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Coexpression cluster:C1803

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Full id: C1803_heart_melanoma_nonsmall_left_Fibroblast_substantia_Melanocyte



Phase1 CAGE Peaks

Hg19::chr18:64271316..64271334,-p1@CDH19
Hg19::chr18:64271339..64271357,-p3@CDH19
Hg19::chr18:64271363..64271390,-p2@CDH19
Hg19::chr18:64271391..64271398,-p5@CDH19
Hg19::chr18:64271403..64271414,-p4@CDH19


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism2.73e-83115
neural tube6.86e-4057
neural rod6.86e-4057
future spinal cord6.86e-4057
neural keel6.86e-4057
central nervous system2.50e-3482
neurectoderm1.15e-3390
neural plate1.55e-3286
presumptive neural plate1.55e-3286
regional part of nervous system2.44e-3294
nervous system2.44e-3294
regional part of brain4.57e-3259
brain1.99e-3169
future brain1.99e-3169
anterior neural tube5.30e-3142
regional part of forebrain2.13e-3041
forebrain2.13e-3041
future forebrain2.13e-3041
gray matter3.94e-2434
brain grey matter3.94e-2434
telencephalon1.00e-2334
regional part of telencephalon6.75e-2333
cerebral hemisphere1.37e-2132
tube2.89e-21194
pre-chordal neural plate3.53e-2161
ectoderm3.34e-20173
presumptive ectoderm3.34e-20173
anatomical conduit1.04e-19241
anterior region of body1.69e-19129
craniocervical region1.69e-19129
ectoderm-derived structure3.76e-19169
head6.66e-19123
regional part of cerebral cortex7.21e-1822
neocortex6.15e-1620
anatomical cluster2.36e-15286
cerebral cortex5.67e-1525
pallium5.67e-1525
multi-tissue structure1.79e-14347
primary circulatory organ6.89e-1427
epithelium2.26e-13309
organ3.25e-13511
cell layer5.73e-13312
nucleus of brain2.83e-119
neural nucleus2.83e-119
heart4.08e-1124
primitive heart tube4.08e-1124
primary heart field4.08e-1124
anterior lateral plate mesoderm4.08e-1124
heart tube4.08e-1124
heart primordium4.08e-1124
cardiac mesoderm4.08e-1124
cardiogenic plate4.08e-1124
heart rudiment4.08e-1124
basal ganglion1.02e-109
nuclear complex of neuraxis1.02e-109
aggregate regional part of brain1.02e-109
collection of basal ganglia1.02e-109
cerebral subcortex1.02e-109
embryo1.66e-10612
organism subdivision1.68e-10365
posterior neural tube6.96e-1015
chordal neural plate6.96e-1015
multi-cellular organism7.24e-10659
embryonic structure9.73e-10605
developing anatomical structure9.73e-10605
brainstem1.02e-098
germ layer2.25e-09604
embryonic tissue2.25e-09604
presumptive structure2.25e-09604
epiblast (generic)2.25e-09604
telencephalic nucleus5.72e-097
compound organ8.26e-0969
diencephalon3.03e-087
future diencephalon3.03e-087
anatomical system4.66e-08625
anatomical group5.58e-08626
segmental subdivision of nervous system6.06e-0813
gyrus2.86e-076
segmental subdivision of hindbrain6.25e-0712
hindbrain6.25e-0712
presumptive hindbrain6.25e-0712
temporal lobe8.28e-077


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.