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Coexpression cluster:C3340

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Full id: C3340_occipital_temporal_brain_hippocampus_cerebellum_substantia_parietal



Phase1 CAGE Peaks

Hg19::chr12:86578513..86578516,-p@chr12:86578513..86578516
-
Hg19::chr6:124231666..124231669,+p@chr6:124231666..124231669
+
Hg19::chr9:8339833..8339834,-p@chr9:8339833..8339834
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube2.88e-8056
neural rod2.88e-8056
future spinal cord2.88e-8056
neural keel2.88e-8056
regional part of nervous system3.67e-7553
regional part of brain3.67e-7553
central nervous system5.31e-6381
neural plate6.06e-6382
presumptive neural plate6.06e-6382
brain3.77e-6068
future brain3.77e-6068
neurectoderm1.18e-5986
nervous system1.82e-5989
brain grey matter3.21e-5134
gray matter3.21e-5134
telencephalon5.06e-5134
regional part of forebrain2.48e-5041
forebrain2.48e-5041
anterior neural tube2.48e-5041
future forebrain2.48e-5041
ecto-epithelium5.94e-48104
regional part of telencephalon8.88e-4532
cerebral hemisphere1.55e-4432
adult organism3.46e-43114
structure with developmental contribution from neural crest1.29e-40132
pre-chordal neural plate2.78e-3861
regional part of cerebral cortex8.58e-3722
cerebral cortex3.92e-3225
pallium3.92e-3225
posterior neural tube5.55e-3115
chordal neural plate5.55e-3115
ectoderm-derived structure8.95e-31171
ectoderm8.95e-31171
presumptive ectoderm8.95e-31171
segmental subdivision of nervous system4.37e-3013
neocortex5.31e-3020
segmental subdivision of hindbrain2.62e-2612
hindbrain2.62e-2612
presumptive hindbrain2.62e-2612
organ system subdivision6.05e-26223
brainstem8.71e-246
tube4.69e-22192
neural nucleus2.90e-219
nucleus of brain2.90e-219
organ part4.51e-17218
gyrus9.78e-176
regional part of metencephalon3.33e-169
metencephalon3.33e-169
future metencephalon3.33e-169
anatomical conduit5.97e-16240
basal ganglion6.32e-169
nuclear complex of neuraxis6.32e-169
aggregate regional part of brain6.32e-169
collection of basal ganglia6.32e-169
cerebral subcortex6.32e-169
anatomical cluster1.45e-15373
telencephalic nucleus2.33e-147
limbic system1.28e-135
epithelium1.95e-13306
cell layer3.22e-13309
multi-tissue structure7.58e-13342
pons8.69e-133
medulla oblongata9.43e-133
myelencephalon9.43e-133
future myelencephalon9.43e-133
Ammon's horn1.05e-092
lobe parts of cerebral cortex1.05e-092
hippocampal formation1.05e-092
limbic lobe1.05e-092
dorsal plus ventral thalamus1.14e-092
thalamic complex1.14e-092
temporal lobe1.88e-096
corpus striatum2.14e-094
striatum2.14e-094
ventral part of telencephalon2.14e-094
future corpus striatum2.14e-094
multi cell component structure2.75e-092
neuron projection bundle2.75e-092
middle temporal gyrus3.83e-092
locus ceruleus3.83e-092
brainstem nucleus3.83e-092
hindbrain nucleus3.83e-092
occipital lobe2.30e-085
parietal lobe7.03e-085
cerebellum5.40e-076
rhombic lip5.40e-076
organ5.73e-07503
embryo9.07e-07592


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.