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Coexpression cluster:C1123

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Full id: C1123_medial_middle_parietal_occipital_paracentral_frontal_cerebral



Phase1 CAGE Peaks

  Short description
Hg19::chr10:79383809..79383833,+ p@chr10:79383809..79383833
+
Hg19::chr12:90987338..90987355,+ p@chr12:90987338..90987355
+
Hg19::chr2:175757825..175757858,- p@chr2:175757825..175757858
-
Hg19::chr2:86707317..86707337,+ p@chr2:86707317..86707337
+
Hg19::chr4:146071958..146071961,- p15@OTUD4
Hg19::chr8:27606125..27606134,- p6@CCDC25
Hg19::chr8:27606152..27606165,- p3@CCDC25


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


uberon_data


Uber Anatomy
Ontology termp-valuen
telencephalon2.36e-7834
brain grey matter5.23e-7834
gray matter5.23e-7834
regional part of forebrain5.22e-7741
forebrain5.22e-7741
anterior neural tube5.22e-7741
future forebrain5.22e-7741
neural tube3.80e-7656
neural rod3.80e-7656
future spinal cord3.80e-7656
neural keel3.80e-7656
cerebral hemisphere6.03e-7632
regional part of telencephalon1.30e-7532
regional part of nervous system9.08e-7553
regional part of brain9.08e-7553
central nervous system1.60e-6781
brain6.16e-6668
future brain6.16e-6668
nervous system2.24e-6089
regional part of cerebral cortex7.25e-5622
neocortex1.38e-5320
neural plate1.22e-5082
presumptive neural plate1.22e-5082
pre-chordal neural plate1.31e-5061
cerebral cortex4.62e-4925
pallium4.62e-4925
neurectoderm4.58e-4886
adult organism1.41e-47114
ecto-epithelium6.59e-39104
gyrus4.73e-376
structure with developmental contribution from neural crest1.50e-34132
basal ganglion2.78e-319
nuclear complex of neuraxis2.78e-319
aggregate regional part of brain2.78e-319
collection of basal ganglia2.78e-319
cerebral subcortex2.78e-319
neural nucleus3.83e-319
nucleus of brain3.83e-319
telencephalic nucleus6.64e-307
ectoderm-derived structure2.87e-29171
ectoderm2.87e-29171
presumptive ectoderm2.87e-29171
organ system subdivision8.58e-23223
frontal cortex1.88e-193
tube1.11e-18192
temporal lobe4.76e-146
corpus striatum5.08e-144
striatum5.08e-144
ventral part of telencephalon5.08e-144
future corpus striatum5.08e-144
anatomical conduit7.35e-14240
middle frontal gyrus1.08e-132
middle temporal gyrus1.22e-132
globus pallidus6.32e-132
pallidum6.32e-132
meninx1.45e-122
membrane organ1.45e-122
meningeal cluster1.45e-122
organ part6.57e-12218
parietal lobe9.06e-125
anatomical cluster2.34e-11373
limbic system3.63e-115
occipital lobe4.03e-115
epithelium1.11e-09306
cell layer1.56e-09309
brainstem5.46e-096
caudate-putamen6.59e-093
dorsal striatum6.59e-093
pons1.75e-083
multi-tissue structure4.68e-08342
paracentral gyrus1.44e-071
olfactory region1.85e-071
primary subdivision of skull1.85e-071
cranium1.85e-071
neurocranium1.85e-071
chondrocranium1.85e-071
cartilaginous neurocranium1.85e-071
head paraxial mesoderm1.85e-071
postcentral gyrus2.09e-071
nucleus accumbens2.67e-071
ventral striatum2.67e-071
putamen2.84e-071
insula3.02e-071
substantia nigra4.89e-071
midbrain nucleus4.89e-071
regional part of midbrain4.89e-071
midbrain4.89e-071
presumptive midbrain4.89e-071
midbrain neural tube4.89e-071
occipital pole5.84e-071
pole of cerebral hemisphere5.84e-071
dura mater6.97e-071
future meninx6.97e-071
ectomeninx6.97e-071
future dura mater6.97e-071


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.00215847
MA0004.10.502801
MA0006.10.341337
MA0007.10.483857
MA0009.10.973289
MA0014.10.0156227
MA0017.10.380797
MA0019.10.652951
MA0024.10.867125
MA0025.12.50576
MA0027.12.59001
MA0028.10.35747
MA0029.10.886702
MA0030.10.875089
MA0031.10.809638
MA0038.10.60704
MA0040.10.892629
MA0041.10.521615
MA0042.11.22641
MA0043.10.973609
MA0046.10.962263
MA0048.10.382278
MA0050.10.490116
MA0051.10.602745
MA0052.10.896548
MA0055.11.01052
MA0056.10
MA0057.10.115382
MA0058.10.406232
MA0059.10.404929
MA0060.10.224688
MA0061.10.198335
MA0063.10
MA0066.10.607474
MA0067.11.29359
MA0068.10.162298
MA0069.10.958358
MA0070.10.947018
MA0071.10.567661
MA0072.10.942461
MA0073.10.000265001
MA0074.10.60198
MA0076.10.422297
MA0077.10.934645
MA0078.10.703614
MA0081.10.405093
MA0083.10.980893
MA0084.11.48179
MA0087.10.939982
MA0088.10.252594
MA0089.10
MA0090.11.11391
MA0091.10.505453
MA0092.10.467172
MA0093.10.344385
MA0095.10
MA0098.10
MA0100.10.621149
MA0101.10.347695
MA0103.10.332048
MA0105.10.104569
MA0106.10.648997
MA0107.10.274127
MA0108.20.806528
MA0109.10
MA0111.11.14351
MA0113.10.665691
MA0114.10.269076
MA0115.11.21667
MA0116.10.277571
MA0117.11.01134
MA0119.14.72973
MA0122.11.03753
MA0124.11.17486
MA0125.11.0901
MA0130.10
MA0131.10.722072
MA0132.10
MA0133.10
MA0135.11.00402
MA0136.10.614215
MA0139.10.186511
MA0140.10.564957
MA0141.10.403171
MA0142.10.777365
MA0143.10.66587
MA0144.10.254954
MA0145.10.0807715
MA0146.10.0127148
MA0147.10.281049
MA0148.10.528066
MA0149.10.555119
MA0062.20.193221
MA0035.20.564239
MA0039.20.00276064
MA0138.20.704862
MA0002.20.213296
MA0137.20.36398
MA0104.20.223944
MA0047.20.636643
MA0112.20.0758925
MA0065.20.0828768
MA0150.10.430951
MA0151.10
MA0152.10.571637
MA0153.11.07307
MA0154.10.102476
MA0155.10.534073
MA0156.10.36627
MA0157.10.749547
MA0158.10
MA0159.10.770207
MA0160.10.543522
MA0161.10
MA0162.10.0249953
MA0163.10.0167306
MA0164.10.678332
MA0080.20.344472
MA0018.20.650405
MA0099.20.572
MA0079.21.2885e-05
MA0102.21.51913
MA0258.10.245543
MA0259.10.289405
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.