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Coexpression cluster:C1391

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Full id: C1391_anaplastic_thalamus_Astrocyte_caudate_amygdala_medulla_locus



Phase1 CAGE Peaks

Hg19::chr14:33474041..33474050,+p@chr14:33474041..33474050
+
Hg19::chr14:33546996..33546998,+p@chr14:33546996..33546998
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Hg19::chr14:33548838..33548841,+p@chr14:33548838..33548841
+
Hg19::chr14:33611419..33611424,+p@chr14:33611419..33611424
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Hg19::chr14:33652663..33652666,+p@chr14:33652663..33652666
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Hg19::chr14:34236821..34236823,+p@chr14:34236821..34236823
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube7.01e-6456
neural rod7.01e-6456
future spinal cord7.01e-6456
neural keel7.01e-6456
regional part of nervous system4.65e-5953
regional part of brain4.65e-5953
central nervous system7.10e-5881
nervous system3.33e-5689
regional part of forebrain4.13e-5641
forebrain4.13e-5641
anterior neural tube4.13e-5641
future forebrain4.13e-5641
brain1.68e-5468
future brain1.68e-5468
neurectoderm2.24e-5386
brain grey matter4.35e-5334
gray matter4.35e-5334
neural plate6.63e-5382
presumptive neural plate6.63e-5382
telencephalon1.49e-5234
regional part of telencephalon8.10e-5032
cerebral hemisphere1.76e-4932
adult organism2.92e-44114
pre-chordal neural plate6.21e-4361
ecto-epithelium7.11e-41104
cerebral cortex5.95e-3925
pallium5.95e-3925
ectoderm-derived structure2.36e-35171
ectoderm2.36e-35171
presumptive ectoderm2.36e-35171
structure with developmental contribution from neural crest4.27e-34132
regional part of cerebral cortex6.09e-3422
neocortex7.36e-3120
organ system subdivision4.29e-27223
anatomical cluster3.89e-17373
neural nucleus2.62e-159
nucleus of brain2.62e-159
basal ganglion3.40e-159
nuclear complex of neuraxis3.40e-159
aggregate regional part of brain3.40e-159
collection of basal ganglia3.40e-159
cerebral subcortex3.40e-159
organ part1.40e-13218
telencephalic nucleus3.57e-127
multi-tissue structure8.38e-12342
temporal lobe3.46e-116
tube5.73e-11192
brainstem1.98e-106
anatomical conduit2.74e-10240
epithelium3.83e-10306
posterior neural tube5.68e-1015
chordal neural plate5.68e-1015
gyrus6.01e-106
embryo6.83e-10592
cell layer7.39e-10309
developing anatomical structure1.25e-09581
embryonic structure1.91e-09564
organ2.37e-09503
germ layer3.26e-09560
germ layer / neural crest3.26e-09560
embryonic tissue3.26e-09560
presumptive structure3.26e-09560
germ layer / neural crest derived structure3.26e-09560
epiblast (generic)3.26e-09560
limbic system5.33e-095
occipital lobe8.35e-095
parietal lobe1.55e-085
segmental subdivision of nervous system1.93e-0713
corpus striatum2.07e-074
striatum2.07e-074
ventral part of telencephalon2.07e-074
future corpus striatum2.07e-074
multi-cellular organism3.70e-07656
anatomical system8.77e-07624
anatomical group1.00e-06625


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.026277
MA0004.10.558729
MA0006.10.391183
MA0007.10.539222
MA0009.11.03681
MA0014.10.0254709
MA0017.10.432438
MA0019.10.7124
MA0024.10.929647
MA0025.11.17262
MA0027.12.65688
MA0028.10.408079
MA0029.10.949428
MA0030.10.937696
MA0031.10.871496
MA0038.10.665566
MA0040.10.955415
MA0041.10.578072
MA0042.11.3446
MA0043.11.03713
MA0046.11.02569
MA0048.10.152639
MA0050.10.545671
MA0051.10.661179
MA0052.10.959373
MA0055.10.0586456
MA0056.10
MA0057.10.147053
MA0058.10.458909
MA0059.10.457555
MA0060.10.267412
MA0061.10.23892
MA0063.10
MA0066.10.66601
MA0067.11.35893
MA0068.10.199491
MA0069.11.02175
MA0070.11.01032
MA0071.10.625297
MA0072.11.00572
MA0073.10.00076337
MA0074.10.660398
MA0076.10.475586
MA0077.10.997832
MA0078.10.763954
MA0081.10.457725
MA0083.11.04447
MA0084.11.5477
MA0087.11.00322
MA0088.10.0971959
MA0089.10
MA0090.10.490736
MA0091.10.561458
MA0092.10.522012
MA0093.10.394379
MA0095.10
MA0098.10
MA0100.10.679972
MA0101.10.397846
MA0103.10.381434
MA0105.10.134725
MA0106.10.70837
MA0107.10.320267
MA0108.20.868347
MA0109.10
MA0111.10.504913
MA0113.10.725375
MA0114.10.314898
MA0115.11.28169
MA0116.10.323925
MA0117.11.07516
MA0119.10.440684
MA0122.11.10154
MA0124.11.23968
MA0125.11.15445
MA0130.10
MA0131.10.782708
MA0132.10
MA0133.10
MA0135.11.06778
MA0136.10.672893
MA0139.10.226048
MA0140.10.622527
MA0141.10.455728
MA0142.10.838805
MA0143.10.725558
MA0144.10.299851
MA0145.10.107156
MA0146.10.232472
MA0147.10.327615
MA0148.10.584698
MA0149.10.612449
MA0062.20.23336
MA0035.21.50688
MA0039.20.00570825
MA0138.20.765223
MA0002.20.255126
MA0137.20.414885
MA0104.20.26661
MA0047.20.695777
MA0112.20.101413
MA0065.20.109623
MA0150.10.484557
MA0151.10
MA0152.10.629368
MA0153.12.56485
MA0154.10.132326
MA0155.10.0961854
MA0156.10.417278
MA0157.10.810597
MA0158.10
MA0159.10.328286
MA0160.10.600559
MA0161.10
MA0162.10.0383129
MA0163.10.273773
MA0164.11.74929
MA0080.20.394469
MA0018.20.709805
MA0099.20.629739
MA0079.27.22997e-05
MA0102.21.58513
MA0258.10.289793
MA0259.10.336472
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.