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Coexpression cluster:C2389

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Full id: C2389_caudate_parietal_small_smallcell_occipital_merkel_medial



Phase1 CAGE Peaks

Hg19::chr16:7353211..7353229,+p@chr16:7353211..7353229
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Hg19::chr16:7354219..7354246,+p@chr16:7354219..7354246
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Hg19::chr16:7354337..7354363,+p@chr16:7354337..7354363
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Hg19::chr16:7355031..7355049,+p@chr16:7355031..7355049
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube2.75e-8957
neural rod2.75e-8957
future spinal cord2.75e-8957
neural keel2.75e-8957
regional part of brain5.19e-7559
central nervous system8.48e-7382
regional part of forebrain3.57e-7041
forebrain3.57e-7041
future forebrain3.57e-7041
brain4.58e-7069
future brain4.58e-7069
anterior neural tube3.02e-6842
regional part of nervous system4.82e-6894
nervous system4.82e-6894
neural plate1.57e-6186
presumptive neural plate1.57e-6186
telencephalon3.38e-6134
gray matter3.67e-6134
brain grey matter3.67e-6134
regional part of telencephalon4.58e-5933
neurectoderm4.29e-5890
cerebral hemisphere6.46e-5832
adult organism4.29e-50115
pre-chordal neural plate4.63e-4661
cerebral cortex4.53e-4425
pallium4.53e-4425
anterior region of body5.06e-40129
craniocervical region5.06e-40129
regional part of cerebral cortex1.53e-3922
head1.84e-39123
ectoderm-derived structure2.47e-36169
neocortex1.02e-3520
ectoderm4.30e-35173
presumptive ectoderm4.30e-35173
posterior neural tube5.16e-2115
chordal neural plate5.16e-2115
tube1.31e-19194
basal ganglion2.99e-189
nuclear complex of neuraxis2.99e-189
aggregate regional part of brain2.99e-189
collection of basal ganglia2.99e-189
cerebral subcortex2.99e-189
nucleus of brain3.39e-189
neural nucleus3.39e-189
segmental subdivision of hindbrain1.49e-1512
hindbrain1.49e-1512
presumptive hindbrain1.49e-1512
anatomical conduit4.49e-15241
epithelium5.71e-15309
cell layer1.17e-14312
telencephalic nucleus1.58e-147
segmental subdivision of nervous system3.53e-1413
gyrus4.14e-146
temporal lobe3.76e-137
organism subdivision4.07e-13365
anatomical cluster3.29e-12286
occipital lobe4.65e-125
brainstem6.42e-128
limbic system3.12e-115
organ part6.92e-11219
regional part of metencephalon1.55e-109
metencephalon1.55e-109
future metencephalon1.55e-109
diencephalon3.00e-107
future diencephalon3.00e-107
corpus striatum1.90e-094
striatum1.90e-094
ventral part of telencephalon1.90e-094
future corpus striatum1.90e-094
multi-tissue structure4.33e-08347
parietal lobe5.21e-085
middle temporal gyrus7.09e-083
caudate-putamen2.20e-073
dorsal striatum2.20e-073
spinal cord2.56e-073
pons4.52e-073
medulla oblongata6.56e-073
myelencephalon6.56e-073
future myelencephalon6.56e-073
brainstem nucleus8.56e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.