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Coexpression cluster:C1509

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Full id: C1509_heart_left_frontal_occipital_medial_brain_putamen



Phase1 CAGE Peaks

Hg19::chr3:123167930..123167945,-p@chr3:123167930..123167945
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Hg19::chr3:123167961..123167975,-p@chr3:123167961..123167975
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Hg19::chr3:192445212..192445229,-p5@FGF12
Hg19::chr3:192445319..192445395,-p1@FGF12
Hg19::chr7:82039889..82039899,-p@chr7:82039889..82039899
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Hg19::chr7:82039926..82039962,-p@chr7:82039926..82039962
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism7.24e-98114
neural tube1.39e-6456
neural rod1.39e-6456
future spinal cord1.39e-6456
neural keel1.39e-6456
regional part of nervous system9.69e-6053
regional part of brain9.69e-6053
regional part of forebrain1.33e-5541
forebrain1.33e-5541
anterior neural tube1.33e-5541
future forebrain1.33e-5541
neural plate7.78e-5182
presumptive neural plate7.78e-5182
neurectoderm6.53e-5086
central nervous system1.36e-4881
brain6.41e-4868
future brain6.41e-4868
telencephalon1.50e-4634
brain grey matter3.66e-4634
gray matter3.66e-4634
nervous system4.00e-4689
cerebral hemisphere4.51e-4332
regional part of telencephalon6.61e-4332
ecto-epithelium1.81e-38104
pre-chordal neural plate4.33e-3861
structure with developmental contribution from neural crest1.14e-37132
neocortex8.79e-3520
regional part of cerebral cortex1.92e-3422
cerebral cortex1.10e-2925
pallium1.10e-2925
organ system subdivision1.28e-27223
ectoderm-derived structure1.30e-26171
ectoderm1.30e-26171
presumptive ectoderm1.30e-26171
tube4.41e-22192
anatomical conduit4.22e-19240
anatomical cluster4.86e-19373
basal ganglion1.61e-189
nuclear complex of neuraxis1.61e-189
aggregate regional part of brain1.61e-189
collection of basal ganglia1.61e-189
cerebral subcortex1.61e-189
neural nucleus2.13e-189
nucleus of brain2.13e-189
multi-tissue structure4.30e-17342
telencephalic nucleus2.94e-157
organ part3.31e-14218
gyrus2.11e-126
organ7.35e-12503
epithelium7.96e-12306
cell layer1.52e-11309
posterior neural tube8.16e-1115
chordal neural plate8.16e-1115
parietal lobe1.21e-105
occipital lobe2.82e-105
diencephalon3.13e-107
future diencephalon3.13e-107
temporal lobe4.33e-106
corpus striatum9.46e-104
striatum9.46e-104
ventral part of telencephalon9.46e-104
future corpus striatum9.46e-104
embryo1.77e-09592
developing anatomical structure5.69e-09581
multi-cellular organism5.84e-09656
embryonic structure6.20e-09564
germ layer1.22e-08560
germ layer / neural crest1.22e-08560
embryonic tissue1.22e-08560
presumptive structure1.22e-08560
germ layer / neural crest derived structure1.22e-08560
epiblast (generic)1.22e-08560
segmental subdivision of nervous system3.10e-0813
brainstem4.25e-086
anatomical system6.83e-08624
anatomical group7.69e-08625
caudate-putamen9.17e-083
dorsal striatum9.17e-083
cardiac chamber2.50e-073
valve2.66e-073
cardiac mesenchyme2.66e-073
cardial valve2.66e-073
tunica intima2.66e-073
heart layer2.66e-073
endocardium2.66e-073
endocardial cushion2.66e-073
presumptive endocardium2.66e-073
frontal cortex4.50e-073
compound organ4.98e-0768
segmental subdivision of hindbrain6.07e-0712
hindbrain6.07e-0712
presumptive hindbrain6.07e-0712


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.321379
MA0004.10.558729
MA0006.11.01439
MA0007.10.539222
MA0009.11.03681
MA0014.10.262822
MA0017.10.432438
MA0019.10.7124
MA0024.10.929647
MA0025.11.17262
MA0027.12.65688
MA0028.10.408079
MA0029.10.949428
MA0030.10.937696
MA0031.10.871496
MA0038.10.665566
MA0040.10.955415
MA0041.10.578072
MA0042.10.544748
MA0043.11.03713
MA0046.11.02569
MA0048.10.906394
MA0050.10.545671
MA0051.10.661179
MA0052.12.20326
MA0055.10.808182
MA0056.10
MA0057.10.882847
MA0058.10.458909
MA0059.10.457555
MA0060.10.267412
MA0061.10.671725
MA0063.10
MA0066.10.66601
MA0067.11.35893
MA0068.10.578694
MA0069.11.02175
MA0070.11.01032
MA0071.10.625297
MA0072.11.00572
MA0073.10.347876
MA0074.10.660398
MA0076.10.475586
MA0077.10.997832
MA0078.10.763954
MA0081.10.457725
MA0083.11.04447
MA0084.11.5477
MA0087.11.00322
MA0088.10.32124
MA0089.10
MA0090.10.490736
MA0091.10.561458
MA0092.10.522012
MA0093.10.394379
MA0095.10
MA0098.10
MA0100.11.62836
MA0101.10.397846
MA0103.10.993014
MA0105.10.830067
MA0106.10.70837
MA0107.10.320267
MA0108.20.868347
MA0109.10
MA0111.10.504913
MA0113.10.725375
MA0114.10.314898
MA0115.11.28169
MA0116.10.865577
MA0117.11.07516
MA0119.10.440684
MA0122.11.10154
MA0124.11.23968
MA0125.11.15445
MA0130.10
MA0131.10.782708
MA0132.10
MA0133.10
MA0135.11.06778
MA0136.10.672893
MA0139.10.226048
MA0140.10.622527
MA0141.10.455728
MA0142.10.838805
MA0143.10.725558
MA0144.10.299851
MA0145.10.347815
MA0146.10.0213085
MA0147.10.327615
MA0148.10.584698
MA0149.10.612449
MA0062.20.23336
MA0035.20.621793
MA0039.21.13151
MA0138.20.765223
MA0002.20.255126
MA0137.20.414885
MA0104.20.26661
MA0047.20.695777
MA0112.20.332548
MA0065.20.718489
MA0150.11.21643
MA0151.10
MA0152.10.629368
MA0153.11.13732
MA0154.10.413181
MA0155.10.65596
MA0156.10.417278
MA0157.10.810597
MA0158.10
MA0159.10.328286
MA0160.10.600559
MA0161.10
MA0162.10.150673
MA0163.13.1714
MA0164.10.738243
MA0080.21.02158
MA0018.20.709805
MA0099.20.629739
MA0079.26.53042
MA0102.21.58513
MA0258.10.289793
MA0259.10.336472
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.