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Coexpression cluster:C2426

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Full id: C2426_pons_merkel_Saos2_Dendritic_locus_medulla_parietal



Phase1 CAGE Peaks

  Short description
Hg19::chr17:61116852..61116863,+ p4@AB074278
Hg19::chr17:61116864..61116883,+ p3@AB074278
Hg19::chr17:61116885..61116914,+ p1@AB074278
Hg19::chr17:61116919..61116955,+ p2@AB074278


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
plasmacytoid dendritic cell2.35e-073
Uber Anatomy
Ontology termp-valuen
neural tube2.13e-5356
neural rod2.13e-5356
future spinal cord2.13e-5356
neural keel2.13e-5356
central nervous system4.58e-5081
regional part of nervous system5.84e-4853
regional part of brain5.84e-4853
brain4.20e-4768
future brain4.20e-4768
nervous system1.24e-4589
regional part of forebrain1.70e-4141
forebrain1.70e-4141
anterior neural tube1.70e-4141
future forebrain1.70e-4141
neural plate8.51e-3882
presumptive neural plate8.51e-3882
neurectoderm3.41e-3786
brain grey matter3.67e-3634
gray matter3.67e-3634
telencephalon5.23e-3634
adult organism4.38e-33114
cerebral hemisphere1.05e-3232
regional part of telencephalon1.76e-3232
pre-chordal neural plate3.33e-3061
ecto-epithelium3.53e-30104
regional part of cerebral cortex3.64e-2522
neocortex5.33e-2520
structure with developmental contribution from neural crest7.16e-24132
ectoderm-derived structure9.08e-24171
ectoderm9.08e-24171
presumptive ectoderm9.08e-24171
cerebral cortex1.30e-2125
pallium1.30e-2125
neural nucleus3.98e-179
nucleus of brain3.98e-179
organ system subdivision1.40e-16223
brainstem1.69e-136
telencephalic nucleus3.27e-137
basal ganglion5.20e-139
nuclear complex of neuraxis5.20e-139
aggregate regional part of brain5.20e-139
collection of basal ganglia5.20e-139
cerebral subcortex5.20e-139
gyrus8.64e-136
posterior neural tube1.05e-1215
chordal neural plate1.05e-1215
tube2.40e-11192
segmental subdivision of nervous system2.59e-0913
corpus striatum2.87e-084
striatum2.87e-084
ventral part of telencephalon2.87e-084
future corpus striatum2.87e-084
segmental subdivision of hindbrain5.71e-0812
hindbrain5.71e-0812
presumptive hindbrain5.71e-0812
pons1.16e-073
anatomical conduit1.26e-07240
medulla oblongata1.69e-073
myelencephalon1.69e-073
future myelencephalon1.69e-073
spinal cord2.16e-073
dorsal region element2.16e-073
dorsum2.16e-073
occipital lobe3.25e-075
parietal lobe3.46e-075
frontal cortex3.99e-073
temporal lobe4.99e-076
diencephalon7.10e-077
future diencephalon7.10e-077


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0214529
MA0004.10.71247
MA0006.10.532262
MA0007.10.6918
MA0009.11.20602
MA0014.10.0695829
MA0017.10.577281
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.14.0617
MA0051.13.18613
MA0052.11.12718
MA0055.11.8712
MA0056.10
MA0057.10.248209
MA0058.10.605914
MA0059.10.604454
MA0060.10.393285
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.313194
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.10.00636811
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.12.13662
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.10.182167
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.12.72365
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.10.521546
MA0105.10.232357
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.12.05499
MA0114.10.447443
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.13.11837
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.11.70272
MA0146.10.221129
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.20.0247757
MA0138.20.928035
MA0002.20.98779
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.20.187982
MA0065.20.199162
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.10.229241
MA0155.10.180766
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.10.0928415
MA0163.10.0725493
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.20.000248021
MA0102.21.75932
MA0258.10.418966
MA0259.11.1888
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
MYC#460945.22228187160940.001344309395272740.0088736145198388
YY1#752844.911170749853860.00171871838055440.0106807823959729



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.