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Coexpression cluster:C1391

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Full id: C1391_anaplastic_thalamus_Astrocyte_caudate_amygdala_medulla_locus



Phase1 CAGE Peaks

Hg19::chr14:33474041..33474050,+p@chr14:33474041..33474050
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Hg19::chr14:33546996..33546998,+p@chr14:33546996..33546998
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Hg19::chr14:33548838..33548841,+p@chr14:33548838..33548841
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Hg19::chr14:33611419..33611424,+p@chr14:33611419..33611424
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Hg19::chr14:33652663..33652666,+p@chr14:33652663..33652666
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Hg19::chr14:34236821..34236823,+p@chr14:34236821..34236823
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube7.01e-6456
neural rod7.01e-6456
future spinal cord7.01e-6456
neural keel7.01e-6456
regional part of nervous system4.65e-5953
regional part of brain4.65e-5953
central nervous system7.10e-5881
nervous system3.33e-5689
regional part of forebrain4.13e-5641
forebrain4.13e-5641
anterior neural tube4.13e-5641
future forebrain4.13e-5641
brain1.68e-5468
future brain1.68e-5468
neurectoderm2.24e-5386
brain grey matter4.35e-5334
gray matter4.35e-5334
neural plate6.63e-5382
presumptive neural plate6.63e-5382
telencephalon1.49e-5234
regional part of telencephalon8.10e-5032
cerebral hemisphere1.76e-4932
adult organism2.92e-44114
pre-chordal neural plate6.21e-4361
ecto-epithelium7.11e-41104
cerebral cortex5.95e-3925
pallium5.95e-3925
ectoderm-derived structure2.36e-35171
ectoderm2.36e-35171
presumptive ectoderm2.36e-35171
structure with developmental contribution from neural crest4.27e-34132
regional part of cerebral cortex6.09e-3422
neocortex7.36e-3120
organ system subdivision4.29e-27223
anatomical cluster3.89e-17373
neural nucleus2.62e-159
nucleus of brain2.62e-159
basal ganglion3.40e-159
nuclear complex of neuraxis3.40e-159
aggregate regional part of brain3.40e-159
collection of basal ganglia3.40e-159
cerebral subcortex3.40e-159
organ part1.40e-13218
telencephalic nucleus3.57e-127
multi-tissue structure8.38e-12342
temporal lobe3.46e-116
tube5.73e-11192
brainstem1.98e-106
anatomical conduit2.74e-10240
epithelium3.83e-10306
posterior neural tube5.68e-1015
chordal neural plate5.68e-1015
gyrus6.01e-106
embryo6.83e-10592
cell layer7.39e-10309
developing anatomical structure1.25e-09581
embryonic structure1.91e-09564
organ2.37e-09503
germ layer3.26e-09560
germ layer / neural crest3.26e-09560
embryonic tissue3.26e-09560
presumptive structure3.26e-09560
germ layer / neural crest derived structure3.26e-09560
epiblast (generic)3.26e-09560
limbic system5.33e-095
occipital lobe8.35e-095
parietal lobe1.55e-085
segmental subdivision of nervous system1.93e-0713
corpus striatum2.07e-074
striatum2.07e-074
ventral part of telencephalon2.07e-074
future corpus striatum2.07e-074
multi-cellular organism3.70e-07656
anatomical system8.77e-07624
anatomical group1.00e-06625


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.