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Coexpression cluster:C4851

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Full id: C4851_Osteoblast_occipital_skeletal_Adipocyte_Mesenchymal_leiomyoma_Smooth



Phase1 CAGE Peaks

Hg19::chrX:134166948..134166995,+p4@FAM127A
Hg19::chrX:134167069..134167118,+p3@FAM127A
Hg19::chrX:134167308..134167338,+p@chrX:134167308..134167338
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
multi-cellular organism5.33e-21656
cell layer2.04e-18309
epithelium2.37e-18306
anatomical cluster4.23e-16373
multi-tissue structure1.60e-15342
anatomical conduit1.68e-15240
anatomical system4.56e-15624
anatomical group1.06e-14625
epithelial vesicle1.81e-1478
dense mesenchyme tissue3.30e-1473
multilaminar epithelium5.03e-1483
paraxial mesoderm9.26e-1472
presumptive paraxial mesoderm9.26e-1472
mesenchyme1.31e-13160
entire embryonic mesenchyme1.31e-13160
somite1.81e-1371
presomitic mesoderm1.81e-1371
presumptive segmental plate1.81e-1371
dermomyotome1.81e-1371
trunk paraxial mesoderm1.81e-1371
trunk mesenchyme7.69e-13122
embryo7.85e-13592
embryonic structure1.07e-12564
developing anatomical structure1.31e-12581
muscle tissue1.69e-1264
musculature1.69e-1264
musculature of body1.69e-1264
germ layer1.74e-12560
germ layer / neural crest1.74e-12560
embryonic tissue1.74e-12560
presumptive structure1.74e-12560
germ layer / neural crest derived structure1.74e-12560
epiblast (generic)1.74e-12560
skeletal muscle tissue2.13e-1262
striated muscle tissue2.13e-1262
myotome2.13e-1262
tube4.04e-12192
splanchnic layer of lateral plate mesoderm2.17e-1183
vasculature6.16e-1078
vascular system6.16e-1078
organism subdivision9.70e-10264
epithelial tube open at both ends1.64e-0959
blood vessel1.64e-0959
blood vasculature1.64e-0959
vascular cord1.64e-0959
trunk3.31e-09199
structure with developmental contribution from neural crest3.84e-09132
vessel4.35e-0968
artery4.56e-0942
arterial blood vessel4.56e-0942
arterial system4.56e-0942
unilaminar epithelium6.43e-09148
epithelial tube7.83e-09117
central nervous system5.24e-0881
adult organism6.30e-08114
organ part1.59e-07218
systemic artery2.65e-0733
systemic arterial system2.65e-0733
ectoderm-derived structure3.10e-07171
ectoderm3.10e-07171
presumptive ectoderm3.10e-07171
circulatory system5.25e-07112


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.