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MCL coexpression mm9:978

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Phase1 CAGE Peaks

 Short description
Mm9::chr19:44368563..44368589,+p1@Scd2
Mm9::chr19:44369392..44369409,+p@chr19:44369392..44369409
+
Mm9::chr19:44369444..44369462,-p@chr19:44369444..44369462
-
Mm9::chr19:44369456..44369470,+p@chr19:44369456..44369470
+
Mm9::chr19:44369487..44369508,+p@chr19:44369487..44369508
+
Mm9::chr19:44377691..44377708,+p1@Mir5114
Mm9::chr19:44377837..44377902,+p@chr19:44377837..44377902
+
Mm9::chr19:44378303..44378323,+p@chr19:44378303..44378323
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004768stearoyl-CoA 9-desaturase activity0.00936832301539474
GO:0016717oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water0.00936832301539474
GO:0006633fatty acid biosynthetic process0.0303950035610585
GO:0046394carboxylic acid biosynthetic process0.0303950035610585
GO:0016053organic acid biosynthetic process0.0303950035610585
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen0.0433718658120127
GO:0006631fatty acid metabolic process0.0475851327766081



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
nervous system1.35e-2375
central nervous system4.27e-2373
ectoderm-derived structure4.06e-2095
ectoderm4.06e-2095
presumptive ectoderm4.06e-2095
regional part of nervous system3.24e-1854
neurectoderm2.19e-1764
neural plate2.19e-1764
presumptive neural plate2.19e-1764
neural tube8.08e-1752
neural rod8.08e-1752
future spinal cord8.08e-1752
neural keel8.08e-1752
structure with developmental contribution from neural crest8.97e-1492
brain1.00e-1347
future brain1.00e-1347
ecto-epithelium1.57e-1373
regional part of brain2.68e-1346
gray matter3.36e-1334
pre-chordal neural plate2.24e-1149
anterior neural tube1.28e-1040
brain grey matter2.55e-1029
regional part of telencephalon2.55e-1029
telencephalon2.55e-1029
regional part of forebrain3.37e-1039
forebrain3.37e-1039
future forebrain3.37e-1039
posterior neural tube1.50e-0712
chordal neural plate1.50e-0712
cerebral cortex2.48e-0721
cerebral hemisphere2.48e-0721
pallium2.48e-0721


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.016751
MA0004.10.434673
MA0006.10.747445
MA0007.10.419994
MA0009.10.870101
MA0014.10.162935
MA0017.10.804572
MA0019.11.64517
MA0024.10.826339
MA0025.11.10341
MA0027.12.51754
MA0028.11.40661
MA0029.10.804619
MA0030.10.811181
MA0031.10.775627
MA0038.11.41387
MA0040.10.882616
MA0041.10.360875
MA0042.10.348174
MA0043.10.966833
MA0046.10.906029
MA0048.10.335404
MA0050.10.472794
MA0051.10.586414
MA0052.10.890676
MA0055.10.282934
MA0056.10
MA0057.10.31126
MA0058.10.341628
MA0059.10.931383
MA0060.11.08928
MA0061.10.224905
MA0063.10
MA0066.10.566617
MA0067.11.21448
MA0068.11.09399
MA0069.10.891016
MA0070.10.881319
MA0071.11.18945
MA0072.10.872842
MA0073.10.0216016
MA0074.13.33073
MA0076.10.845594
MA0077.10.851175
MA0078.10.61926
MA0081.10.375851
MA0083.10.96604
MA0084.11.54225
MA0087.10.922929
MA0088.10.229377
MA0089.10
MA0090.10.401197
MA0091.11.98602
MA0092.11.03695
MA0093.10.289361
MA0095.10
MA0098.10
MA0100.10.519598
MA0101.10.362124
MA0103.10.307078
MA0105.10.823589
MA0106.10.626997
MA0107.10.301222
MA0108.20.710846
MA0109.10
MA0111.10.415012
MA0113.10.598933
MA0114.10.633896
MA0115.10.969632
MA0116.10.27152
MA0117.10.937363
MA0119.10.951747
MA0122.10.957212
MA0124.11.16127
MA0125.11.0872
MA0130.10
MA0131.10.683521
MA0132.10
MA0133.10
MA0135.11.00325
MA0136.10.550755
MA0139.12.9589
MA0140.10.519484
MA0141.10.325895
MA0142.10.761136
MA0143.10.615203
MA0144.10.225588
MA0145.10.0701568
MA0146.10.198184
MA0147.11.24068
MA0148.10.450593
MA0149.10.367458
MA0062.20.426733
MA0035.20.524137
MA0039.20.144815
MA0138.20.675599
MA0002.20.172399
MA0137.20.32312
MA0104.21.03907
MA0047.20.576767
MA0112.20.0701537
MA0065.20.0704227
MA0150.10.419883
MA0151.10
MA0152.10.576873
MA0153.11.01988
MA0154.10.100744
MA0155.10.0804339
MA0156.10.314185
MA0157.10.729116
MA0158.10
MA0159.10.246253
MA0160.10.453546
MA0161.10
MA0162.10.230918
MA0163.10.408151
MA0164.10.551114
MA0080.20.302064
MA0018.20.560731
MA0099.20.669311
MA0079.20.174131
MA0102.21.59466
MA0258.10.210437
MA0259.10.227035
MA0442.10