chr15:97318756..97318792,+p@chr15:97318756..97318792
+
Hg19::chr16:19702589..19702620,+p3@C16orf62
Hg19::chr16:22825475..22825496,+p1@HS3ST2
Hg19::chr16:22853400..22853404,+p@chr16:22853400..22853404
+
Hg19::chr16:22873614..22873618,+p@chr16:22873614..22873618
+
Hg19::chr16:72159246..72159270,-p1@PMFBP1
Hg19::chr17:29281302..29281321,+p6@ADAP2
Hg19::chr17:34391625..34391638,+p1@CCL18
Hg19::chr17:34397827..34397839,+p@chr17:34397827..34397839
+
Hg19::chr17:34397863..34397878,+p@chr17:34397863..34397878
+
Hg19::chr17:34398465..34398476,+p@chr17:34398465..34398476
+
Hg19::chr17:34398488..34398499,+p@chr17:34398488..34398499
+
Hg19::chr17:34398503..34398539,-p@chr17:34398503..34398539
-
Hg19::chr17:34398808..34398833,-p@chr17:34398808..34398833
-
Hg19::chr17:38121772..38121789,+p3@GSDMA
Hg19::chr17:38125787..38125800,+p@chr17:38125787..38125800
+
Hg19::chr17:38128814..38128833,+p@chr17:38128814..38128833
+
Hg19::chr17:66819004..66819024,+p@chr17:66819004..66819024
+
Hg19::chr17:66819028..66819037,+p@chr17:66819028..66819037
+
Hg19::chr17:78261736..78261799,+p2@RNF213
Hg19::chr17:78261803..78261813,+p8@RNF213
Hg19::chr18:6256778..6256791,+p1@uc002knb.2
Hg19::chr19:11687625..11687648,-p@chr19:11687625..11687648
-
Hg19::chr19:11688500..11688523,-p3@ACP5
Hg19::chr19:11688628..11688640,+p@chr19:11688628..11688640
+
Hg19::chr19:4229263..4229321,+p2@EBI3
Hg19::chr19:54761067..54761076,-p3@LILRB5
Hg19::chr19:54761080..54761146,-p1@LILRB5
Hg19::chr19:54761148..54761169,-p2@LILRB5
Hg19::chr19:54846597..54846601,+p@chr19:54846597..54846601
+
Hg19::chr1:112024304..112024309,-p@chr1:112024304..112024309
-
Hg19::chr1:112031415..112031459,-p1@ADORA3
Hg19::chr1:112031479..112031490,-p7@ADORA3
Hg19::chr1:112031517..112031529,-p8@ADORA3
Hg19::chr1:112031531..112031541,-p11@ADORA3
Hg19::chr1:112032329..112032358,-p4@ADORA3
Hg19::chr1:112032365..112032366,-p19@ADORA3
Hg19::chr1:112032375..112032406,-p5@ADORA3
Hg19::chr1:112046217..112046228,-p9@ADORA3
Hg19::chr1:112046243..112046277,-p3@ADORA3
Hg19::chr1:112046289..112046341,-p2@ADORA3
Hg19::chr1:112046476..112046490,-p13@ADORA3
Hg19::chr1:112047652..112047669,-p@chr1:112047652..112047669
-
Hg19::chr1:112047688..112047699,-p@chr1:112047688..112047699
-
Hg19::chr1:153330693..153330704,+p4@S100A9
Hg19::chr1:183774240..183774270,+p1@RGL1
Hg19::chr1:183774285..183774294,+p5@RGL1
Hg19::chr1:183774356..183774374,+p3@RGL1
Hg19::chr1:219632710..219632742,-p@chr1:219632710..219632742
-
Hg19::chr1:223350243..223350247,+p@chr1:223350243..223350247
+
Hg19::chr1:22962948..22962961,+p4@C1QA
Hg19::chr1:22963102..22963132,+p1@C1QA
Hg19::chr1:22963133..22963149,+p2@C1QA
Hg19::chr1:22963158..22963176,+p3@C1QA
Hg19::chr1:22964110..22964132,+p5@C1QA
Hg19::chr1:22965539..22965550,+p@chr1:22965539..22965550
+
Hg19::chr1:22965577..22965594,-p2@CU688829
Hg19::chr1:22965627..22965636,+p@chr1:22965627..22965636
+
Hg19::chr1:22970119..22970135,+p1@C1QC
Hg19::chr1:22970487..22970507,+p3@C1QC
Hg19::chr1:22970524..22970560,+p2@C1QC
Hg19::chr1:22970588..22970599,+p4@C1QC
Hg19::chr1:22973754..22973778,+p@chr1:22973754..22973778
+
Hg19::chr1:22973822..22973834,+p@chr1:22973822..22973834
+
Hg19::chr1:22973902..22973937,+p@chr1:22973902..22973937
+
Hg19::chr1:22973918..22973964,-p1@CU679234
Hg19::chr1:22973960..22973973,+p@chr1:22973960..22973973
+
Hg19::chr1:22973979..22973997,+p@chr1:22973979..22973997
+
Hg19::chr1:22973985..22973997,-p2@CU679234
Hg19::chr1:22973999..22974041,+p@chr1:22973999..22974041
+
Hg19::chr1:22974069..22974089,+p@chr1:22974069..22974089
+
Hg19::chr1:22974092..22974109,+p@chr1:22974092..22974109
+
Hg19::chr1:22974134..22974213,+p@chr1:22974134..22974213
+
Hg19::chr1:22974247..22974259,+p@chr1:22974247..22974259
+
Hg19::chr1:22974264..22974270,+p@chr1:22974264..22974270
+
Hg19::chr1:22974301..22974317,+p@chr1:22974301..22974317
+
Hg19::chr1:22974403..22974423,+p@chr1:22974403..22974423
+
Hg19::chr1:22974446..22974456,+p@chr1:22974446..22974456
+
Hg19::chr1:22974497..22974515,+p@chr1:22974497..22974515
+
Hg19::chr1:22979582..22979590,+p5@C1QB
Hg19::chr1:22979661..22979663,+p8@C1QB
Hg19::chr1:22979676..22979692,+p3@C1QB
Hg19::chr1:22979694..22979772,+p1@C1QB
Hg19::chr1:22985947..22985959,+p16@C1QB
Hg19::chr1:22985967..22985978,+p15@C1QB
Hg19::chr1:22985979..22985996,+p12@C1QB
Hg19::chr1:22986001..22986054,+p4@C1QB
Hg19::chr1:22986068..22986079,+p13@C1QB
Hg19::chr1:22987297..22987325,+p9@C1QB
Hg19::chr1:22987383..22987394,+p10@C1QB
Hg19::chr1:22987400..22987432,+p6@C1QB
Hg19::chr1:22987434..22987553,+p2@C1QB
Hg19::chr1:22987498..22987528,-p@chr1:22987498..22987528
-
Hg19::chr1:22987549..22987612,-p@chr1:22987549..22987612
-
Hg19::chr1:22987557..22987581,+p7@C1QB
Hg19::chr1:22987587..22987601,+p14@C1QB
Hg19::chr1:22987769..22987782,+p11@C1QB
Hg19::chr1:22987795..22987818,-p@chr1:22987795..22987818
-
Hg19::chr1:22987819..22987832,-p@chr1:22987819..22987832
-
Hg19::chr1:24194771..24194851,-p1@FUCA1
Hg19::chr1:78050720..78050734,-p9@ZZZ3
Hg19::chr20:25300539..25300555,-p@chr20:25300539..25300555
-
Hg19::chr20:3287808..3287861,-p@chr20:3287808..3287861
-
Hg19::chr20:3321190..3321215,-p7@C20orf194
Hg19::chr20:3689691..3689692,-p@chr20:3689691..3689692
-
Hg19::chr20:3693196..3693253,-p@chr20:3693196..3693253
-
Hg19::chr20:3693276..3693290,-p@chr20:3693276..3693290
-
Hg19::chr21:45543982..45544017,+p@chr21:45543982..45544017
+
Hg19::chr22:31003100..31003111,+p8@TCN2
Hg19::chr22:31003133..31003138,+p10@TCN2
Hg19::chr22:31003142..31003153,+p6@TCN2
Hg19::chr22:31003154..31003188,+p1@TCN2
Hg19::chr22:31003190..31003208,+p3@TCN2
Hg19::chr22:31003217..31003228,+p9@TCN2
Hg19::chr22:31003229..31003252,+p4@TCN2
Hg19::chr22:31003261..31003302,+p2@TCN2
Hg19::chr22:44568825..44568837,+p12@PARVG
Hg19::chr22:44568847..44568879,+p7@PARVG
Hg19::chr2:113999397..113999413,-p17@PAX8
Hg19::chr2:119726672..119726699,+p@chr2:119726672..119726699
+
Hg19::chr2:119726719..119726744,+p@chr2:119726719..119726744
+
Hg19::chr2:169926030..169926035,+p10@DHRS9
Hg19::chr2:206547765..206547823,+p4@NRP2
Hg19::chr2:218771554..218771570,-p@chr2:218771554..218771570
-
Hg19::chr2:219196764..219196774,+p@chr2:219196764..219196774
+
Hg19::chr2:25873079..25873089,-p23@DTNB
Hg19::chr2:29446678..29446695,-p3@ALK
Hg19::chr2:69732960..69732981,-p@chr2:69732960..69732981
-
Hg19::chr2:70262097..70262104,-p@chr2:70262097..70262104
-
Hg19::chr2:70262106..70262128,-p@chr2:70262106..70262128
-
Hg19::chr2:70262152..70262160,-p@chr2:70262152..70262160
-
Hg19::chr2:99385321..99385328,-p@chr2:99385321..99385328
-
Hg19::chr2:99389379..99389390,-p@chr2:99389379..99389390
-
Hg19::chr3:11349970..11349981,+p8@ATG7
Hg19::chr3:126666514..126666542,+p@chr3:126666514..126666542
+
Hg19::chr3:158537329..158537341,+p5@MFSD1
Hg19::chr3:158537344..158537353,+p18@MFSD1
Hg19::chr3:158537430..158537441,+p6@MFSD1
Hg19::chr3:158537454..158537484,+p3@MFSD1
Hg19::chr3:52514172..52514193,+p4@NISCH
Hg19::chr3:52525071..52525085,+p15@NISCH
Hg19::chr3:52529298..52529302,-p@chr3:52529298..52529302
-
Hg19::chr3:52529346..52529362,+p1@STAB1
Hg19::chr3:52529379..52529390,+p2@STAB1
Hg19::chr3:52529399..52529410,+p3@STAB1
Hg19::chr3:52537033..52537050,+p@chr3:52537033..52537050
+
Hg19::chr3:52537839..52537870,+p@chr3:52537839..52537870
+
Hg19::chr3:52558504..52558511,-p@chr3:52558504..52558511
-
Hg19::chr3:52716193..52716220,-p@chr3:52716193..52716220
-
Hg19::chr3:9151239..9151246,-p@chr3:9151239..9151246
-
Hg19::chr3:9151250..9151261,-p@chr3:9151250..9151261
-
Hg19::chr3:9151271..9151285,-p@chr3:9151271..9151285
-
Hg19::chr3:9151304..9151311,-p@chr3:9151304..9151311
-
Hg19::chr4:124425350..124425365,+p@chr4:124425350..124425365
+
Hg19::chr4:124425394..124425404,+p@chr4:124425394..124425404
+
Hg19::chr4:57570137..57570149,-p@chr4:57570137..57570149
-
Hg19::chr5:149460471..149460494,-p6@CSF1R
Hg19::chr5:150827209..150827231,+p3@SLC36A1
Hg19::chr5:150873498..150873509,+p@chr5:150873498..150873509
+
Hg19::chr5:150873510..150873548,+p@chr5:150873510..150873548
+
Hg19::chr5:150873557..150873562,+p@chr5:150873557..150873562
+
Hg19::chr5:150875782..150875790,+p@chr5:150875782..150875790
+
Hg19::chr5:35195338..35195352,-p6@PRLR
Hg19::chr5:42887498..42887508,-p14@SEPP1
Hg19::chr5:42887509..42887533,-p12@SEPP1
Hg19::chr5:53987781..53987790,+p@chr5:53987781..53987790
+
Hg19::chr5:72251353..72251398,+p6@FCHO2
Hg19::chr5:72251857..72251908,+p1@FCHO2
Hg19::chr5:72252545..72252569,-p@chr5:72252545..72252569
-
Hg19::chr5:76254428..76254466,+p7@CRHBP
Hg19::chr6:109669625..109669629,+p@chr6:109669625..109669629
+
Hg19::chr6:133007791..133007805,-p@chr6:133007791..133007805
-
Hg19::chr6:133119727..133119814,-p1@C6orf192
Hg19::chr6:32918586..32918597,-p@chr6:32918586..32918597
-
Hg19::chr6:56537133..56537166,-p@chr6:56537133..56537166
-
Hg19::chr6:6154374..6154375,-p@chr6:6154374..6154375
-
Hg19::chr6:6222293..6222308,-p4@F13A1
Hg19::chr6:6225026..6225035,-p@chr6:6225026..6225035
-
Hg19::chr6:6311753..6311755,-p@chr6:6311753..6311755
-
Hg19::chr6:6320887..6320902,-p1@F13A1
Hg19::chr6:7052167..7052179,+p@chr6:7052167..7052179
+
Hg19::chr6:7052195..7052268,+p@chr6:7052195..7052268
+
Hg19::chr7:134136504..134136522,-p10@AKR1B1
Hg19::chr7:23286379..23286401,+p1@GPNMB
Hg19::chr7:73240971..73240992,-p@chr7:73240971..73240992
-
Hg19::chr8:19093121..19093137,-p1@ENST00000518417
Hg19::chr8:24241955..24241966,+p3@ADAMDEC1
Hg19::chr8:24241969..24241999,+p2@ADAMDEC1
Hg19::chr8:24242010..24242026,+p1@ADAMDEC1
Hg19::chr8:24256905..24256914,+p@chr8:24256905..24256914
+
Hg19::chr8:24257731..24257740,+p@chr8:24257731..24257740
+
Hg19::chr8:59512733..59512738,-p14@NSMAF
Hg19::chr8:87354945..87355012,+p1@WWP1
Hg19::chr8:87355054..87355061,+p7@WWP1
Hg19::chr8:96207569..96207581,+p@chr8:96207569..96207581
+
Hg19::chr9:114047117..114047127,-p2@ENST00000426204
Hg19::chr9:114047148..114047161,-p1@ENST00000426204
Hg19::chr9:17415302..17415305,+p@chr9:17415302..17415305
+
Hg19::chrX:41548220..41548243,+p2@GPR34
Hg19::chrX:46639989..46640013,-p@chrX:46639989..46640013
-
Hg19::chrX:5644149..5644163,-p1@ENST00000456559
Hg19::chrX:5644164..5644176,-p2@ENST00000456559
Hg19::chrX:65241581..65241584,+p@chrX:65241581..65241584
+
Hg19::chrX:65252487..65252505,-p@chrX:65252487..65252505
-
Hg19::chrX:65253611..65253626,-p5@VSIG4
Hg19::chrX:65259856..65259863,-p4@VSIG4
Hg19::chrX:65259884..65259896,-p2@VSIG4
Hg19::chrX:65259900..65259909,-p3@VSIG4
Hg19::chrX:65259914..65259937,-p1@VSIG4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

p.valueFDRnGenesnPathwayName
1.37622863172383e-050.00435576361940593469Complement and coagulation cascades (KEGG):04610
5.50736472127791e-050.0116205395618964335Prion diseases (KEGG):05020
0.0002260473489044760.0238479953094222356Staphylococcus aureus infection (KEGG):05150
9.81038945513756e-060.00435576361940593320Complement Activation, Classical Pathway (Wikipathways):WP545
0.0001812978423751340.0229523068446919352Complement and Coagulation Cascades (Wikipathways):WP558
0.0001427384517159540.0225883599840498348{FCGR2B,50} (Static Module):NA



Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006954inflammatory response9.56206002322801e-06
GO:0009611response to wounding9.56206002322801e-06
GO:0006952defense response9.56206002322801e-06
GO:0009605response to external stimulus1.51938267980098e-05
GO:0005615extracellular space3.07428498430535e-05
GO:0016021integral to membrane0.000151314087487177
GO:0031224intrinsic to membrane0.000151314087487177
GO:0044421extracellular region part0.000207241943640159
GO:0044425membrane part0.000209503328142941
GO:0005602complement component C1 complex0.000209503328142941
GO:0006950response to stress0.000299723137100732
GO:0051239regulation of multicellular organismal process0.000393696681900918
GO:0006959humoral immune response0.000393696681900918
GO:0002460adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains0.000393696681900918
GO:0002250adaptive immune response0.000393696681900918
GO:0004871signal transducer activity0.000393696681900918
GO:0060089molecular transducer activity0.000393696681900918
GO:0002526acute inflammatory response0.000395684962589794
GO:0004872receptor activity0.000495322293292815
GO:0006958complement activation, classical pathway0.000514381499063508
GO:0002376immune system process0.000514381499063508
GO:0032501multicellular organismal process0.000564258340408766
GO:0002455humoral immune response mediated by circulating immunoglobulin0.000569596827366125
GO:0006956complement activation0.0011672377328113
GO:0002541activation of plasma proteins during acute inflammatory response0.0011672377328113
GO:0016020membrane0.00215367171501412
GO:0016064immunoglobulin mediated immune response0.00242847613547409
GO:0019724B cell mediated immunity0.00248221664204666
GO:0004888transmembrane receptor activity0.00250507284701867
GO:0007610behavior0.00326835384677842
GO:0007154cell communication0.0047357985380475
GO:0002253activation of immune response0.00538923454415271
GO:0007626locomotory behavior0.00538923454415271
GO:0002449lymphocyte mediated immunity0.00538923454415271
GO:0002443leukocyte mediated immunity0.00663145928499155
GO:0051180vitamin transport0.00688061779508333
GO:0005764lysosome0.00722821917545694
GO:0000323lytic vacuole0.00722821917545694
GO:0050778positive regulation of immune response0.00766383022390036
GO:0002684positive regulation of immune system process0.00773329668652567
GO:0042110T cell activation0.0107938376803848
GO:0050776regulation of immune response0.0107938376803848
GO:0005773vacuole0.0109283136920231
GO:0002682regulation of immune system process0.0109283136920231
GO:0004522pancreatic ribonuclease activity0.0115196513735499
GO:0051240positive regulation of multicellular organismal process0.0120480891577337
GO:0004714transmembrane receptor protein tyrosine kinase activity0.0131440773602587
GO:0002252immune effector process0.0132156995203932
GO:0045087innate immune response0.0143572766851503
GO:0016892endoribonuclease activity, producing 3'-phosphomonoesters0.0154083646696484
GO:0016894endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters0.017347446752541
GO:0044464cell part0.017593004475606
GO:0019199transmembrane receptor protein kinase activity0.0181262606177698
GO:0016044membrane organization and biogenesis0.0181430825109875
GO:0051179localization0.019163473646046
GO:0042129regulation of T cell proliferation0.0193135347634839
GO:0045113regulation of integrin biosynthetic process0.0193135347634839
GO:0008321Ral guanyl-nucleotide exchange factor activity0.0193135347634839
GO:0004925prolactin receptor activity0.0193135347634839
GO:0001613A3 adenosine receptor activity, G-protein coupled0.0193135347634839
GO:0042976activation of JAK protein0.0193135347634839
GO:0042977tyrosine phosphorylation of JAK2 protein0.0193135347634839
GO:0015235cobalamin transporter activity0.0193135347634839
GO:0001887selenium metabolic process0.0193135347634839
GO:0017047adrenocorticotropin-releasing hormone binding0.0193135347634839
GO:0042978ornithine decarboxylase activator activity0.0193135347634839
GO:0045112integrin biosynthetic process0.0193135347634839
GO:0006817phosphate transport0.0196701894133717
GO:0042330taxis0.0196701894133717
GO:0006935chemotaxis0.0196701894133717
GO:0042098T cell proliferation0.0210255164599685
GO:0046649lymphocyte activation0.0233380060715598
GO:0032944regulation of mononuclear cell proliferation0.0233380060715598
GO:0050670regulation of lymphocyte proliferation0.0233380060715598
GO:0051704multi-organism process0.0233380060715598
GO:0001608nucleotide receptor activity, G-protein coupled0.0235260909069615
GO:0045028purinergic nucleotide receptor activity, G-protein coupled0.0235260909069615
GO:0016502nucleotide receptor activity0.0239970802093195
GO:0001614purinergic nucleotide receptor activity0.0239970802093195
GO:0006955immune response0.0267025298125823
GO:0015808L-alanine transport0.0267025298125823
GO:0015816glycine transport0.0267025298125823
GO:0035238vitamin A biosynthetic process0.0267025298125823
GO:0042362fat-soluble vitamin biosynthetic process0.0267025298125823
GO:0045523interleukin-27 receptor binding0.0267025298125823
GO:0005011macrophage colony stimulating factor receptor activity0.0267025298125823
GO:0004996thyroid-stimulating hormone receptor activity0.0267025298125823
GO:0032328alanine transport0.0267025298125823
GO:0015193L-proline transmembrane transporter activity0.0267025298125823
GO:0015180L-alanine transmembrane transporter activity0.0267025298125823
GO:0032703negative regulation of interleukin-2 production0.0267025298125823
GO:00429059-cis-retinoic acid metabolic process0.0267025298125823
GO:0022858alanine transmembrane transporter activity0.0267025298125823
GO:0004839ubiquitin activating enzyme activity0.0267025298125823
GO:00429049-cis-retinoic acid biosynthetic process0.0267025298125823
GO:00470353-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity0.0267025298125823
GO:0045321leukocyte activation0.0267025298125823
GO:0032943mononuclear cell proliferation0.0276302758516279
GO:0046651lymphocyte proliferation0.0276302758516279
GO:0007275multicellular organismal development0.0314084254055507
GO:0050863regulation of T cell activation0.0334159177759208
GO:0006810transport0.0346048099817885
GO:0007171transmembrane receptor protein tyrosine kinase activation (dimerization)0.0346048099817885
GO:0046640regulation of alpha-beta T cell proliferation0.0346048099817885
GO:0006824cobalt ion transport0.0346048099817885
GO:0004944C5a anaphylatoxin receptor activity0.0346048099817885
GO:0004032aldehyde reductase activity0.0346048099817885
GO:0015824proline transport0.0346048099817885
GO:0045651positive regulation of macrophage differentiation0.0346048099817885
GO:0015087cobalt ion transmembrane transporter activity0.0346048099817885
GO:0046641positive regulation of alpha-beta T cell proliferation0.0346048099817885
GO:0046635positive regulation of alpha-beta T cell activation0.0346048099817885
GO:0001775cell activation0.0347772329378079
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway0.0349313275065516
GO:0048856anatomical structure development0.0356538591948679
GO:0004896hematopoietin/interferon-class (D200-domain) cytokine receptor activity0.0394749453533912
GO:0005887integral to plasma membrane0.0403396127586432
GO:0008285negative regulation of cell proliferation0.0403396127586432
GO:0051234establishment of localization0.0403396127586432
GO:0004521endoribonuclease activity0.0403396127586432
GO:0031226intrinsic to plasma membrane0.0403396127586432
GO:0005044scavenger receptor activity0.0403396127586432
GO:0004942anaphylatoxin receptor activity0.0403396127586432
GO:0043353enucleate erythrocyte differentiation0.0403396127586432
GO:0046633alpha-beta T cell proliferation0.0403396127586432
GO:0042448progesterone metabolic process0.0403396127586432
GO:0015187glycine transmembrane transporter activity0.0403396127586432
GO:0046634regulation of alpha-beta T cell activation0.0403396127586432
GO:0006811ion transport0.0417672115495474
GO:0007417central nervous system development0.0417672115495474
GO:0051249regulation of lymphocyte activation0.04215284769159
GO:0042127regulation of cell proliferation0.0444766695891267
GO:0008283cell proliferation0.0444766695891267
GO:0050865regulation of cell activation0.0444766695891267
GO:0048518positive regulation of biological process0.0444766695891267
GO:0007565female pregnancy0.0444766695891267
GO:0030669clathrin-coated endocytic vesicle membrane0.0444766695891267
GO:0030128clathrin coat of endocytic vesicle0.0444766695891267
GO:0002763positive regulation of myeloid leukocyte differentiation0.0444766695891267
GO:0015889cobalamin transport0.0444766695891267
GO:0030122AP-2 adaptor complex0.0444766695891267
GO:0031401positive regulation of protein modification process0.0444766695891267
GO:0042573retinoic acid metabolic process0.0444766695891267
GO:0045649regulation of macrophage differentiation0.0444766695891267
GO:0009791post-embryonic development0.0444766695891267
GO:0007165signal transduction0.0471348704335649
GO:0015698inorganic anion transport0.0486611446296584
GO:0042445hormone metabolic process0.0494865261413427
GO:0006026aminoglycan catabolic process0.0495684743890466
GO:0030666endocytic vesicle membrane0.0495684743890466
GO:0032663regulation of interleukin-2 production0.0495684743890466
GO:0042572retinol metabolic process0.0495684743890466
GO:0015884folic acid transport0.0495684743890466
GO:0004560alpha-L-fucosidase activity0.0495684743890466
GO:0006027glycosaminoglycan catabolic process0.0495684743890466
GO:0015928fucosidase activity0.0495684743890466



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
macrophage1.19e-176
adult endothelial progenitor cell5.39e-103
Uber Anatomy
Ontology termp-valuen
adult organism3.62e-58114
neural tube1.54e-1856
neural rod1.54e-1856
future spinal cord1.54e-1856
neural keel1.54e-1856
regional part of nervous system3.86e-1653
regional part of brain3.86e-1653
telencephalon7.96e-1434
brain grey matter8.82e-1434
gray matter8.82e-1434
central nervous system2.62e-1381
regional part of forebrain1.46e-1241
forebrain1.46e-1241
anterior neural tube1.46e-1241
future forebrain1.46e-1241
brain1.92e-1268
future brain1.92e-1268
neural plate5.07e-1282
presumptive neural plate5.07e-1282
nervous system2.22e-1189
neurectoderm3.45e-1186
regional part of telencephalon3.60e-1132
cerebral hemisphere5.38e-1132
brainstem3.24e-106
organ6.51e-10503
neural nucleus2.60e-099
nucleus of brain2.60e-099
organ system subdivision3.77e-09223
regional part of cerebral cortex1.55e-0822
pre-chordal neural plate2.43e-0861
ecto-epithelium2.88e-08104
structure with developmental contribution from neural crest2.92e-08132
pons1.09e-073
neocortex1.14e-0720
posterior neural tube2.07e-0715
chordal neural plate2.07e-0715
cerebral cortex2.44e-0725
pallium2.44e-0725
basal ganglion9.03e-079
nuclear complex of neuraxis9.03e-079
aggregate regional part of brain9.03e-079
collection of basal ganglia9.03e-079
cerebral subcortex9.03e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.11.86575e-10
MA0004.10.972818
MA0006.10.380582
MA0007.11.80923
MA0009.10.353757
MA0014.10
MA0017.10.45368
MA0019.10.00533345
MA0024.10.00149863
MA0025.11.37822
MA0027.11.02152
MA0028.10.00523383
MA0029.11.31081
MA0030.10.0941937
MA0031.10.195565
MA0038.10.17858
MA0040.10.77121
MA0041.10.279209
MA0042.10.342036
MA0043.10.19757
MA0046.10.0276608
MA0048.11.91382
MA0050.10.0150099
MA0051.10.00593477
MA0052.10.112818
MA0055.10.801295
MA0056.10
MA0057.11.77833e-05
MA0058.11.41993
MA0059.11.22038
MA0060.10.00168444
MA0061.10.119184
MA0063.10
MA0066.10.656761
MA0067.10.829606
MA0068.10.000585054
MA0069.11.37979
MA0070.116.8467
MA0071.10.756735
MA0072.10.0229149
MA0073.11.81423e-08
MA0074.10.479843
MA0076.10.0106039
MA0077.11.25254
MA0078.11.02203
MA0081.13.60384
MA0083.10.0962474
MA0084.10.426848
MA0087.10.697323
MA0088.10.00085328
MA0089.10
MA0090.10.492705
MA0091.13.59215
MA0092.10.0540412
MA0093.11.2797
MA0095.10
MA0098.10
MA0100.10.0804331
MA0101.10.622678
MA0103.11.43188
MA0105.10.00273135
MA0106.10.706335
MA0107.10.250841
MA0108.20.3111
MA0109.10
MA0111.10.0630628
MA0113.11.23648
MA0114.10.279241
MA0115.10.357375
MA0116.12.84518
MA0117.10.119543
MA0119.10.0637005
MA0122.10.142079
MA0124.10.125347
MA0125.10.626697
MA0130.10
MA0131.10.0841224
MA0132.10
MA0133.10
MA0135.12.50323
MA0136.10.534523
MA0139.10.000100208
MA0140.10.583956
MA0141.10.311134
MA0142.10.147701
MA0143.10.798086
MA0144.11.6842
MA0145.10.00897885
MA0146.11.62437e-06
MA0147.10.0763318
MA0148.11.63961
MA0149.11.96
MA0062.20.00582563
MA0035.20.0335509
MA0039.20
MA0138.20.453172
MA0002.20.121714
MA0137.21.97436
MA0104.20.0570651
MA0047.20.82242
MA0112.20.32371
MA0065.20.00422244
MA0150.10.204281
MA0151.10
MA0152.11.38886
MA0153.10.582347
MA0154.16.10889
MA0155.10.0094971
MA0156.10.16521
MA0157.10.30763
MA0158.10
MA0159.10.52902
MA0160.11.57329
MA0161.10
MA0162.15.78596e-16
MA0163.10.0163592
MA0164.10.159288
MA0080.23.20866
MA0018.20.545317
MA0099.20.00828146
MA0079.20
MA0102.20.923694
MA0258.11.63918
MA0259.10.0486172
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
MAFF#23764112.277459269813960.01011787060038380.037848787121082
MAFK#7975222.19197106261860.0005543326729990870.00473183081613009



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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