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Coexpression cluster:C3267

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Full id: C3267_temporal_parietal_duodenum_Chondrocyte_colon_occipital_Neural



Phase1 CAGE Peaks

  Short description
Hg19::chr12:24097201..24097216,- p10@SOX5
Hg19::chr12:24097236..24097256,- p9@SOX5
Hg19::chr12:24102576..24102623,- p2@SOX5


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
astrocyte of the cerebral cortex1.55e-083
collagen secreting cell6.35e-086
chondroblast6.35e-086
chondrocyte6.35e-086
GAG secreting cell9.93e-089
carbohydrate secreting cell9.93e-089
Uber Anatomy
Ontology termp-valuen
neural tube1.25e-5856
neural rod1.25e-5856
future spinal cord1.25e-5856
neural keel1.25e-5856
telencephalon1.61e-5734
brain grey matter2.82e-5734
gray matter2.82e-5734
cerebral hemisphere3.39e-5732
regional part of nervous system1.55e-5553
regional part of brain1.55e-5553
regional part of telencephalon1.15e-5232
central nervous system5.28e-5281
regional part of forebrain4.57e-5041
forebrain4.57e-5041
anterior neural tube4.57e-5041
future forebrain4.57e-5041
brain5.38e-4668
future brain5.38e-4668
nervous system9.07e-4689
cerebral cortex4.53e-4425
pallium4.53e-4425
neural plate1.71e-4182
presumptive neural plate1.71e-4182
neurectoderm4.32e-3986
regional part of cerebral cortex2.85e-3722
neocortex1.03e-3620
pre-chordal neural plate1.76e-3361
ecto-epithelium1.48e-30104
adult organism3.09e-28114
organ system subdivision8.88e-27223
structure with developmental contribution from neural crest1.92e-26132
ectoderm-derived structure4.10e-21171
ectoderm4.10e-21171
presumptive ectoderm4.10e-21171
brainstem7.71e-166
temporal lobe5.84e-156
tube5.91e-15192
basal ganglion6.48e-159
nuclear complex of neuraxis6.48e-159
aggregate regional part of brain6.48e-159
collection of basal ganglia6.48e-159
cerebral subcortex6.48e-159
neural nucleus2.21e-149
nucleus of brain2.21e-149
organ part1.61e-13218
anatomical cluster1.78e-13373
gyrus3.25e-126
corpus striatum6.15e-124
striatum6.15e-124
ventral part of telencephalon6.15e-124
future corpus striatum6.15e-124
posterior neural tube2.99e-1015
chordal neural plate2.99e-1015
telencephalic nucleus4.63e-107
multi-tissue structure4.64e-10342
parietal lobe5.51e-105
anatomical conduit6.45e-10240
limbic system8.48e-105
occipital lobe2.69e-095
caudate-putamen3.43e-093
dorsal striatum3.43e-093
pons5.35e-093
medulla oblongata1.55e-083
myelencephalon1.55e-083
future myelencephalon1.55e-083
epithelium7.11e-08306
cell layer1.07e-07309
segmental subdivision of hindbrain1.43e-0712
hindbrain1.43e-0712
presumptive hindbrain1.43e-0712
amygdala5.88e-072
segmental subdivision of nervous system6.16e-0713
middle temporal gyrus7.84e-072


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0471418
MA0004.10.826076
MA0006.10.639288
MA0007.10.804807
MA0009.11.3275
MA0014.10.118426
MA0017.10.686276
MA0019.12.26702
MA0024.11.21731
MA0025.11.46617
MA0027.12.95767
MA0028.10.658629
MA0029.11.23771
MA0030.11.22561
MA0031.11.15713
MA0038.10.94098
MA0040.11.24388
MA0041.10.847069
MA0042.10.810843
MA0043.11.32783
MA0046.11.31611
MA0048.10.341392
MA0050.10.81185
MA0051.10.936307
MA0052.11.24796
MA0055.10.190716
MA0056.10
MA0057.11.59304
MA0058.10.716037
MA0059.10.714521
MA0060.11.23283
MA0061.10.456531
MA0063.10
MA0066.10.941452
MA0067.11.65513
MA0068.10.405474
MA0069.11.31207
MA0070.11.30033
MA0071.10.897953
MA0072.11.29561
MA0073.10.0834661
MA0074.10.935474
MA0076.10.734647
MA0077.11.28751
MA0078.11.04495
MA0081.10.714712
MA0083.11.33535
MA0084.11.84562
MA0087.11.29304
MA0088.11.31954
MA0089.10
MA0090.10.751469
MA0091.10.829044
MA0092.10.785956
MA0093.10.642957
MA0095.10
MA0098.10
MA0100.10.956299
MA0101.10.646932
MA0103.10.628063
MA0105.10.31555
MA0106.10.986396
MA0107.10.556367
MA0108.21.15387
MA0109.10
MA0111.10.767139
MA0113.11.00436
MA0114.10.549955
MA0115.11.57693
MA0116.10.560723
MA0117.11.36676
MA0119.10.695578
MA0122.11.39371
MA0124.11.53432
MA0125.11.44766
MA0130.10
MA0131.11.06461
MA0132.10
MA0133.10
MA0135.11.35921
MA0136.10.948776
MA0139.10.440097
MA0140.10.894983
MA0141.10.712476
MA0142.11.12317
MA0143.11.00455
MA0144.10.531867
MA0145.10.273764
MA0146.10.107247
MA0147.10.565108
MA0148.10.854239
MA0149.10.884158
MA0062.20.449458
MA0035.20.894194
MA0039.20.195278
MA0138.21.04628
MA0002.20.476938
MA0137.20.666381
MA0104.20.491226
MA0047.20.973066
MA0112.20.264678
MA0065.20.277623
MA0150.10.744617
MA0151.10
MA0152.10.902317
MA0153.11.43021
MA0154.10.838867
MA0155.10.256269
MA0156.10.669101
MA0157.11.09377
MA0158.10
MA0159.10.565904
MA0160.10.871361
MA0161.10
MA0162.10.149099
MA0163.10.122425
MA0164.11.01792
MA0080.20.643061
MA0018.20.987913
MA0099.20.902716
MA0079.21.22771
MA0102.21.88331
MA0258.10.519674
MA0259.10.575594
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
ZZZ3#26009179.80440414507770.0124784379082580.0451555932469615



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.