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Coexpression cluster:C3158

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Full id: C3158_acute_CD133_granulocyte_brain_cerebellum_diencephalon_CD34



Phase1 CAGE Peaks

Hg19::chr11:47615858..47615865,-p9@C1QTNF4
Hg19::chr11:47615871..47615887,-p5@C1QTNF4
Hg19::chr11:47615898..47615948,-p2@C1QTNF4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neuron4.99e-076
neuroblast4.99e-076
electrically signaling cell4.99e-076
Uber Anatomy
Ontology termp-valuen
neural tube7.98e-6756
neural rod7.98e-6756
future spinal cord7.98e-6756
neural keel7.98e-6756
central nervous system5.39e-6681
regional part of nervous system1.15e-6153
regional part of brain1.15e-6153
nervous system8.65e-6089
brain3.36e-5468
future brain3.36e-5468
regional part of forebrain3.65e-4741
forebrain3.65e-4741
anterior neural tube3.65e-4741
future forebrain3.65e-4741
neural plate8.27e-4582
presumptive neural plate8.27e-4582
brain grey matter3.16e-4234
gray matter3.16e-4234
neurectoderm5.08e-4286
telencephalon6.93e-4234
cerebral hemisphere3.69e-3932
regional part of telencephalon1.08e-3832
adult organism2.07e-38114
ecto-epithelium3.18e-35104
regional part of cerebral cortex4.02e-3522
neocortex4.14e-3220
pre-chordal neural plate6.92e-3261
cerebral cortex2.96e-3025
pallium2.96e-3025
structure with developmental contribution from neural crest9.31e-30132
ectoderm-derived structure1.97e-27171
ectoderm1.97e-27171
presumptive ectoderm1.97e-27171
organ system subdivision3.73e-25223
posterior neural tube5.08e-2015
chordal neural plate5.08e-2015
segmental subdivision of hindbrain3.65e-1512
hindbrain3.65e-1512
presumptive hindbrain3.65e-1512
tube1.09e-14192
segmental subdivision of nervous system8.44e-1413
neural nucleus2.65e-139
nucleus of brain2.65e-139
basal ganglion6.73e-139
nuclear complex of neuraxis6.73e-139
aggregate regional part of brain6.73e-139
collection of basal ganglia6.73e-139
cerebral subcortex6.73e-139
temporal lobe8.15e-136
brainstem4.82e-126
anatomical cluster7.92e-12373
gyrus2.71e-116
anatomical conduit1.33e-10240
regional part of metencephalon2.18e-109
metencephalon2.18e-109
future metencephalon2.18e-109
parietal lobe5.87e-105
telencephalic nucleus7.81e-107
limbic system1.95e-095
epithelium4.99e-09306
cell layer8.64e-09309
corpus striatum1.26e-084
striatum1.26e-084
ventral part of telencephalon1.26e-084
future corpus striatum1.26e-084
multi-tissue structure2.54e-07342
embryo4.09e-07592
pons4.55e-073
caudate-putamen6.74e-073
dorsal striatum6.74e-073
diencephalon8.61e-077
future diencephalon8.61e-077


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.