Personal tools

Coexpression cluster:C3428

From FANTOM5_SSTAR

Revision as of 19:10, 8 August 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Full id: C3428_cerebellum_medial_hippocampus_amygdala_occipital_brain_olfactory



Phase1 CAGE Peaks

Hg19::chr14:51491727..51491730,-p@chr14:51491727..51491730
-
Hg19::chr20:10256173..10256180,+p7@SNAP25
Hg19::chr20:44688143..44688157,+p@chr20:44688143..44688157
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube4.25e-8757
neural rod4.25e-8757
future spinal cord4.25e-8757
neural keel4.25e-8757
central nervous system6.75e-7382
regional part of brain1.09e-7259
brain1.06e-6869
future brain1.06e-6869
regional part of nervous system1.94e-6894
nervous system1.94e-6894
regional part of forebrain3.47e-6841
forebrain3.47e-6841
future forebrain3.47e-6841
anterior neural tube2.44e-6642
neural plate2.62e-6686
presumptive neural plate2.62e-6686
telencephalon1.59e-6534
gray matter3.15e-6534
brain grey matter3.15e-6534
regional part of telencephalon3.43e-6333
neurectoderm9.99e-6390
cerebral hemisphere1.22e-6132
pre-chordal neural plate2.05e-5061
cerebral cortex4.90e-4625
pallium4.90e-4625
regional part of cerebral cortex2.55e-4422
adult organism2.79e-41115
neocortex1.12e-3920
head3.32e-38123
anterior region of body8.57e-36129
craniocervical region8.57e-36129
ectoderm-derived structure4.14e-33169
ectoderm5.34e-32173
presumptive ectoderm5.34e-32173
basal ganglion3.80e-219
nuclear complex of neuraxis3.80e-219
aggregate regional part of brain3.80e-219
collection of basal ganglia3.80e-219
cerebral subcortex3.80e-219
posterior neural tube9.36e-2115
chordal neural plate9.36e-2115
nucleus of brain2.57e-209
neural nucleus2.57e-209
tube2.42e-18194
telencephalic nucleus1.97e-167
gyrus8.22e-166
temporal lobe2.96e-157
segmental subdivision of hindbrain7.63e-1512
hindbrain7.63e-1512
presumptive hindbrain7.63e-1512
anatomical conduit8.39e-14241
segmental subdivision of nervous system1.49e-1313
limbic system3.38e-135
brainstem5.41e-138
parietal lobe6.25e-135
epithelium3.40e-12309
organ part5.65e-12219
cell layer6.14e-12312
anatomical cluster1.34e-11286
organism subdivision1.24e-10365
corpus striatum1.30e-104
striatum1.30e-104
ventral part of telencephalon1.30e-104
future corpus striatum1.30e-104
regional part of metencephalon1.16e-099
metencephalon1.16e-099
future metencephalon1.16e-099
middle temporal gyrus9.44e-093
caudate-putamen1.90e-083
dorsal striatum1.90e-083
occipital lobe2.40e-085
spinal cord6.06e-083
pons1.09e-073
brainstem nucleus2.50e-073
medulla oblongata3.20e-073
myelencephalon3.20e-073
future myelencephalon3.20e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.