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Coexpression cluster:C2731


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Full id: C2731_optic_Endothelial_small_corpus_Prostate_medulla_Pericytes

Phase1 CAGE Peaks


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
cell layer1.51e-34309
anatomical conduit5.17e-31240
anatomical cluster3.82e-27373
vascular system9.96e-2778
structure with developmental contribution from neural crest4.57e-25132
neural plate1.72e-2382
presumptive neural plate1.72e-2382
cardiovascular system1.44e-21109
circulatory system2.54e-21112
neural tube6.35e-2156
neural rod6.35e-2156
future spinal cord6.35e-2156
neural keel6.35e-2156
splanchnic layer of lateral plate mesoderm2.76e-1983
regional part of nervous system5.93e-1953
regional part of brain5.93e-1953
multi-tissue structure5.89e-18342
future brain2.86e-1768
epithelial tube open at both ends6.77e-1759
blood vessel6.77e-1759
blood vasculature6.77e-1759
vascular cord6.77e-1759
epithelial vesicle6.41e-1678
central nervous system7.65e-1681
adult organism2.75e-15114
pre-chordal neural plate2.81e-1561
dense mesenchyme tissue1.01e-1473
unilaminar epithelium1.12e-14148
paraxial mesoderm1.54e-1472
presumptive paraxial mesoderm1.54e-1472
epithelial tube2.88e-14117
presomitic mesoderm4.37e-1471
presumptive segmental plate4.37e-1471
trunk paraxial mesoderm4.37e-1471
nervous system5.33e-1489
anatomical system5.84e-14624
anatomical group8.62e-14625
regional part of forebrain3.77e-1341
anterior neural tube3.77e-1341
future forebrain3.77e-1341
muscle tissue2.11e-1264
musculature of body2.11e-1264
skeletal muscle tissue3.12e-1262
striated muscle tissue3.12e-1262
multi-cellular organism7.54e-12656
arterial blood vessel9.10e-1242
arterial system9.10e-1242
trunk mesenchyme1.65e-11122
multilaminar epithelium1.97e-1183
brain grey matter1.05e-1034
gray matter1.05e-1034
systemic artery1.95e-1033
systemic arterial system1.95e-1033
regional part of telencephalon1.37e-0932
cerebral hemisphere1.68e-0932
posterior neural tube1.84e-0915
chordal neural plate1.84e-0915
germ layer2.12e-09560
germ layer / neural crest2.12e-09560
embryonic tissue2.12e-09560
presumptive structure2.12e-09560
germ layer / neural crest derived structure2.12e-09560
epiblast (generic)2.12e-09560
blood vessel endothelium3.82e-0918
cardiovascular system endothelium3.82e-0918
embryonic structure7.44e-09564

Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs

JASPAR motifs



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.