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Coexpression cluster:C188: Difference between revisions

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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!6.81e-35!115;UBERON:0005743!5.19e-15!86;UBERON:0003075!7.65e-14!86;UBERON:0007284!7.65e-14!86;UBERON:0001017!9.86e-14!82;UBERON:0000468!1.50e-13!659;UBERON:0001049!1.68e-13!57;UBERON:0005068!1.68e-13!57;UBERON:0006241!1.68e-13!57;UBERON:0007135!1.68e-13!57;UBERON:0000073!3.70e-13!94;UBERON:0001016!3.70e-13!94;UBERON:0002346!1.90e-12!90;UBERON:0003080!8.43e-12!42;UBERON:0000475!1.16e-11!365;UBERON:0002780!2.44e-11!41;UBERON:0001890!2.44e-11!41;UBERON:0006240!2.44e-11!41;UBERON:0002616!3.65e-11!59;UBERON:0000955!9.98e-11!69;UBERON:0006238!9.98e-11!69;UBERON:0003056!5.66e-10!61;UBERON:0000467!9.16e-10!625;UBERON:0000480!1.64e-09!626;UBERON:0001893!3.41e-08!34;UBERON:0002020!3.47e-08!34;UBERON:0003528!3.47e-08!34;UBERON:0004121!3.55e-08!169;UBERON:0000481!6.23e-08!347;UBERON:0002791!7.49e-08!33;UBERON:0000922!7.85e-08!612;UBERON:0000033!1.25e-07!123;UBERON:0001869!1.48e-07!32;UBERON:0000924!1.54e-07!173;UBERON:0006601!1.54e-07!173;UBERON:0000153!1.58e-07!129;UBERON:0007811!1.58e-07!129;UBERON:0000483!3.51e-07!309;UBERON:0000119!3.67e-07!312
|ontology_enrichment_uberon=UBERON:0007023!6.81e-35!115;UBERON:0005743!5.19e-15!86;UBERON:0003075!7.65e-14!86;UBERON:0007284!7.65e-14!86;UBERON:0001017!9.86e-14!82;UBERON:0000468!1.50e-13!659;UBERON:0001049!1.68e-13!57;UBERON:0005068!1.68e-13!57;UBERON:0006241!1.68e-13!57;UBERON:0007135!1.68e-13!57;UBERON:0000073!3.70e-13!94;UBERON:0001016!3.70e-13!94;UBERON:0002346!1.90e-12!90;UBERON:0003080!8.43e-12!42;UBERON:0000475!1.16e-11!365;UBERON:0002780!2.44e-11!41;UBERON:0001890!2.44e-11!41;UBERON:0006240!2.44e-11!41;UBERON:0002616!3.65e-11!59;UBERON:0000955!9.98e-11!69;UBERON:0006238!9.98e-11!69;UBERON:0003056!5.66e-10!61;UBERON:0000467!9.16e-10!625;UBERON:0000480!1.64e-09!626;UBERON:0001893!3.41e-08!34;UBERON:0002020!3.47e-08!34;UBERON:0003528!3.47e-08!34;UBERON:0004121!3.55e-08!169;UBERON:0000481!6.23e-08!347;UBERON:0002791!7.49e-08!33;UBERON:0000922!7.85e-08!612;UBERON:0000033!1.25e-07!123;UBERON:0001869!1.48e-07!32;UBERON:0000924!1.54e-07!173;UBERON:0006601!1.54e-07!173;UBERON:0000153!1.58e-07!129;UBERON:0007811!1.58e-07!129;UBERON:0000483!3.51e-07!309;UBERON:0000119!3.67e-07!312
|tfbs_overrepresentation=0.510141,0.267679,0.028518,0.765534,0.0732242,0.311124,0.143841,0.0843517,0.259433,0.181385,0.163165,0.632137,0.0517422,0.0508125,0.344684,0.849783,0.0406432,0.196028,0.800288,0.852302,0.426015,0.923239,0.0445713,0.17773,0.716253,0.29734,0.0262252,0.772541,0.314922,0.332153,0.998891,0.695895,0.0175871,0.539377,0.334769,0.736114,1,0.0433875,0.731786,0.871005,0.0340092,0.522541,6.94536e-05,0.399022,0.0930884,0.665505,0.683308,0.146839,0.463358,0.18933,0.872268,0.230295,0.172492,0.0285212,0.217409,0.687186,0.00255846,0.711262,0.911047,0.0516263,0.222472,0.113435,0.443959,0.00289521,0.810758,0.00500085,0.226227,0.840532,0.499026,0.0231137,0.182204,0.614943,0.937117,0.0882565,0.199583,0.400837,0.0849637,0.0115102,0.675729,0.194218,0.348725,0.239253,0.369065,0.297228,0.00885639,0.930248,0.0502462,2.53126e-08,0.994157,0.853753,0.930043,0.778832,0.346916,0.763025,0.741735,0.876771,0.684799,0.0127836,0.0281538,0.0178019,0.524063,0.00218188,0.303765,0.103754,0.00156363,0.351694,0.338755,0.00090032,0.944638,0.453237,0.937203,0.641607,0.991818,0.41102,0.213353,0.638905,0.456431,0.82276,0.00216188,0.263501,0.179594,0.841996,0.29343,0.277267,0.829302,0.517682,0.00846635,0.357346,0.0176397,0.144224,0.838347,0.405964,0.100487,0.495308,0.00277844,0.440314,0.863244,0.815259,0.63092,0.006393,0.495153,0.00101559,0.0434666,0.389561,0.596914,0.8813,0.00135851,0.48415,0.69222,0.33614,6.70332e-05,0.00779442,0.000436567,0.550341,0.726069,0.314691,0.67033,1.87874e-05,0.210147,0.6386,0.00244235,0.346184,0.501541,0.000422251,0.984905,0.972684,0.123136,0.379338,0.70536,0.00116723,0.140238,0.279423,0.881099,0.808165,0.236344,0.152396,0.655326,0.0807387,0.23314,0.659191,0.88601,0.195787,0.561501,0.301908,0.896893,0.0866049,0.982607,0.343321,0.473087,0.210087,0.0551829,0.418185,0.545051,0.0920113,0.28333,0.760796,0.0120173,0.841921,0.157228,0.968136,0.302536,0.842479,0.605082,0.843499,0.809107,0.78482,0.00877348,0.539286,0.00475712,0.526323,0.16479,0.961981,0.0417188,0.47497,0.00119549,0.641561,0.169006,0.611003,0.304469,0.0059906,0.475671,4.77588e-05,0.000242624,0.0825767,0.397671,0.569671,0.455485,0.930532,0.116864,0.839964,0.528104,0.578461,0.7186,0.420096,0.0830658,0.554548,0.761941,0.300769,0.0199134,0.293862,0.00134975,0.88744,0.0914529,0.727462,0.306485,0.63451,0.717268,0.465984,0.161549,0.0811365,0.408416,6.1881e-06,0.000209598,0.809749,0.590732,0.00263757,0.434058,0.502992,0.630473,0.0723885,0.565214,0.00600971,0.16559,0.117726,0.647244,0.714362,0.110325,0.779807,0.975951,0.902649,0.919699,0.856255,0.507463,0.999552,0.503169,0.319495,0.125473,0.00147399,0.00221713,0.804726,0.000291606,0.000257545,1.18254e-05,0.999871,0.239118,0.484563,0.0413076,0.170469,0.164418,0.00455804,1.14397e-06,0.000619302,0.811926,0.0578175,0.0377741,2.32549e-05,0.000127969,0.0021187,0.0153433,0.0331696,0.00125507,0.0172453,0.0237099,0.000316268,0.000158694,0.0451857,0.0620056,0.000278963,0.853261,0.000938093,0.119303,0.171705,0.0230735,1.5445e-05,0.000158855,1.8136e-05,0.0563543,0.0108554,0.016394,0.00484793,0.0247896,9.41101e-08,0.00310167,0.0216606,2.71621e-06,0.00913494,0.0249276,0.104409,0.000578071,0.230932,3.33e-06,2.3095e-05,0.00409783,0.0988161,0.22162,3.00709e-07,0.319779,4.81753e-05,5.30498e-05,0.846393,0.0124893,0.95183,0.0523832,0.0349458,0.184532,0.162502,0.0188521,0.274597,6.71966e-07,0.046985,1.51503e-08,0.00243785,4.35573e-05,0.474225,0.000547937,0.000158937,0.608392,0.872416,0.190922,0.723068,0.000158167,0.0071372,0.0499198,0.0063762,8.30989e-06,2.8371e-06,1.35478e-10,0.240412,0.203234,2.11896e-06,1.8078e-08,0.745719,0.201657,0.650652,0.394298,0.119715,0.00254739,0.0356628,0.00240666,0.862498,0.317791,0.0884339,0.2218,0.628246,0.455178,1.26076e-07,0.501636,0.00356951,0.00121881,0.0709004,0.000598981,3.58328e-05,0.48961,0.00135106,3.18272e-06,1,1.49312e-06,0.0986317,2.13109e-06,0.775848,0.535555,0.237491,0.00122247,3.86925e-08,0.0626937,0.75703,0.443914,0.000928934,0.0315087,0.0921028,4.914e-05,0.0605735,0.00674064,1.86458e-05,0.0509684,0.519331,4.60528e-07,0.000222947,0.0102138,0.296076,1.03514e-06,1.72576e-07,0.63671,0.0262014,6.087e-05,0.0191762,0.00877218,0.0653005,0.379181,0.000392651,0.000140598,0.00284679,5.80541e-07,0.0264541,0.0634382,0.28121,0.30308,0.146449,0.754901,0.078966,0.118271,0.159854,0.00689009,0.744998,0.937326,0.838267,0.0177495,0.000479256,0.000302961,1.72553e-09,0.0117815,0.00436948,0.00457209,2.71918e-06,0.284201,0.0666534,0.36265,0.817265,0.109693,0.0970221,0.0335142,0.839883,0.0215706,8.6454e-06,0.0492746,0.925231,0.755086,0.00107001,0.000145595,0.733027,0.126579,0.0217105,0.262896,0.00762945,0.99574,0.0460479,0.999924,0.415007,0.994063,0.0011579,0.5016,0.412326,0.316101,0.29554,0.00208525,0.00807187,0.74959,0.0382757,0.652681,0.735708,0.109209,0.0189049,0.0574837,0.970519,0.000970208,5.7651e-08,0.196432,7.76619e-05,0.336232,0.041254,0.679111,2.89643e-05,0.101589,0.624653,0.247931,0.997978,0.182396,0.00139053,0.67876,0.223538,0.126667,0.00151586,0.190564,0.290572,0.179546,2.69319e-05,0.0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}}
}}

Revision as of 17:45, 8 August 2012


Full id: C188_left_heart_tongue_skeletal_Skeletal_diaphragm_throat



Phase1 CAGE Peaks

Hg19::chr10:127569398..127569410,-p5@DHX32
Hg19::chr10:77945410..77945435,+p@chr10:77945410..77945435
+
Hg19::chr10:92725775..92725780,+p@chr10:92725775..92725780
+
Hg19::chr12:114886372..114886399,-p@chr12:114886372..114886399
-
Hg19::chr12:114886422..114886429,-p@chr12:114886422..114886429
-
Hg19::chr12:3309741..3309748,+p@chr12:3309741..3309748
+
Hg19::chr12:56080980..56080982,+p@chr12:56080980..56080982
+
Hg19::chr12:70004523..70004545,-p3@LRRC10
Hg19::chr12:70004575..70004590,-p4@LRRC10
Hg19::chr12:94730118..94730123,-p13@CCDC41
Hg19::chr13:111935498..111935509,+p35@ARHGEF7
Hg19::chr13:24334287..24334315,-p@chr13:24334287..24334315
-
Hg19::chr14:104408818..104408833,-p2@ENST00000557640
Hg19::chr14:23852481..23852521,-p@chr14:23852481..23852521
-
Hg19::chr14:23856796..23856821,+p@chr14:23856796..23856821
+
Hg19::chr14:23862653..23862669,+p@chr14:23862653..23862669
+
Hg19::chr14:23862685..23862696,+p@chr14:23862685..23862696
+
Hg19::chr14:23862698..23862705,+p@chr14:23862698..23862705
+
Hg19::chr14:23862866..23862886,+p@chr14:23862866..23862886
+
Hg19::chr14:23862999..23863032,+p@chr14:23862999..23863032
+
Hg19::chr14:23863078..23863082,+p@chr14:23863078..23863082
+
Hg19::chr14:23863529..23863540,-p@chr14:23863529..23863540
-
Hg19::chr14:23866230..23866266,-p@chr14:23866230..23866266
-
Hg19::chr15:26640200..26640207,+p3@ENST00000451579
Hg19::chr15:26640223..26640233,+p2@ENST00000451579
Hg19::chr15:26640236..26640246,+p1@ENST00000451579
Hg19::chr15:26640258..26640266,+p4@ENST00000451579
Hg19::chr15:26640282..26640290,+p5@ENST00000451579
Hg19::chr15:35082732..35082764,-p@chr15:35082732..35082764
-
Hg19::chr15:44171970..44171983,-p@chr15:44171970..44171983
-
Hg19::chr15:65042595..65042606,-p@chr15:65042595..65042606
-
Hg19::chr15:65042618..65042632,-p@chr15:65042618..65042632
-
Hg19::chr15:77964112..77964131,-p@chr15:77964112..77964131
-
Hg19::chr15:77964143..77964150,-p@chr15:77964143..77964150
-
Hg19::chr15:83474864..83474869,-p4@FSD2
Hg19::chr17:45286706..45286723,+p1@MYL4
Hg19::chr17:4806374..4806394,-p1@CHRNE
Hg19::chr17:65440428..65440449,-p@chr17:65440428..65440449
-
Hg19::chr18:21906552..21906584,+p@chr18:21906552..21906584
+
Hg19::chr18:28807557..28807562,-p@chr18:28807557..28807562
-
Hg19::chr19:3933460..3933476,+p2@ITGB1BP3
Hg19::chr19:3933579..3933594,+p1@ITGB1BP3
Hg19::chr1:109849612..109849651,-p1@MYBPHL
Hg19::chr1:109849679..109849688,-p3@MYBPHL
Hg19::chr1:11905799..11905806,-p@chr1:11905799..11905806
-
Hg19::chr1:11905830..11905839,-p@chr1:11905830..11905839
-
Hg19::chr1:11905915..11905921,-p@chr1:11905915..11905921
-
Hg19::chr1:11906020..11906041,+p@chr1:11906020..11906041
+
Hg19::chr1:11906044..11906050,-p@chr1:11906044..11906050
-
Hg19::chr1:11907265..11907271,-p9@NPPA
Hg19::chr1:11907318..11907327,-p7@NPPA
Hg19::chr1:11907395..11907410,-p4@NPPA
Hg19::chr1:11907408..11907415,+p@chr1:11907408..11907415
+
Hg19::chr1:11907415..11907418,-p15@NPPA
Hg19::chr1:11907440..11907450,+p@chr1:11907440..11907450
+
Hg19::chr1:11907441..11907453,-p3@NPPA
Hg19::chr1:11907474..11907481,-p10@NPPA
Hg19::chr1:11907829..11907847,-p1@NPPA
Hg19::chr1:11907940..11907947,-p2@NPPA
Hg19::chr1:201342333..201342350,+p@chr1:201342333..201342350
+
Hg19::chr1:233842857..233842870,-p@chr1:233842857..233842870
-
Hg19::chr1:43676416..43676417,-p@chr1:43676416..43676417
-
Hg19::chr2:149639329..149639360,-p@chr2:149639329..149639360
-
Hg19::chr2:179655525..179655536,-p@chr2:179655525..179655536
-
Hg19::chr2:27938986..27938991,+p@chr2:27938986..27938991
+
Hg19::chr3:42744130..42744141,-p4@HHATL
Hg19::chr4:111536685..111536696,-p2@ENST00000513690
Hg19::chr4:13842523..13842533,-p@chr4:13842523..13842533
-
Hg19::chr4:47833348..47833366,+p@chr4:47833348..47833366
+
Hg19::chr4:65180453..65180460,-p1@AX771276
Hg19::chr4:65366184..65366190,-p@chr4:65366184..65366190
-
Hg19::chr4:8321842..8321846,+p5@ENST00000509453
Hg19::chr5:102201562..102201573,+p7@PAM
Hg19::chr5:102201574..102201598,+p4@PAM
Hg19::chr5:102201610..102201628,+p3@PAM
Hg19::chr5:172671810..172671816,-p@chr5:172671810..172671816
-
Hg19::chr5:65736120..65736128,-p@chr5:65736120..65736128
-
Hg19::chr5:65736176..65736194,-p@chr5:65736176..65736194
-
Hg19::chr6:118869482..118869497,+p2@PLN
Hg19::chr6:118869507..118869518,+p3@PLN
Hg19::chr6:118880031..118880048,+p5@PLN
Hg19::chr6:118880085..118880101,+p4@PLN
Hg19::chr7:44178513..44178525,+p@chr7:44178513..44178525
+
Hg19::chr7:44179972..44179982,-p2@MYL7
Hg19::chr7:44180643..44180652,-p3@MYL7
Hg19::chr7:44180921..44180937,-p1@MYL7
Hg19::chr8:19540485..19540506,-p20@CSGALNACT1
Hg19::chr8:52567465..52567476,-p@chr8:52567465..52567476
-
Hg19::chr9:134165281..134165287,+p3@PPAPDC3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0003012muscle system process0.00281616180046562
GO:0006936muscle contraction0.00281616180046562
GO:0004598peptidylamidoglycolate lyase activity0.0276698457553279
GO:0016459myosin complex0.0331984391158079
GO:0042030ATPase inhibitor activity0.0331984391158079
GO:0004504peptidylglycine monooxygenase activity0.0347557543960679
GO:0045822negative regulation of heart contraction0.0347557543960679
GO:0008015blood circulation0.0347557543960679
GO:0003013circulatory system process0.0347557543960679
GO:0003008system process0.0347557543960679
GO:0007517muscle development0.0347557543960679
GO:0002026regulation of the force of heart contraction0.0432322685227638
GO:0048738cardiac muscle development0.0432322685227638
GO:0055082cellular chemical homeostasis0.0432322685227638
GO:0006873cellular ion homeostasis0.0432322685227638
GO:0016842amidine-lyase activity0.0432322685227638
GO:0050801ion homeostasis0.0432322685227638
GO:0016715oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen0.0432322685227638
GO:0005246calcium channel regulator activity0.0432322685227638
GO:0065008regulation of biological quality0.0432322685227638
GO:0051924regulation of calcium ion transport0.0432322685227638
GO:0005790smooth endoplasmic reticulum0.0432322685227638
GO:0007271synaptic transmission, cholinergic0.0432322685227638
GO:0005892nicotinic acetylcholine-gated receptor-channel complex0.0443017627326371
GO:0015629actin cytoskeleton0.0443017627326371
GO:0048878chemical homeostasis0.0443017627326371
GO:0000146microfilament motor activity0.0443687273673285
GO:0016840carbon-nitrogen lyase activity0.0443687273673285
GO:0030048actin filament-based movement0.0456872947973257
GO:0043269regulation of ion transport0.046917065715841



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell3.48e-10180
fibroblast3.35e-0775
Uber Anatomy
Ontology termp-valuen
adult organism6.81e-35115
neural plate7.65e-1486
presumptive neural plate7.65e-1486
central nervous system9.86e-1482
multi-cellular organism1.50e-13659
neural tube1.68e-1357
neural rod1.68e-1357
future spinal cord1.68e-1357
neural keel1.68e-1357
regional part of nervous system3.70e-1394
nervous system3.70e-1394
neurectoderm1.90e-1290
anterior neural tube8.43e-1242
organism subdivision1.16e-11365
regional part of forebrain2.44e-1141
forebrain2.44e-1141
future forebrain2.44e-1141
regional part of brain3.65e-1159
brain9.98e-1169
future brain9.98e-1169
pre-chordal neural plate5.66e-1061
anatomical system9.16e-10625
anatomical group1.64e-09626
telencephalon3.41e-0834
gray matter3.47e-0834
brain grey matter3.47e-0834
ectoderm-derived structure3.55e-08169
multi-tissue structure6.23e-08347
regional part of telencephalon7.49e-0833
embryo7.85e-08612
head1.25e-07123
cerebral hemisphere1.48e-0732
ectoderm1.54e-07173
presumptive ectoderm1.54e-07173
anterior region of body1.58e-07129
craniocervical region1.58e-07129
epithelium3.51e-07309
cell layer3.67e-07312


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


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