FF:10846-111E9: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00004855 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007947;DRR008819;DRZ000244;DRZ001629;DRZ011594;DRZ012979 | ||
|ancestors_in_disease_facet=DOID: | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002048,UBERON:0002100,UBERON:0000483,UBERON:0000479,UBERON:0000064,UBERON:0004119,UBERON:0000466,UBERON:0000062,UBERON:0004111,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000063,UBERON:0004802,UBERON:0000025,UBERON:0005911,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000119,UBERON:0009569,UBERON:0005178,UBERON:0000072,UBERON:0005177,UBERON:0004807,UBERON:0000117,UBERON:0000171,UBERON:0000115,UBERON:0000464,UBERON:0005181,UBERON:0010317,UBERON:0000065,UBERON:0000170,UBERON:0001004,UBERON:0002224,UBERON:0000915 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000076,CL:0000213,CL:0000215,CL:0000082,CL:0000255,CL:0000077 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:0050615,DOID:162,DOID:14566,DOID:0050687,DOID:1324,DOID:305 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0100353,FF:0101120,FF:0100762,FF:0102553,FF:0102424,FF:0103008 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score=chr11:61520075..61520136,+!p1@C11orf9!1.84!140.06!C11orf9;;chr15:83953397..83953425,-!p1@BNC1!1.76!64.63!BNC1;;chr17:26697276..26697303,-!p2@SEBOX,p2@VTN!1.55!34.53!SEBOX;;chr6:10415276..10415341,-!p2@TFAP2A!1.53!39.93!TFAP2A;;chr17:26697304..26697335,-!p1@SEBOX,p1@VTN!1.50!30.67!SEBOX;;chr7:27153454..27153469,-!p2@HOXA3!1.38!22.96!HOXA3;;chr11:32457075..32457095,-!p1@WT1!1.33!20.26!WT1;;chr18:19749541..19749557,+!p1@GATA6!1.32!61.73!GATA6;;chr6:10412600..10412637,-!p1@TFAP2A!1.32!32.80!TFAP2A;;chr8:37963466..37963506,+!p3@ASH2L!1.27!21.80!ASH2L;;chr4:87857474..87857489,+!p7@AFF1!1.21!26.24!AFF1;;chr6:34204921..34204939,+!p3@HMGA1!1.14!385.06!HMGA1;;chr18:19749386..19749404,+!p2@GATA6!1.13!17.94!GATA6;;chr6:10412392..10412409,-!p4@TFAP2A!1.12!14.08!TFAP2A;;chr11:65667884..65667895,-!p2@FOSL1!1.11!45.72!FOSL1;;chr11:65686802..65686818,+!p6@DRAP1!1.11!20.83!DRAP1;;chr1:158985493..158985535,+!p4@IFI16!1.10!17.75!IFI16;;chr7:26191809..26191890,+!p1@NFE2L3!1.05!51.32!NFE2L3;;chr6:126240380..126240430,+!p2@NCOA7!1.05!26.62!NCOA7;;chr8:11561684..11561751,+!p1@GATA4!1.04!10.03!GATA4;;chr12:80084167..80084197,-!p5@PAWR!1.02!22.76!PAWR;;chr15:67418047..67418093,+!p4@SMAD3!1.01!11.77!SMAD3;;chr16:67881588..67881612,-!p2@CENPT!1.00!12.54!CENPT;;chrY:2803415..2803468,+!p1@ZFY!1.00!9.07!ZFY;;chr8:106330656..106330684,+!p1@ZFPM2!0.98!23.15!ZFPM2;;chr7:101917447..101917479,+!p4@CUX1!0.97!8.30!CUX1;;chr11:65687243..65687276,+!p8@DRAP1!0.95!10.80!DRAP1;;chr11:120107344..120107351,+!p1@POU2F3!0.95!9.65!POU2F3;;chr15:67418177..67418204,+!p9@SMAD3!0.95!7.91!SMAD3;;chr11:65667846..65667868,-!p1@FOSL1!0.94!209.50!FOSL1;;chr7:27142290..27142310,-!p1@HOXA2!0.94!7.72!HOXA2;;chr17:26697257..26697268,-!p3@SEBOX,p3@VTN!0.94!7.72!SEBOX;;chr15:83953373..83953386,-!p2@BNC1!0.92!7.33!BNC1;;chr15:67418119..67418162,+!p5@SMAD3!0.90!7.72!SMAD3;;chr11:65686732..65686756,+!p2@DRAP1!0.89!29.90!DRAP1;;chr17:46622070..46622109,-!p1@HOXB2!0.89!15.63!HOXB2;;chr3:141121847..141121868,+!p5@ZBTB38!0.89!10.42!ZBTB38;;chr5:2751762..2751784,-!p1@IRX2!0.89!6.75!IRX2;;chr7:19157043..19157088,-!p2@TWIST1!0.88!17.36!TWIST1;;chr19:12203100..12203132,+!p1@ZNF788!0.87!13.50!ZNF788;;chr11:65687222..65687240,+!p7@DRAP1!0.86!8.10!DRAP1;;chr6:10415263..10415274,-!p8@TFAP2A!0.86!6.17!TFAP2A;;chr5:72744594..72744609,-!p1@FOXD1!0.85!29.71!FOXD1;;chr6:1389789..1389821,+!p1@FOXF2!0.85!8.49!FOXF2;;chr5:134369905..134369972,-!p1@PITX1!0.84!9.26!PITX1;;chrY:21906594..21906622,-!p1@KDM5D!0.84!5.98!KDM5D;;chr6:19837592..19837621,+!p1@ID4!0.82!36.46!ID4;;chr18:19749517..19749531,+!p3@GATA6!0.82!10.42!GATA6;;chr15:37392094..37392116,-!p6@MEIS2!0.82!7.14!MEIS2;;chr17:7493405..7493419,-!p1@SOX15!0.81!5.40!SOX15;;chr7:27183263..27183284,-!p2@HOXA5!0.81!5.40!HOXA5;;chr12:8186270..8186292,+!p3@FOXJ2!0.81!5.40!FOXJ2;;chr1:6479968..6479986,-!p1@HES2!0.81!5.40!HES2;;chr12:80084137..80084165,-!p10@PAWR!0.80!6.94!PAWR;;chr6:126240442..126240459,+!p4@NCOA7!0.80!6.94!NCOA7;;chr11:65687362..65687436,+!p3@DRAP1!0.79!25.66!DRAP1;;chr12:80084737..80084763,-!p3@PAWR!0.79!20.83!PAWR;;chr6:85473156..85473210,-!p2@TBX18!0.79!6.37!TBX18;;chr20:42295745..42295765,+!p1@MYBL2!0.77!87.00!MYBL2;;chr6:126240356..126240379,+!p7@NCOA7!0.76!5.98!NCOA7;;chr2:46524897..46524911,+!p2@EPAS1!0.75!13.89!EPAS1;;chr17:46622114..46622138,-!p4@HOXB2!0.75!7.33!HOXB2;;chr6:28321909..28321965,-!p3@ZNF323!0.75!4.63!ZNF323;;chr8:67525443..67525459,-!p2@MYBL1!0.74!6.94!MYBL1;;chr6:10412576..10412599,-!p5@TFAP2A!0.74!4.44!TFAP2A;;chr7:101917482..101917507,+!p6@CUX1!0.74!4.44!CUX1;;chr17:46703687..46703740,-!p1@HOXB9!0.74!4.44!HOXB9;;chr10:51572408..51572454,+!p3@NCOA4!0.73!28.55!NCOA4;;chr8:37963407..37963454,+!p2@ASH2L!0.72!13.89!ASH2L;;chr4:87857491..87857519,+!p10@AFF1!0.72!6.17!AFF1;;chr6:126240463..126240489,+!p6@NCOA7!0.72!4.82!NCOA7;;chr7:27153428..27153440,-!p3@HOXA3!0.72!4.24!HOXA3;;chr8:106330696..106330719,+!p2@ZFPM2!0.71!5.40!ZFPM2;;chr5:72744445..72744466,-!p2@FOXD1!0.70!7.14!FOXD1;;chr5:43067636..43067674,+!p6@ZNF131!0.70!5.59!ZNF131;;chr1:158985469..158985489,+!p7@IFI16!0.70!4.82!IFI16;;chr7:101917407..101917443,+!p3@CUX1!0.70!4.05!CUX1;;chr3:111314186..111314204,-!p1@ZBED2!0.70!4.05!ZBED2;;chr11:32456954..32456965,-!p4@WT1!0.70!4.05!WT1;;chr12:124873357..124873401,-!p1@NCOR2!0.69!51.89!NCOR2;;chr18:6414884..6414942,-!p1@L3MBTL4!0.69!5.02!L3MBTL4;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!0.69!3.86!HOXC5;;chr6:34204672..34204692,+!p1@HMGA1!0.68!493.09!HMGA1;;chr15:67358163..67358192,+!p1@SMAD3!0.68!101.47!SMAD3;;chr3:128206762..128206781,-!p2@GATA2!0.68!26.82!GATA2;;chr12:124873852..124873881,-!p3@NCOR2!0.68!26.24!NCOR2;;chr12:7079780..7079791,-!p2@PHB2!0.68!22.76!PHB2;;chr11:32457103..32457123,-!p3@WT1!0.67!3.67!WT1;;chr2:74730087..74730102,-!p4@LBX2!0.67!3.67!LBX2;;chr14:21566731..21566836,-!p1@ZNF219!0.66!44.18!ZNF219;;chr19:53193731..53193767,-!p1@ZNF83!0.66!36.85!ZNF83;;chr12:3068544..3068597,+!p1@TEAD4!0.65!24.31!TEAD4;;chr15:96874244..96874259,+!p5@NR2F2!0.65!9.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| 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| ||
|ffid_belonging_in_development=CL:0000222,UBERON:0001041,UBERON:0008947,UBERON:0002532,UBERON:0006595,UBERON:0010316 | |||
|fonse_cell_line=FF:0100353,FF:0101120,FF:0102424 | |fonse_cell_line=FF:0100353,FF:0101120,FF:0102424 | ||
|fonse_cell_line_closure=FF:0100353,FF:0101120,FF:0102424 | |fonse_cell_line_closure=FF:0100353,FF:0101120,FF:0102424 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H226.CNhs13062.10846-111E9.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H226.CNhs13062.10846-111E9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H226.CNhs13062.10846-111E9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H226.CNhs13062.10846-111E9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H226.CNhs13062.10846-111E9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10846-111E9 | |id=FF:10846-111E9 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0102424;;FF:0103008 | ||
|is_obsolete= | |||
|library_id=CNhs13062 | |||
|library_id_phase_based=2:CNhs13062 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10846 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10846 | |||
|name=mesothelioma cell line:NCI-H226 | |name=mesothelioma cell line:NCI-H226 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs13062,LSID1000,release012,COMPLETED | |profile_hcage=CNhs13062,LSID1000,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=111 | |rna_box=111 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 54: | Line 75: | ||
|rna_rin= | |rna_rin= | ||
|rna_sample_type=total RNA | |rna_sample_type=total RNA | ||
|rna_tube_id= | |rna_tube_id=1.11E+11 | ||
|rna_weight_ug=117.5865 | |rna_weight_ug=117.5865 | ||
|sample_age=unknown | |sample_age=unknown | ||
|sample_category=cell lines | |||
|sample_cell_catalog=CRL5826 | |sample_cell_catalog=CRL5826 | ||
|sample_cell_line=NCI-H226 | |sample_cell_line=NCI-H226 | ||
| Line 69: | Line 91: | ||
|sample_ethnicity=unknown | |sample_ethnicity=unknown | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;9.21170424464932e-247!GO:0043226;organelle;2.42554872623883e-201!GO:0043229;intracellular organelle;8.22587694719727e-201!GO:0043231;intracellular membrane-bound organelle;1.05559427083326e-194!GO:0043227;membrane-bound organelle;1.38882607697614e-194!GO:0005737;cytoplasm;2.15143766085224e-181!GO:0044422;organelle part;5.04585944317993e-158!GO:0044446;intracellular organelle part;2.10344392932573e-156!GO:0044444;cytoplasmic part;7.7652173953774e-128!GO:0032991;macromolecular complex;8.8548374516603e-112!GO:0030529;ribonucleoprotein complex;2.83682855453855e-98!GO:0044237;cellular metabolic process;4.55628389946672e-90!GO:0044238;primary metabolic process;9.24230028968095e-90!GO:0043170;macromolecule metabolic process;1.7460957691463e-86!GO:0005634;nucleus;1.02397977743456e-83!GO:0005515;protein binding;3.84120108066274e-82!GO:0003723;RNA binding;2.43297104109323e-79!GO:0044428;nuclear part;8.96523472453037e-78!GO:0043233;organelle lumen;1.54540124116063e-75!GO:0031974;membrane-enclosed lumen;1.54540124116063e-75!GO:0005739;mitochondrion;8.5148711800317e-65!GO:0005840;ribosome;5.47343762983616e-59!GO:0006412;translation;1.10125244261229e-56!GO:0006396;RNA processing;2.25205545768728e-56!GO:0043234;protein complex;1.39471208296495e-55!GO:0019538;protein metabolic process;1.56432152312402e-55!GO:0016043;cellular component organization and biogenesis;1.45148699868375e-54!GO:0031090;organelle membrane;6.04676768843949e-52!GO:0003735;structural constituent of ribosome;1.02165399009402e-51!GO:0043283;biopolymer metabolic process;3.01859996140125e-49!GO:0044267;cellular protein metabolic process;1.61055557711801e-48!GO:0044260;cellular macromolecule metabolic process;3.29078060518805e-48!GO:0033036;macromolecule localization;3.23262947203494e-46!GO:0031981;nuclear lumen;5.45371260353843e-46!GO:0015031;protein transport;6.79691779942253e-46!GO:0033279;ribosomal subunit;1.91056372885488e-44!GO:0044429;mitochondrial part;6.32742732881171e-44!GO:0043228;non-membrane-bound organelle;8.95235279375847e-44!GO:0043232;intracellular non-membrane-bound organelle;8.95235279375847e-44!GO:0044249;cellular biosynthetic process;1.70151134736177e-43!GO:0009058;biosynthetic process;4.48178962795811e-43!GO:0008104;protein localization;1.69649246918935e-42!GO:0045184;establishment of protein localization;2.62489528024718e-42!GO:0005829;cytosol;7.46042903581008e-42!GO:0010467;gene expression;7.46042903581008e-42!GO:0009059;macromolecule biosynthetic process;7.89029067763187e-42!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.82106168610575e-41!GO:0016071;mRNA metabolic process;1.20530610599286e-40!GO:0031967;organelle envelope;2.72786747892075e-40!GO:0031975;envelope;6.67588899235879e-40!GO:0008380;RNA splicing;8.97537599523781e-39!GO:0006996;organelle organization and biogenesis;3.35693816930875e-37!GO:0046907;intracellular transport;4.5156379419987e-37!GO:0006397;mRNA processing;9.86136616119034e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;3.00311576334377e-36!GO:0065003;macromolecular complex assembly;8.46451024439395e-36!GO:0006259;DNA metabolic process;8.11119550426091e-35!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.70637816310294e-33!GO:0022607;cellular component assembly;2.69784991010325e-32!GO:0006886;intracellular protein transport;4.64844119045596e-31!GO:0007049;cell cycle;1.716738716172e-29!GO:0000166;nucleotide binding;1.28078157156806e-28!GO:0005740;mitochondrial envelope;2.52288399509853e-27!GO:0005681;spliceosome;3.01008438787961e-27!GO:0044445;cytosolic part;6.13455486398649e-27!GO:0005654;nucleoplasm;6.8364172288802e-27!GO:0031966;mitochondrial membrane;1.93576828467781e-25!GO:0003676;nucleic acid binding;3.47359641358773e-25!GO:0019866;organelle inner membrane;6.09477785783537e-25!GO:0051649;establishment of cellular localization;9.17696676823802e-24!GO:0000278;mitotic cell cycle;9.45945326562565e-24!GO:0012505;endomembrane system;1.58232385333496e-23!GO:0022402;cell cycle process;1.66443388559997e-23!GO:0051641;cellular localization;2.81578738400012e-23!GO:0015934;large ribosomal subunit;3.84455876217771e-23!GO:0005743;mitochondrial inner membrane;4.28790339231582e-23!GO:0016462;pyrophosphatase activity;4.72517090734793e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.49095513138471e-23!GO:0017111;nucleoside-triphosphatase activity;7.13762448944296e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;8.72855221062348e-23!GO:0015935;small ribosomal subunit;2.07007978906589e-22!GO:0006119;oxidative phosphorylation;3.05413625172942e-22!GO:0044451;nucleoplasm part;1.92943370854072e-21!GO:0006974;response to DNA damage stimulus;2.18569469140163e-21!GO:0005730;nucleolus;3.74044958958093e-21!GO:0022618;protein-RNA complex assembly;2.96869446676422e-20!GO:0032553;ribonucleotide binding;3.40051938422744e-20!GO:0032555;purine ribonucleotide binding;3.40051938422744e-20!GO:0031980;mitochondrial lumen;8.26144439086945e-20!GO:0005759;mitochondrial matrix;8.26144439086945e-20!GO:0017076;purine nucleotide binding;1.25031165861603e-19!GO:0016874;ligase activity;1.76578076320965e-19!GO:0044455;mitochondrial membrane part;1.79086588542405e-19!GO:0005694;chromosome;1.87280858725479e-19!GO:0006457;protein folding;2.21715876113477e-19!GO:0000502;proteasome complex (sensu Eukaryota);8.11822089308691e-19!GO:0005524;ATP binding;1.32120096374237e-18!GO:0006281;DNA repair;1.42225423368106e-18!GO:0044427;chromosomal part;1.69568422930172e-18!GO:0032559;adenyl ribonucleotide binding;4.30619626677629e-18!GO:0000087;M phase of mitotic cell cycle;5.65889990105302e-18!GO:0007067;mitosis;1.04517141971918e-17!GO:0005783;endoplasmic reticulum;1.41397249721451e-17!GO:0022403;cell cycle phase;2.0892729304731e-17!GO:0044265;cellular macromolecule catabolic process;2.0892729304731e-17!GO:0030554;adenyl nucleotide binding;2.52270373986397e-17!GO:0042254;ribosome biogenesis and assembly;6.95834106732044e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);7.58971520953391e-17!GO:0016070;RNA metabolic process;7.92637458592829e-17!GO:0043285;biopolymer catabolic process;8.49139454012933e-17!GO:0006512;ubiquitin cycle;8.49139454012933e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;9.94613234820483e-17!GO:0019941;modification-dependent protein catabolic process;1.11271155275402e-16!GO:0043632;modification-dependent macromolecule catabolic process;1.11271155275402e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.14512360456043e-16!GO:0006511;ubiquitin-dependent protein catabolic process;1.21939012853638e-16!GO:0044257;cellular protein catabolic process;2.05388940417401e-16!GO:0008135;translation factor activity, nucleic acid binding;2.41425864029781e-16!GO:0044432;endoplasmic reticulum part;5.03008059446783e-16!GO:0009057;macromolecule catabolic process;1.07559515059457e-15!GO:0005761;mitochondrial ribosome;1.18163643338862e-15!GO:0000313;organellar ribosome;1.18163643338862e-15!GO:0005746;mitochondrial respiratory chain;1.404556057403e-15!GO:0006260;DNA replication;1.57875338194149e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.22510532661845e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;2.30291905642833e-15!GO:0000375;RNA splicing, via transesterification reactions;2.30291905642833e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.30291905642833e-15!GO:0030163;protein catabolic process;2.55239251339309e-15!GO:0051301;cell division;2.99118186652759e-15!GO:0006605;protein targeting;4.48408971486601e-15!GO:0048770;pigment granule;6.39623140299147e-15!GO:0042470;melanosome;6.39623140299147e-15!GO:0050136;NADH dehydrogenase (quinone) activity;1.25447040261501e-14!GO:0003954;NADH dehydrogenase activity;1.25447040261501e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.25447040261501e-14!GO:0008134;transcription factor binding;1.5237009914533e-14!GO:0044453;nuclear membrane part;2.79836663188368e-14!GO:0005794;Golgi apparatus;3.15206250976112e-14!GO:0051276;chromosome organization and biogenesis;3.15674168922731e-14!GO:0043412;biopolymer modification;3.63889407228005e-14!GO:0000279;M phase;5.13013728670439e-14!GO:0048193;Golgi vesicle transport;5.68125277489718e-14!GO:0009719;response to endogenous stimulus;7.00049052192698e-14!GO:0042623;ATPase activity, coupled;1.00963967202649e-13!GO:0051082;unfolded protein binding;1.1089959233057e-13!GO:0016887;ATPase activity;1.47138293122142e-13!GO:0005635;nuclear envelope;2.63735674965987e-13!GO:0031965;nuclear membrane;4.09854948116074e-13!GO:0003743;translation initiation factor activity;4.4534576766942e-13!GO:0042775;organelle ATP synthesis coupled electron transport;4.87844198488281e-13!GO:0042773;ATP synthesis coupled electron transport;4.87844198488281e-13!GO:0044248;cellular catabolic process;5.17578318119485e-13!GO:0051186;cofactor metabolic process;5.47255361311465e-13!GO:0000074;regulation of progression through cell cycle;7.74644776099702e-13!GO:0030964;NADH dehydrogenase complex (quinone);8.57991226743093e-13!GO:0045271;respiratory chain complex I;8.57991226743093e-13!GO:0005747;mitochondrial respiratory chain complex I;8.57991226743093e-13!GO:0016192;vesicle-mediated transport;9.43052488974166e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.00748012082123e-12!GO:0051726;regulation of cell cycle;1.03750038557886e-12!GO:0006399;tRNA metabolic process;1.07209709070505e-12!GO:0006413;translational initiation;1.47758856263285e-12!GO:0012501;programmed cell death;1.66681251678915e-12!GO:0006464;protein modification process;1.69762364340117e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.40205111888239e-12!GO:0006915;apoptosis;3.33245985807598e-12!GO:0005789;endoplasmic reticulum membrane;4.61381179912729e-12!GO:0005643;nuclear pore;1.0984192637939e-11!GO:0004386;helicase activity;1.36135831690047e-11!GO:0006364;rRNA processing;1.82969002570545e-11!GO:0016072;rRNA metabolic process;2.80075865360029e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.80075865360029e-11!GO:0008026;ATP-dependent helicase activity;3.61363927757147e-11!GO:0016604;nuclear body;5.35350670153487e-11!GO:0008219;cell death;5.93319670717772e-11!GO:0016265;death;5.93319670717772e-11!GO:0006913;nucleocytoplasmic transport;6.05081518641041e-11!GO:0043687;post-translational protein modification;1.00636961779524e-10!GO:0006461;protein complex assembly;1.22124845122973e-10!GO:0065002;intracellular protein transport across a membrane;1.40855213016713e-10!GO:0051169;nuclear transport;1.40855213016713e-10!GO:0006325;establishment and/or maintenance of chromatin architecture;1.45407420682599e-10!GO:0009259;ribonucleotide metabolic process;1.53319339902334e-10!GO:0008639;small protein conjugating enzyme activity;3.14040194004096e-10!GO:0006446;regulation of translational initiation;4.25503246555344e-10!GO:0006323;DNA packaging;4.34377529178294e-10!GO:0046930;pore complex;4.89871099349736e-10!GO:0006732;coenzyme metabolic process;5.57497224863941e-10!GO:0000785;chromatin;5.67961731584791e-10!GO:0050657;nucleic acid transport;5.81505840695518e-10!GO:0051236;establishment of RNA localization;5.81505840695518e-10!GO:0050658;RNA transport;5.81505840695518e-10!GO:0006163;purine nucleotide metabolic process;6.09580372084607e-10!GO:0006403;RNA localization;6.1986503381645e-10!GO:0008565;protein transporter activity;7.86962313837977e-10!GO:0004842;ubiquitin-protein ligase activity;7.90183669538733e-10!GO:0009055;electron carrier activity;9.82997331730099e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.66598954350097e-09!GO:0009260;ribonucleotide biosynthetic process;1.72842168321658e-09!GO:0006164;purine nucleotide biosynthetic process;1.75424508692924e-09!GO:0019787;small conjugating protein ligase activity;2.05151705677117e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.37167918796678e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.37167918796678e-09!GO:0004812;aminoacyl-tRNA ligase activity;2.37167918796678e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.37167918796678e-09!GO:0009150;purine ribonucleotide metabolic process;2.60171849115767e-09!GO:0003712;transcription cofactor activity;3.24482415309589e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.06239524759898e-09!GO:0065004;protein-DNA complex assembly;4.21026666489505e-09!GO:0043038;amino acid activation;5.12617433133097e-09!GO:0006418;tRNA aminoacylation for protein translation;5.12617433133097e-09!GO:0043039;tRNA aminoacylation;5.12617433133097e-09!GO:0009152;purine ribonucleotide biosynthetic process;7.23338931054122e-09!GO:0043067;regulation of programmed cell death;8.98956135002186e-09!GO:0003697;single-stranded DNA binding;9.47433913839178e-09!GO:0006366;transcription from RNA polymerase II promoter;9.70120088431711e-09!GO:0042981;regulation of apoptosis;9.92956346668023e-09!GO:0015986;ATP synthesis coupled proton transport;1.63552518110564e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.63552518110564e-08!GO:0048523;negative regulation of cellular process;2.09942005526497e-08!GO:0016607;nuclear speck;2.10067924474465e-08!GO:0009199;ribonucleoside triphosphate metabolic process;2.18442764163386e-08!GO:0006333;chromatin assembly or disassembly;2.61285466812932e-08!GO:0048475;coated membrane;2.66463668396159e-08!GO:0030117;membrane coat;2.66463668396159e-08!GO:0009141;nucleoside triphosphate metabolic process;2.73240745091829e-08!GO:0007005;mitochondrion organization and biogenesis;2.76711976732711e-08!GO:0009142;nucleoside triphosphate biosynthetic process;2.90238222091731e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.90238222091731e-08!GO:0006888;ER to Golgi vesicle-mediated transport;2.91998082351121e-08!GO:0051028;mRNA transport;3.96936195994327e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;4.10885357009982e-08!GO:0009144;purine nucleoside triphosphate metabolic process;4.10885357009982e-08!GO:0043566;structure-specific DNA binding;4.46397562513264e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.75114167475496e-08!GO:0016779;nucleotidyltransferase activity;4.82361496853882e-08!GO:0005839;proteasome core complex (sensu Eukaryota);4.85258692621843e-08!GO:0017038;protein import;4.92589629431329e-08!GO:0016881;acid-amino acid ligase activity;5.0695268172286e-08!GO:0005793;ER-Golgi intermediate compartment;5.32106494180753e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;5.53535665424861e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;5.53535665424861e-08!GO:0030532;small nuclear ribonucleoprotein complex;5.53620182031116e-08!GO:0015630;microtubule cytoskeleton;5.72022280885058e-08!GO:0030120;vesicle coat;6.63416237833967e-08!GO:0030662;coated vesicle membrane;6.63416237833967e-08!GO:0050794;regulation of cellular process;6.85979221843875e-08!GO:0051188;cofactor biosynthetic process;8.59251036933866e-08!GO:0005768;endosome;1.0737701540841e-07!GO:0009060;aerobic respiration;1.2032139576629e-07!GO:0009056;catabolic process;1.2032139576629e-07!GO:0043069;negative regulation of programmed cell death;1.39507289189913e-07!GO:0000775;chromosome, pericentric region;1.6268902312862e-07!GO:0046034;ATP metabolic process;2.18662812507674e-07!GO:0006754;ATP biosynthetic process;2.28301759150566e-07!GO:0006753;nucleoside phosphate metabolic process;2.28301759150566e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.31280857262971e-07!GO:0016740;transferase activity;2.70616062012262e-07!GO:0019829;cation-transporting ATPase activity;3.00548317951579e-07!GO:0043066;negative regulation of apoptosis;3.16592270449618e-07!GO:0005819;spindle;4.10162784259591e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;4.33433695595777e-07!GO:0044431;Golgi apparatus part;4.33433695595777e-07!GO:0004298;threonine endopeptidase activity;4.55449669286532e-07!GO:0006916;anti-apoptosis;4.89938484066125e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;4.91083642406229e-07!GO:0000245;spliceosome assembly;4.91083642406229e-07!GO:0048519;negative regulation of biological process;5.13400842818022e-07!GO:0051329;interphase of mitotic cell cycle;6.76263489587969e-07!GO:0051325;interphase;7.85842237502771e-07!GO:0007051;spindle organization and biogenesis;8.80009147481455e-07!GO:0043623;cellular protein complex assembly;9.45594733881867e-07!GO:0003924;GTPase activity;9.82401600795423e-07!GO:0051246;regulation of protein metabolic process;1.03324748704347e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.23432970179879e-06!GO:0045333;cellular respiration;1.2812209348375e-06!GO:0032446;protein modification by small protein conjugation;1.43888527653193e-06!GO:0016567;protein ubiquitination;1.52768811310606e-06!GO:0016568;chromatin modification;1.55799128486914e-06!GO:0045259;proton-transporting ATP synthase complex;1.94976887917557e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.12033899697081e-06!GO:0009117;nucleotide metabolic process;2.16721248628781e-06!GO:0015078;hydrogen ion transmembrane transporter activity;2.21022516618533e-06!GO:0006793;phosphorus metabolic process;2.42640239419938e-06!GO:0006796;phosphate metabolic process;2.42640239419938e-06!GO:0009108;coenzyme biosynthetic process;2.77675279439116e-06!GO:0005667;transcription factor complex;3.22198067445294e-06!GO:0045786;negative regulation of progression through cell cycle;3.82014953660895e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;3.9013338453524e-06!GO:0044440;endosomal part;4.08091885040618e-06!GO:0010008;endosome membrane;4.08091885040618e-06!GO:0003724;RNA helicase activity;4.37285665450462e-06!GO:0006261;DNA-dependent DNA replication;4.46740926458751e-06!GO:0016310;phosphorylation;4.4838798365108e-06!GO:0006334;nucleosome assembly;5.20958747117264e-06!GO:0006752;group transfer coenzyme metabolic process;5.41264749135851e-06!GO:0031988;membrane-bound vesicle;5.56637141862378e-06!GO:0005813;centrosome;5.90675574029252e-06!GO:0016787;hydrolase activity;6.04301945317905e-06!GO:0016023;cytoplasmic membrane-bound vesicle;6.88206395488326e-06!GO:0006099;tricarboxylic acid cycle;7.96180573807586e-06!GO:0046356;acetyl-CoA catabolic process;7.96180573807586e-06!GO:0016853;isomerase activity;8.55018261978596e-06!GO:0005762;mitochondrial large ribosomal subunit;9.92484895568124e-06!GO:0000315;organellar large ribosomal subunit;9.92484895568124e-06!GO:0005657;replication fork;1.12905807222954e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.16054078135995e-05!GO:0005815;microtubule organizing center;1.28574180702378e-05!GO:0000075;cell cycle checkpoint;1.36382698622689e-05!GO:0031497;chromatin assembly;1.43763359976076e-05!GO:0000139;Golgi membrane;1.5766366182727e-05!GO:0006084;acetyl-CoA metabolic process;1.59586290154136e-05!GO:0005788;endoplasmic reticulum lumen;1.7247083663325e-05!GO:0005798;Golgi-associated vesicle;1.73459698373812e-05!GO:0051427;hormone receptor binding;1.86308707208049e-05!GO:0006613;cotranslational protein targeting to membrane;2.03192938973039e-05!GO:0003714;transcription corepressor activity;2.04004517689147e-05!GO:0000151;ubiquitin ligase complex;2.09313578573337e-05!GO:0051170;nuclear import;2.14303339985598e-05!GO:0003899;DNA-directed RNA polymerase activity;2.42778039036889e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;2.44049983130191e-05!GO:0051187;cofactor catabolic process;2.84553091537106e-05!GO:0016491;oxidoreductase activity;3.26413191031584e-05!GO:0051168;nuclear export;3.77008729242415e-05!GO:0006606;protein import into nucleus;3.77207716396984e-05!GO:0007010;cytoskeleton organization and biogenesis;4.11091052938711e-05!GO:0035257;nuclear hormone receptor binding;4.21955835035572e-05!GO:0016564;transcription repressor activity;4.93651700984018e-05!GO:0008033;tRNA processing;5.46793236868241e-05!GO:0050789;regulation of biological process;5.96099298591071e-05!GO:0048522;positive regulation of cellular process;6.58402341375892e-05!GO:0044452;nucleolar part;6.64654460794689e-05!GO:0009109;coenzyme catabolic process;6.67657883073129e-05!GO:0031252;leading edge;6.68755429064933e-05!GO:0019843;rRNA binding;6.99142189330995e-05!GO:0006612;protein targeting to membrane;7.81660208430401e-05!GO:0000314;organellar small ribosomal subunit;8.28681394001757e-05!GO:0005763;mitochondrial small ribosomal subunit;8.28681394001757e-05!GO:0030867;rough endoplasmic reticulum membrane;8.82515772722471e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;8.85495560342598e-05!GO:0031982;vesicle;9.80934392438579e-05!GO:0005525;GTP binding;0.000111016415630605!GO:0003713;transcription coactivator activity;0.000112023715689147!GO:0043021;ribonucleoprotein binding;0.000116605253852573!GO:0003682;chromatin binding;0.000119015556911842!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000122573423042237!GO:0031410;cytoplasmic vesicle;0.000134022016650856!GO:0005770;late endosome;0.000138358069187993!GO:0008654;phospholipid biosynthetic process;0.000145831967605055!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000146422773096018!GO:0006302;double-strand break repair;0.000154475022759992!GO:0006414;translational elongation;0.000157008032982719!GO:0007088;regulation of mitosis;0.000157022027571473!GO:0008094;DNA-dependent ATPase activity;0.000158716604129865!GO:0051789;response to protein stimulus;0.00017367827914322!GO:0006986;response to unfolded protein;0.00017367827914322!GO:0019899;enzyme binding;0.000191702741110375!GO:0008186;RNA-dependent ATPase activity;0.000192725886103583!GO:0045454;cell redox homeostasis;0.000203623963840864!GO:0016563;transcription activator activity;0.000207315357947894!GO:0016363;nuclear matrix;0.000251577634547894!GO:0007059;chromosome segregation;0.000251577634547894!GO:0031324;negative regulation of cellular metabolic process;0.000262706048203726!GO:0006626;protein targeting to mitochondrion;0.000267576434931566!GO:0000776;kinetochore;0.000271482747624403!GO:0016859;cis-trans isomerase activity;0.00029439881328519!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000301488090165762!GO:0030036;actin cytoskeleton organization and biogenesis;0.000314461620606769!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000315318433574874!GO:0005769;early endosome;0.000325900902252364!GO:0003690;double-stranded DNA binding;0.00032781622189176!GO:0005905;coated pit;0.000338987624698972!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000339171539560863!GO:0033116;ER-Golgi intermediate compartment membrane;0.000339171539560863!GO:0016044;membrane organization and biogenesis;0.000340211702076892!GO:0003729;mRNA binding;0.000340553261050257!GO:0005048;signal sequence binding;0.000373089873618367!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000389308908833062!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000396438758719655!GO:0005885;Arp2/3 protein complex;0.00045138872266114!GO:0003684;damaged DNA binding;0.00046642247531519!GO:0001726;ruffle;0.000467913313451942!GO:0004004;ATP-dependent RNA helicase activity;0.000523558188689238!GO:0007093;mitotic cell cycle checkpoint;0.000525248701093417!GO:0043681;protein import into mitochondrion;0.000556989256679384!GO:0008250;oligosaccharyl transferase complex;0.000579154864222877!GO:0000082;G1/S transition of mitotic cell cycle;0.000608633496152007!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000608633496152007!GO:0015399;primary active transmembrane transporter activity;0.000608633496152007!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000655863366230959!GO:0030659;cytoplasmic vesicle membrane;0.000682712781232832!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000685235196904601!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000710443474090663!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000795453219253007!GO:0006310;DNA recombination;0.000822671925278236!GO:0032561;guanyl ribonucleotide binding;0.000828616380418481!GO:0019001;guanyl nucleotide binding;0.000828616380418481!GO:0005684;U2-dependent spliceosome;0.000873202441186112!GO:0007052;mitotic spindle organization and biogenesis;0.000886868173242558!GO:0006091;generation of precursor metabolites and energy;0.000888275360212521!GO:0030118;clathrin coat;0.000958089885108939!GO:0007006;mitochondrial membrane organization and biogenesis;0.000958396646394771!GO:0018196;peptidyl-asparagine modification;0.000958396646394771!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.000958396646394771!GO:0004576;oligosaccharyl transferase activity;0.000963963515684887!GO:0006383;transcription from RNA polymerase III promoter;0.000991669399083187!GO:0015980;energy derivation by oxidation of organic compounds;0.00100029153553218!GO:0031968;organelle outer membrane;0.00105065597735946!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00106152632646141!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00106152632646141!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00106152632646141!GO:0030663;COPI coated vesicle membrane;0.00119689000375844!GO:0030126;COPI vesicle coat;0.00119689000375844!GO:0004674;protein serine/threonine kinase activity;0.00123726172738936!GO:0005773;vacuole;0.00124329169515242!GO:0019867;outer membrane;0.0012449567754948!GO:0005874;microtubule;0.00132569515075932!GO:0044433;cytoplasmic vesicle part;0.00135712377321049!GO:0009892;negative regulation of metabolic process;0.00139333035650029!GO:0048471;perinuclear region of cytoplasm;0.0014404573902429!GO:0051252;regulation of RNA metabolic process;0.0014404573902429!GO:0009165;nucleotide biosynthetic process;0.00144736833258471!GO:0006839;mitochondrial transport;0.00145546169409057!GO:0007243;protein kinase cascade;0.00148618765324219!GO:0030132;clathrin coat of coated pit;0.00149740689817446!GO:0006401;RNA catabolic process;0.00151629318544165!GO:0042802;identical protein binding;0.00154375997164886!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00155226417119295!GO:0030029;actin filament-based process;0.00155699470048227!GO:0000786;nucleosome;0.00163492517386372!GO:0030137;COPI-coated vesicle;0.00166267928144141!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0016746031876212!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00168562285997643!GO:0003678;DNA helicase activity;0.00172987866888385!GO:0006352;transcription initiation;0.00175570094271958!GO:0006402;mRNA catabolic process;0.00186531129306179!GO:0005791;rough endoplasmic reticulum;0.00199469383665128!GO:0012506;vesicle membrane;0.00221654618878327!GO:0016272;prefoldin complex;0.00223346644443713!GO:0043284;biopolymer biosynthetic process;0.00224572133028424!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00228732987053831!GO:0000059;protein import into nucleus, docking;0.00253408279345215!GO:0030658;transport vesicle membrane;0.00254591181707492!GO:0048518;positive regulation of biological process;0.00274159221725827!GO:0019222;regulation of metabolic process;0.00276218829298227!GO:0035258;steroid hormone receptor binding;0.00285259375756654!GO:0006891;intra-Golgi vesicle-mediated transport;0.00293001482022704!GO:0016481;negative regulation of transcription;0.00300779197538954!GO:0007050;cell cycle arrest;0.00303519787841998!GO:0048487;beta-tubulin binding;0.00304566106551845!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.00310034719090615!GO:0051920;peroxiredoxin activity;0.00310516791792817!GO:0008632;apoptotic program;0.00313376188413362!GO:0008022;protein C-terminus binding;0.00321243279033077!GO:0000049;tRNA binding;0.0033982456518223!GO:0031901;early endosome membrane;0.00341394226066087!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00363087447473861!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00363087447473861!GO:0008637;apoptotic mitochondrial changes;0.00367832267561304!GO:0030880;RNA polymerase complex;0.00371017887170339!GO:0030119;AP-type membrane coat adaptor complex;0.00379239558979539!GO:0008139;nuclear localization sequence binding;0.00386366824727416!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00391886613317603!GO:0003711;transcription elongation regulator activity;0.00391886613317603!GO:0016197;endosome transport;0.00391886613317603!GO:0051540;metal cluster binding;0.00394009786278986!GO:0051536;iron-sulfur cluster binding;0.00394009786278986!GO:0006405;RNA export from nucleus;0.00394596018029337!GO:0048500;signal recognition particle;0.00400191366624875!GO:0043065;positive regulation of apoptosis;0.00405885194998145!GO:0005758;mitochondrial intermembrane space;0.00408948115313182!GO:0051052;regulation of DNA metabolic process;0.00412141804944098!GO:0030133;transport vesicle;0.00452811530589387!GO:0030134;ER to Golgi transport vesicle;0.00475337027548867!GO:0008180;signalosome;0.00475337027548867!GO:0008092;cytoskeletal protein binding;0.00475337027548867!GO:0065009;regulation of a molecular function;0.00480675405505144!GO:0043596;nuclear replication fork;0.00480675405505144!GO:0005876;spindle microtubule;0.0048756740560835!GO:0006144;purine base metabolic process;0.00491003823127789!GO:0006595;polyamine metabolic process;0.00495998474608697!GO:0030660;Golgi-associated vesicle membrane;0.00515186853171725!GO:0043068;positive regulation of programmed cell death;0.00544902452498577!GO:0003746;translation elongation factor activity;0.00550732508187414!GO:0007017;microtubule-based process;0.00552678059067393!GO:0008361;regulation of cell size;0.00558654383886092!GO:0006611;protein export from nucleus;0.0056338442860507!GO:0006509;membrane protein ectodomain proteolysis;0.005660888471398!GO:0033619;membrane protein proteolysis;0.005660888471398!GO:0031072;heat shock protein binding;0.00570748403066153!GO:0015992;proton transport;0.00570793578507698!GO:0043488;regulation of mRNA stability;0.00577196974004665!GO:0043487;regulation of RNA stability;0.00577196974004665!GO:0046467;membrane lipid biosynthetic process;0.00603563280577905!GO:0006818;hydrogen transport;0.00615741953264377!GO:0030131;clathrin adaptor complex;0.00646616090827615!GO:0048468;cell development;0.00646688238090777!GO:0016251;general RNA polymerase II transcription factor activity;0.00646688238090777!GO:0051087;chaperone binding;0.00646688238090777!GO:0017166;vinculin binding;0.00650734187463764!GO:0043492;ATPase activity, coupled to movement of substances;0.0065185372819861!GO:0000339;RNA cap binding;0.00653086997485824!GO:0000323;lytic vacuole;0.00653086997485824!GO:0005764;lysosome;0.00653086997485824!GO:0005741;mitochondrial outer membrane;0.00664328374926893!GO:0015631;tubulin binding;0.00673141459159513!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00684972268356225!GO:0000428;DNA-directed RNA polymerase complex;0.00684972268356225!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00693308192403764!GO:0005853;eukaryotic translation elongation factor 1 complex;0.00709610838289296!GO:0046489;phosphoinositide biosynthetic process;0.00718489079941605!GO:0046474;glycerophospholipid biosynthetic process;0.00723868945821213!GO:0030521;androgen receptor signaling pathway;0.00728366384232922!GO:0008312;7S RNA binding;0.00733396141313624!GO:0006284;base-excision repair;0.00751998448477092!GO:0043624;cellular protein complex disassembly;0.00763484163603643!GO:0032508;DNA duplex unwinding;0.00764660230415322!GO:0032392;DNA geometric change;0.00764660230415322!GO:0016741;transferase activity, transferring one-carbon groups;0.00769352485677734!GO:0043022;ribosome binding;0.00781483062271772!GO:0031970;organelle envelope lumen;0.00790870708349113!GO:0016301;kinase activity;0.00796492912173934!GO:0007346;regulation of progression through mitotic cell cycle;0.00809536789266315!GO:0006289;nucleotide-excision repair;0.0081429225598625!GO:0016049;cell growth;0.00818271277019926!GO:0005637;nuclear inner membrane;0.00851632921591125!GO:0005832;chaperonin-containing T-complex;0.00916348943357515!GO:0008168;methyltransferase activity;0.00916348943357515!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00920206494701248!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.009755724614638!GO:0045047;protein targeting to ER;0.009755724614638!GO:0030125;clathrin vesicle coat;0.0100778999113168!GO:0030665;clathrin coated vesicle membrane;0.0100778999113168!GO:0030127;COPII vesicle coat;0.0103528928098007!GO:0012507;ER to Golgi transport vesicle membrane;0.0103528928098007!GO:0004527;exonuclease activity;0.0106761621504593!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0107138905678586!GO:0051539;4 iron, 4 sulfur cluster binding;0.011187939564917!GO:0009451;RNA modification;0.011433838393232!GO:0007264;small GTPase mediated signal transduction;0.0117686915487762!GO:0016126;sterol biosynthetic process;0.0120337391176277!GO:0030833;regulation of actin filament polymerization;0.0120509829781557!GO:0046483;heterocycle metabolic process;0.0123562894993331!GO:0006520;amino acid metabolic process;0.0123698509912188!GO:0031124;mRNA 3'-end processing;0.0125499675782284!GO:0006950;response to stress;0.0126469693600315!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0131217520996111!GO:0043130;ubiquitin binding;0.0133846704311801!GO:0032182;small conjugating protein binding;0.0133846704311801!GO:0009112;nucleobase metabolic process;0.0135432379492723!GO:0007040;lysosome organization and biogenesis;0.0136427330659206!GO:0006007;glucose catabolic process;0.0136763688637124!GO:0000792;heterochromatin;0.0140342947748457!GO:0008047;enzyme activator activity;0.0144155079550082!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0144774710328059!GO:0015002;heme-copper terminal oxidase activity;0.0144774710328059!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0144774710328059!GO:0004129;cytochrome-c oxidase activity;0.0144774710328059!GO:0050681;androgen receptor binding;0.0148071089359194!GO:0030176;integral to endoplasmic reticulum membrane;0.0149358101875495!GO:0004003;ATP-dependent DNA helicase activity;0.0151047516746549!GO:0009116;nucleoside metabolic process;0.0151171858606436!GO:0004518;nuclease activity;0.0153616243647087!GO:0007033;vacuole organization and biogenesis;0.0154821683616952!GO:0046519;sphingoid metabolic process;0.0156708388077437!GO:0005862;muscle thin filament tropomyosin;0.0157605840890886!GO:0006740;NADPH regeneration;0.0158947840128294!GO:0006098;pentose-phosphate shunt;0.0158947840128294!GO:0006695;cholesterol biosynthetic process;0.0161370773278128!GO:0008538;proteasome activator activity;0.0162468927516325!GO:0006268;DNA unwinding during replication;0.0164558381049955!GO:0006497;protein amino acid lipidation;0.0164576597265829!GO:0000096;sulfur amino acid metabolic process;0.0165071884214171!GO:0051348;negative regulation of transferase activity;0.0166042244156858!GO:0032200;telomere organization and biogenesis;0.0166334241978092!GO:0000723;telomere maintenance;0.0166334241978092!GO:0008610;lipid biosynthetic process;0.0167725700363351!GO:0042393;histone binding;0.0174936188473127!GO:0005869;dynactin complex;0.0175840188813367!GO:0000922;spindle pole;0.0177763549324364!GO:0005669;transcription factor TFIID complex;0.0178158340499886!GO:0001836;release of cytochrome c from mitochondria;0.018019315011451!GO:0008234;cysteine-type peptidase activity;0.018144216243511!GO:0033673;negative regulation of kinase activity;0.0184279358786341!GO:0006469;negative regulation of protein kinase activity;0.0184279358786341!GO:0032984;macromolecular complex disassembly;0.0191616949992856!GO:0006672;ceramide metabolic process;0.0191826285916348!GO:0050662;coenzyme binding;0.0192520873621641!GO:0000228;nuclear chromosome;0.0202090139409692!GO:0043241;protein complex disassembly;0.0207331633842411!GO:0042770;DNA damage response, signal transduction;0.0211795828435221!GO:0043601;nuclear replisome;0.0213150990742555!GO:0030894;replisome;0.0213150990742555!GO:0004177;aminopeptidase activity;0.0214140654273274!GO:0000819;sister chromatid segregation;0.0218000954550019!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0219771313563372!GO:0001558;regulation of cell growth;0.0219838881678078!GO:0000209;protein polyubiquitination;0.0224019220443681!GO:0022415;viral reproductive process;0.0224683881772755!GO:0045045;secretory pathway;0.0225385013994027!GO:0030384;phosphoinositide metabolic process;0.0225855370521646!GO:0065007;biological regulation;0.0233645017387243!GO:0006778;porphyrin metabolic process;0.0233908831126244!GO:0033013;tetrapyrrole metabolic process;0.0233908831126244!GO:0046966;thyroid hormone receptor binding;0.0233908831126244!GO:0000070;mitotic sister chromatid segregation;0.0234350773356847!GO:0006650;glycerophospholipid metabolic process;0.0234350773356847!GO:0006897;endocytosis;0.0235430354715409!GO:0010324;membrane invagination;0.0235430354715409!GO:0006378;mRNA polyadenylation;0.0245236213699359!GO:0008287;protein serine/threonine phosphatase complex;0.0247243286704401!GO:0006376;mRNA splice site selection;0.0248983520195774!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0248983520195774!GO:0046822;regulation of nucleocytoplasmic transport;0.0253490859962442!GO:0051101;regulation of DNA binding;0.0253966795645115!GO:0030027;lamellipodium;0.0255452980374849!GO:0031625;ubiquitin protein ligase binding;0.0257693077485772!GO:0030031;cell projection biogenesis;0.0267074823975023!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0267461802254496!GO:0000086;G2/M transition of mitotic cell cycle;0.0268559018532325!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0269574207556866!GO:0016860;intramolecular oxidoreductase activity;0.0269574207556866!GO:0006220;pyrimidine nucleotide metabolic process;0.0277791029729704!GO:0000781;chromosome, telomeric region;0.0292891259463018!GO:0022890;inorganic cation transmembrane transporter activity;0.0294531874353972!GO:0000287;magnesium ion binding;0.0297699941622013!GO:0007021;tubulin folding;0.0301572048518549!GO:0035035;histone acetyltransferase binding;0.0303100164337615!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0303767544951291!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0305835610410519!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0308584773897423!GO:0005096;GTPase activator activity;0.0308921209501596!GO:0030518;steroid hormone receptor signaling pathway;0.0310415234023337!GO:0022406;membrane docking;0.0311987146381094!GO:0048278;vesicle docking;0.0311987146381094!GO:0031529;ruffle organization and biogenesis;0.0312395787180464!GO:0031570;DNA integrity checkpoint;0.0314435473202323!GO:0007004;telomere maintenance via telomerase;0.0315160817694625!GO:0003702;RNA polymerase II transcription factor activity;0.0320699354658805!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0320724441328659!GO:0006368;RNA elongation from RNA polymerase II promoter;0.032635485802867!GO:0048144;fibroblast proliferation;0.0327358720908517!GO:0048145;regulation of fibroblast proliferation;0.0327358720908517!GO:0006417;regulation of translation;0.0327724594576261!GO:0006892;post-Golgi vesicle-mediated transport;0.0331792344787334!GO:0005784;translocon complex;0.0331876536915633!GO:0030865;cortical cytoskeleton organization and biogenesis;0.033203443057874!GO:0043154;negative regulation of caspase activity;0.033203443057874!GO:0044262;cellular carbohydrate metabolic process;0.0348370512466335!GO:0009124;nucleoside monophosphate biosynthetic process;0.0349601772639538!GO:0009123;nucleoside monophosphate metabolic process;0.0349601772639538!GO:0045941;positive regulation of transcription;0.0349601772639538!GO:0019206;nucleoside kinase activity;0.0349664364089907!GO:0030496;midbody;0.0355246165148858!GO:0043189;H4/H2A histone acetyltransferase complex;0.0358427873090732!GO:0008601;protein phosphatase type 2A regulator activity;0.0365310356683443!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0372275373770123!GO:0009303;rRNA transcription;0.0373158602038737!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0373743650141032!GO:0051098;regulation of binding;0.0374668796351812!GO:0000910;cytokinesis;0.0375525709777045!GO:0030100;regulation of endocytosis;0.0376023474327918!GO:0035267;NuA4 histone acetyltransferase complex;0.0376196454233762!GO:0048146;positive regulation of fibroblast proliferation;0.0376261938676773!GO:0006904;vesicle docking during exocytosis;0.0380287030726559!GO:0044454;nuclear chromosome part;0.0391814405279677!GO:0042026;protein refolding;0.0394105237670062!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0397158724062328!GO:0010257;NADH dehydrogenase complex assembly;0.0397158724062328!GO:0033108;mitochondrial respiratory chain complex assembly;0.0397158724062328!GO:0045334;clathrin-coated endocytic vesicle;0.040279086749627!GO:0031123;RNA 3'-end processing;0.040443978086493!GO:0042168;heme metabolic process;0.040443978086493!GO:0016584;nucleosome positioning;0.0411262027313138!GO:0008320;protein transmembrane transporter activity;0.041596660387046!GO:0008017;microtubule binding;0.042344372600278!GO:0006275;regulation of DNA replication;0.042737615746729!GO:0042158;lipoprotein biosynthetic process;0.042737615746729!GO:0031902;late endosome membrane;0.0433467455202681!GO:0030503;regulation of cell redox homeostasis;0.0442210700777263!GO:0051059;NF-kappaB binding;0.0444303371199529!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0446151962708154!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0446151962708154!GO:0006400;tRNA modification;0.0448378700591164!GO:0006360;transcription from RNA polymerase I promoter;0.0449286604015092!GO:0006270;DNA replication initiation;0.0451255391901996!GO:0043414;biopolymer methylation;0.0454750422457716!GO:0008537;proteasome activator complex;0.0455891559168282!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0455891559168282!GO:0031371;ubiquitin conjugating enzyme complex;0.0455891559168282!GO:0000159;protein phosphatase type 2A complex;0.0458686283567807!GO:0032259;methylation;0.0458965981994245!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0466130962365565!GO:0016408;C-acyltransferase activity;0.0466595636673745!GO:0043433;negative regulation of transcription factor activity;0.0466595636673745!GO:0007034;vacuolar transport;0.0469250764456701!GO:0006506;GPI anchor biosynthetic process;0.0470776809079255!GO:0022884;macromolecule transmembrane transporter activity;0.0473738343557493!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0473738343557493!GO:0030911;TPR domain binding;0.0481113526261409!GO:0006917;induction of apoptosis;0.0482855474389711!GO:0008426;protein kinase C inhibitor activity;0.0487436241293416!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0491189260659225!GO:0045039;protein import into mitochondrial inner membrane;0.0491189260659225!GO:0008408;3'-5' exonuclease activity;0.0491229901250106!GO:0000725;recombinational repair;0.0494441655561627!GO:0000724;double-strand break repair via homologous recombination;0.0494441655561627!GO:0045792;negative regulation of cell size;0.0499937540663099 | |||
|sample_id=10846 | |sample_id=10846 | ||
|sample_note= | |sample_note= | ||
| Line 76: | Line 99: | ||
|sample_tissue=mesothelium | |sample_tissue=mesothelium | ||
|top_motifs=HSF1,2:1.98985094511;HOX{A5,B5}:1.86301108775;NKX3-1:1.72532960881;POU1F1:1.5634109366;AIRE:1.11593287869;ZNF384:1.09646882909;TOPORS:0.98712004631;TEAD1:0.930150283314;RXR{A,B,G}:0.921556097051;PAX4:0.904754811987;E2F1..5:0.888853556314;ZBTB16:0.87873673075;TFDP1:0.877905667106;TP53:0.857101168466;GZF1:0.831530214999;CDX1,2,4:0.816581627864;LMO2:0.813805410269;HOXA9_MEIS1:0.784189114117;bHLH_family:0.748638788974;FOXQ1:0.670976383005;NR1H4:0.659939706942;PAX5:0.62843463512;NR6A1:0.607112855618;PITX1..3:0.584802579015;XCPE1{core}:0.526615995012;STAT5{A,B}:0.523928359146;ELK1,4_GABP{A,B1}:0.498116882626;EN1,2:0.491165749357;UFEwm:0.486648308947;FOX{I1,J2}:0.455197294122;GATA4:0.428072408307;KLF4:0.422346020955;ARID5B:0.403220862089;ZBTB6:0.399200275106;MYB:0.397199693571;TFAP2B:0.343780482105;NFE2:0.328594414955;ZNF143:0.322677056269;OCT4_SOX2{dimer}:0.315979413926;GFI1B:0.314581842483;ONECUT1,2:0.267718707207;NKX3-2:0.262290097146;BACH2:0.255238151473;IKZF1:0.241820887267;HOX{A4,D4}:0.240309646491;FOXM1:0.231014870145;SNAI1..3:0.225239570423;NFE2L1:0.224633727783;NKX2-1,4:0.215785082043;FOS_FOS{B,L1}_JUN{B,D}:0.212671377514;CRX:0.206844171095;NR3C1:0.202632945497;LHX3,4:0.201917485823;MYOD1:0.196187432079;ZEB1:0.147737251712;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.13688114224;HES1:0.1360248995;VSX1,2:0.130935229838;TLX1..3_NFIC{dimer}:0.126703529579;GCM1,2:0.113107157289;TFCP2:0.112376193441;RXRA_VDR{dimer}:0.111265089742;SMAD1..7,9:0.100763531377;ZNF148:0.0925732231848;MZF1:0.0897095829374;PAX6:0.0845605238137;FOXP1:0.0843432925273;NFY{A,B,C}:0.0783535795646;DMAP1_NCOR{1,2}_SMARC:0.0674817860279;MAZ:0.0537702833388;EVI1:0.0535039107492;STAT2,4,6:0.0494702345764;TBX4,5:0.0393299798451;PBX1:0.0376059447238;BREu{core}:0.0331841226395;GFI1:0.0310241278484;EP300:0.0305683588119;GTF2I:0.0276117169462;HNF4A_NR2F1,2:0.0224278455946;FOXL1:0.020587385802;HLF:0.0180823504388;HMGA1,2:0.0130743891147;YY1:-0.0101354805754;MTE{core}:-0.0145364321702;TEF:-0.0283373457074;POU3F1..4:-0.0500878708872;ZIC1..3:-0.0591417378896;ESR1:-0.0688408996482;CDC5L:-0.0722637040142;CEBPA,B_DDIT3:-0.103823179116;STAT1,3:-0.107198912841;NANOG:-0.107998875869;NFKB1_REL_RELA:-0.10852197711;FOSL2:-0.109726306347;NKX2-2,8:-0.113187046824;ELF1,2,4:-0.133343807204;HNF1A:-0.135796543542;TBP:-0.149192975746;ALX1:-0.151513844351;IRF1,2:-0.16604302843;PPARG:-0.200300880994;POU5F1:-0.210382748103;SRF:-0.21683586415;MTF1:-0.216937586158;FOXP3:-0.220105507024;PRRX1,2:-0.22237917332;PAX3,7:-0.222444022553;PAX1,9:-0.225997580493;NR5A1,2:-0.233806409574;NRF1:-0.242803172116;POU2F1..3:-0.243248028859;SOX17:-0.247088990896;RREB1:-0.258153270078;EGR1..3:-0.287099983238;HIC1:-0.289382955507;AHR_ARNT_ARNT2:-0.290685517873;XBP1:-0.295378697725;GLI1..3:-0.295614166202;IRF7:-0.306760676537;HAND1,2:-0.34759620883;SOX2:-0.367098439698;ESRRA:-0.375514665399;NFIL3:-0.376097355461;GTF2A1,2:-0.38209590717;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.382379926245;RFX1:-0.389346929023;NFE2L2:-0.394149901749;ZNF423:-0.398581005753;RBPJ:-0.40459176142;NFATC1..3:-0.411305343448;SP1:-0.411318361227;IKZF2:-0.417641845891;ALX4:-0.420849030908;ADNP_IRX_SIX_ZHX:-0.424928980746;PAX8:-0.427477707091;GATA6:-0.432113542534;PAX2:-0.447338831011;POU6F1:-0.460410384553;CUX2:-0.468146075367;LEF1_TCF7_TCF7L1,2:-0.471877884508;HOX{A6,A7,B6,B7}:-0.47799339577;ETS1,2:-0.488597266604;SPZ1:-0.489316196687;SPI1:-0.505726998029;REST:-0.506558928554;SPIB:-0.512422628535;ZFP161:-0.521396272885;MAFB:-0.523281363319;T:-0.532536400985;TFAP2{A,C}:-0.544131628452;NFIX:-0.547535731638;FOXD3:-0.55958998832;MED-1{core}:-0.593246514774;MYBL2:-0.601576684299;FOXA2:-0.612332368824;NANOG{mouse}:-0.615409630078;EBF1:-0.617778403804;TLX2:-0.630991241507;PRDM1:-0.631252814517;AR:-0.641952704908;ATF4:-0.645637978656;RUNX1..3:-0.64933170972;FOXO1,3,4:-0.651467642624;SOX{8,9,10}:-0.674296649861;ATF5_CREB3:-0.674769159141;TGIF1:-0.703259804933;MEF2{A,B,C,D}:-0.747252485223;FOXN1:-0.781031201463;ZNF238:-0.802881192984;MYFfamily:-0.836687430526;NKX6-1,2:-0.865223131415;FOX{F1,F2,J1}:-0.883175513315;NHLH1,2:-0.887927555701;PATZ1:-0.903287793373;RFX2..5_RFXANK_RFXAP:-0.910073650016;SREBF1,2:-0.913529159682;HBP1_HMGB_SSRP1_UBTF:-0.936012952927;HIF1A:-0.95501725877;CREB1:-0.959516514954;ATF2:-0.96402632259;TAL1_TCF{3,4,12}:-1.05322721773;JUN:-1.07909975109;NKX2-3_NKX2-5:-1.0980856529;FOX{D1,D2}:-1.10106411326;DBP:-1.10877390694;ATF6:-1.2292900185;SOX5:-1.23396829998;RORA:-1.26165873044;HMX1:-1.39489631736;TFAP4:-1.51074680751;PDX1:-1.55333853689;BPTF:-2.04666776785 | |top_motifs=HSF1,2:1.98985094511;HOX{A5,B5}:1.86301108775;NKX3-1:1.72532960881;POU1F1:1.5634109366;AIRE:1.11593287869;ZNF384:1.09646882909;TOPORS:0.98712004631;TEAD1:0.930150283314;RXR{A,B,G}:0.921556097051;PAX4:0.904754811987;E2F1..5:0.888853556314;ZBTB16:0.87873673075;TFDP1:0.877905667106;TP53:0.857101168466;GZF1:0.831530214999;CDX1,2,4:0.816581627864;LMO2:0.813805410269;HOXA9_MEIS1:0.784189114117;bHLH_family:0.748638788974;FOXQ1:0.670976383005;NR1H4:0.659939706942;PAX5:0.62843463512;NR6A1:0.607112855618;PITX1..3:0.584802579015;XCPE1{core}:0.526615995012;STAT5{A,B}:0.523928359146;ELK1,4_GABP{A,B1}:0.498116882626;EN1,2:0.491165749357;UFEwm:0.486648308947;FOX{I1,J2}:0.455197294122;GATA4:0.428072408307;KLF4:0.422346020955;ARID5B:0.403220862089;ZBTB6:0.399200275106;MYB:0.397199693571;TFAP2B:0.343780482105;NFE2:0.328594414955;ZNF143:0.322677056269;OCT4_SOX2{dimer}:0.315979413926;GFI1B:0.314581842483;ONECUT1,2:0.267718707207;NKX3-2:0.262290097146;BACH2:0.255238151473;IKZF1:0.241820887267;HOX{A4,D4}:0.240309646491;FOXM1:0.231014870145;SNAI1..3:0.225239570423;NFE2L1:0.224633727783;NKX2-1,4:0.215785082043;FOS_FOS{B,L1}_JUN{B,D}:0.212671377514;CRX:0.206844171095;NR3C1:0.202632945497;LHX3,4:0.201917485823;MYOD1:0.196187432079;ZEB1:0.147737251712;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.13688114224;HES1:0.1360248995;VSX1,2:0.130935229838;TLX1..3_NFIC{dimer}:0.126703529579;GCM1,2:0.113107157289;TFCP2:0.112376193441;RXRA_VDR{dimer}:0.111265089742;SMAD1..7,9:0.100763531377;ZNF148:0.0925732231848;MZF1:0.0897095829374;PAX6:0.0845605238137;FOXP1:0.0843432925273;NFY{A,B,C}:0.0783535795646;DMAP1_NCOR{1,2}_SMARC:0.0674817860279;MAZ:0.0537702833388;EVI1:0.0535039107492;STAT2,4,6:0.0494702345764;TBX4,5:0.0393299798451;PBX1:0.0376059447238;BREu{core}:0.0331841226395;GFI1:0.0310241278484;EP300:0.0305683588119;GTF2I:0.0276117169462;HNF4A_NR2F1,2:0.0224278455946;FOXL1:0.020587385802;HLF:0.0180823504388;HMGA1,2:0.0130743891147;YY1:-0.0101354805754;MTE{core}:-0.0145364321702;TEF:-0.0283373457074;POU3F1..4:-0.0500878708872;ZIC1..3:-0.0591417378896;ESR1:-0.0688408996482;CDC5L:-0.0722637040142;CEBPA,B_DDIT3:-0.103823179116;STAT1,3:-0.107198912841;NANOG:-0.107998875869;NFKB1_REL_RELA:-0.10852197711;FOSL2:-0.109726306347;NKX2-2,8:-0.113187046824;ELF1,2,4:-0.133343807204;HNF1A:-0.135796543542;TBP:-0.149192975746;ALX1:-0.151513844351;IRF1,2:-0.16604302843;PPARG:-0.200300880994;POU5F1:-0.210382748103;SRF:-0.21683586415;MTF1:-0.216937586158;FOXP3:-0.220105507024;PRRX1,2:-0.22237917332;PAX3,7:-0.222444022553;PAX1,9:-0.225997580493;NR5A1,2:-0.233806409574;NRF1:-0.242803172116;POU2F1..3:-0.243248028859;SOX17:-0.247088990896;RREB1:-0.258153270078;EGR1..3:-0.287099983238;HIC1:-0.289382955507;AHR_ARNT_ARNT2:-0.290685517873;XBP1:-0.295378697725;GLI1..3:-0.295614166202;IRF7:-0.306760676537;HAND1,2:-0.34759620883;SOX2:-0.367098439698;ESRRA:-0.375514665399;NFIL3:-0.376097355461;GTF2A1,2:-0.38209590717;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.382379926245;RFX1:-0.389346929023;NFE2L2:-0.394149901749;ZNF423:-0.398581005753;RBPJ:-0.40459176142;NFATC1..3:-0.411305343448;SP1:-0.411318361227;IKZF2:-0.417641845891;ALX4:-0.420849030908;ADNP_IRX_SIX_ZHX:-0.424928980746;PAX8:-0.427477707091;GATA6:-0.432113542534;PAX2:-0.447338831011;POU6F1:-0.460410384553;CUX2:-0.468146075367;LEF1_TCF7_TCF7L1,2:-0.471877884508;HOX{A6,A7,B6,B7}:-0.47799339577;ETS1,2:-0.488597266604;SPZ1:-0.489316196687;SPI1:-0.505726998029;REST:-0.506558928554;SPIB:-0.512422628535;ZFP161:-0.521396272885;MAFB:-0.523281363319;T:-0.532536400985;TFAP2{A,C}:-0.544131628452;NFIX:-0.547535731638;FOXD3:-0.55958998832;MED-1{core}:-0.593246514774;MYBL2:-0.601576684299;FOXA2:-0.612332368824;NANOG{mouse}:-0.615409630078;EBF1:-0.617778403804;TLX2:-0.630991241507;PRDM1:-0.631252814517;AR:-0.641952704908;ATF4:-0.645637978656;RUNX1..3:-0.64933170972;FOXO1,3,4:-0.651467642624;SOX{8,9,10}:-0.674296649861;ATF5_CREB3:-0.674769159141;TGIF1:-0.703259804933;MEF2{A,B,C,D}:-0.747252485223;FOXN1:-0.781031201463;ZNF238:-0.802881192984;MYFfamily:-0.836687430526;NKX6-1,2:-0.865223131415;FOX{F1,F2,J1}:-0.883175513315;NHLH1,2:-0.887927555701;PATZ1:-0.903287793373;RFX2..5_RFXANK_RFXAP:-0.910073650016;SREBF1,2:-0.913529159682;HBP1_HMGB_SSRP1_UBTF:-0.936012952927;HIF1A:-0.95501725877;CREB1:-0.959516514954;ATF2:-0.96402632259;TAL1_TCF{3,4,12}:-1.05322721773;JUN:-1.07909975109;NKX2-3_NKX2-5:-1.0980856529;FOX{D1,D2}:-1.10106411326;DBP:-1.10877390694;ATF6:-1.2292900185;SOX5:-1.23396829998;RORA:-1.26165873044;HMX1:-1.39489631736;TFAP4:-1.51074680751;PDX1:-1.55333853689;BPTF:-2.04666776785 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10846-111E9;search_select_hide=table117:FF:10846-111E9 | |||
}} | }} | ||
Latest revision as of 15:09, 3 June 2020
| Name: | mesothelioma cell line:NCI-H226 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs13062 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13062
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13062
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.568 |
| 10 | 10 | 0.541 |
| 100 | 100 | 0.065 |
| 101 | 101 | 0.778 |
| 102 | 102 | 0.803 |
| 103 | 103 | 0.163 |
| 104 | 104 | 0.909 |
| 105 | 105 | 0.364 |
| 106 | 106 | 0.176 |
| 107 | 107 | 0.12 |
| 108 | 108 | 0.893 |
| 109 | 109 | 0.0358 |
| 11 | 11 | 0.516 |
| 110 | 110 | 0.047 |
| 111 | 111 | 0.778 |
| 112 | 112 | 0.783 |
| 113 | 113 | 0.0108 |
| 114 | 114 | 0.248 |
| 115 | 115 | 0.864 |
| 116 | 116 | 0.0989 |
| 117 | 117 | 0.257 |
| 118 | 118 | 0.227 |
| 119 | 119 | 0.821 |
| 12 | 12 | 0.813 |
| 120 | 120 | 0.286 |
| 121 | 121 | 0.936 |
| 122 | 122 | 0.593 |
| 123 | 123 | 0.94 |
| 124 | 124 | 0.0932 |
| 125 | 125 | 0.823 |
| 126 | 126 | 0.962 |
| 127 | 127 | 0.937 |
| 128 | 128 | 0.789 |
| 129 | 129 | 0.734 |
| 13 | 13 | 0.0191 |
| 130 | 130 | 0.968 |
| 131 | 131 | 0.88 |
| 132 | 132 | 0.584 |
| 133 | 133 | 0.0822 |
| 134 | 134 | 0.0857 |
| 135 | 135 | 0.00346 |
| 136 | 136 | 0.0135 |
| 137 | 137 | 0.0772 |
| 138 | 138 | 0.737 |
| 139 | 139 | 0.144 |
| 14 | 14 | 0.352 |
| 140 | 140 | 0.297 |
| 141 | 141 | 0.492 |
| 142 | 142 | 0.614 |
| 143 | 143 | 0.205 |
| 144 | 144 | 0.902 |
| 145 | 145 | 0.729 |
| 146 | 146 | 0.426 |
| 147 | 147 | 0.735 |
| 148 | 148 | 0.641 |
| 149 | 149 | 0.346 |
| 15 | 15 | 0.943 |
| 150 | 150 | 0.0999 |
| 151 | 151 | 0.944 |
| 152 | 152 | 0.0333 |
| 153 | 153 | 0.258 |
| 154 | 154 | 0.831 |
| 155 | 155 | 0.715 |
| 156 | 156 | 0.858 |
| 157 | 157 | 0.379 |
| 158 | 158 | 0.0128 |
| 159 | 159 | 0.467 |
| 16 | 16 | 0.283 |
| 160 | 160 | 0.227 |
| 161 | 161 | 0.154 |
| 162 | 162 | 0.577 |
| 163 | 163 | 0.945 |
| 164 | 164 | 0.0591 |
| 165 | 165 | 0.286 |
| 166 | 166 | 0.82 |
| 167 | 167 | 0.936 |
| 168 | 168 | 0.313 |
| 169 | 169 | 0.0224 |
| 17 | 17 | 0.959 |
| 18 | 18 | 0.904 |
| 19 | 19 | 0.855 |
| 2 | 2 | 0.889 |
| 20 | 20 | 0.244 |
| 21 | 21 | 0.00383 |
| 22 | 22 | 0.819 |
| 23 | 23 | 0.0361 |
| 24 | 24 | 0.187 |
| 25 | 25 | 0.345 |
| 26 | 26 | 0.481 |
| 27 | 27 | 0.9 |
| 28 | 28 | 0.157 |
| 29 | 29 | 0.26 |
| 3 | 3 | 0.655 |
| 30 | 30 | 0.552 |
| 31 | 31 | 0.497 |
| 32 | 32 | 0.389 |
| 33 | 33 | 0.459 |
| 34 | 34 | 0.746 |
| 35 | 35 | 0.705 |
| 36 | 36 | 0.667 |
| 37 | 37 | 0.17 |
| 38 | 38 | 0.841 |
| 39 | 39 | 0.349 |
| 4 | 4 | 0.535 |
| 40 | 40 | 0.515 |
| 41 | 41 | 0.0091 |
| 42 | 42 | 0.666 |
| 43 | 43 | 0.0924 |
| 44 | 44 | 0.48 |
| 45 | 45 | 0.975 |
| 46 | 46 | 0.83 |
| 47 | 47 | 0.489 |
| 48 | 48 | 0.224 |
| 49 | 49 | 0.16 |
| 5 | 5 | 0.0832 |
| 50 | 50 | 0.467 |
| 51 | 51 | 0.518 |
| 52 | 52 | 0.596 |
| 53 | 53 | 0.882 |
| 54 | 54 | 0.399 |
| 55 | 55 | 0.614 |
| 56 | 56 | 0.476 |
| 57 | 57 | 0.0838 |
| 58 | 58 | 0.287 |
| 59 | 59 | 0.488 |
| 6 | 6 | 0.833 |
| 60 | 60 | 0.991 |
| 61 | 61 | 0.443 |
| 62 | 62 | 0.37 |
| 63 | 63 | 0.279 |
| 64 | 64 | 0.804 |
| 65 | 65 | 0.553 |
| 66 | 66 | 0.0306 |
| 67 | 67 | 0.717 |
| 68 | 68 | 0.849 |
| 69 | 69 | 0.109 |
| 7 | 7 | 0.793 |
| 70 | 70 | 0.951 |
| 71 | 71 | 0.0901 |
| 72 | 72 | 0.202 |
| 73 | 73 | 0.143 |
| 74 | 74 | 0.834 |
| 75 | 75 | 0.526 |
| 76 | 76 | 0.174 |
| 77 | 77 | 0.0555 |
| 78 | 78 | 0.154 |
| 79 | 79 | 0.568 |
| 8 | 8 | 0.249 |
| 80 | 80 | 0.0786 |
| 81 | 81 | 0.375 |
| 82 | 82 | 0.717 |
| 83 | 83 | 0.759 |
| 84 | 84 | 0.986 |
| 85 | 85 | 0.0459 |
| 86 | 86 | 0.583 |
| 87 | 87 | 0.0108 |
| 88 | 88 | 0.268 |
| 89 | 89 | 0.275 |
| 9 | 9 | 0.225 |
| 90 | 90 | 0.227 |
| 91 | 91 | 0.187 |
| 92 | 92 | 0.0489 |
| 93 | 93 | 0.697 |
| 94 | 94 | 0.494 |
| 95 | 95 | 0.132 |
| 96 | 96 | 0.583 |
| 97 | 97 | 0.823 |
| 98 | 98 | 0.653 |
| 99 | 99 | 0.379 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13062
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102424 mesothelioma cell line sample
FF:0103008 NCI-H226 cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000076 (squamous epithelial cell)
0000213 (lining cell)
0000215 (barrier cell)
0000082 (epithelial cell of lung)
0000255 (eukaryotic cell)
0000077 (mesothelial cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
0050615 (respiratory system cancer)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
1324 (lung cancer)
305 (carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002048 (lung)
0002100 (trunk)
0000483 (epithelium)
0000479 (tissue)
0000064 (organ part)
0004119 (endoderm-derived structure)
0000466 (immaterial anatomical entity)
0000062 (organ)
0004111 (anatomical conduit)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000063 (organ segment)
0004802 (respiratory tract epithelium)
0000025 (tube)
0005911 (endo-epithelium)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000119 (cell layer)
0009569 (subdivision of trunk)
0005178 (thoracic cavity element)
0000072 (segment of respiratory tract)
0005177 (trunk region element)
0004807 (respiratory system epithelium)
0000117 (respiratory tube)
0000171 (respiration organ)
0000115 (lung epithelium)
0000464 (anatomical space)
0005181 (thoracic segment organ)
0010317 (germ layer / neural crest derived structure)
0000065 (respiratory tract)
0000170 (pair of lungs)
0001004 (respiratory system)
0002224 (thoracic cavity)
0000915 (thoracic segment of trunk)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0100353 (lung cell line sample)
0101120 (epithelial cell line sample)
0100762 (lung cancer cell line sample)
0102553 (non-small cell lung cancer cell line sample)
0102424 (mesothelioma cell line sample)
0103008 (NCI-H226 cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000222 (mesodermal cell)
UBERON:0001041 (foregut)
UBERON:0008947 (respiratory primordium)
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0010316 (germ layer / neural crest)
